Eric Thelin

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Articles

Article: BIOENGINEERING-BASEL. 2025;12(9):1006
Relationship Between RAP and Multi-Modal Cerebral Physiological Dynamics in Moderate/Severe Acute Traumatic Neural Injury: A CAHR-TBI Multivariate Analysis.
Islam A; Stein KY; Griesdale D; Sekhon M; Raj R; Bernard F; Gallagher C; Thelin EP; Mathieu F; Kramer A; Aries M; Froese L; Zeiler FA
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112:znaf149.002-xi1
ASA score is an independent predictor of 1-year outcome after moderate-to-severe Traumatic Brain Injury
Kiwanuka O; Lassaren P; Fletcher-Sandersjoo A; Tatter C; Tjerkaski J; Nelson DW; Thelin EP
Article: JOURNAL OF NEUROTRAUMA. 2025
Inflammatory Mediators Related to Vascular Dysfunction are Linked to ICP, PRx, and CPP Following Human Severe Traumatic Brain Injury
Smith CA; Lindblad C; Needham E; Beqiri E; Bergstrom S; Smielewski P; Nilsson P; Thelin E; Helmy A
Article: ACTA NEUROCHIRURGICA. 2025;167(1):181
Stockholm Score of Lesion Detection on Computed Tomography following Mild Traumatic Brain Injury (SELECT-TBI) Study: Pilot Analysis and Statistical Analysis Plan
Yang LJ; Tatter C; Fletcher-Sandersjoo A; Froese L; Lassaren P; Tjerkaski J; Bergman EE; Bjorkman FE; Bronge J; Antonsson J; Teromaa K; Nylander M; Ortqvist S; Kylander W; Lindqvist W; Angeby K; Wahlin RR; Thelin EP
Article: ACTA NEUROCHIRURGICA. 2025;167(1):158
Paroxysmal sympathetic hyperactivity risk modeling based on transients in time series describing the autonomic nervous system and cerebral hemodynamics
Najda M; Mataczynski C; Burzynska M; Kasprowicz M; Kedziora J; Hammarlund E; Thelin EP; Uryga A
Article: SENSORS. 2025;25(9):2762
Impact of Temporal Resolution on Autocorrelative Features of Cerebral Physiology from Invasive and Non-Invasive Sensors in Acute Traumatic Neural Injury: Insights from the CAHR-TBI Cohort
Vakitbilir N; Raj R; Griesdale DEG; Sekhon M; Bernard F; Gallagher C; Thelin EP; Froese L; Stein KY; Kramer AH; Aries MJH; Zeiler FA
Article: SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE. 2025;33(1):25
ASA score is an independent predictor of 1-year outcome after moderate-to-severe traumatic brain injury
Kiwanuka O; Lassaren P; Fletcher-Sandersjoo A; Tatter C; Tjerkaski J; Nelson DW; Thelin EP
Article: NEUROSURGERY. 2025;97(2):298-309
Outcomes After Standardized Burr-Hole Surgery for Chronic Subdural Hematomas: A Population-Based Consecutive Cohort Study of 2655 Patients
Buwaider A; Saemundsson B; Nemer E; Anderberg J; Strom I; Wong S-S; Backelin I; Ahlsson K; Stahl M; Thelin EP; Fletcher-Sandersjoo A; Bartek J
Article: JOURNAL OF NEUROTRAUMA. 2024;41(23-24):2545-2553
Volumetric Assessment of Traumatic Intracranial Hematomas: Is ABC/2 Reliable?
Fletcher-Sandersjoo A; Lewen A; Hanell A; Nelson DW; Maegele M; Svensson M; Bellander B-M; Enblad P; Thelin EP; Wettervik TS
Article: ACTA NEUROCHIRURGICA. 2024;166(1):385
Anticoagulation strategies in patients with coexisting traumatic intracranial hematomas and cerebral venous sinus thrombosis: an observational cohort study
Antonsson J; Tatter C; Agren A; Alpkvist P; Thelin EP; Fletcher-Sandersjoo A
Article: ACTA NEUROCHIRURGICA. 2024;166(1):363
ASA-score is associated with 90-day mortality after complicated mild traumatic brain injury - a retrospective cohort study
Kiwanuka O; Lassaren P; Hanell A; Bostroem L; Thelin EP
Article: CRITICAL CARE. 2024;28(1):294
Cerebral physiologic insult burden in acute traumatic neural injury: a Canadian High Resolution-TBI (CAHR-TBI) descriptive analysis
Stein KY; Gomez A; Griesdale D; Sekhon M; Bernard F; Gallagher C; Thelin EP; Raj R; Aries M; Froese L; Kramer A; Zeiler FA
Article: CRITICAL CARE. 2024;28(1):256
Critical thresholds of long-pressure reactivity index and impact of intracranial pressure monitoring methods in traumatic brain injury
Hong E; Froese L; Ponten E; Fletcher-Sandersjoo A; Tatter C; Hammarlund E; Akerlund CAI; Tjerkaski J; Alpkvist P; Bartek Jr J; Raj R; Lindblad C; Nelson DW; Zeiler FA; Thelin EP
Article: JOURNAL OF NEUROTRAUMA. 2024;41(13-14):1550-1564
Characterizing Diffusion from Microdialysis Catheters in the Human Brain: A Magnetic Resonance Imaging Study With Gadobutrol
Stovell M; Ruetten P; Tozer D; Launey Y; Zimphango C; Thelin E; Lupson V; Giorgi-Coll S; Carpenter TA; Mada M; Jalloh I; Helmy A; Wilson M; Graves M; Menon D; Carpenter K; Hutchinson P
Journal article: CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES. 2024;51(s1):s44
P.104 Prognostic value of NIRS regional oxygen saturation based cerebrovascular reactivity in TBI: a Canadian high resolution traumatic brain injury (CAHR-TBI) cohort study
Gomez A; Froese L; Griesdale D; Thelin E; Raj R; van Iperenburg L; Tas J; Aries M; Stein K; Gallagher C; Bernard F; Kramer A; Zeiler F
Journal article: NEUROSURGERY. 2024;70(Supplement_1):24
120 Outcome Related Thresholds of Near Infrared Spectroscopy Based Cerebrovascular Reactivity Metrics in Moderate Severe TBI: A Canadian High Resolution-TBI (CAHR-TBI) Cohort Study
Gomez AT; Tas J; Aries M; Griesdale D; Froese L; Thelin E; Raj R; Gallagher CN; Bernard F; Kramer AH; Zeiler F
Article: JOURNAL OF NEUROTRAUMA. 2024;41(7-8):910-923
Intracranial Pressure-Derived Cerebrovascular Reactivity Indices and Their Critical Thresholds: A Canadian High Resolution-Traumatic Brain Injury Validation Study
Stein KY; Froese L; Sekhon M; Griesdale D; Thelin EP; Raj R; Tas J; Aries M; Gallagher C; Bernard F; Gomez A; Kramer AH; Zeiler FA
Article: CRITICAL CARE. 2024;28(1):78
Prognostic value of near-infrared spectroscopy regional oxygen saturation and cerebrovascular reactivity index in acute traumatic neural injury: a CAnadian High-Resolution Traumatic Brain Injury (CAHR-TBI) Cohort Study
Gomez A; Froese L; Griesdale D; Thelin EP; Raj R; van Iperenburg L; Tas J; Aries M; Stein KY; Gallagher C; Bernard F; Kramer AH; Zeiler FA
Article: HEALTH TECHNOLOGY ASSESSMENT. 2024;28(12):1-122
A randomised, double blind, placebo-controlled trial of a two-week course of dexamethasone for adult patients with a symptomatic Chronic Subdural Haematoma (Dex-CSDH trial)
Hutchinson PJ; Edlmann E; Hanrahan JG; Bulters D; Zolnourian A; Holton P; Suttner N; Agyemang K; Thomson S; Anderson IA; Al-Tamimi Y; Henderson D; Whitfield P; Gherle M; Brennan PM; Allison A; Thelin EP; Tarantino S; Pantaleo B; Caldwell K; Davis-Wilkie C; Mee H; Warburton EA; Barton G; Chari A; Marcus HJ; Pyne S; King AT; Belli A; Myint PK; Wilkinson I; Santarius T; Turner C; Bond S; Kolias AG
Article: JOURNAL OF NEUROTRAUMA. 2024;41(5-6):705-713
Absolute Contusion Expansion Is Superior to Relative Expansion in Predicting Traumatic Brain Injury Outcomes: A Multi-Center Observational Cohort Study
Fletcher-Sandersjoo A; Wettervik TS; Tatter C; Tjerkaski J; Nelson DW; Maegele M; Svensson M; Lewen A; Enblad P; Bellander B-M; Thelin EP
Article: NEURON. 2023;111(23):3745-3764.e7
Molecular anatomy of adult mouse leptomeninges
Pietila R; Del Gaudio F; He L; Vazquez-Liebanas E; Vanlandewijck M; Muhl L; Mocci G; Bjornholm KD; Lindblad C; Fletcher-Sandersjoo A; Svensson M; Thelin EP; Liu J; van Voorden AJ; Torres M; Antila S; Xin L; Karlstrom H; Storm-Mathisen J; Bergersen LH; Moggio A; Hansson EM; Ulvmar MH; Nilsson P; Makinen T; Mae MA; Alitalo K; Proulx ST; Engelhardt B; McDonald DM; Lendahl U; Andrae J; Betsholtz C
Article: LAKARTIDNINGEN. 2023;120:23122
[Mild traumatic brain injuries].
