Heela Sarlus
About me
I am investigating the role of myeloid responses, in particular microglia and macrophages, in the brain in the context of neurodegenerative diseases such as multiple sclerosis (MS), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) with the aim to identify novel therapeutic targets for these diseases.
In neurodegenerative diseases, myeloid cells are implicated in causing damage to the central nervous system (CNS) but also promoting tissue repair. This dichotomous response governed by different myeloid activation states has the potential to impact disease trajectory. We are using human placenta-derived stem cells to modulate myeloid cells to promote reparative processes in the CNS and reduce neuroinflammation in neurodegenerative diseases.
Teaching
Teaching biochemistry in Scandinavian Chiropractor institute, Stockholm,
Articles
- Article: SCIENTIFIC REPORTS. 2024;14(1):24846
- Article: BRAIN BEHAVIOR AND IMMUNITY. 2024;121:43-55
- Article: METALLOMICS. 2024;16(5):mfae019
- Journal article: TRANSPLANTATION. 2023;107(10):49
- Article: ACTA PHARMACOLOGICA SINICA. 2023;44(4):766-779
- Article: EMBO REPORTS. 2022;23(7):e54499
- Article: ACTA BIOMATERIALIA. 2022;142:36-48
- Article: HEARING RESEARCH. 2022;415:108395
- Article: EMBO JOURNAL. 2021;40(24):e108662
- Journal article: ALZHEIMERS & DEMENTIA. 2021;17(S3)
- Article: CELL REPORTS. 2021;36(13):109758
- Article: NEUROSCIENCE. 2020;448:14-27
- Article: FASEB JOURNAL. 2020;34(10):13978-13992
- Article: JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA. 2019;146(5):3960-3966
- Article: CURRENT BIOLOGY. 2019;29(15):2477-2487.e6
- Article: JOURNAL OF ALZHEIMERS DISEASE. 2015;48(2):495-505
- Journal article: ALZHEIMERS & DEMENTIA. 2014;10(4S_Part_8):p336
- Article: JOURNAL OF NEUROINFLAMMATION. 2013;10:99
- Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2012;16(10):2401-2412
All other publications
- Corrigendum: SCIENTIFIC REPORTS. 2024;14(1):30574
- Review: FRONTIERS IN MOLECULAR NEUROSCIENCE. 2024;17:1408159
- Review: FRONTIERS IN NEUROSCIENCE. 2024;18:1467333
- Preprint: BIORXIV. 2023
- Preprint: SSRN ELECTRONIC JOURNAL. 2021
- Review: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2020;8(1):217
- Review: HEARING RESEARCH. 2019;377:53-60
- Review: JOURNAL OF CLINICAL INVESTIGATION. 2017;127(9):3240-3249
Employments
- Research Specialist, Department of Clinical Neuroscience, Karolinska Institutet, 2022-
Degrees and Education
- Degree Of Doctor Of Philosophy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2015