Bruna Gigante

About me
Publications
Grants
CV
Public outreach and news

About me

*Current position*
Senior lecturer in epidemiology with focus on cardiovascular medicine at
Karolinska Institutet since 2015. This position combines 50% clinical work as
senior consultant in cardiology at the Department of Cardiology, Danderyds
Hospital and 50% research at the Department of Medicine Solna, Karolinska
Institutet.
*Education*
*1994*. Medical Doctor (MD). Federico II University, Naples, Italy.
*1995*. Legitimation Federico II University, Naples, Italy. (Legitimerade
läkare)
*1998*. Specialist competence in Cardiology. Federico II University Naples,
Italy.
*2006*. PhD in Experimental and Clinical Medicine. Federico II University,
Naples, Italy.

Research

Overarching aim of my line of research is to define clinical and molecular
profiles associated with the risk of cardiovascular diseases, in particular
myocardial infarction and stroke.
You can read more about my research profile
at https://ki.se/en/meds/team-bruna-gigante [1].
[1] https://ki.se/en/meds/team-bruna-gigante

Articles

Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2025;419:132698
Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis.
Gigante B; Chen Q; Björkbacka H; Björnson E; Brinck J; Chorell E; Djekic D; Edsfeldt A; Engström G; Eriksson JW; Gottsäter A; Gummesson A; Hagström E; Hedin U; Jernberg T; Johnston N; Nilsson L; Nyström F; Otten J; Rosengren A; Söderberg S; Haglöw JT; Östgren CJ
Article: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2024;59(9):1111-1121
Prevalence and risk factors of metabolic dysfunction-associated steatotic liver disease in south Central Uganda: A cross-sectional survey
Enriquez R; Homsi M; Ssekubugu R; Nabukalu D; Zeebari Z; Marrone G; Gigante B; Chang LW; Reynolds SJ; Nalugoda F; Ekstroem AM; Hagstroem H; Nordenstedt H
Article: JOURNAL OF STROKE AND CEREBROVASCULAR DISEASES. 2024;33(4):107629
Brain MRI microbleeds and risk of intracranial hemorrhage in atrial fibrillation patients: A Swedish case-control study
Aspberg S; Cheng D; von Heijne A; Gigante B; Singer DE
Article: BIOMEDICINES. 2024;12(4):737
Determinants of Carotid Wall Echolucency in a Cohort of European High Cardiovascular Risk Subjects: A Cross-Sectional Analysis of IMPROVE Baseline Data
Frigerio B; Coggi D; Bonomi A; Amato M; Capra N; Colombo GI; Sansaro D; Ravani A; Savonen K; Giral P; Gallo A; Pirro M; Gigante B; Eriksson P; Strawbridge RJ; Mulder DJ; Tremoli E; Veglia F; Baldassarre D
Article: THROMBOSIS JOURNAL. 2024;22(1):16
Causes of death after first time venous thromboembolism
Lonnberg F; Roos A; Farm M; Heurlin A; Okas M; Gigante B; Siddiqui AJ
Article: CIRCULATION. 2024;149(4):305-316
Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease: Pooled De Novo Results From 15 Observational Studies
Laguzzi F; Akesson A; Marklund M; Qian F; Gigante B; Bartz TM; Bassett JK; Birukov A; Campos H; Hirakawa Y; Imamura F; Jaeger S; Lankinen M; Murphy RA; Senn M; Tanaka T; Tintle N; Virtanen JK; Yamagishi K; Allison M; Brouwer IA; De Faire U; Eiriksdottir G; Ferrucci L; Forouhi NG; Geleijnse JM; Hodge AM; Kimura H; Laakso M; Riserus U; van Westing AC; Bandinelli S; Baylin A; Giles GG; Gudnason V; Iso H; Lemaitre RN; Ninomiya T; Post WS; Psaty BM; Salonen JT; Schulze MB; Tsai MY; Uusitupa M; Wareham NJ; Oh S-W; Wood AC; Harris WS; Siscovick D; Mozaffarian D; Leander K
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2024;39(1):35-49
Pulmonary function and atherosclerosis in the general population: causal associations and clinical implications
Engstroem G; Lampa E; Dekkers K; Lin Y-T; Ahlm K; Ahlstroem H; Alfredsson J; Bergstroem G; Blomberg A; Brandberg J; Caidahl K; Cederlund K; Duvernoy O; Engvall JE; Eriksson MJ; Fall T; Gigante B; Gummesson A; Hagstroem E; Hamrefors V; Hedner J; Janzon M; Jernberg T; Johnson L; Lind L; Lindberg E; Mannila M; Nilsson U; Persson A; Persson HL; Persson M; Ramnemark A; Rosengren A; Schmidt C; Skoglund Larsson L; Skoeld CM; Swahn E; Soederberg S; Toren K; Waldenstroem A; Wollmer P; Zaigham S; Oestgren CJ; Sundstroem J
Article: CARDIOVASCULAR RESEARCH (CVR). 2023;119(16):2594-2606
A machine learning based approach to identify carotid subclinical atherosclerosis endotypes
Chen QS; Bergman O; Ziegler L; Baldassarre D; Veglia F; Tremoli E; Strawbridge RJ; Gallo A; Pirro M; Smit AJ; Kurl S; Savonen K; Lind L; Eriksson P; Gigante B
Article: EUROPEAN HEART JOURNAL. 2023;44(32):3040-3058
Management of patients on antithrombotic therapy with severe infections: a joint clinical consensus statement of the ESC Working Group on Thrombosis, the ESC Working Group on Atherosclerosis and Vascular Biology, and the International Society on Thrombosis and Haemostasis
Gigante B; Levy JH; van Gorp E; Bartoloni A; Bochaton-Piallat M-L; Back M; ten Cate H; Christersson C; Ferreiro JL; Geisler T; Lutgens E; Schulman S; Storey RF; Thachil J; Vilahur G; Liaw PC; Rocca B
