Charlotte Gran

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About me

MD specialist in clinical chemistry. Postdoc in Jovan Antovic group at MMK
with a research focus on the development of extracellular vesicles assays.
After receiving her medical degree from the Karolinska Institutet, Stockholm
in 2007, Charlotte did her internship at St:Görans Hospital, Stockholm,
followed by residency in clinical chemistry at Karolinska University
Hospital. She is a MD specialist in clinical chemistry since 2019 and
responsible for routine hematology assays, platelet dysfunction assays and
fetomaternal transfusion assays at Karolinska University Laboratory. She
teaches on hematology assays and anemia assessment for medical student at
Karolinska Instituet
She defended her thesis, “Strategies to assess and improve prognostication
of plasma cell disorder”, in March 2021 at Center for Hematology and
Regenerative Medicine, department of Medicine Huddinge, Karolinska
Institutet. In summer 2021 she joined Jovan Antovic group as a postdoc. Her
research focus is the development of extracellular vesicles assays to utilize
as prognostics markers primarily in cancer associated thromboembolism.

Articles

Article: PLOS ONE. 2024;19(8):e0309112
The role of complement and extracellular vesicles in the development of pulmonary embolism in severe COVID-19 cases
Dumitrescu G; Antovic J; Soutari N; Gran C; Antovic A; Al-Abani K; Grip J; Rooyackers O; Taxiarchis A
Article: BLOOD ADVANCES. 2022;6(17):5009-5023
Linked-read whole-genome sequencing resolves common and private structural variants in multiple myeloma
Pena-Perez L; Frengen N; Hauenstein J; Gran C; Gustafsson C; Eisfeldt J; Kierczak M; Taborsak-Lines F; Olsen R-A; Wallblom A; Krstic A; Ewels P; Lindstrand A; Mansson R
Article: CELL REPORTS MEDICINE. 2022;3(2):100508
Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma
Nahi H; Chrobok M; Meinke S; Gran C; Marquardt N; Afram G; Sutlu T; Gilljam M; Stellan B; Wagner AK; Blomberg P; Holmqvist P-H; Walther-Jallow L; Mellstrom K; Liwing J; Gustafsson C; Mansson R; Klimkowska M; Gahrton G; Lund J; Ljungman P; Ljunggren H-G; Alici E
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(8):925-933
Low dose venetoclax as a single agent treatment of plasma cell malignancies harboring t(11;14)
Nahi H; Kashif M; Klimkowska M; Karvouni M; Wallblom A; Gran C; Hauenstein J; Frengen N; Gustafsson C; Afram G; Uttervall K; Lund J; Mansson R; Wagner AK; Alici E
Article: LEUKEMIA AND LYMPHOMA. 2021;62(9):2227-2234
Involved free light chain: an early independent predictor of response and progression in multiple myeloma
Gran C; Afram G; Liwing J; Verhoek A; Nahi H
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(1):23-30
Comparative evaluation of involved free light chain and monoclonal spike as markers for progression from monoclonal gammopathy of undetermined significance to multiple myeloma
Gran C; Liwing J; Wagner AK; Verhoek A; Gezin A; Alici E; Nahi H
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2020;105(6):751-754
Outcome of COVID-19 in multiple myeloma patients in relation to treatment
Susek KH; Gran C; Ljunggren H-G; Alici E; Nahi H
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2020;105(2):196-202
Impact of performance status on overall survival in patients with relapsed and/or refractory multiple myeloma: Real-life outcomes of daratumumab treatment
Afram G; Gran C; Borg Bruchfeld J; Wagner AK; Hussain A; Alici E; Nahi H
Article: ACTA HAEMATOLOGICA. 2020;143(5):500-503
Rapid Complete Response to Single-Agent Bcl-2 Inhibitor Venetoclax in a Heart-Transplanted Patient with Triple Refractory Immunoglobulin Light-Chain Amyloidosis
Gran C; Bruchfeld JB; Ellin F; Nahi H
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2019;103(6):588-596
Translocation (11;14) in newly diagnosed multiple myeloma, time to reclassify this standard risk chromosomal aberration?
Gran C; Uttervall K; Bruchfeld JB; Wallblom A; Alici E; Gahrton G; Nahi H
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2019;103(3):247-254
Upfront bortezomib, lenalidomide, and dexamethasone compared to bortezomib, cyclophosphamide, and dexamethasone in multiple myeloma
Uttervall K; Bruchfeld JB; Gran C; Walinder G; Mansson R; Lund J; Gahrton G; Alici E; Nahi H
Article: PLOS ONE. 2019;14(2):e0211927
Infectious complications and NK cell depletion following daratumumab treatment of Multiple Myeloma
Nahi H; Chrobok M; Gran C; Lund J; Gruber A; Gahrton G; Ljungman P; Wagner AK; Alici E
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2018;100(4):386-388
Case Report: Treatment of light-chain amyloidosis with daratumumab monotherapy in two patients
Gran C; Gahrton G; Alici E; Nahi H
Article: SCANDINAVIAN JOURNAL OF CLINICAL AND LABORATORY INVESTIGATION. 2015;75(8):652-658
Validation of a competitive ELISA assay for the quantification of human serum hepcidin
Dahlfors G; Stal P; Hansson EC; Barany P; Sisowath C; Onelov L; Nelson D; Eggertsen G; Marmur J; Beshara S