Vesterlund R; Thelin E; Rubenson Wahlin R; Jin Yang L
Article: SCIENTIFIC REPORTS. 2023;13(1):19249
Predictors of intracranial hemorrhage in neonatal patients on extracorporeal membrane oxygenation
Wood S; Iacobelli R; Kopfer S; Lindblad C; Thelin EP; Fletcher-Sandersjoo A; Broman LM
Journal article: PLOS MEDICINE. 2023;20(11):e1004320
Evaluation of novel computerized tomography scoring systems in human traumatic brain injury: An observational, multicenter study (vol 14, e1002368, 2017)
Thelin EP; Nelson DW; Vehvilainen J; Nystrom H; Kivisaari R; Siironen J
Article: JOURNAL OF NEUROTRAUMA. 2023;40(19-20):2164-2173
Modeling the Inflammatory Response of Traumatic Brain Injury Using Human Induced Pluripotent Stem Cell Derived Microglia
Alam A; Singh T; Kayhanian S; Tjerkaski J; Garcia NM; Carpenter KLH; Patani R; Lindblad C; Thelin EPP; Syed YA; Helmy A
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2023;43(10):1685-1701
High-physiological and supra-physiological 1,2-¹³C₂ glucose focal supplementation to the traumatised human brain
Stovell MG; Howe DJ; Thelin EP; Jalloh I; Helmy A; Guilfoyle MR; Grice P; Mason A; Giorgi-Coll S; Gallagher CN; Murphy MP; Menon DK; Carpenter TA; Hutchinson PJ; Carpenter KLH
Article: BIOENGINEERING-BASEL. 2023;10(10):1124
Temporal Statistical Relationship between Regional Cerebral Oxygen Saturation (rSO₂) and Brain Tissue Oxygen Tension (PbtO₂) in Moderate-to-Severe Traumatic Brain Injury: A Canadian High Resolution-TBI (CAHR-TBI) Cohort Study
Gomez A; Griesdale D; Froese L; Yang E; Thelin EP; Raj R; Aries M; Gallagher C; Bernard F; Kramer AH; Zeiler FA
Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2023;11(1):54
The impact of sedative and vasopressor agents on cerebrovascular reactivity in severe traumatic brain injury
Froese L; Hammarlund E; Akerlund CAI; Tjerkaski J; Hong E; Lindblad C; Nelson DW; Thelin EP; Zeiler FA
Article: JOURNAL OF NEUROTRAUMA. 2023;40(15-16):1762-1778
Optimizing Choice and Timing of Behavioral Outcome Tests after Repetitive Mild Traumatic Brain Injury: A Machine Learning-Based Approach on Multiple Pre-Clinical Experiments
Lassaren P; Conley G; Boucher ML; Conley AN; Morriss NJ; Qiu J; Mannix RC; Thelin EP
Article: JOURNAL OF INFLAMMATION-LONDON. 2023;20(1):22
Stem cell-derived brainstem mouse astrocytes obtain a neurotoxic phenotype in vitro upon neuroinflammation
Lindblad C; Neumann S; Kolbeinsdottir S; Zachariadis V; Thelin EP; Enge M; Thams S; Brundin L; Svensson M
Article: JOURNAL OF NEUROTRAUMA. 2023;40(11-12):1098-1111
Impact of Chronological Age and Biological Sex on Cerebrovascular Reactivity in Moderate/Severe Traumatic Brain Injury: A CAnadian High-Resolution Traumatic Brain Injury (CAHR-TBI) Study
Batson C; Froese L; Sekhon M; Griesdale D; Gomez A; Thelin EP; Raj R; Aries M; Gallagher C; Bernard F; Kramer AH; Zeiler FA
Article: NEUROTRAUMA REPORTS. 2023;4(1):307-317
Cerebrovascular Reactivity Is Not Associated With Therapeutic Intensity in Adult Traumatic Brain Injury: A Validation Study
Froese L; Gomez A; Sainbhi AS; Vakitbilir N; Marquez I; Amenta F; Park K; Stein KY; Thelin EP; Zeiler FA
Article: NEUROTRAUMA REPORTS. 2023;4(1):107-117
Time-Dependent Changes in the Biofluid Levels of Neural Injury Markers in Severe Traumatic Brain Injury Patients-Cerebrospinal Fluid and Cerebral Microdialysates: A Longitudinal Prospective Pilot Study
Lin I-H; Kamnaksh A; Aniceto R; McCullough J; Bekdash R; Eklund M; Ghatan PH; Risling M; Svensson M; Bellander B-M; Nelson DWW; Thelin EP; Agoston DVV
Article: SCIENTIFIC REPORTS. 2023;13(1):2986
Long-term health-related quality of life after trauma with and without traumatic brain injury: a prospective cohort study
Kiwanuka O; Lassaren P; Thelin EP; Hanell A; Sandblom G; Fagerdahl A; Bostrom L
Article: NEUROCRITICAL CARE. 2023;38(1):60-70
Time Course and Clinical Significance of Hematoma Expansion in Moderate-to-Severe Traumatic Brain Injury: An Observational Cohort Study
Fletcher-Sandersjoo A; Tatter C; Tjerkaski J; Bartek JJ; Maegele M; Nelson DW; Svensson M; Thelin EP; Bellander B-M
Journal article: BRAIN AND SPINE. 2023;3:101962
Global trends of publications on machine learning and neurosurgery
Lassarén P; Thelin EP; Bartek J
Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2022;10(1):54
Cerebrovascular pressure reactivity and brain tissue oxygen monitoring provide complementary information regarding the lower and upper limits of cerebral blood flow control in traumatic brain injury: a CAnadian High Resolution-TBI (CAHR-TBI) cohort study
Gomez A; Sekhon M; Griesdale D; Froese L; Yang E; Thelin EP; Raj R; Aries M; Gallagher C; Bernard F; Kramer AH; Zeiler FA
Article: SCIENTIFIC REPORTS. 2022;12(1):17932
Incidence and predictors of brain infarction in neonatal patients on extracorporeal membrane oxygenation: an observational cohort study
Kopfer S; Iacobelli R; Wood S; Lindblad C; Thelin EP; Fletcher-Sandersjoo A; Broman LM
Article: LAKARTIDNINGEN. 2022;119:22007
ABC om Handläggning av patienter med kroniskt subduralhematom.
Fletcher-Sandersjöö A; Skyrman S; Thelin E; Bartek J
Article: FRONTIERS IN NEUROLOGY. 2022;13:952308
Dexamethasone reduces vascular endothelial growth factor in comparison to placebo in post-operative chronic subdural hematoma samples: A target for future drug therapy?