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2023;82(4):336-349
Omega-3 Fatty Acid Biomarkers and Incident Atrial Fibrillation
Qian F; Tintle N; Jensen PN; Lemaitre RN; Imamura F; Feldreich TR; Nomura SO; Guan W; Laguzzi F; Kim E; Virtanen JK; Steur M; Bork CS; Hirakawa Y; O'Donoghue ML; Sala-Vila A; Korat AVA; Sun Q; Rimm EB; Psaty BM; Heckbert SR; Forouhi NG; Wareham NJ; Marklund M; Riserus U; Lind L; Arnlov J; Garg P; Tsai MY; Pankow J; Misialek JR; Gigante B; Leander K; Pester JA; Albert CM; Kavousi M; Ikram A; Voortman T; Schmidt EB; Ninomiya T; Morrow DA; Bayes-Genis A; O'Keefe JH; Ong KL; Wu JHY; Mozaffarian D; Harris WS; Siscovick DS
Article: HEMASPHERE. 2023;7(6):e900
Antithrombotic Treatment in Patients With Hemophilia: an EHA-ISTH-EAHAD-ESO Clinical Practice Guidance
Schutgens REG; Jimenez-Yuste V; Escobar M; Falanga A; Gigante B; Klamroth R; Lassila R; Leebeek FWG; Makris M; Owaidah T; Sholzberg M; Tiede A; Werring DJ; van der Worp HB; Windyga J; Castaman G
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY: HEART & VASCULATURE. 2023;46:101215
The association between circulating lipoprotein subfractions and lipid content in coronary atheromatous plaques assessed by near-infrared spectroscopy
Saether JC; Vesterbekkmo EK; Gigante B; Giskeodegard GF; Bathen TF; Follestad T; Wiseth R; Madssen E; Bye A
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2023;16(3):236-247
Cross-Sectional Gene-Smoking Interaction Analysis in Relation to Subclinical Atherosclerosis-Results From the IMPROVE Study
Maitusong B; Laguzzi FJ; Strawbridge R; Baldassarre D; Veglia FE; Humphries S; Savonen K; Kurl S; Pirro MJ; Smit A; Giral P; Silveira A; Tremoli E; Hamsten A; de Faire U; Gigante B; Leander K
Journal article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2023;30(Supplement_1)
The association between circulating lipoprotein subfractions and lipid content in coronary atheromatous plaques assessed by near-infrared spectroscopy
Saether J; Vesterbekkmo EK; Gigante B; Giskeodegard GF; Bathen TF; Follestad T; Wiseth R; Madssen E; Bye A
Article: SCIENTIFIC REPORTS. 2023;13(1):7580
Associations between circulating microRNAs and lipid-rich coronary plaques measured with near-infrared spectroscopy
Saether JC; Vesterbekkmo EK; Taraldsen MD; Gigante B; Follestad T; Rosjo HR; Omland T; Wiseth R; Madssen E; Bye A
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2023;12(3):e027089
Elevated Uric Acid Is Associated With New-Onset Atrial Fibrillation: Results From the Swedish AMORIS Cohort
Ding M; Viet NN; Gigante B; Lind V; Hammar N; Modig K
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2023;110(2):284-299
Loci for insulin processing and secretion provide insight into type 2 diabetes risk
Broadaway KA; Yin X; Williamson A; Parsons VA; Wilson EP; Moxley AH; Vadlamudi S; Varshney A; Jackson AU; Ahuja V; Bornstein SR; Corbin LJ; Delgado GE; Dwivedi OP; Silva LF; Frayling TM; Grallert H; Gustafsson S; Hakaste L; Hammar U; Herder C; Herrmann S; Hojlund K; Hughes DA; Kleber ME; Lindgren CM; Liu C-T; Luan J; Malmberg A; Moissl AP; Morris AP; Perakakis N; Peters A; Petrie JR; Roden M; Schwarz PEH; Sharma S; Silveira A; Strawbridge RJ; Tuomi T; Wood AR; Wu P; Zethelius B; Baldassarre D; Eriksson JG; Fall T; Florez JC; Fritsche A; Gigante B; Hamsten A; Kajantie E; Laakso M; Lahti J; Lawlor DA; Lind L; Maerz W; Meigs JB; Sundstrom J; Timpson NJ; Wagner R; Walker M; Wareham NJ; Watkins H; Barroso I; O'Rahilly S; Grarup N; Parker SCJ; Boehnke M; Langenberg C; Wheeler E; Mohlke KL
Article: PHYSIOLOGICAL GENOMICS. 2023;55(1):16-26
Small LDL subfractions are associated with coronary atherosclerosis despite no differences in conventional lipids
Saether JC; Klevjer M; Giskeodegard GF; Bathen TF; Gigante B; Gjaere S; Myhra M; Vesterbekkmo EK; Wiseth R; Madssen E; Bye A
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(1):103374
Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis
Velasquez IM; Malarstig A; Baldassarre D; Borne Y; de Faire U; Engstrom G; Eriksson P; Giral P; Humphries SE; Kurl S; Leander K; Lind L; Linden A; Orsini N; Pirro M; Silveira A; Smit AJ; Tremoli E; Veglia F; Strawbridge RJ; Gigante B
Article: CYTOKINE. 2022;159:156020
IL-6 signalling biomarkers in hospitalised patients with moderate to severe SARS-CoV-2 infection in a single centre study in Sweden
Ziegler L; Lundstrom A; Havervall S; Thalin C; Gigante B
Article: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. 2022;6(7):e12823
Antithrombotic treatment switching in elderly patients with atrial fibrillation and the risk of thromboembolism, bleeding, and cardiac death
Ehrlinder H; Orsini N; Modig K; Wallen H; Gigante B
Article: OPEN HEART. 2022;9(2):e002080
Is the association of QTc with atrial fibrillation and stroke in cohort studies a matter of time?
