Ida Karlsson
About me
I am Docent, Assistant professor, and leader of the research group Cardiometabolic epidemiology and aging. My main interest is combining genetic and longitudinal designs to understand complex aging-related traits. My primary research aim is to understand how obesity influences late-life health, by studying how differences among adiposity-related traits and why they have different associations with age-related diseases such as dementia, cardiovascular disease, and type-2 diabetes. I am also involved in several projects aiming to understand how different factors across the life course affect dementia risk, including genetic factors, lifestyle, and environmental exposures.
Research
Adiposity and the risk of age-related disease
The project aims to leverage the heterogeneity of adiposity-related traits, to understand better how adiposity influences the risk of cardiovascular disease, type 2 diabetes, and dementia. My hypothesis is that specific adiposity-related traits have different effects on the risk of the age-related diseases, and that these differences are explained by differences in e.g. metabolic factors or accelerated aging. I study adiposity in general (e.g. BMI and body fat distribution), and specific adiposity-related traits: a) metabolically unhealthy vs healthy adiposity, b) environmentally vs genetically driven adiposity, and c) adiposity measured in midlife vs late-life. These adiposity-related traits are associated with substantially increased, vs only slightly increased or even decreased risk of age-related disease (compared to having normal weight), and by studying what differs between them, I aim to advance our understanding of both the heterogeneity of overweight and of how adiposity in general affects late-life health.
The Interplay of Genes and Environment across Multiple Studies (IGEMS) consortium
I am part of the IGEMS consortium, which integrates data across twin studies of adult development and aging to address issues of gene-environment interplay in Alzheimer’s Disease and related dementias (ADRD). Within IGEMS, I lead studies of cardiometabolic risk factors of ADRD and am the lead of the Statistical Methods work group and the Genotyping and Polygenic Scores work group.
Teaching
Course director:
- An introduction to genetic and molecular epidemiology, Karolinska Institutet, from 2021 (PhD course, 1.5 credits)
- Statistical Methods, School of Health and Welfare, Jönköping University, 2020 (PhD course, 7.5 credits)
Lecturer:
Karolinska Institutet, from 2021:- Lectures on genetic epidemiology, cognition, and dementia (bachelor and master level)
- Leader of seminars, group work, laboratory assignments in epidemiology and biostatistics
School of Health and Welfare, Jönköping University, 2018-2020:
- Lectures on statistical methods (doctoral level)
- Lectures on cognition and dementia (bachelor and master level)
Supervision:
- Axel Ryding, research assistant (amanuens)
- Elsa Ojalehto, PhD student at Karolinska Institutet, Department of Medical Epidemiology and Biostatistics
- Emilija Romic (as co-supervisor), PhD student at Umeå University
- Martin Nakash, research assistant (amanuens)
- Otto-Emil Jutila (as co-supervisor), PhD student at the University of Edinburgh, Precision Medicine Doctoral Training Program
Former students:
- Peggy Ler, PhD student at Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, graduation November 2024. Thesis: Disentangling the body bass index, metabolic health and aging connection: weighty matters
- Anita Paul, master student from Stockholm University, Public health department, VT 2022
- Axel Ryding, medical degree student at Karolinska Institutet, HT 2023
- Elsa Ojalehto (as co-supervisor, now PhD student), master student from Stockholm University, Public health department, VT 2022
- Martin Nakash, medical degree student at Karolinska Institutet, VT 2024
Articles
- Article: INTERNATIONAL JOURNAL OF OBESITY. 2025;49(7):1327-1333
- Article: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE. 2025;16(3):e13824
