Charlotte Hedin
Adjunct Lecturer
E-mail: charlotte.hedin@ki.se
Visiting address: Eugeniavägen 11 B4:09, 17164 Solna
Postal address: K2 Medicin, Solna, K2 Reuma Hedin C, 171 77 Stockholm
About me
- Dr Charlotte Hedin is a specialist in gastroenterology and internal medicine
at the Karolinska University Hospital in Stockholm. She completed her PhD
"Microbial, immunological, phenotypic and genetic markers of risk: aspects of
Crohn’s disease that are shared by unaffected siblings" at King’s College
London and Queen Mary University of London. In 2017 she was awarded a UEG
Rising Star award for her research in IBD and in 2018 she was awarded the
Karolina prize for “Exemplary patient flow and quality work” at the
Karolinska Hospital. She holds a clinical post-doctorate from the Karolinska
Hospital. She is a member of the Swedish Organisation for the study of IBD
(SOIBD)) and is committee member for the European Crohn’s and Colitis
Organisation (ECCO). Dr Hedin’s research focusses on: 1. Extraintestinal
inflammation in IBD inlcuding PSC, 2. Delineating pathogenic pathways in IBD
through studying at-risk individuals (families of IBD patients) and 3.
Defining the process of mucosal healing.
2018 Karolina prize for “Exemplary patient flow and quality work”
2017 UEG Rising Star Award
2016 Swedish Medical Society prize for best scientific application
2013 Prize for best inflammatory bowel disease oral presentation of an
abstract at the British Society of Gastroenterology Annual Meeting
2011 First prize in the oral presentation competition in the King’s College
London Postgraduate Research Symposium
2010 Runner-up in poster competition King’s College London Postgraduate
Research Symposium
2004 British Infection Society Spring Meeting presentation prize
Research
- Lynch KD, Chapman RW, Keshav S, Montano-Loza AJ, Mason AL, Kremer AE, Vetter
M, de Krijger M, Ponsioen CY, Trivedi P, Hirschfield G, Schramm C, Liu CH,
Bowlus CL, Estes DJ, Pratt D, Hedin C, Bergquist A, de Vries AC, van der
Woude CJ, Yu L, Assis DN, Boyer J, Ytting H, Hallibasic E, Trauner M,
Marschall HU, Daretti LM, Marzioni M, Yimam KK, Perin N, Floreani A,
Beretta-Piccoli BT, Rogers JK - International Primary Sclerosing Cholangitis
Study Group (IPSCSG), Levy C. Effects of Vedolizumab in Patients With Primary
Sclerosing Cholangitis and Inflammatory Bowel Diseases. Clin Gastroenterol
Hepatol. 2020 Jan - 18(1):179-187
Hedin CRH, Vavricka SR, Stagg AJ, Schoepfer A, Raine T, Puig L, Pleyer U,
Navarini A, van der Meulen-de Jong AE, Maul J, Katsanos K, Kagramanova A,
Greuter T, González-Lama Y, van Gaalen F, Ellul P, Burisch J, Bettenworth D,
Becker MD, Bamias G, Rieder F. The Pathogenesis of Extraintestinal
Manifestations: Implications for IBD Research, Diagnosis, and Therapy. J
Crohns Colitis. 2019 Apr 26 - 13(5):541-554.
Hedin C, van der Gast CJ, Rogers GB, Cuthbertson L, McCartney S, Stagg AJ,
Lindsay JO, Whelan K. Siblings of patients with Crohn's disease exhibit a
biologically relevant dysbiosis in mucosal microbial metacommunities. Gut.
2016 Jun - 65(6):944-53
Hedin CR, McCarthy NE, Louis P, Farquharson FM, McCartney S, Taylor K,
Prescott NJ, Murrells T, Stagg AJ, Whelan K, Lindsay JO. Altered intestinal
microbiota and blood T cell phenotype are shared by patients with Crohn's
disease and their unaffected siblings. Gut. 2014 Oct - 63(10):1578-86
Hedin CRH, Stagg AJ, Whelan K, Lindsay JO. Family studies in Crohn’s
disease: New horizons in understanding disease pathogenesis, risk and
prevention. Gut 2012 - 61: 311-318
Hedin CRH, Mullard M, Sharratt E, Jansen C, Sanderson JD, Shirlaw P, Howe LC,
Djemal S, Stagg AJ, Lindsay JO and Whelan K Probiotic and Prebiotic Use in
Patients with Inflammatory Bowel Disease: A Case-Control Study. Inflammatory
Bowel Diseases 2010 - 16(12): 2099-108
Hedin C, Whelan K, Lindsay JO Evidence for the use of probiotics and
prebiotics in inflammatory bowel disease: a review of clinical trials. Proc
Nutr Soc 2007 - 66 (3): 307-315
McCarthy NE, Hedin CR, Sanders TJ, Amon P, Hoti I, Ayada I, Baji V, Giles EM,
Wildemann M, Bashir Z, Whelan K, Sanderson I, Lindsay JO, Stagg AJ.
Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn's
disease. J Clin Invest. 2015 - 125(8):3215-25.