Radnahad N; Ehrlinder H; Leander K; Engdahl J; Wallen H; Gigante B
Article: PLOS MEDICINE. 2022;19(8):e1004044
Lipid levels in midlife and risk of atrial fibrillation over 3 decades-Experience from the Swedish AMORIS cohort: A cohort study
Ding M; Wennberg A; Gigante B; Walldius G; Hammar N; Modig K
Journal article: ATHEROSCLEROSIS. 2022;355:76
Small LDL subfractions are associated with coronary atherosclerosis
Sæther JC; Bye A; Klevjer M; Bathen TF; Giskeødegård G; Madssen E; Vesterbekkmo E; Wiseth R; Gjære S; Myhra M; Gigante B
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2022;29(7):1114-1123
The DASH diet is associated with a lower risk of heart failure: a cohort study
Ibsen DB; Levitan EB; Akesson A; Gigante B; Wolk A
Article: JOURNAL OF THE INTERNATIONAL AIDS SOCIETY. 2022;25(4):e25901
Prevalence of cardiovascular risk factors by HIV status in a population-based cohort in South Central Uganda: a cross-sectional survey
Enriquez R; Ssekubugu R; Ndyanabo A; Marrone G; Gigante B; Chang LW; Reynolds SJ; Nalugoda F; Ekstrom AM; Sewankambo NK; Serwadda DM; Nordenstedt H
Article: BIOFACTORS. 2022;48(1):100-110
Neutrophil to lymphocyte ratio is not related to carotid atherosclerosis progression and cardiovascular events in the primary prevention of cardiovascular disease: Results from the IMPROVE study
Mannarino MR; Bianconi V; Gigante B; Strawbridge RJ; Savonen K; Kurl S; Giral P; Smit A; Eriksson P; Tremoli E; Veglia F; Baldassarre D; Pirro M
Article: FRONTIERS IN PHYSIOLOGY. 2022;13:909870
Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis
Schillemans T; Tragante V; Maitusong B; Gigante B; Cresci S; Laguzzi F; Vikstrom M; Richards M; Pilbrow A; Cameron V; Foco L; Doughty RN; Kuukasjarvi P; Allayee H; Hartiala JA; Tang WHW; Lyytikainen L-P; Nikus K; Laurikka JO; Srinivasan S; Mordi IR; Trompet S; Kraaijeveld A; van Setten J; Gijsberts CM; Maitland-van der Zee AH; Saely CH; Gong Y; Johnson JA; Cooper-DeHoff RM; Pepine CJ; Casu G; Leiherer A; Drexel H; Horne BD; van der Laan SW; Marziliano N; Hazen SL; Sinisalo J; Kahonen M; Lehtimaki T; Lang CC; Burkhardt R; Scholz M; Jukema JW; Eriksson N; Akerblom A; James S; Held C; Hagstrom E; Spertus JA; Algra A; de Faire U; Akesson A; Asselbergs FW; Patel RS; Leander K
Article: SCIENTIFIC REPORTS. 2021;11(1):24440
The association of apolipoproteins with later-life all-cause and cardiovascular mortality: a population-based study stratified by age
Ding M; Wennberg A; Ek S; Santoni G; Gigante B; Walldius G; Hammar N; Modig K
Article: GLOBAL HEART. 2021;16(1):83-13
ECG Abnormalities and Arterial Stiffness by HIV Status among High-Risk Populations in Rakai, Uganda: A Pilot Study
Enriquez R; Ssekubugu R; Kigozi G; Nabukalu D; Marrone G; Rautiainen S; Gigante B; Reynolds SJ; Nalugoda F; Chang LW; Ekstrom AM; Sewankambo NK; Serwadda D; Nordenstedt H
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2021;28(12):1376-1385
Physical activity attenuates cardiovascular risk and mortality in men and women with and without the metabolic syndrome - a 20-year follow-up of a population-based cohort of 60-year-olds
Ekblom-Bak E; Halldin M; Vikstrom M; Stenling A; Gigante B; de Faire U; Leander K; Hellenius M-L
Journal article: EUROPEAN HEART JOURNAL. 2021;42(Supplement_1):ehab724.2510
IL6 trans-signalling is associated with a higher risk of cardiovascular events in individuals with diabetes
Ziegler L; Gigante B
Article: OPEN HEART. 2021;8(2):e001694
Interleukin 6 trans-signalling and the risk of future cardiovascular events in men and women
Miri Y; Leander K; Eriksson P; Gigante B; Ziegler L
Article: BMC NEUROLOGY. 2021;21(1):306
IL6 trans-signaling associates with ischemic stroke but not with atrial fibrillation
Ziegler L; Wallen H; Aspberg S; de Faire U; Gigante B
Article: BIOMEDICINES. 2021;9(7):841