All other publications

Meeting abstract: BLOOD. 2022;140:2823-2824
Tissue Factor Positive Extracellular Vesicles and Risk of Thromboembolism in Diffuse Large B-Cell Lymphoma: A Prospective Exploratory Study
Otasevic V; Gran C; Milic N; Vukovic V; Mihaljevic B; Fareed J; Soutari NMH; Antovic J; Antic D
Letter: BLOOD. 2021;137(9):1260-1263
Absence of a common founder mutation in patients with cooccurring myelodysplastic syndrome and plasma cell disorder
Klimkowska M; Nannya Y; Gran C; Mansson R; Douagi I; Ogawa S; Nahi H; Tobiasson M
Thesis / dissertation: 2021
Strategies to assess and improve prognostication of plasma cell disorders
Gran, Charlotte
Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(3):E63-E65
Dynamic follow-up of smoldering multiple myeloma identifies a subset of patients at high risk of progression
Gran C; Luong V; Bruchfeld JB; Liwing J; Afram G; Lund J; Usmani S; Alici E; Nahi H
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2020;189(5):e213-e217
Treosulfan conditioning for allogeneic transplantation in multiple myeloma - improved overall survival in first line haematopoietic stem cell transplantation - a large retrospective study by the Chronic Malignancies Working Party of the EBMT
Gran C; Wang J; Nahi H; Koster L; Gahrton G; Einsele H; Niittyvoupio R; Edinger M; Beelen D; Ciceri F; Bornhaeuser M; Finke J; de Wreede LC; Ljungman P; Mielke S; Tischer J; Garderet L; Schoenland S; Yakoub-Agha I; Kroeger N
Meeting abstract: CLINICAL LYMPHOMA, MYELOMA AND LEUKEMIA. 2019;19(10):E206
Treosulfan Conditioning for Allogeneic Transplantation in Multiple Myeloma - Improved Overall Survival in first line Hematopoietic Stem Cell Transplantation
Gran C; Wang J; Nahi H; Koster L; Gahrton G; Wolschke C; Einsele H; Niittyvoupio R; Blaise D; Niederwieser D; Meier E; Petersen E; de Wreede LC; Ljungman P; Bourhis JH; Veelken H; Beelen D; Stelljes M; Gerbitz A; Vincent L; Finke J; Passweg J; Milpied N; Stoelzel F; Yakoub-Agha I; Schoenland S; Garderet L; Kroger N
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2016;75:281
DRVVT AND APTT RATIOS FOR LABORATORY DETECTION OF LUPUS ANTICOAGULANT - TO NORMALIZE OR NOT TO NORMALIZE THAT IS THE QUESTION
Hannson EC; Norberg E-M; Berndtsson M; Antovic JP

Employments

Postdoctoral Studies, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2023-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medicine, Huddinge, Karolinska Institutet, 2021
University Medical Degree, Karolinska Institutet, 2007

Supervisor

Sanna Norén, Hemostasis in liver cirrhosis and hepatocellular cancer (HELICS), 2022

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