Edlmann E; Giorgi-Coll S; Thelin EP; Hutchinson PJ; Carpenter KLH
Article: BMJ OPEN. 2022;12(9):e060679
Stockholm score of lesion detection on computed tomography following mild traumatic brain injury (SELECT-TBI): study protocol for a multicentre, retrospective, observational cohort study
Fletcher-Sandersjoo A; Tatter C; Yang L; Ponten E; Boman M; Lassaren P; Forsberg S; Gronlund I; Tidehag V; Rubenson-Wahlin R; Strommer L; Westberg K; Angeby K; Djarv T; Lundblad O; Bartek JJ; Thelin EP
Article: FRONTIERS IN PEDIATRICS. 2022;10:921444
The cerebrospinal fluid proteome of preterm infants predicts neurodevelopmental outcome
Leifsdottir K; Jost K; Siljehav V; Thelin EP; Lassaren P; Nilsson P; Haraldsson A; Eksborg S; Herlenius E
Article: NPJ DIGITAL MEDICINE. 2022;5(1):96
Dynamic prediction of mortality after traumatic brain injury using a machine learning algorithm
Raj R; Wennervirta JM; Tjerkaski J; Luoto TM; Posti JP; Nelson DW; Takala R; Bendel S; Thelin EP; Luostarinen T; Korja M
Article: ACTA PAEDIATRICA. 2022;111(5):961-970
Proteomic profiles in cerebrospinal fluid predicted death and disability in term infants with perinatal asphyxia: A pilot study
Leifsdottir K; Thelin EP; Lassaren P; Siljehav V; Nilsson P; Eksborg S; Herlenius E
Article: BRAIN. 2022;145(2):481-489
Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis
Taha DM; Clarke BE; Hall CE; Tyzack GE; Ziff OJ; Greensmith L; Kalmar B; Ahmed M; Alam A; Thelin EP; Garcia NM; Helmy A; Sibley CR; Patani R
Article: SEMINARS IN THROMBOSIS AND HEMOSTASIS. 2022;48(03):301-308
Clinical Significance of Vascular Occlusive Events following Moderate-to-Severe Traumatic Brain Injury: An Observational Cohort Study
Fletcher-Sandersjoo A; Tatter C; Tjerkaski J; Bartek Jr J; Svensson M; Thelin EP; Bellander B-M
Article: NEUROIMAGE: REPORTS. 2022;2(1):100079
Meso-scale network analysis of resting state-fMRI brain network connectivity performs poorly as a prognostic tool in critically ill traumatic brain injury patients.
Tjerkaski J; Thompson WH; Bellander B-M; Thelin EP; Fransson P
Article: ARCHIVES OF CLINICAL NEUROPSYCHOLOGY. 2022;37(2):531-543
Monthlong Intubated Patient with Life-Threatening COVID-19 and Cerebral Microbleeds Suffers Only Mild Cognitive Sequelae at 8-Month Follow-up: A Case Report
Backman L; Moller MC; Thelin EP; Dahlgren D; Deboussard C; Ostlund G; Lindau M
Article: JOURNAL OF NEUROTRAUMA. 2022;39(1-2):58-66
Extended Analysis of Axonal Injuries Detected Using Magnetic Resonance Imaging in Critically Ill Traumatic Brain Injury Patients
Tjerkaski J; Nystrom H; Raj R; Lindblad C; Bellander B-M; Nelson DW; Thelin EP
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2022;42(1):39-55
Focally administered succinate improves cerebral metabolism in traumatic brain injury patients with mitochondrial dysfunction
Khellaf A; Garcia NM; Tajsic T; Alam A; Stovell MG; Killen MJ; Howe DJ; Guilfoyle MR; Jalloh I; Timofeev I; Murphy MP; Carpenter TA; Menon DK; Ercole A; Hutchinson PJ; Carpenter KLH; Thelin EP; Helmy A
Article: JOURNAL OF NEUROINFLAMMATION. 2021;18(1):221
Systemic inflammation alters the neuroinflammatory response: a prospective clinical trial in traumatic brain injury
Lassaren P; Lindblad C; Frostell A; Carpenter KLH; Guilfoyle MR; Hutchinson PJA; Helmy A; Thelin EP
Article: JOURNAL OF IMMUNOLOGY. 2021;207(1):90-100
Complex Autoantibody Responses Occur following Moderate to Severe Traumatic Brain Injury
Needham EJ; Stoevesandt O; Thelin EP; Zetterberg H; Zanier ER; Al Nimer F; Ashton NJ; Outtrim JG; Newcombe VFJ; Mousa HS; Simren J; Blennow K; Yang Z; Hutchinson PJ; Piehl F; Helmy AE; Taussig MJ; Wang KKW; Jones JL; Menon DK; Coles AJ
Article: CRITICAL CARE. 2021;25(1):103
Fluid proteomics of CSF and serum reveal important neuroinflammatory proteins in blood-brain barrier disruption and outcome prediction following severe traumatic brain injury: a prospective, observational study
Lindblad C; Pin E; Just D; Al Nimer F; Nilsson P; Bellander B-M; Svensson M; Piehl F; Thelin EP
Article: SCIENTIFIC REPORTS. 2021;11(1):3809
Predictors of brain infarction in adult patients on extracorporeal membrane oxygenation: an observational cohort study
Iacobelli R; Fletcher-Sandersjoo A; Lindblad C; Keselman B; Thelin EP; Broman LM
Article: FRONTIERS IN NEUROLOGY. 2021;11:610192
Delayed Neurosurgical Intervention in Traumatic Brain Injury Patients Referred From Primary Hospitals Is Not Associated With an Unfavorable Outcome
Grevfors N; Lindblad C; Nelson DW; Svensson M; Thelin EP; Rubenson Wahlin R
Article: CLINICA CHIMICA ACTA. 2021;512:74-83
Cerebrospinal fluid brevican and neurocan fragment patterns in human traumatic brain injury
Minta K; Brinkmalm G; Thelin EP; Al Nimer F; Piehl F; Tullberg M; Jeppsson A; Portelius E; Zetterberg H; Blennow K; Andreasson U
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2020;383(27):2616-2627
Trial of Dexamethasone for Chronic Subdural Hematoma
Hutchinson PJ; Edlmann E; Bulters D; Zolnourian A; Holton P; Suttner N; Agyemang K; Thomson S; Anderson IA; Al-Tamimi YZ; Henderson D; Whitfield PC; Gherle M; Brennan PM; Allison A; Thelin EP; Tarantino S; Pantaleo B; Caldwell K; Davis-Wilkie C; Mee H; Warburton EA; Barton G; Chari A; Marcus HJ; King AT; Belli A; Myint PK; Wilkinson I; Santarius T; Turner C; Bond S; Kolias AG
Article: SCIENTIFIC REPORTS. 2020;10(1):18075
Dynamics of cerebrospinal fluid levels of matrix metalloproteinases in human traumatic brain injury
Minta K; Brinkmalm G; Al Nimer F; Thelin EP; Piehl F; Tullberg M; Jeppsson A; Portelius E; Zetterberg H; Blennow K; Andreasson U
Journal article: BRAIN. 2020;143(10):e85
Human stem cell-derived astrocytes exhibit region-specific heterogeneity in their secretory profiles
Clarke BE; Taha DM; Ziff OJ; Alam A; Thelin EP; Garcia NM; Helmy A; Patani R
Article: JOURNAL OF CLINICAL MONITORING AND COMPUTING. 2020;34(5):971-994
Comparison of high versus low frequency cerebral physiology for cerebrovascular reactivity assessment in traumatic brain injury: a multi-center pilot study
Thelin EP; Raj R; Bellander B-M; Nelson D; Piippo-Karjalainen A; Siironen J; Tanskanen P; Hawryluk G; Hasen M; Unger B; Zeiler FA
Article: JOURNAL OF NEUROTRAUMA. 2020;37(12):1381-1391
Influence of Blood-Brain Barrier Integrity on Brain Protein Biomarker Clearance in Severe Traumatic Brain Injury: A Longitudinal Prospective Study
Lindblad C; Nelson DW; Zeiler FA; Ercole A; Ghatan PH; von Horn H; Risling M; Svensson M; Agoston DV; Bellander B-M; Thelin EP
Article: JOURNAL OF NEUROTRAUMA. 2020;37(10):1233-1241
Association between Cerebrovascular Reactivity Monitoring and Mortality Is Preserved When Adjusting for Baseline Admission Characteristics in Adult Traumatic Brain Injury: A CENTER-TBI Study
Zeiler FA; Ercole A; Beqiri E; Cabeleira M; Thelin EP; Stocchetti N; Steyerberg EW; Maas AIR; Menon DK; Czosnyka M; Smielewski P; Anke A; Beer R; Helbok R; Bellander B-M; Nelson D; Buki A; Chevallard G; Chieregato A; Citerio G; Czeiter E; Depreitere B; Eapen G; Frisvold S; Jankowski S; Kondziella D; Koskinen L-O; Meyfroidt G; Moeller K; Piippo-Karjalainen A; Raj R; Radoi A; Sahuquillo J; Ragauskas A; Rocka S; Rhodes J; Rossaint R; Stevanovic A; Sakowitz O; Sundstrom N; Takala R; Tamosuitis T; Tenovuo O; Vajkoczy P; Vargiolu A; Vilcinis R; Wolf S; Younsi A
Article: LAKARTIDNINGEN. 2020;117:FSWM
[Better guidelines needed for mild traumatic brain injury in the primary care setting].