Relationship between Circulating PCSK9 and Markers of Subclinical Atherosclerosis-The IMPROVE Study
Coggi D; Frigerio B; Bonomi A; Ruscica M; Ferri N; Sansaro D; Ravani A; Ferrante P; Damigella M; Veglia F; Capra N; Lupo MG; Macchi C; Savonen K; Silveira A; Kurl S; Giral P; Pirro M; Strawbridge RJ; Gigante B; Smit AJ; Tremoli E; Amato M; Baldassarre D
Article: NATURE GENETICS. 2021;53(6):840-860
The trans-ancestral genomic architecture of glycemic traits
Chen J; Spracklen CN; Marenne G; Varshney A; Corbin LJ; Luan J; Willems SM; Wu Y; Zhang X; Horikoshi M; Boutin TS; Magi R; Waage J; Li-Gao R; Chan KHK; Yao J; Anasanti MD; Chu AY; Claringbould A; Heikkinen J; Hong J; Hottenga J-J; Huo S; Kaakinen MA; Louie T; Maerz W; Moreno-Macias H; Ndungu A; Nelson SC; Nolte IM; North KE; Raulerson CK; Ray D; Rohde R; Rybin D; Schurmann C; Sim X; Southam L; Stewart ID; Wang CA; Wang Y; Wu P; Zhang W; Ahluwalia TS; Appel EVR; Bielak LF; Brody JA; Burtt NP; Cabrera CP; Cade BE; Chai JF; Chai X; Chang L-C; Chen C-H; Chen BH; Chitrala KN; Chiu Y-F; de Haan HG; Delgado GE; Demirkan A; Duan Q; Engmann J; Fatumo SA; Gayan J; Giulianini F; Gong JH; Gustafsson S; Hai Y; Hartwig FP; He J; Heianza Y; Huang T; Huerta-Chagoya A; Hwang MY; Jensen RA; Kawaguchi T; Kentistou KA; Kim YJ; Kleber ME; Kooner IK; Lai S; Lange LA; Langefeld CD; Lauzon M; Li M; Ligthart S; Liu J; Loh M; Long J; Lyssenko V; Mangino M; Marzi C; Montasser ME; Nag A; Nakatochi M; Noce D; Noordam R; Pistis G; Preuss M; Raffield L; Rasmussen-Torvik LJ; Rich SS; Robertson NR; Rueedi R; Ryan K; Sanna S; Saxena R; Schraut KE; Sennblad B; Setoh K; Smith AV; Sparso T; Strawbridge RJ; Takeuchi F; Tan J; Trompet S; van den Akker E; van der Most PJ; Verweij N; Vogel M; Wang H; Wang C; Wang N; Warren HR; Wen W; Wilsgaard T; Wong A; Wood AR; Xie T; Zafarmand MH; Zhao J-H; Zhao W; Amin N; Arzumanyan Z; Astrup A; Bakker SJL; Baldassarre D; Beekman M; Bergman RN; Bertoni A; Blueher M; Bonnycastle LL; Bornstein SR; Bowden DW; Cai Q; Campbell A; Campbell H; Chang YC; de Geus EJC; Dehghan A; Du S; Eiriksdottir G; Farmaki AE; Franberg M; Fuchsberger C; Gao Y; Gjesing AP; Goel A; Han S; Hartman CA; Herder C; Hicks AA; Hsieh C-H; Hsueh WA; Ichihara S; Igase M; Ikram MA; Johnson WC; Jorgensen ME; Joshi PK; Kalyani RR; Kandeel FR; Katsuya T; Khor CC; Kiess W; Kolcic I; Kuulasmaa T; Kuusisto J; Lall K; Lam K; Lawlor DA; Lee NR; Lemaitre RN; Li H; Lin S-Y; Lindstrom J; Linneberg A; Liu J; Lorenzo C; Matsubara T; Matsuda F; Mingrone G; Mooijaart S; Moon S; Nabika T; Nadkarni GN; Nadler JL; Nelis M; Neville MJ; Norris JM; Ohyagi Y; Peters A; Peyser PA; Polasek O; Qi Q; Raven D; Reilly DF; Reiner A; Rivideneira F; Roll K; Rudan I; Sabanayagam C; Sandow K; Sattar N; Schuermann A; Shi J; Stringham HM; Taylor KD; Teslovich TM; Thuesen B; Timmers PRHJ; Tremoli E; Tsai MY; Uitterlinden A; van Dam RM; van Heemst D; van Hylckama Vlieg A; van Vliet-Ostaptchouk JV; Vangipurapu J; Vestergaard H; Wang T; Willems van Dijk K; Zemunik T; Abecasis GR; Adair LS; Aguilar-Salinas CA; Alarcon-Riquelme ME; An P; Aviles-Santa L; Becker DM; Beilin LJ; Bergmann S; Bisgaard H; Black C; Boehnke M; Boerwinkle E; Boehm BO; Bonnelykke K; Boomsma DI; Bottinger EP; Buchanan TA; Canouil M; Caulfield MJ; Chambers JC; Chasman DI; Chen Y-DI; Cheng C-Y; Collins FS; Correa A; Cucca F; de Silva HJ; Dedoussis G; Elmstahl S; Evans MK; Ferrannini E; Ferrucci L; Florez JC; Franks PW; Frayling TM; Froguel P; Gigante B; Goodarzi MO; Gordon-Larsen P; Grallert H; Grarup N; Grimsgaard S; Groop L; Gudnason V; Guo X; Hamsten A; Hansen T; Hayward C; Heckbert SR; Horta BL; Huang W; Ingelsson E; James PS; Jarvelin M-R; Jonas JB; Jukema JW; Kaleebu P; Kaplan R; Kardia SLR; Kato N; Keinanen-Kiukaanniemi SM; Kim B-J; Kivimaki M; Koistinen HA; Kooner JS; Koerner A; Kovacs P; Kuh D; Kumari M; Kutalik Z; Laakso M; Lakka