Hans Grönlund
Principal Researcher | Docent
E-mail: hans.gronlund@ki.se
Visiting address: , Stockholm
Postal address: K8 Klinisk neurovetenskap, K8 Neuro Grönlund, 171 77 Stockholm
About me
- I am associate professor of immunology, since 2010 heading Therapeutic immune
design Unit (TID) at the Department of Clinical neuroscience. To shed light
and knowledge motivates me, particularly in multi disciplinary projects
aiming to translate basal immunological findings to diagnostics and
curative approaches for clinical use. Our research has important
possibilities for curative attempts in multiple sclerosis, allergy and
cancer.
I started as a PhD student 2000 and defended my thesis 2005 at Karolinska
institutet with the title ”Diagnosis and treatment of IgE-mediated
allergy: new approaches using recombinant allergens”.
Year 1996 to 2020 I have authored 93 peer reviewed scientific publications
in international journals. In addition I have experience from industry and is
founder of NEOGAP AB and Medi-tec AB.
Prof. Dr Alfred Kreissner-Preis (Austria), 1999
Stockholm Society of Allergology, ”Årets Rookie”, 2006
Konsul Th C Berghs Stiftelse. Pris för bästa avhandling, 2006.
Member of Editorial Board, Allergy, 2009-
Member of the Editorial Board, Int. Arch. All. & - Immunol., 2012
Associate professor of immunology at Karolinska institutet, 2011
Post doc. at Center for Allergy Research, IMM and Department of Medicine,
Karolinska institutet, 2005-11
PhD medical sciences, Karolinska institutet, 2000-05
BSc Stockholm University 1981
Research
- TID research focuses on translation of basic immunology into clinical use in
our main target areas hyper allergy, multiple sclerosis, (MS) and cancer.
We design and produce biomolecules with specific properties aiming
at superior diagnosis and curative treatment.
Our cancer projects focus on personal neoepitope predictions and ranking via
massive sequencing and bioinformatic filtering, protein production and
tumour-specific autologous T-cell expansion and transfer. We will start a
clinical trials 2021.
We use our in house developed T-cell platform to identify novel autoantigens
in multiple sclerosis. In this project we collaborate with research groups in
Sweden and Europe. The aim here is to develop superior diagnostics and
ultimately curative treatments.
In allergy we have a solid international reputation, particularly in allergy
to pets. Here we have developed novel diagnostics and vaccines for curative
treatments. My most cited publication as senior author with the title "The
recombinant allergen-based concept of component –resolved diagnostics and
immunotherapy (CRD and CRIT)" was published 1999 and paved the way
for world-wide used multiplex allergy diagnostics. In allergy we
collaborate with adult and childrens clinics, patient
organisations, "Small biotech enterprises" and not least researcher spread
over the world.
Articles
- Journal article: CYTOTHERAPY. 2024;26(6):e26-e27
- Journal article: FRONTIERS IN IMMUNOLOGY. 2024;15:1334720
- Article: EUROPEAN JOURNAL OF NEUROLOGY. 2023;30(12):3789-3798
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(23):16729
- Article: SCIENCE ADVANCES. 2023;9(20):eadg3032
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;77(10):2987-3001
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(13):6984
- Article: CLINICAL AND TRANSLATIONAL ALLERGY. 2022;12(5):e12149
- Article: SCIENCE ADVANCES. 2022;8(17):eabn1823
- Article: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2022;32(2):133-140
- Article: FRONTIERS IN ONCOLOGY. 2022;12:866763
- Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2022;183(11):1166-1177
- Article: ISCIENCE. 2021;24(9):103078
- Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2020;8(1):207
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;75(5):1269-1272
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;74(12):2461-2478
- Article: JOURNAL OF AUTOIMMUNITY. 2019;102:38-49
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;74(8):1472-1479
- Article: METHODSX. 2019;6:1635-1641
- Article: PLOS ONE. 2019;14(5):e0217208
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;142(4):1113-1120.e9
- Article: CELL. 2018;175(1):85-100.e23
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;72(4):590-597
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2016;71(10):1490-1495
- Article: JOURNAL OF IMMUNOLOGY. 2016;197(6):2063-2068
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2016;71(9):1366-1370
- Article: RESPIRATORY RESEARCH. 2016;17(1):69
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(8):2188-2193
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;70(12):1651-1655
- Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2015;191(5):574-583
- Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2014;25(6):558-564
- Article: RESPIRATORY MEDICINE. 2014;108(8):1234-1237
- Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2014;44(6):882-894
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;69(6):708-718
- Article: METHODS. 2014;66(1):86-95
- Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2014;25(2):187-192
- Article: PLOS ONE. 2014;9(10):e111041
- Journal article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;68(11):1484-1486
- Article: JOURNAL OF IMMUNOLOGY. 2013;191(4):1529-1535
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;68(4):549-552
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;68(5):585-592
- Article: MOLECULAR NUTRITION AND FOOD RESEARCH. 2012;56(12):1894-1905
- Journal article: PNEUMOLOGIE. 2012;66(11)
- Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2012;23(4):376-384
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2012;67(6):751-757
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2012;129(5):1290-1296
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2012;67(5):661-669
- Article: VACCINE. 2011;29(48):8965-8973
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2011;127(6):1562-U375
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2011;127(4):1024-1028
- Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2011;22(1):9-18
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2011;66(2):255-263
- Article: PLOS ONE. 2011;6(9):e24558
- Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2011;155(2):111-118
- Article: JOURNAL OF MOLECULAR BIOLOGY. 2010;401(1):68-83
- Article: JOURNAL OF AUTOIMMUNITY. 2010;34(2):73-79
- Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2010;21(2):277-283
- Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2009;39(8):1199-1208
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2009;206(7):1535-1547
- Article: JOURNAL OF CARDIOVASCULAR RISK. 2009;16(3):382-386
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2009;64(6):905-912
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2009;64(6):919-926
- Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2009;65(Pt 5):467-471
- Article: ATHEROSCLEROSIS. 2009;203(2):528-532
- Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2008;38(12):959-965
- Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2008;38(8):1275-1281
- Article: LAKARTIDNINGEN. 2008;105(26-27):1942-1945
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2008;63(5):518-526
- Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2008;146(1):1-10
- Journal article: WORLD ALLERGY ORGANIZATION JOURNAL. 2007;&NA;(&NA;):s136