Kreibom S; Bartek J; Thelin E; Bellander B-M; Deboussar C
Journal article: JOURNAL OF INTENSIVE CARE. 2020;8(1):2
Predictors of intracranial hemorrhage in adult patients on extracorporeal membrane oxygenation: an observational cohort study (vol 5, 27, 2017)
Fletcher-Sandersjoo A; Bartek JJ; Thelin EP; Eriksson A; Elmi-Terander A; Broman M; Bellander B-M
Article: JOURNAL OF NEUROTRAUMA. 2020;37(1):93-105
Delineating Astrocytic Cytokine Responses in a Human Stem Cell Model of Neural Trauma
Thelin EP; Hall CE; Tyzack GE; Frostell A; Giorgi-Coll S; Alam A; Carpenter KLH; Mitchell J; Tajsic T; Hutchinson PJ; Patani R; Helmy A
Article: JOURNAL OF NEUROTRAUMA. 2020;37(1):106-114
Dextran 500 Improves Recovery of Inflammatory Markers: An In Vitro Microdialysis Study
Giorgi-Coll S; Thelin EP; Lindblad C; Tajsic T; Carpenter KLH; Hutchinson PJA; Helmy A
Article: TRIALS. 2019;20(1):698
Statistical analysis plan for the Dex-CSDH trial: a randomised, double-blind, placebo-controlled trial of a 2-week course of dexamethasone for adult patients with a symptomatic chronic subdural haematoma
Allison A; Edlmann E; Kolias AG; Davis-Wilkie C; Mee H; Thelin EP; Turner C; Hutchinson PJ; Bond S
Article: ACTA NEUROCHIRURGICA. 2019;161(12):2467-2478
Prognostic performance of computerized tomography scoring systems in civilian penetrating traumatic brain injury: an observational study
Lindfors M; Lindblad C; Nelson DW; Bellander B-M; Siironen J; Raj R; Thelin EP
Article: JOURNAL OF NEUROTRAUMA. 2019;36(20):2850-2862
A Serum Protein Biomarker Panel Improves Outcome Prediction in Human Traumatic Brain Injury
Thelin E; Al Nimer F; Frostell A; Zetterberg H; Blennow K; Nystrom H; Svensson M; Bellander B-M; Piehl F; Nelson DW
Article: CLINICAL CHEMISTRY AND LABORATORY MEDICINE. 2019;57(10):1565-1573
Dynamics of extracellular matrix proteins in cerebrospinal fluid and serum and their relation to clinical outcome in human traumatic brain injury
Minta K; Cullen NC; Al Nimer F; Thelin EP; Piehl F; Clarin M; Tullberg M; Jeppsson A; Portelius E; Zetterberg H; Blennow K; Andreasson U
Article: NEUROCRITICAL CARE. 2019;30(3):590-600
The Role of Glycerol-Containing Drugs in Cerebral Microdialysis: A Retrospective Study on the Effects of Intravenously Administered Glycerol
Forssten MP; Thelin EP; Nelson DW; Bellander B-M
Journal article: JOURNAL OF INTERNAL MEDICINE. 2019;285(6):591-593
Head trauma in sports and risk for dementia
Winblad B; Ankarcrona M; Johansson G; Novak P; Thelin EP; Zetterberg H; Blennow K
Article: FRONTIERS IN NEUROLOGY. 2019;10:512
Serial S100B Sampling Detects Intracranial Lesion Development in Patients on Extracorporeal Membrane Oxygenation
Fletcher-Sandersjoo A; Lindblad C; Thelin EP; Bartek JJ; Sallisalmi M; Elmi-Terander A; Svensson M; Bellander B-M; Broman LM
Article: SCIENTIFIC REPORTS. 2019;9(1):5885
Dex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma: report of the internal pilot phase
Edlmann E; Thelin EP; Caldwell K; Turner C; Whitfield P; Bulters D; Holton P; Suttner N; Owusu-Agyemang K; Al-Tamimi YZ; Gatt D; Thomson S; Anderson IA; Richards O; Gherle M; Toman E; Nandi D; Kane P; Pantaleo B; Davis-Wilkie C; Tarantino S; Barton G; Marcus HJ; Chari A; Belli A; Bond S; Gafoor R; Dawson S; Whitehead L; Brennan P; Wilkinson I; Kolias AG; Hutchinson PJA; Badran K; Coulter I; Gallagher MJ; Hogg FRA; Pringle C; Razak A; Soleiman H; Piper R; Vintu M; Wahba A; Wiggins A; Yakoub KM; Zaben M; Zolnourian A; Bodkin P; Cirstea E; Critchley G; Eglinton C; Finlay L; Georgieva D; Gurusinghe N; Haliasos N; Holliman D; Hossain-Ibrahim K; Hussain M; Kandasamy J; Kambafwile M; Nannapaneni R; de Gordoa LO-R; Papadopoulos MC; Paraskevopoulos D; Patel J; Prasad KSM; Tzerakis N
Journal article: TRIALS. 2019;20(1):175
Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial (vol 19, 670, 2018)
Kolias AG; Edlmann E; Thelin EP; Bulters D; Holton P; Suttner N; Owusu-Agyemang K; Al-Tamimi YZ; Gatt D; Thomson S; Anderson IA; Richards O; Whitfield P; Gherle M; Caldwell K; Davis-Wilkie C; Tarantino S; Barton G; Marcus HJ; Chari A; Brennan P; Belli A; Bond S; Turner C; Whitehead L; Wilkinson I; Hutchinson PJ
Article: TRIALS. 2018;19(1):670
Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial
Kolias AG; Edlmann E; Thelin EP; Bulters D; Holton P; Suttner N; Owusu-Agyemang K; Al-Tamimi YZ; Gatt D; Thomson S; Anderson IA; Richards O; Whitfield P; Gherle M; Caldwell K; Davis-Wilkie C; Tarantino S; Barton G; Marcus HJ; Chari A; Brennan P; Belli A; Bond S; Turner C; Whitehead L; Wilkinson I; Hutchinson PJ
Article: SCIENTIFIC REPORTS. 2018;8(1):11140
The effect of succinate on brain NADH/NAD⁺ redox state and high energy phosphate metabolism in acute traumatic brain injury
Stovell MG; Mada MO; Helmy A; Carpenter TA; Thelin EP; Yan J-L; Guilfoyle MR; Jalloh I; Howe DJ; Grice P; Mason A; Giorgi-Coll S; Gallagher CN; Murphy MP; Menon DK; Hutchinson PJ; Carpenter KLH
Article: JOURNAL OF NEUROTRAUMA. 2018;35(14):1569-1577
Intracranial and Extracranial Injury Burden as Drivers of Impaired Cerebrovascular Reactivity in Traumatic Brain Injury
Zeiler FA; Donnelly J; Nourallah B; Thelin EP; Calviello L; Smielewski P; Czosnyka M; Ercole A; Menon DK
Article: FRONTIERS IN NEUROLOGY. 2018;9:194
Prehospital Intubation and Outcome in Traumatic Brain Injury-Assessing Intervention Efficacy in a Modern Trauma Cohort
Wahlin RR; Nelson DW; Bellander B-M; Svensson M; Helmy A; Thelin EP
Journal article: FRONTIERS IN NEUROLOGY. 2018;9:193
Editorial: Monitoring Pathophysiology in the injured Brain
Thelin EP; Helmy A; Nelson DW; Marklund N
Article: BEHAVIOURAL BRAIN RESEARCH. 2018;340:71-80
Protein profiling in serum after traumatic brain injury in rats reveals potential injury markers