TA; Launer LJ; Leander K; Li H; Lin X; Lind L; Lindgren C; Liu S; Loos RJF; Magnusson PKE; Mahajan A; Metspalu A; Mook-Kanamori DO; Mori TA; Munroe PB; Njolstad I; O'Connell JR; Oldehinkel AJ; Ong KK; Padmanabhan S; Palmer CNA; Palmer ND; Pedersen O; Pennell CE; Porteous DJ; Pramstaller PP; Province MA; Psaty BM; Qi L; Raffel LJ; Rauramaa R; Redline S; Ridker PM; Rosendaal FR; Saaristo TE; Sandhu M; Saramies J; Schneiderman N; Schwarz P; Scott LJ; Selvin E; Sever P; Shu X-O; Slagboom PE; Small KS; Smith BH; Snieder H; Sofer T; Sorensen TIA; Spector TD; Stanton A; Steves CJ; Stumvoll M; Sun L; Tabara Y; Tai ES; Timpson NJ; Tonjes A; Tuomilehto J; Tusie T; Uusitupa M; van der Harst P; van Duijn C; Vitart V; Vollenweider P; Vrijkotte TGM; Wagenknecht LE; Walker M; Wang YX; Wareham NJ; Watanabe RM; Watkins H; Wei WB; Wickremasinghe AR; Willemsen G; Wilson JF; Wong T-Y; Wu J-Y; Xiang AH; Yanek LR; Yengo L; Yokota M; Zeggini E; Zheng W; Zonderman AB; Rotter JI; Gloyn AL; McCarthy MI; Dupuis J; Meigs JB; Scott RA; Prokopenko I; Leong A; Liu C-T; Parker SCJ; Mohlke KL; Langenberg C; Wheeler E; Morris AP; Barroso I
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2021;10(11):e020419
Association Between Uric Acid, Carotid Intima-Media Thickness, and Cardiovascular Events: Prospective Results From the IMPROVE Study
Mannarino MR; Pirro M; Gigante B; Savonen K; Kurl S; Giral P; Smit A; Veglia F; Tremoli E; Baldassarre D
Article: MOLECULAR PSYCHIATRY. 2021;26(6):2111-2125
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
de las Fuentes L; Sung YJ; Noordam R; Winkler T; Feitosa MF; Schwander K; Bentley AR; Brown MR; Guo X; Manning A; Chasman DI; Aschard H; Bartz TM; Bielak LF; Campbell A; Cheng C-Y; Dorajoo R; Hartwig FP; Horimoto ARVR; Li C; Li-Gao R; Liu Y; Marten J; Musani SK; Ntalla I; Rankinen T; Richard M; Sim X; Smith AV; Tajuddin SM; Tayo BO; Vojinovic D; Warren HR; Xuan D; Alver M; Boissel M; Chai J-F; Chen X; Christensen K; Divers J; Evangelou E; Gao C; Girotto G; Harris SE; He M; Hsu F-C; Kuehnel B; Laguzzi F; Li X; Lyytikainen L-P; Nolte IM; Poveda A; Rauramaa R; Riaz M; Rueedi R; Shu X-O; Snieder H; Sofer T; Takeuchi F; Verweij N; Ware EB; Weiss S; Yanek LR; Amin N; Arking DE; Arnett DK; Bergmann S; Boerwinkle E; Brody JA; Broeckel U; Brumat M; Burke G; Cabrera CP; Canouil M; Chee ML; Chen Y-DI; Cocca M; Connell J; de Silva HJ; de Vries PS; Eiriksdottir G; Faul JD; Fisher V; Forrester T; Fox EF; Friedlander Y; Gao H; Gigante B; Giulianini F; Gu CC; Gu D; Harris TB; He J; Heikkinen S; Heng C-K; Hunt S; Ikram MA; Irvin MR; Kahonen M; Kavousi M; Khor CC; Kilpelainen TO; Koh W-P; Komulainen P; Kraja AT; Krieger JE; Langefeld CD; Li Y; Liang J; Liewald DCM; Liu C-T; Liu J; Lohman KK; Magi R; McKenzie CA; Meitinger T; Metspalu A; Milaneschi Y; Milani L; Mook-Kanamori DO; Nalls MA; Nelson CP; Norris JM; O'Connell J; Ogunniyi A; Padmanabhan S; Palmer ND; Pedersen NL; Perls T; Peters A; Petersmann A; Peyser PA; Polasek O; Porteous DJ; Raffel LJ; Rice TK; Rotter JI; Rudan I; Rueda-Ochoa O-L; Sabanayagam C; Salako BL; Schreiner PJ; Shikany JM; Sidney SS; Sims M; Sitlani CM; Smith JA; Starr JM; Strauch K; Swertz MA; Teumer A; Tham YC; Uitterlinden AG; Vaidya D; van der Ende MY; Waldenberger M; Wang L; Wang Y-X; Wei W-B; Weir DR; Wen W; Yao J; Yu B; Yu C; Yuan J-M; Zhao W; Zonderman AB; Becker DM; Bowden DW; Deary IJ; Doerr M; Esko T; Freedman BI; Froguel P; Gasparini P; Gieger C; Jonas JB; Kammerer CM; Kato N; Lakka TA; Leander K; Lehtimaki T; Magnusson PKE; Marques-Vidal P; Penninx BWJH; Samani NJ; van der Harst P; Wagenknecht LE; Wu T; Zheng W; Zhu X; Bouchard C; Cooper RS; Correa A; Evans MK; Gudnason V; Hayward C; Horta BL; Kelly TN; Kritchevsky SB; Levy D; Palmas WR; Pereira AC; Province MM; Psaty BM; Ridker PM; Rotimi CN; Tai ES; van Dam RM; van Duijn CM; Wong TY; Rice K; Gauderman WJ; Morrison AC; North KE; Kardia SLR; Caulfield MJ; Elliott P; Munroe PB; Franks PW; Rao DC; Fornage M