- Article: ENVIRONMENTAL EPIDEMIOLOGY. 2025;9(1):e355
- Article: DIABETES OBESITY & METABOLISM. 2025;27(1):207-214
- Article: GEROSCIENCE. 2024;46(5):5003-5014
- Article: BMJ MENTAL HEALTH. 2024;27(1):e301064
- Article: AGING CELL. 2024;23(6):e14132
- Article: AGING CELL. 2024;23(6):e14135
- Article: GEROSCIENCE. 2024;46(2):2605-2617
- Article: ALZHEIMERS & DEMENTIA. 2024;20(3):1682-1692
- Article: INTERNATIONAL JOURNAL OF OBESITY. 2024;48(3):433-436
- Article: GEROSCIENCE. 2024;46(1):961-968
- Article: NEUROEPIDEMIOLOGY. 2024;58(4):256-263
- Article: JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES. 2024;79(1):gbad153
- Article: EPIGENETICS. 2023;18(1):2158285
- Article: BRAIN. 2023;146(12):4891-4902
- Article: SOCIAL SCIENCE & MEDICINE. 2023;324:115882
- Article: ECLINICALMEDICINE. 2023;58:101943
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2022;37(12):1261-1271
- Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):296
- Article: BRAIN COMMUNICATIONS. 2022;4(1):fcab308
- Article: AGE AND AGEING. 2021;50(6):2174-2182
- Article: BMC MEDICINE. 2021;19(1):248
- Article: NATURE GENETICS. 2021;53(9):1276-1282
- Article: CLINICAL EPIGENETICS. 2021;13(1):129
- Article: NATURE COMMUNICATIONS. 2021;12(1):3417
- Article: CLINICAL EPIGENETICS. 2021;13(1):85
- Article: SCIENTIFIC REPORTS. 2021;11(1):7206
- Article: ALZHEIMER'S AND DEMENTIA: TRANSLATIONAL RESEARCH AND CLINICAL INTERVENTIONS. 2021;7(1):e12176
- Article: JOURNAL OF INTERNAL MEDICINE. 2020;288(2):234-247
- Article: BMC MEDICINE. 2020;18(1):131
- Article: INTERNATIONAL JOURNAL OF OBESITY. 2020;44(6):1397-1405
- Article: ALZHEIMER'S AND DEMENTIA: DIAGNOSIS, ASSESSMENT AND DISEASE MONITORING. 2020;12(1):e12049
- Article: CLINICAL EPIGENETICS. 2019;11(1):187
- Article: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY. 2019;27(11):1177-1188
- Journal article: BEHAVIOR GENETICS. 2019;:487-557
- Article: CLINICAL EPIGENETICS. 2019;11(1):130
- Article: STATISTICAL METHODS IN MEDICAL RESEARCH. 2019;28(6):1911-1923
- Article: BMC MEDICINE. 2019;17(1):94
- Article: NATURE GENETICS. 2019;51(3):404-413
- Article: PSYCHOLOGICAL MEDICINE. 2019;49(2):260-267
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2018;33(10):977-987
- Article: NATURE GENETICS. 2018;50(7):912-919
- Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2018;47(3):899-907
- Article: NATURE COMMUNICATIONS. 2018;9(1):2098
- Article: JOURNAL OF ALZHEIMERS DISEASE. 2018;61(4):1301-1310
- Article: NEUROLOGY. 2018;90(4):e291-e297
- Article: AGING-US. 2017;9(12):2629-2646
- Article: CIRCULATION RESEARCH. 2017;121(3):214-219
- Article: TRANSLATIONAL PSYCHIATRY. 2017;7(5):e1142
- Article: NEUROBIOLOGY OF AGING. 2015;36(4):1751-1756
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Employments
- Assistant Professor, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2022-2028
- Postdoctoral Researcher, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2021-2022
- Postdoctoral Researcher, School of Health and Welfare, Institute of Gerontology, Jönköping University, 2017-2020
- Phd Student, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2012-2017
- R&D Trainee, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2011-2012
Degrees and Education
- Docent, Karolinska Institutet, 2024
- Degree Of Doctor Of Philosophy, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2017
- Master Of Medical Science, Karolinska Institutet, 2010
Leadership and responsibility assignments
- Course coordinator, An Introduction to Genetic and MolecularEpidemiology (3077), Karolinska Institutet, https://ki.se/en/meb/education/doctoral-courses/an-introduction-to-genetic-and-molecular-epidemiology, 2022-
Committee work
- Member, Junior Faculty Steering Group, Karolinska Institutet, 2024-
- Vice chair, MEB Departmental Junior Faculty Group, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2021-
Visiting research fellowships
- Fulbright Scholar, University of California, Riverside, https://fulbrightscholars.org/grantee/ida-kristin-karlsson, 2019-2020
- Eurolife Postdoc Mobility and Knowledge Exchange, University of Edinburgh