Thelin EP; Just D; Frostell A; Haggmark-Manberg A; Risling M; Svensson M; Nilsson P; Bellander B-M
Article: FRONTIERS IN NEUROLOGY. 2018;9:15
Assessment of Platelet function in Traumatic Brain Injury-A Retrospective Observational Study in the Neuro-Critical Care Setting
Lindblad C; Thelin EP; Nekludov M; Frostell A; Nelson DW; Svensson M; Bellander B-M
Article: JOURNAL OF NEUROTRAUMA. 2018;35(2):341-352
Elucidating Pro-inflammatory Cytokine Responses after Traumatic Brain Injury in a Human Stem Cell Model
Thelin EP; Hall CE; Gupta K; Carpenter KLH; Chandran S; Hutchinson PJ; Patani R; Helmy A
Article: PLOS ONE. 2017;12(12):e0190365
Management of intracranial hemorrhage in adult patients on extracorporeal membrane oxygenation (ECMO): An observational cohort study
Fletcher-Sandersjoo A; Thelin EP; Bartek JJ; Elmi-Terander A; Broman M; Bellander B-M
Article: EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY. 2017;43(6):783-789
β-Blocker after severe traumatic brain injury is associated with better long-term functional outcome: a matched case control study
Ahl R; Thelin EP; Sjolin G; Bellander B-M; Riddez L; Talving P; Mohseni S
Article: NEUROSURGERY. 2017;81(4):650-658
Health-Related Quality of Life Dynamics 2 Years Following Aneurysmal Subarachnoid Hemorrhage: A Prospective Cohort Study Using EQ-5D
von Vogelsang A-C; Thelin EP; Hakim R; Svensson M
Article: PLOS MEDICINE. 2017;14(8):e1002368
Evaluation of novel computerized tomography scoring systems in human traumatic brain injury: An observational, multicenter study
Thelin EP; Nelson DW; Vehvilainen J; Nystrom H; Kivisaari R; Siironen J; Svensson M; Skrifvars MB; Bellander B-M; Raj R
Article: JOURNAL OF INTENSIVE CARE. 2017;5:27
Predictors of intracranial hemorrhage in adult patients on extracorporeal membrane oxygenation: an observational cohort study
Sandersjoo AF; Bartek JJ; Thelin EP; Eriksson A; Elmi-Terander A; Broman M; Bellander B-M
Article: FRONTIERS IN NEUROLOGY. 2016;7:238
A Review of the Segmental Diameter of the Healthy Human Spinal Cord
Frostell A; Hakim R; Thelin EP; Mattsson P; Svensson M
Journal article: CRITICAL CARE. 2016;20(1):376
The utility of biomarkers in traumatic brain injury clinical management
Rodriguez-Rodriguez A; Jose Egea-Guerrero J
Article: EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY. 2016;42(5):617-625
Assessing bicycle-related trauma using the biomarker S100B reveals a correlation with total injury severity
Thelin EP; Zibung E; Riddez L; Nordenvall C
Article: CRITICAL CARE. 2016;20:285
Utility of neuron-specific enolase in traumatic brain injury; relations to S100B levels, outcome, and extracranial injury severity
Thelin EP; Jeppsson E; Frostell A; Svensson M; Mondello S; Bellander B-M; Nelson DW
Article: BRAIN INJURY. 2016;30(10):1256-1260
Positive blood alcohol level in severe traumatic brain injury is associated with better long-term functional outcome
Mohseni S; Bellander B-M; Riddez L; Talving P; Thelin EP
Article: BMC NEUROLOGY. 2016;16:93
Kinetic modelling of serum S100b after traumatic brain injury
Ercole A; Thelin EP; Holst A; Bellander BM; Nelson DW
Article: FRONTIERS IN NEUROLOGY. 2016;7:23
Lesion Size Is Exacerbated in Hypoxic Rats Whereas Hypoxia-Inducible Factor-1 Alpha and Vascular Endothelial Growth Factor Increase in Injured Normoxic Rats: A Prospective Cohort Study of Secondary Hypoxia in Focal Traumatic Brain Injury
Thelin EP; Frostell A; Mulder J; Mitsios N; Damberg P; Aski SN; Risling M; Svensson M; Morganti-Kossmann MC; Bellander B-M
Article: NEUROIMAGE-CLINICAL. 2016;12:1004-1012
Functional resting-state fMRI connectivity correlates with serum levels of the S100B protein in the acute phase of traumatic brain injury
Thompson WH; Thelin EP; Lilja A; Bellander B-M; Fransson P
Article: PLOS ONE. 2016;11(3):e0152268
Neuron-Specific Enolase Is Correlated to Compromised Cerebral Metabolism in Patients Suffering from Acute Bacterial Meningitis; An Observational Cohort Study.
Bartek J; Thelin EP; Ghatan PH; Glimaker M; Bellander B-M
Article: METHODS IN MOLECULAR BIOLOGY. 2016;1462:459-479
Experimental Models Combining Traumatic Brain Injury and Hypoxia.
Thelin EP
Article: WORLD JOURNAL OF SURGERY. 2015;39(8):2076-2083
The Effect of β-blockade on Survival After Isolated Severe Traumatic Brain Injury
Mohseni S; Talving P; Thelin EP; Wallin G; Ljungqvist O; Riddez L
Article: PLOS ONE. 2015;10(7):e0132177
Comparative Assessment of the Prognostic Value of Biomarkers in Traumatic Brain Injury Reveals an Independent Role for Serum Levels of Neurofilament Light
Al Nimer F; Thelin E; Nystrom H; Dring AM; Svenningsson A; Piehl F; Nelson DW; Bellander B-M
Article: FRONTIERS IN NEUROLOGY. 2015;6:62
Biocnemical response to hyperbaric oxygen treatment of a transhemispheric penetrating cerebral gunshot injury
Thelin EP; Bellander B-M; Nekludov M
Article: NEUROCRITICAL CARE. 2014;20(2):217-229
Secondary Peaks of S100B in Serum Relate to Subsequent Radiological Pathology in Traumatic Brain Injury
Thelin EP; Nelson DW; Bellander B-M
Article: FRONTIERS IN NEUROLOGY. 2014;5:159
Microdialysis monitoring of CSF parameters in severe traumatic brain injury patients: a novel approach
Thelin EP; Nelson DW; Ghatan PH; Bellander B-M
Article: JOURNAL OF NEUROTRAUMA. 2013;30(7):519-528
S100B Is an Important Outcome Predictor in Traumatic Brain Injury
Thelin EP; Johannesson L; Nelson D; Bellander B-M
Journal article: FRONTIERS IN NEUROLOGY. 2013;4:26
In response to comments made in "S100B protein and chronic subdural hematoma"
Thelin EP; Persson ME; Bellander B-M
Article: FRONTIERS IN NEUROLOGY. 2012;3:170
Case Report: Extreme Levels of Serum S-100B in a Patient with Chronic Subdural Hematoma.