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2021;41(5):1777-1788
Plasma Protein Profile of Carotid Artery Atherosclerosis and Atherosclerotic Outcomes Meta-Analyses and Mendelian Randomization Analyses
Lind L; Gigante B; Borne Y; Feldreich T; Leppert J; Hedberg P; Ostgren CJ; Nystrom FH; Sundstrom J; Arnlov J; Baldassarre D; Tremoli E; Veglia F; Hamsten A; O'Donnell CJ; Franceschini N; Orho-Melander M; Nilsson J; Melander O; Engstrom G; Malarstig A
Article: THROMBOSIS AND HAEMOSTASIS. 2021;121(05):584-593
High Thrombin Generation after Acute Ischemic Stroke or Transient Ischemic Attack Is Associated with a Reduced Risk of Recurrence: An Observational Cohort Study
Lundstrom A; Anggardh-Rooth E; Mobarrez F; Thalin C; Gigante B; Laska AC; Wallen H
Article: SCIENTIFIC REPORTS. 2021;11(1):7866
Intake of food rich in saturated fat in relation to subclinical atherosclerosis and potential modulating effects from single genetic variants
Laguzzi F; Maitusong B; Strawbridge RJ; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; Kurl S; Smit AJ; Giral P; Silveira A; Tremoli E; Hamsten A; de Faire U; Gigante B; Leander K
Article: EUROPEAN HEART JOURNAL (EHJ) - CARDIOVASCULAR PHARMACOTHERAPY. 2021;7(2):125-140
Antithrombotic therapy in patients with acute coronary syndrome complicated by cardiogenic shock or out-of-hospital cardiac arrest: a joint position paper from the European Society of Cardiology (ESC) Working Group on Thrombosis, in association with the Acute Cardiovascular Care Association (ACCA) and European Association of Percutaneous Cardiovascular Interventions (EAPCI)
Gorog DA; Price S; Sibbing D; Baumbach A; Capodanno D; Gigante B; Halvorsen S; Huber K; Lettino M; Leonardi S; Morais J; Rubboli A; Siller-Matula JM; Storey RF; Vranckx P; Rocca B
Article: BIOMEDICINES. 2021;9(3):286
The Association between HDL-C and Subclinical Atherosclerosis Depends on CETP Plasma Concentration: Insights from the IMPROVE Study
Colombo GI; Bianconi V; Bonomi A; Simonelli S; Amato M; Frigerio B; Ravani A; Vitali C; Sansaro D; Coggi D; Mannarino MR; Savonen KP; Kurl S; Gigante B; Smit AJ; Giral P; Tremoli E; Calabresi L; Veglia F; Pirro M; Baldassarre D
Article: VASCULAR MEDICINE. 2021;26(1):3-10
Expression of Interleukin 6 signaling receptors in carotid atherosclerosis
Ziegler L; Lundqvist J; Dreij K; Wallen H; de Faire U; Paulsson-Berne G; Hedin U; Matic L; Gigante B
Article: SCIENTIFIC REPORTS. 2021;11(1):632
The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals
Strawbridge RJ; Johnston KJA; Bailey MES; Baldassarre D; Cullen B; Eriksson P; deFaire U; Ferguson A; Gigante B; Giral P; Graham N; Hamsten A; Humphries SE; Kurl S; Lyall DM; Lyall LM; Pell JP; Pirro M; Savonen K; Smit AJ; Tremoli E; Tomainen T-P; Veglia F; Ward J; Sennblad B; Smith DJ
Journal article: HEART LUNG AND CIRCULATION. 2021;30:s277
Biomarkers of Dairy Fat Intake, Incident Cardiovascular Disease, and All-Cause Mortality: A Systematic Review and Meta-analysis
Bhat S; Trieu K; Dai Z; Leander K; Gigante B; Qian F; Korat A; Sun Q; Pan X; Laguzzi F; Cederholm T; de Faire U; Hellénius M; Wu J; Risérus U; Marklund M
Article: GENES. 2020;11(11):E1243-1243
Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease Do Not Associate with Measures of Sub-Clinical Atherosclerosis: Results from the IMPROVE Study
Castaldo L; Laguzzi F; Strawbridge RJ; Baldassarre D; Veglia F; Vigo L; Tremoli E; de Faire U; Eriksson P; Smit AJ; Aubrecht J; Leander K; Pirro M; Giral P; Ritieni A; Di Minno G; Malarstig A; Gigante B
Article: ATHEROSCLEROSIS. 2020;309:39-46
Sex-specific predictors of PCSK9 levels in a European population: The IMPROVE study
