Eva Isaksson

Eva Isaksson

Affiliated to Research
Telephone: +46852482621
Visiting address: Entrévägen 2, 18257 Danderyd
Postal address: D1 Kliniska vetenskaper, Danderyds sjukhus, D1 Neurologi Cerebrovaskulära sjukdomar, 171 77 Stockholm
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About me

  • I have a PhD and a Diploma in Clinical Trials and am a certified research nurse, with approximately 30 years of experience in clinical research and clinical trials in healthcare. Over the past 15 years, my work has primarily focused on the planning, coordination and management of academic multicentre stroke trials in Sweden. I also have experience in monitoring.

    I am affiliated with two research groups: Stroke and Neurovascular Diseases.

    My research primarily focuses on the conduct of randomised controlled trials (RCTs), with particular emphasis on patient recruitment, recruitment processes and factors influencing the conduct of clinical trials.

    Doctoral thesis

    I was awarded my PhD in March 2021 for my thesis, Recruitment to multicentre randomised controlled trials in stroke. Lessons learnt from the EFFECTS trial. The thesis was based on the EFFECTS trial, an academically initiated randomised controlled multicentre trial in stroke, in which I worked as Trial Manager.

    I currently work as a Research Coordinator within the Department of Clinical Neuroscience at Danderyd Hospital and am also responsible for the support function at the Clinical Research Centre (KFC). Through these roles, I remain closely involved in clinical research and the practical conduct of clinical trials. My work includes developing structures and processes to support researchers and clinical departments throughout the study lifecycle, from planning and start-up to implementation and completion.

    Future research

    My future research aims to deepen understanding of how clinical trials can be conducted to ensure high quality while remaining feasible in everyday clinical practice. By combining extensive practical experience with scientific expertise, I aim to contribute to the development of effective, patient-centred and sustainable approaches to clinical research. My particular interests include quality, feasibility and the patient perspective.

    Academic qualifications

    PhD, 2021
    Karolinska Institutet

    Thesis: Recruitment to multicentre randomised controlled trials in stroke. Lessons learnt from the EFFECTS trial.

    Diploma in Clinical Trials / Certified Research Nurse, 2009
    Utbildningsrådet

Articles

All other publications

Grants

  • Swedish Research Council
    1 January 2024 - 31 December 2027
    The purpose of the trial is to study the prognostic impact of ECG investigation after stroke or Transient Ischemic Attack (TIA).The aim is to investigate if extended ECG screening after stroke or TIA as compared to standard ECG screening for atrial fibrillation reduces the occurrence of the primary composite endpoint of stroke, death and intracranial bleeding.P: Patients aged ≥70 years and admitted for ischemic stroke/TIA in Swedish stroke units. I: Extended long-term ECG-recording of 14 + 14 days duration using patch ECG, read in a core facility. Oral anticoagulation treatment will be suggested to all cases detected with atrial fibrillation in intervention and control arm unless contraindicated.C: Standard ECG recording of 48 hO: Primary outcome is a composite of stroke, all-cause mortality and intracerebral bleeding. Secondary and exploratory oucomes include the individual components of the primary endpoint, intracranial bleedning, myocardial infarction, major bleeding and pacemaker implantation. Endpoint and majority of baseline data will be collected from Swedish health care registers, mainly Riksstroke but also inpatient, drug prescription and cause of death register. Sample size is estimated at 2700. Pilot study commenced ni 2022, main trial is planned to recruit 2023-2026 and follow-up 2027-2028.Given a positive result, the study will give evidence to an investigation and treatment that will improve prognosis in a large group of patients with very poor prognosis.
  • Swedish Research Council
    1 January 2022 - 31 December 2023

Employments

  • Affiliated to Research, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2024-2027

Degrees and Education

  • Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2021

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