Persson ME; Thelin EP; Bellander B-M
Journal article: FRONTIERS IN NEUROLOGY. 2010;1
The rise and decline of serum S100B in traumatic brain injury in humans with focus on the temporal profile and correlation to outcome
Eric T
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All other publications

Review: ACTA NEUROCHIRURGICA. 2025;167(1):146
Hemostatic disturbances in traumatic brain injury: from mechanism to management
Fletcher-Sandersjoo A; Sebghati J; Thelin EP
Review: NATURE REVIEWS NEUROLOGY. 2024;20(11):671-684
Fluid biomarkers of chronic traumatic brain injury
Friberg S; Lindblad C; Zeiler FA; Zetterberg H; Granberg T; Svenningsson P; Piehl F; Thelin EP
Review: SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE. 2024;32(1):91
Risk factors for traumatic intracranial hemorrhage in mild traumatic brain injury patients at the emergency department: a systematic review and meta-analysis
Yang LJ; Lassaren P; Londi F; Palazzo L; Fletcher-Sandersjoo A; Angeby K; Thelin EP; Rubenson Wahlin R
Preprint: BIORXIV. 2024
ATF4 orchestrates IL-1α-induced senescence in adult neural stem cells
Neumann S; Thelin EP; Sankavaram SR; Persson S; Fonseca L; Moruzzi N; Iacobaeus E; Bergsland M; Popova E; Bader M; Svensson M; Espinosa A; Covacu R; Brundin L
Conference publication: JOURNAL OF NEUROTRAUMA. 2023;40(15-16):A44
A PREDICTIVE SCORING SYSTEM FOR INTRACRANIAL LESIONS IN MILD TRAUMATIC BRAIN INJURY PATIENTS: PRELIMINARY RESULTS FROM THE STOCKHOLM SCORE OF LESION DETECTION ON COMPUTED TOMOGRAPHY FOLLOWING MILD TRAUMATIC BRAIN INJURY (SELECT-TBI) STUDY
Yang LJ; Fletcher-Sandersjoo A; Lassaren P; Tjerkaski J; Bergman E; Bjorkman F; Bronge J; Antonsson J; Teromaa K; Solodovnykova M; Ortqvist S; Kylander W; Lindqvist W; Wahlin RR; Thelin E
Conference publication: JOURNAL OF NEUROSURGERY. 2023;138(5)
The Relationship Between Cerebral Perfusion Pressure, Brain Tissue Oxygen, and Cerebrovascular Pressure Reactivity: A Canadian High Resolution-Traumatic Brain Injury (CAHR-TBI) Study
Gomez A; Sekhon M; Griesdale D; Froese L; Thelin E; Raj R; Aries M; Gallagher C; Bernard F; Kramer A; Zeiler F
Review: FRONTIERS IN NEUROLOGY. 2023;14:1085540
An overview of clinical cerebral microdialysis in acute brain injury
Stovell MG; Helmy A; Thelin EP; Jalloh I; Hutchinson PJ; Carpenter KLH
Book chapter: BIOMARKERS IN TRAUMA, INJURY AND CRITICAL CARE: BIOMARKERS IN DISEASE: METHODS, DISCOVERIES AND APPLICATIONS. 2023;p. 1047-1069
Cerebrospinal Fluid as a Platform for Biomarker Identification in Traumatic Brain Injury
Thelin EP; Lindblad C
Review: ACTA NEUROCHIRURGICA. 2022;164(12):3091-3100
Current state of high-fidelity multimodal monitoring in traumatic brain injury
Lindblad C; Raj R; Zeiler FA; Thelin EP
Conference publication: JOURNAL OF NEUROTRAUMA. 2022;39(15-16):A23
HEALTH-RELATED QUALITY OF LIFE AFTER TRAUMA WITH OR WITHOUT TBI - A PROSPECTIVE COHORT STUDY
Kiwanuka O; Thelin E; Bellander BM; Fagerdahl AM; Bostrom L
Conference publication: JOURNAL OF NEUROTRAUMA. 2022;39(15-16):A8-A9
CYTOTOXIC BRAIN EDEMA IS ASSOCIATED WITH NEUROINFLAMMATION AND RETRACTION OF PERIVASCULAR AQUAPORIN-4 FOLLOWING EXPERIMENTAL SEVERE TRAUMATIC BRAIN INJURY - A MULTI-MODAL IMAGING STUDY
Lindblad C; Mitsios N; Falk-Delgado A; Mattsson P; Morganti-Kossmann MC; Frostell A; Mulder J; Risling M; Damberg P; Bellander BM; Thelin E; Svensson M
Conference publication: JOURNAL OF NEUROTRAUMA. 2022;39(15-16):A22-A23
OPTIMIZING CHOICE AND TIMING OF BEHAVIORAL OUTCOME TESTS FOLLOWING REPETITIVE MILD TRAUMATIC BRAIN INJURY: A MACHINE LEARNING-BASED APPROACH ON MULTIPLE PRECLINICAL EXPERIMENTS
Lassaren P; Conley G; Boucher M; Conley AN; Qiu J; Mannix RC; Thelin E
Conference publication: JOURNAL OF NEUROTRAUMA. 2022;39(15-16):A10
MULTI-COMPARTMENTAL METABOLIC DYNAMICS FOLLOWING SEVERE TRAUMATIC BRAIN INJURY HIGHLIGHT THE NECESSITY OF FOCAL MONITORING
Hammarlund E; Lindblad C; Akerlund C; Bellander BM; Nelson D; Thelin E
Conference publication: JOURNAL OF NEUROTRAUMA. 2022;39(15-16):A17
ASSOCIATION OF INITIAL TRAUMA CHARACTERISTICS IN SEVERE TRAUMATIC BRAIN INJURY WITH LONG TERM CLINICAL OUTCOMES AND MARKERS OF NEURODEGENERATION AND NEUROINFLAMMATION - A PILOT STUDY
Friberg S; Lindblad C; Zeiler F; Svenningsson P; Granberg T; Piehl F; Thelin E
Book chapter: BIOMARKERS IN TRAUMA, INJURY AND CRITICAL CARE: BIOMARKERS IN DISEASE: METHODS, DISCOVERIES AND APPLICATIONS. 2022;p. 1-24
Cerebrospinal Fluid as a Platform for Biomarker Identification in Traumatic Brain Injury
Thelin EP; Lindblad C
Review: FRONTIERS IN NEUROLOGY. 2021;12:729184
Integrative Neuroinformatics for Precision Prognostication and Personalized Therapeutics in Moderate and Severe Traumatic Brain Injury
Zeiler FA; Iturria-Medina Y; Thelin EP; Gomez A; Shankar JJ; Ko JH; Figley CR; Wright GEB; Anderson CM
Preprint: RESEARCH SQUARE. 2021
Clinical Impact of Hemorrhagic Lesion Progression Following Moderate-to-Severe Traumatic Brain Injury: An Observational Cohort Study
Fletcher-Sandersjöö A; Tatter C; Tjerkaski J; Bartek J; Maegele M; Nelson D; Svensson M; Thelin EP; Bellander B-M
Preprint: RESEARCH SQUARE. 2021
Systemic Inflammation Alters The Neuroinflammatory Response: A Prospective Clinical Trial In Traumatic Brain Injury
Lassarén P; Lindblad C; Frostell A; Carpenter KLH; Guilfoyle M; Hutchinson PJA; Helmy A; Thelin EP
Review: NEUROCRITICAL CARE. 2021;34(2):635-656
Time Course of Hemostatic Disruptions After Traumatic Brain Injury: A Systematic Review of the Literature
Fletcher-Sandersjoo A; Thelin EP; Maegele M; Svensson M; Bellander B-M
Preprint: RESEARCH SQUARE. 2021
RETRACTED: Extended analysis of axonal injuries detected using magnetic resonance imaging and their relation to outcome in critically ill traumatic brain injury patients
Tjerkaski J; Nyström H; Raj R; Lindblad C; Bellander B-M; Nelson DW; Thelin EP
Preprint: RESEARCH SQUARE. 2021
Systemic Inflammation Alters the Neuroinflammatory Response: A Prospective Clinical Trial in Traumatic Brain Injury.