Ferri N; Ruscica M; Coggi D; Bonomi A; Amato M; Frigerio B; Sansaro D; Ravani A; Veglia F; Capra N; Lupo MG; Macchi C; Castelnuovo S; Savonen K; Silveira A; Kurl S; Giral P; Pirro M; Strawbridge RJ; Gigante B; Smit AJ; Tremoli E; Colombo GI; Baldassarre D
Article: TRANSLATIONAL STROKE RESEARCH. 2020;11(4):708-719
Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA
Lundstrom A; Mobarrez F; Rooth E; Thalin C; von Arbin M; Henriksson P; Gigante B; Laska A-C; Wallen H
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY: HEART & VASCULATURE. 2020;27:100505
Clinical characteristics and antithrombotic prescription in elderly hospitalized atrial fibrillation patients A cross-sectional analysis of a Swedish single-center clinical cohort
Ehrlinder H; Orsini N; Modig K; Hofman-Bang C; Wallen H; Gigante B
Article: JOURNAL OF STROKE AND CEREBROVASCULAR DISEASES. 2020;29(3):104560
Risk of Ischemic Stroke and Major Bleeding in Patients with Atrial Fibrillation and Cancer
Aspberg S; Yu L; Gigante B; Smedby KE; Singer DE
Article: JOURNAL OF HYPERTENSION. 2020;38(3):387-394
Weight gain and blood pressure
Sundstrom J; Lind L; Lampa E; Angeras O; Bachus E; Bergstrom G; Carlberg B; Engstrom G; Engvall JE; Eriksson M; Gigante B; Hagstrom E; Hjelmgren O; Jansson J-H; Jernberg T; Mannila M; Nystrom FH; Oldgren J; Persson M; Sandstrom A; Swahn E; Soderberg S; Toren K; Ostgren CJ; Rosengren A
Article: ATHEROSCLEROSIS. 2020;295:25-30
The plasma protein profile and cardiovascular risk differ between intima-media thickness of the common carotid artery and the bulb: A meta-analysis and a longitudinal evaluation
Lind L; Gigante B; Borne Y; Malarstig A; Sundstrom J; Arnlov J; Ingelsson E; Baldassarre D; Tremoli E; Veglia F; Hamsten A; Orho-Melander M; Nilsson J; Melander O; Engstrom G
Article: GENES AND IMMUNITY. 2020;21(2):100-108
Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study
Bonomi A; Veglia F; Baldassarre D; Strawbridge RJ; Golabkesh Z; Sennblad B; Leander K; Smit AJ; Giral P; Humphries SE; Tremoli E; Hamsten A; de Faire U; Gigante B; Sirtori CR; Castelnuovo S; Calabresi L; Amato M; Frigerio B; Ravani A; Sansaro D; Coggi D; Tedesco CC; Eriksson P; Silveira A; Laguzzi F; Cooper J; Acharya J; Huttunen K; Rauramaa E; Pekkarinen H; Penttila IM; Torronen J; Rauramaa R; Van Gessel AI; Van Roon AM; Teune GC; Kuipers WD; Bruin M; Nicolai A; Haarsma-Jorritsma P; Mulder DJ; Bilo HJG; Smeets GH; Beaudeux JL; Kahn JF; Carreau V; Kontush A; Karppi J; Nurmi T; Nyyssonen K; Salonen R; Tuomainen TP; Tuomainen J; Kauhanen J; Kurl S; Vaudo G; Alaeddin A; Siepi D; Lupattelli G; Mannarino E
Article: EUROPEAN HEART JOURNAL. 2020;41(1):111-188
2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk.
Mach F; Baigent C; Catapano AL; Koskinas KC; Casula M; Badimon L; Chapman MJ; De Backer GG; Delgado V; Ference BA; Graham IM; Halliday A; Landmesser U; Mihaylova B; Pedersen TR; Riccardi G; Richter DJ; Sabatine MS; Taskinen M-R; Tokgozoglu L; Wiklund O; ESC Scientific Document Group
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2020;27(2):122-129
The predictive role of interleukin 6 trans-signalling in middle-aged men and women at low-intermediate risk of cardiovascular events
Ziegler L; Frumento P; Wallen H; de Faire U; Gigante B
Article: ATHEROSCLEROSIS. 2019;289:1-7
Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study
Velle-Forbord T; Eidlaug M; Debik J; Saether JC; Follestad T; Nauman J; Gigante B; Rosjo H; Omland T; Langaas M; Bye A
Article: HUMAN MOLECULAR GENETICS. 2019;28(15):2615-2633