- Article: JOURNAL OF MOLECULAR BIOLOGY. 2007;370(4):714-727
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;119(3):640-645
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;119(2):351-358
- Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2007;37(1):116-124
- Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2006;310(1-2):117-125
- Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2005;138(1):59-66
- Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2005;35(5):657-663
- Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2005;61(Pt 2):232-234
- Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2005;60(2):185-191
- Article: IMMUNOLOGY. 2004;113(2):253-259
- Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;59(6):622-623
- Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2004;113(2):s94-s95
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(41):40144-40151
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(39):37730-37735
- Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2003;132(1):25-26
- Article: ACTA CRYSTALLOGRAPHICA SECTION D: BIOLOGICAL CRYSTALLOGRAPHY. 2003;59(Pt 6):1103-1105
- Article: IMMUNOLOGY. 2002;107(4):523-529
- Article: THE FEBS JOURNAL. 2002;269(11):2647-2655
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2001;108(3):409-416
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(3):918-928
- Article: HORMONE AND METABOLIC RESEARCH. 2000;32(4):133-138
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1999;104(5):969-977
- Article: APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 1999;65(9):4134-4140
- Article: JOURNAL OF CLINICAL INVESTIGATION. 1999;103(11):1571-1578
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1998;102(4):579-591
- Article: JOURNAL OF IMMUNOLOGICAL METHODS. 1998;213(1):87-97
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1997;239(1):197-204
- Article: CLINICAL AND EXPERIMENTAL ALLERGY. 1996;26(12):1411-1419
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1996;98(3):652-658
- Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1996;97(1):385
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All other publications
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:482-483
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:36-37
- Conference publication: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10:A685
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):234-235
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):103-104
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):233-234
- Letter: CLINICAL AND EXPERIMENTAL ALLERGY. 2021;51(9):1221-1224
- Letter: ALLERGY, ASTHMA AND IMMUNOLOGY RESEARCH. 2021;13(4):668-670
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):348
- Preprint: SSRN ELECTRONIC JOURNAL. 2021
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):344-345
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):50-51
- Letter: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;75(10):2668-2670
- Review: WORLD ALLERGY ORGANIZATION JOURNAL. 2020;13(5):100118
- Review: EXPERT OPINION ON BIOLOGICAL THERAPY. 2019;19(8):811-827
- Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(4):1658-1659
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2019;49:746-747
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:221
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;74:223
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;74:174-175
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):340
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;72:340
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2016;71:190
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2016;71:612
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2016;71:397
- Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;135(2):AB180
- Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;135(2):AB84
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;70:517
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;70:173
- Book chapter: MOLECULAR VACCINES. 2014;p. 623-631
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2014;79(6):477
- Letter: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;68(11):1485-1486
- Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2013;42
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;68:135-136
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;68:35
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;68:535
- Conference publication: 2012;:a1415
- Conference publication: IMMUNOLOGY. 2012;137:443
- Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2012;40
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2011;66:291-292
- Review: HUMAN VACCINES. 2010;6(12):970-977
- Review: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2010;151(4):265-274
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2010;65:105
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2010;65:668
- Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2009;123(5):1189-1191
- Conference publication: EUROPEAN HEART JOURNAL. 2009;30:773
- Conference publication: CLINICAL CHEMISTRY. 2009;55(6):A57
- Conference publication: EUROPEAN HEART JOURNAL. 2009;30:774
- Conference publication: CLINICAL CHEMISTRY. 2009;55(6):A58
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2009;64:149-150
- Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):78
- Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):78
- Conference publication: EUROPEAN HEART JOURNAL. 2008;29:628
- Conference publication: CLINICAL CHEMISTRY. 2008;54(6):A153
- Conference publication: PLACENTA. 2008;29(8):A49
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;68(2):230
- Conference publication: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2008;51(10):A343
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2008;63:232
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2008;63:223
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;62:251-252
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;62:250
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;62:249
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;62:149-150
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;62:76-77
- Meeting abstract: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;117(2):S327
- Thesis / dissertation: 2005
- Published conference paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(Suppl 2):14677-14682
- Conference publication: ACTA CRYSTALLOGRAPHICA SECTION A: FOUNDATIONS AND ADVANCES. 2004;60:S174
- Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2002;57:187
- Meeting abstract: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):s52
- Review: CLINICAL AND EXPERIMENTAL ALLERGY. 1999;29(7):896-904
- Published conference paper: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 1999;118(2-4):116-118
- Review: BIOLOGICAL CHEMISTRY. 1999;380(7-8):815-824
- Book chapter: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 1996;p. 111-116
- Book chapter: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 1996;p. 185-196
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Grants
- Swedish Research Council1 June 2012 - 31 May 2016
Employments
- Principal Researcher, Department of Clinical Neuroscience, Karolinska Institutet, 2022-
Degrees and Education
- Docent, Karolinska Institutet, 2011
- Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2005