Heela Sarlus
About me
I am investigating the role of myeloid responses, in particular microglia and macrophages, in the brain in the context of neurodegenerative diseases such as multiple sclerosis (MS), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) with the aim to identify novel therapeutic targets for these diseases.
In neurodegenerative diseases, myeloid cells are implicated in causing damage to the central nervous system (CNS) but also promoting tissue repair. This dichotomous response governed by different myeloid activation states has the potential to impact disease trajectory. We are using human placenta-derived stem cells to modulate myeloid cells to promote reparative processes in the CNS and reduce neuroinflammation in neurodegenerative diseases.
Teaching
Teaching biochemistry in Scandinavian Chiropractor institute, Stockholm,
Articles
- Article: SCIENTIFIC REPORTS. 2024;14(1):24846Min J-H; Sarlus H; Oasa S; Harris RA
- Article: BRAIN BEHAVIOR AND IMMUNITY. 2024;121:43-55Spielbauer J; Glotfelty EJ; Sarlus H; Harris RA; Heijtz RD; Karlsson TE
- Article: METALLOMICS. 2024;16(5):mfae019Min J-H; Sarlus H; Harris RA
- Journal article: TRANSPLANTATION. 2023;107(10):49Sarlus H; Zhu K; Guo Y; Balasingh VJ; Min J-H; Cuesta IB; Bencina S; Harris R; Gramignoli R
- Article: ACTA PHARMACOLOGICA SINICA. 2023;44(4):766-779Sun J-X; Zhu K-Y; Wang Y-M; Wang D-J; Zhang M-Z; Sarlus H; Benito-Cuesta I; Zhao X-Q; Zou Z-F; Zhong Q-Y; Feng Y; Wu S; Wang Y-Q; Harris RA; Wang J
- Article: EMBO REPORTS. 2022;23(7):e54499Zhu K; Wang Y; Sarlus H; Geng K; Nutma E; Sun J; Kung S-Y; Bay C; Han J; Min J-H; Benito-Cuesta I; Lund H; Amor S; Wang J; Zhang X-M; Kutter C; Guerreiro-Cacais AO; Hogberg B; Harris RA
- Article: ACTA BIOMATERIALIA. 2022;142:36-48Samanta S; Rangasami VK; Sarlus H; Samal JRK; Evans AD; Parihar VS; Varghese OP; Harris RA; Oommen OP
- Article: HEARING RESEARCH. 2022;415:108395Versteegh CPC; Tserga EM; Fontana J; Moreno-Paublete R; Sarlus H; Zisiadis G-AR; Cederroth C; Canlon B
- Article: EMBO JOURNAL. 2021;40(24):e108662Kummer MP; Ising C; Kummer C; Sarlus H; Griep A; Vieira-Saecker A; Schwartz S; Halle A; Bruckner M; Handler K; Schultze JL; Beyer M; Latz E; Heneka MT
- Journal article: ALZHEIMERS & DEMENTIA. 2021;17(S3)Villacampa N; Sarlus H; Martorell P; Slutzkin I; Mcmanus RM; Beyer M; Segal E; Heneka MT
- Article: CELL REPORTS. 2021;36(13):109758Milon B; Shulman ED; So KS; Cederroth CR; Lipford EL; Sperber M; Sellon JB; Sarlus H; Pregernig G; Shuster B; Song Y; Mitra S; Orvis J; Margulies Z; Ogawa Y; Shults C; Depireux DA; Palermo AT; Canlon B; Burns J; Elkon R; Hertzano R
- Article: NEUROSCIENCE. 2020;448:14-27Sarlus H; Codita A; Wang X; Cedazo-Minguez A; Schultzberg M; Oprica M
- Article: FASEB JOURNAL. 2020;34(10):13978-13992Tserga E; Moreno-Paublete R; Sarlus H; Bjorn E; Guimaraes E; Goritz C; Cederroth CR; Canlon B
- Article: JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA. 2019;146(5):3960-3966Fontana JM; Tserga E; Sarlus H; Canlon B; Cederroth C
- Article: CURRENT BIOLOGY. 2019;29(15):2477-2487.e6Cederroth CR; Park J-S; Basinou V; Weger BD; Tserga E; Sarlus H; Magnusson AK; Kadri N; Gachon F; Canton B
- Article: JOURNAL OF ALZHEIMERS DISEASE. 2015;48(2):495-505Sarlus H; Eyjolfsdottir H; Eriksdotter M; Oprica M; Schultzberg M
- Journal article: ALZHEIMERS & DEMENTIA. 2014;10(4S_Part_8):p336Sarlus H; Codita A; Minguez AC; Oprica M; Schultzberg M
- Article: JOURNAL OF NEUROINFLAMMATION. 2013;10:99Sarlus H; Wang X; Cedazo-Minguez A; Schultzberg M; Oprica M
- Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2012;16(10):2401-2412Sarlus H; Hoglund CO; Karshikoff B; Wang X; Lekander M; Schultzberg M; Oprica M
All other publications
- Corrigendum: SCIENTIFIC REPORTS. 2024;14(1):30574Min J-H; Sarlus H; Oasa S; Harris RA
- Review: FRONTIERS IN NEUROSCIENCE. 2024;18:1467333Min J-H; Sarlus H; Harris RA
- Review: FRONTIERS IN MOLECULAR NEUROSCIENCE. 2024;17:1408159Min J-H; Sarlus H; Harris RA
- Preprint: BIORXIV. 2023Zhu K; Min J-H; Joshua V; Liu Y; Pieber M; Suerth V; Sarlus H; Harris R; Lund H
- Preprint: BIORXIV. 2021Zhu K; Wang Y; Sarlus H; Geng K; Nutma E; Sun J; Kung S-Y; Bay C; Han J; Lund H; Amor S; Wang J; Zhang X; Kutter C; Guerreiro Cacais AO; Högberg B; Harris R
- Preprint: SSRN ELECTRONIC JOURNAL. 2021Samanta S; Rangasami VK; Sarlus H; Samal JRK; Evans AD; Parihar VS; Varghese OP; Harris RA; Oommen OP
- Review: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2020;8(1):217Han J; Sarlus H; Wszolek ZK; Karrenbauer VD; Harris RA
- Review: HEARING RESEARCH. 2019;377:53-60Sarlus H; Fontana JM; Tserga E; Meltser I; Cederroth CR; Canlon B
- Review: JOURNAL OF CLINICAL INVESTIGATION. 2017;127(9):3240-3249Sarlus H; Heneka MT
Employments
- Research Specialist, Department of Clinical Neuroscience, Karolinska Institutet, 2022-
Degrees and Education
- Degree Of Doctor Of Philosophy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2015