Lassarén P; Lindblad C; Frostell A; Carpenter KL; Guilfoyle MR; Hutchinson PJ; Helmy A; Thelin EP
Preprint: RESEARCH SQUARE. 2021
Fluid Proteomics of CSF and Serum Reveal Important Neuroinflammatory Proteins in Blood-Brain Barrier Disruption and Outcome Prediction following Severe Traumatic Brain Injury: a Prospective, Observational Study
Lindblad C; Pin E; Just D; Nimer FA; Nilsson P; Bellander B-M; Svensson M; Piehl F; Thelin EP
Book chapter: SYSTEMS MEDICINE. 2021;p. 90-96
Inflammation, Neurovascular Clearance and Associated Pathologies: A Translational Review Focusing on Traumatic Brain Injury
Lindblad C; Thelin EP
Review: JOURNAL OF NEUROINFLAMMATION. 2020;17(1):328
Cellular infiltration in traumatic brain injury
Alam A; Thelin EP; Tajsic T; Khan DZ; Khellaf A; Patani R; Helmy A
Preprint: RESEARCH SQUARE. 2020
Fluid Proteomics of CSF and Serum Reveal Important Neuroinflammatory Proteins in Blood-Brain Barrier Disruption and Outcome Prediction Following Severe Traumatic Brain Injury: A Prospective, Observational Study
Lindblad C; Pin E; Just D; Nimer FA; Nilsson P; Bellander B-M; Svensson M; Piehl F; Thelin EP
Review: JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY. 2020;32(4):288-299
Continuous Near-infrared Spectroscopy Monitoring in Adult Traumatic Brain Injury: A Systematic Review
Mathieu F; Khellaf A; Ku JC; Donnelly J; Thelin EP; Zeiler FA
Preprint: MEDRXIV. 2020
Complex Autoantibody Responses Occur Following Moderate to Severe Traumatic Brain Injury
Needham E; Stoevesandt O; Thelin E; Zetterberg H; Zanier E; Nimer FA; Ashton N; Outtrim J; Newcombe VFJ; Mousa H; Simren J; Blennow K; Yang Z Z; Hutchinson P; Piehl F; Helmy A; Taussig M; Wang KKW; Jones J; Menon D; Coles A
Review: ACTA NEUROCHIRURGICA. 2020;162(7):1647-1662
Alternative continuous intracranial pressure-derived cerebrovascular reactivity metrics in traumatic brain injury: a scoping overview
Hasen M; Gomez A; Froese L; Dian J; Raj R; Thelin EP; Zeiler FA
Book chapter: MANAGEMENT OF SEVERE TRAUMATIC BRAIN INJURY. 2020;p. 343-355
Serum Protein Biomarkers in the Management of Severe Traumatic Brain Injury
Thelin EP; Nelson DW; Undén J; Åstrand R; Bellander B-M
Review: JOURNAL OF INTERNAL MEDICINE. 2019;285(6):594-607
Modelling human pathology of traumatic brain injury in animal models
Risling M; Smith D; Stein TD; Thelin EP; Zanier ER; Ankarcrona M; Nilsson P
Review: JOURNAL OF INTERNAL MEDICINE. 2019;285(6):608-623
Treatments and rehabilitation in the acute and chronic state of traumatic brain injury
Marklund N; Bellander B-M; Godbolt AK; Levin H; McCrory P; Thelin EP
Review: JOURNAL OF NEUROTRAUMA. 2019;36(11):1707-1723
Continuous Thermal Diffusion-Based Cerebral Blood Flow Monitoring in Adult Traumatic Brain Injury: A Scoping Systematic Review
Mathieu F; Khellaf A; Thelin EP; Zeiler FA
Conference publication: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2019;90(3):E11
IN VITRO INDUCED CYTOKINE RESPONSE OF ASTROCYTES MODELLING CONDITIONS IN HUMAN TRAUMATIC BRAIN INJURY
Thelin EP; Hall CE; Frostell A; Tajsic T; Carpenter KLH; Hutchinson PJA; Patani R; Helmy A
Conference publication: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2019;90(3):E10-E11
FINAL PHASE OF RECRUITMENT AND STATISTICS ANALYSIS PLAN FOR DEX-CSDH TRIAL
Edlmann E; Kolias A; Thelin E; Gatt D; Al-Tamimi Y; Owusu-Agyemang K; Suttner N; Holton P; Bulters D; Allison A; Bond S; Tarantino S; Davis-Wilkie C; Pantaleo B; Turner C; Hutchinson PJ
Book chapter: ANIMAL MODELS OF NEUROTRAUMA: NEUROMETHODS. 2019;p. 187-198
CNS Regeneration in Nerve Grafts: Practical Aspects of Complete Thoracic Spinal Cord Injury in Rodents
Frostell A; Thelin EP; Mattsson P; Svensson M
Book chapter: ANIMAL MODELS OF NEUROTRAUMA: NEUROMETHODS. 2019;p. 223-242
Secondary Insults in Experimental Traumatic Brain Injury: The Addition of Hypoxia
Lindblad C; Thelin EP
Review: NATURE REVIEWS NEUROLOGY. 2019;15(1):25-39
Genetic drivers of cerebral blood flow dysfunction in TBI: a speculative synthesis
Zeiler FA; Thelin EP; Donnelly J; Stevens AR; Smielewski P; Czosnyka M; Hutchinson PJ; Menon DK
Conference publication: JOURNAL OF NEUROTRAUMA. 2018;35(16):A126-A127
TRAJECTORY CLUSTERING USING LATENT CLASS MODELS FOR UNSUPERVISED TBI BIOMARKER TEMPORAL PHENOTYPE DISCOVER
Ercole A; Lindblad C; Nelson DW; Risling M; Svensson M; Bellander B-M; Thelin EP; Dixit A
Conference publication: JOURNAL OF NEUROTRAUMA. 2018;35(16):A235
INFLUENCE OF BLOOD-BRAIN BARRIER INTEGRITY ON BIOMARKER FLUX BETWEEN DIFFERENT COMPARTMENTS FOLLOWING TRAUMATIC BRAIN INJURY
Lindblad C; Nelson DW; Ercole A; Ghatan PH; Risling M; Svensson M; Agoston DV; Bellander B-M; Thelin EP
Conference publication: JOURNAL OF NEUROTRAUMA. 2018;35(16):A77
INTRACRANIAL VERSUS EXTRACRANIAL CHANGES IN PROTEIN BIOMARKER LEVELS IN EXPERIMENTAL AND CLINICAL TBI STUDIES
Agoston DV; Thelin EP; Bellander B-M; Nelson DW; Ahmed F; Gyorgyi A; Tong L; Kamnaksh A
Conference publication: JOURNAL OF NEUROTRAUMA. 2018;35(16):A255
COGITATE: A FEASIBILITY AND SAFETY STUDY OF TARGETING THE OPTIMAL CEREBRAL PERFUSION PRESSURE AFTER SEVERE TBI
Beqiri V; Donnelly J; Robba C; Cabeleira M; Tas J; Outtrim J; Thelin EP; Kolias A; Lalou A; Liberti A; Turner C; Hutchinson PJA; Menon DK; Smielewski P; Czosnyka M; Meyfroidt G; Depreitere B; Aries MJ; Ercole A
Conference publication: JOURNAL OF NEUROTRAUMA. 2018;35(16):A143
HIGH-PHYSIOLOGICAL AND SUPRA-PHYSIOLOGICAL 1,2-13C2 GLUCOSE SUPPLEMENTATION TO THE TRAUMATISED HUMAN BRAIN
Stovell MG; Howe D; Thelin EP; Helmy A; Jalloh I; Guilfoyle M; Grice P; Mason A; Giorgi-Coll S; Gallagher C; Murphy M; Menon DK; Carpenter AT; Hutchinson PJA; Carpenter KLH
Conference publication: JOURNAL OF NEUROTRAUMA. 2018;35(16):A242-A243
THE EFFECT OF SUCCINATE ON BRAIN NADH/NAD1 REDOX STATE AND HIGH ENERGY PHOSPHATE METABOLISM IN ACUTE TRAUMATIC BRAIN INJURY
Stovell MG; Mada M; Helmy A; Thelin EP; Yan J-L; Guilfoyle M; Jalloh I; Howe D; Grice P; Mason A; Giorgi-Coll S; Gallagher C; Murphy M; Menon DK; Carpenter AT; Hutchinson PJA; Carpenter KLH
Conference publication: JOURNAL OF NEUROTRAUMA. 2018;35(16):A159-A160
IN VITRO INDUCED CYTOKINE RESPONSE OF ASTROCYTES MODELLING CONDITIONS IN HUMAN TRAUMATIC BRAIN INJURY
Thelin EP; Hall CE; Frostell A; Giorgi-Coll S; Carpenter KLH; Tajsic T; Hutchinson PJA; Patani R; Helmy A
Review: FRONTIERS IN NEUROLOGY. 2018;9:548
Incidence, Outcome, and Predictors of Intracranial Hemorrhage in Adult Patients on Extracorporeal Membrane Oxygenation: A Systematic and Narrative Review
Fletcher-Sandersjoo A; Thelin EP; Bartek JJ; Broman M; Sallisalmi M; Elmi-Terander A; Bellander B-M
Review: EXPERT REVIEW OF PROTEOMICS. 2018;15(5):451-461
Extracellular vesicles: pathogenetic, diagnostic and therapeutic value in traumatic brain injury
Mondello S; Thelin EP; Shaw G; Salzet M; Visalli C; Cizkova D; Kobeissy F; Buki A
Review: ACTA NEUROCHIRURGICA. 2017;159(12):2245-2273
A systematic review of cerebral microdialysis and outcomes in TBI: relationships to patient functional outcome, neurophysiologic measures, and tissue outcome
Zeiler FA; Thelin EP; Helmy A; Czosnyka M; Hutchinson PJA; Menon DK
Review: FRONTIERS IN NEUROLOGY. 2017;8:379
Cerebrospinal Fluid and Microdialysis Cytokines in Aneurysmal Subarachnoid Hemorrhage: A Scoping Systematic Review
Zeiler FA; Thelin EP; Czosnyka M; Hutchinson PJ; Menon DK; Helmy A
Review: MINERVA ANESTESIOLOGICA. 2017;83(8):844-857
Cerebral autoregulation monitoring in acute traumatic brain injury: what's the evidence?