Benjamin JL, Hedin CRH, Koutsoumpas A, Ng SC, McCarthy NE, Prescott NJ,
Pessoa-Lopes P, Mathew CG, Sanderson JD, Hart AL, Kamm MA, Knight SC, Forbes
A, Stagg AJ, Lindsay JO, Whelan K. Smokers with active Crohn's disease have a
clinically relevant dysbiosis of the gastrointestinal microbiota Inflammatory
Bowel Diseases 2012 - 18(6): 1092–1100
Goodhand J, Hedin CR, Croft NM, Lindsay JO. Adolescents with IBD: The
importance of structured transition care. Journal of Crohn's and Colitis
2011 - 5(6): 509-519
Benjamin JL, Hedin CRH, Koutsoumpas A, Ng SC, McCarthy NE, Hart AL, Kamm MA,
Sanderson JD, Knight SC, Forbes A, Stagg AJ, Whelan K, and Lindsay JO A
randomised, double blind placebo controlled trial of fructo-oligosaccharides
in active Crohn’s disease. Gut 2011 - 60: 923-929
Hedin CRH. In: Smith P, Gill J, Nijjer S, and Levy J, eds. Secrets of
Success: Getting into academic training. 1 ed. Royal Society of Medicine
Press Ltd, 2010.
Articles
- Article: JOURNAL OF CROHN'S AND COLITIS. 2024;:jjae169
- Article: FAMILIAL CANCER. 2024;23(4):599-605
- Article: EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2024
- Article: JOURNAL OF CROHN'S AND COLITIS. 2024;18(10):1583-1595
- Article: GASTROENTEROLOGY. 2024;:S0016-5085(24)05539-2
- Article: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2024;60(6):765-777
- Article: NATURE COMMUNICATIONS. 2024;15(1):4567
- Article: JOURNAL OF CROHN'S AND COLITIS. 2023;17(12):1962-1967
- Article: GASTROENTEROLOGY. 2023;165(6):1443-1457
- Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2023;58(10):1131-1138
- Article: CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY. 2023;14(8):e00605
- Article: IMMUNITY. 2023;56(6):1285-1302.e7
- Article: GASTROENTEROLOGY. 2023;164(4):619-629
- Article: COLORECTAL DISEASE. 2023;25(4):695-706
- Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2023;21(3):771-788.e10
- Article: NATURE BIOTECHNOLOGY. 2023;41(2):222-231
- Article: JOURNAL OF CROHN'S AND COLITIS. 2023;17(1):1-27
- Article: GASTROENTEROLOGY. 2022;163(5):1364-1376.e10
- Article: GASTROENTEROLOGY. 2022;163(3):685-698
- Article: UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2022;10(7):631-639
- Article: SCIENCE IMMUNOLOGY. 2022;7(70):eabj8301
- Article: COLORECTAL DISEASE. 2022;24(4):470-483
- Article: JOURNAL OF CROHN'S AND COLITIS. 2022;16(2):179-189
- Article: JOURNAL OF CROHN'S AND COLITIS. 2022;16(1):2-17
- Article: CLINICAL AND EXPERIMENTAL GASTROENTEROLOGY. 2022;15:129-144
- Article: JOURNAL OF CROHN'S AND COLITIS. 2021;15(9):1443-1454
- Article: CELL RESEARCH. 2021;31(5):554-568
- Article: GASTROENTEROLOGY. 2020;159(6):2092-2100.e5
- Article: BMC MEDICAL GENETICS. 2020;21(1):204
- Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2020;55(10):1185-1192
- Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2020;18(10):2295-2304.e2
- Article: EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2020;32(8):1062-1066
- Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2020;18(1):179-187.e6
- Article: BEST PRACTICE AND RESEARCH: CLINICAL GASTROENTEROLOGY. 2018;32-33:27-34
- Article: GUT MICROBES. 2017;8(4):359-365
- Article: GUT. 2016;65(6):944-953
- Article: JOURNAL OF CROHN'S AND COLITIS. 2015;9(11):1024-1031
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2015;125(8):3215-3225
- Article: GUT. 2014;63(10):1578-1586
- Article: JOURNAL OF IMMUNOLOGY. 2013;191(5):2752-2763
- Article: INFLAMMATORY BOWEL DISEASES. 2012;18(6):1092-1100
- Article: GUT. 2012;61(2):311-318
- Article: INFLAMMATORY BOWEL DISEASES. 2011;17(10):2027-2037
- Article: GUT. 2011;60(7):923-929
- Article: INFLAMMATORY BOWEL DISEASES. 2010;16(12):2099-2108
- Article: NEUROSCIENCE. 1998;84(2):325-330
- Article: JOURNAL OF NEUROCHEMISTRY. 1997;69(6):2378-2386
- Show more
All other publications
- Editorial comment: THE LANCET GASTROENTEROLOGY AND HEPATOLOGY. 2024;9(6):489-491
- Review: JOURNAL OF INTERNAL MEDICINE. 2023;294(6):708-720
- Review: JOURNAL OF CROHN'S AND COLITIS. 2023;17(2):153-169
- Review: NATURE REVIEWS GASTROENTEROLOGY AND HEPATOLOGY. 2022;19(8):493-507
- Review: JOURNAL OF CROHN'S AND COLITIS. 2021;15(11):1959-1973
- Review: JOURNAL OF CROHN'S AND COLITIS. 2021;15(10):1605-1620
- Review: JOURNAL OF INTERNAL MEDICINE. 2021;290(2):257-278
- Published conference paper: JOURNAL OF CROHN'S AND COLITIS. 2019;13(5):541-554
- Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2019;89(3):e12745
- Review: JOURNAL OF CROHN'S AND COLITIS. 2011;5(6):509-519
- Meeting abstract: GUT. 2010;59:A1-A2
- Meeting abstract: GUT. 2010;59:A5
- Published conference paper: PROCEEDINGS OF THE NUTRITION SOCIETY. 2007;66(3):307-315
- Letter: CLINICAL INFECTIOUS DISEASES. 2005;41(6):916-917
- Editorial comment: CLINICAL INFECTIOUS DISEASES. 2005;40(9):1368-1371