Calviello LA; Donnelly J; Zeiler FA; Thelin EP; Smielewski P; Czosnyka M
Review: FRONTIERS IN NEUROLOGY. 2017;8:351
Monitoring the Neuroinflammatory Response Following Acute Brain injury
Thelin EP; Tajsic T; Zeiler FA; Menon DK; Hutchinson PJA; Carpenter KLH; Morganti-Kossmann MC; Helmy A
Review: FRONTIERS IN NEUROLOGY. 2017;8:331
Cerebrospinal Fluid and Microdialysis Cytokines in Severe Traumatic Brain injury: A Scoping Systematic Review
Zeiler FA; Thelin EP; Czosnyka M; Hutchinson PJ; Menon DK; Helmy A
Review: FRONTIERS IN NEUROLOGY. 2017;8:300
Serial Sampling of Serum Protein Biomarkers for Monitoring Human Traumatic Brain injury Dynamics: A Systematic Review
Thelin EP; Zeiler FA; Ercole A; Mondello S; Buki A; Bellander B-M; Helmy A; Menon DK; Nelson DW
Conference publication: JOURNAL OF NEUROTRAUMA. 2017;34(13):A124
PREHOSPITAL ADVANCED AIRWAY MANAGEMENT IN TRAUMATIC BRAIN INJURY AND ITS RELATION TO OUTCOME
Wahlin RR; Nelson DW; Bellander B-M; Svensson M; Thelin E
Review: AAPS JOURNAL. 2017;19(2):367-376
Microdialysis Monitoring in Clinical Traumatic Brain Injury and Its Role in Neuroprotective Drug Development
Thelin EP; Carpenter KLH; Hutchinson PJ; Helmy A
Editorial comment: ACTA NEUROCHIRURGICA. 2017;159(2):235
Progressive hemorrhagic injury in patients with traumatic intracerebral hemorrhage: characteristics, risk factors and impact on management Comments
Thelin E
Review: ACTA NEUROCHIRURGICA. 2017;159(2):209-225
A review of the clinical utility of serum S100B protein levels in the assessment of traumatic brain injury
Thelin EP; Nelson DW; Bellander B-M
Letter: CRITICAL CARE. 2016;20:376
The utility of biomarkers in traumatic brain injury clinical management
Peter Thelin E; Jeppsson E; Bellander B-M; Nelson DW
Conference publication: JOURNAL OF NEUROTRAUMA. 2016;33(3):A7
HYPOXIA FOLLOWING TRAUMATIC BRAIN INJURY EXACERBATES LESION SIZE WHEREAS HYPOXIA-INDUCIBLE FACTOR 1 ALPHA AND VASCULAR ENDOTHELIAL GROWTH FACTOR INCREASE IN NORMOXIC RATS
Thelin EP; Frostell A; Mulder J; Mitsios N; Damberg P; Nikkhou-Aski S; Risling M; Svensson M; Morganti-Kossmann MC; Bellander BM
Conference publication: JOURNAL OF NEUROTRAUMA. 2016;33(3):A22
BIOMARKER CHANGES IN VARIOUS FLUID COMPARTMENTS AFTER TRAUMATIC BRAIN INJURY; TEMPORAL CONSIDERATIONS AND THE INVOLVEMENT OF THE GLYMPHATIC SYSTEM
Agoston DV; Kamnaksh A; Olson J; Nagarai N; Mann M; Risling M; Thelin E; Bellander B-M
Conference publication: JOURNAL OF NEUROTRAUMA. 2016;33(3):A39
BAYESIAN MODEL OF TRAUMATIC BRAIN INJURY BIOMARKER KINETICS
Ercole A; Thelin E; Holst A; Bellander B; Nelson D
Conference publication: JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. 2015;221(4):S97
Positive Serum Ethanol in Severe Traumatic Brain Injury is Associated with Better Long-Term Functional Outcomes
Thelin EP; Riddez L; Bellander B-M; Talving P; Mohseni S
Conference publication: JOURNAL OF NEUROTRAUMA. 2015;32(12):A30
NEURON-SPECIFIC ENOLASE IS SIGNIFICANTLY CORRELATED TO OUTCOME POST TRAUMATIC BRAIN INJURY, ALBEIT NOT IN PRESENCE OF SERUM S100B
Thelin E; Jeppsson E; Nelson D; Mondello S; Svensson M; Bellander B-M
Doctoral thesis: 2015
On biomarkers in traumatic brain injury
Thelin E
Conference publication: JOURNAL OF NEUROTRAUMA. 2014;31(5):A30
THE CLINICAL PITFALLS AND POSSIBILITIES USING S100B MONITORING IN NEURO INTENSIVE CARE IN PATIENTS SUFFERING FROM TRAUMATIC BRAIN INJURY
Thelin E; Bellander B-M
Conference publication: JOURNAL OF NEUROTRAUMA. 2013;30(15):A42
GLOBAL MICRODIALYSIS PREDICTS OUTCOME IN SEVERE TRAUMATIC BRAIN INJURY
Thelin EP; Bellander B-M
Conference publication: JOURNAL OF NEUROTRAUMA. 2011;28(6):A55
THE SENSITIVITY AND ROLE OF PROTEIN S100B IN DETECTING SECONDARY INJURIES AFTER TRAUMATIC BRAIN INJURY IN HUMANS
Thelin E; Johannesson L; Bellander B-M
Conference publication: JOURNAL OF NEUROTRAUMA. 2011;28(5):A20
THE TEMPORAL PROFILES IN SERUM CONCENTRATIONS OF THE BIOMARKER S100B IN THE FIRST 48HOURS AFTER TRAUMATIC BRAIN INJURY CORRESPOND TO OUTCOME
Thelin E; Johannesson L; Bellander B-M
Conference publication: JOURNAL OF NEUROTRAUMA. 2009;26(8):A44
THE TEMPORAL PROFILES IN SERUM CONCENTRATIONS OF S100B AFTER TRAUMATIC BRAIN INJURY CORRESPOND TO OUTCOME
Thelin E; Bellander B-M
Conference publication: JOURNAL OF NEUROTRAUMA. 2008;25(7):896
Secondary peaks in serum S100B in humans following traumatic brain injury is not related to monitored secondary insults
Thelin E; Bellander B-M
Conference publication: JOURNAL OF NEUROTRAUMA. 2006;23(5):749
Acute changes in COX-2 mRNA expression and compound EEG after penetrating TBI in the rat
Risling M; Davidsson J; Thelin E; Larsson IL; Angeria M; Skold M
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Grants

Dynamic Prediction Model of Outcome following Traumatic Brain Injury
Swedish Brain Foundation
31 July 2023 - 31 December 2024
Inflammation and neurodegeneration in chronic traumatic brain injury
The Swedish Society of Medicine
31 July 2023 - 27 June 2025
Neuroinflammation vid traumatisk hjärnskada: Fokus på blod-hjärnbarriären, förbättrad diagnostik och anti-inflammatorisk behandling
Region Stockholm ALF
1 January 2023 - 31 December 2024
Långtidsuppföljning vid traumatisk hjärnskada
KI Forskningsbidrag 2022-2023
7 November 2022 - 6 November 2023
Neuroinflammation vid traumatisk hjärnskada: Fokus på blod-hjärnbarriären, förbättrad diagnostik och anti-inflammatorisk behandling
The Strategic Research Area Neuroscience (StratNeuro)
1 January 2021 - 31 December 2022
Neuroinflammation vid traumatisk hjärnskada: Fokus på blod-hjärnbarriären, förbättrad diagnostik och anti-inflammatorisk behandling
Region Stockholm ALF
1 January 2021 - 31 December 2022
New diagnostic tools and treatments for Alzheimers Disease, Traumatic brain injury and small vascular disease
Erling-Perssons Stiftelse
1 January 2020 - 31 December 2022
Analysis of the cerebro-vascular auto-regulation in traumatic brain injury
Swedish Brain Foundation
4 November 2019 - 31 December 2020
Randomized Clinical Trial on Interleukin-1 receptor antagonist in traumatic brain injury
Swedish Society for Medical Research
1 May 2017 - 5 November 2018
Interleukine-1 receptor antagonist treatment in traumatic brain injury
The Swedish Brain Foundation
7 November 2016 - 5 November 2018
Randomized Clinical Trial on Interleukin-1 receptor antagonist in traumatic brain injury
The Swedish Society of Medicine
6 June 2016 - 5 June 2017

Employments

Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2027

Degrees and Education

Docent, Karolinska Institutet, 2022
Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2015
University Medical Degree, Karolinska Institutet, 2009

Articles

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Grants

Employments

Degrees and Education

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