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Sung YJ; de Las Fuentes L; Winkler TW; Chasman DI; Bentley AR; Kraja AT; Ntalla I; Warren HR; Guo X; Schwander K; Manning AK; Brown MR; Aschard H; Feitosa MF; Franceschini N; Lu Y; Cheng C-Y; Sim X; Vojinovic D; Marten J; Musani SK; Kilpelainen TO; Richard MA; Aslibekyan S; Bartz TM; Dorajoo R; Li C; Liu Y; Rankinen T; Smith AV; Tajuddin SM; Tayo BO; Zhao W; Zhou Y; Matoba N; Sofer T; Alver M; Amini M; Boissel M; Chai JF; Chen X; Divers J; Gandin I; Gao C; Giulianini F; Goel A; Harris SE; Hartwig FP; He M; Horimoto ARVR; Hsu F-C; Jackson AU; Kammerer CM; Kasturiratne A; Komulainen P; Kuehnel B; Leander K; Lee W-J; Lin K-H; Luan J; Lyytikainen L-P; McKenzie CA; Nelson CP; Noordam R; Scott RA; Sheu WHH; Stancakova A; Takeuchi F; van Der Most PJ; Varga TV; Waken RJ; Wang H; Wang Y; Ware EB; Weiss S; Wen W; Yanek LR; Zhang W; Zhao JH; Afaq S; Alfred T; Amin N; Arking DE; Aung T; Barr RG; Bielak LF; Boerwinkle E; Bottinger EP; Braund PS; Brody JA; Broeckel U; Cade B; Campbell A; Canouil M; Chakravarti A; Cocca M; Collins FS; Connell JM; de Mutsert R; de Silva HJ; Doerr M; Duan Q; Eaton CB; Ehret G; Evangelou E; Faul JD; Forouhi NG; Franco OH; Friedlander Y; Gao H; Gigante B; Gu CC; Gupta P; Hagenaars SP; Harris TB; He J; Heikkinen S; Heng C-K; Hofman A; Howard BV; Hunt SC; Irvin MR; Jia Y; Katsuya T; Kaufman J; Kerrison ND; Khor CC; Koh W-P; Koistinen HA; Kooperberg CB; Krieger JE; Kubo M; Kutalik Z; Kuusisto J; Lakka TA; Langefeld CD; Langenberg C; Launer LJ; Lee JH; Lehne B; Levy D; Lewis CE; Li Y; Lim SH; Liu C-T; Liu J; Liu J; Liu Y; Loh M; Lohman KK; Louie T; Magi R; Matsuda K; Meitinger T; Metspalu A; Milani L; Momozawa Y; Mosley THJ; Nalls MA; Nasri U; O'Connell JR; Ogunniyi A; Palmas WR; Palmer ND; Pankow JS; Pedersen NL; Peters A; Peyser PA; Polasek O; Porteous D; Raitakari OT; Renstrom F; Rice TK; Ridker PM; Robino A; Robinson JG; Rose LM; Rudan I; Sabanayagam C; Salako BL; Sandow K; Schmidt CO; Schreiner PJ; Scott WR; Sever P; Sims M; Sitlani CM; Smith BH; Smith JA; Snieder H; Starr JM; Strauch K; Tang H; Taylor KD; Teo YY; Tham YC; Uitterlinden AG; Waldenberger M; Wang L; Wang YX; Wei WB; Wilson G; Wojczynski MK; Xiang Y-B; Yao J; Yu C; Yuan J-M; Zonderman AB; Becker DM; Boehnke M; Bowden DW; Chambers JC; Chen Y-DI; Weir DR; de Faire U; Deary IJ; Esko T; Farrall M; Forrester T; Freedman BI; Froguel P; Gasparini P; Gieger C; Horta BL; Hung Y-J; Jonas JB; Kato N; Kooner JS; Laakso M; Lehtimaki T; Liang K-W; Magnusson PKE; Oldehinkel AJ; Pereira AC; Perls T; Rauramaa R; Redline S; Rettig R; Samani NJ; Scott J; Shu X-O; van Der Harst P; Wagenknecht LE; Wareham NJ; Watkins H; Wickremasinghe AR; Wu T; Kamatani Y; Laurie CC; Bouchard C; Cooper RS; Evans MK; Gudnason V; Hixson J; Kardia SLR; Kritchevsky SB; Psaty BM; van Dam RM; Arnett DK; Mook-Kanamori DO; Fornage M; Fox ER; Hayward C; van Duijn CM; Tai ES; Wong TY; Loos RJF; Reiner AP; Rotimi CN; Bierut LJ; Zhu X; Cupples LA; Province MA; Rotter JI; Franks PW; Rice K; Elliott P; Caulfield MJ; Gauderman WJ; Munroe PB; Rao DC; Morrison AC
Article: CIRCULATION. 2019;139(21):2422-2436
Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies
Marklund M; Wu JHY; Imamura F; Del Gobbo LC; Fretts A; de Goede J; Shi P; Tintle N; Wennberg M; Aslibekyan S; Chen T-A; Otto MCDO; Hirakawa Y; Eriksen HH; Kroeger J; Laguzzi F; Lankinen M; Murphy RA; Prem K; Samieri C; Virtanen J; Wood AC; Wong K; Yang W-S; Zhou X; Baylin A; Boer JMA; Brouwer IA; Campos H; Chaves PHM; Chien K-L; de Faire U; Djousse L; Eiriksdottir G; El-Abbadi N; Forouhi NG; Gaziano JM; Geleijnse JM; Gigante B; Giles G; Guallar E; Gudnason V; Harris T; Harris WS; Helmer C; Hellenius M-L; Hodge A; Hu FB; Jacques PF; Jansson J-H; Kalsbeek A; Khaw K-T; Koh W-P; Laakso M; Leander K; Lin H-J; Lind L; Luben R; Luo J; McKnight B; Mursu J; Ninomiya T; Overvad K; Psaty BM; Rimm E; Schulze MB; Siscovick D; Nielsen MS; Smith AV; Steffen BT; Steffen L; Sun Q; Sundstrom J; Tsai MY; Tunstall-Pedoe H; Uusitupa MIJ; van Dam RM; Veenstra J; Verschuren WMM; Wareham N; Willett W; Woodward M; Yuan J-M; Micha R; Lemaitre RN; Mozaffarian D; Riserus U
Article: SCIENTIFIC REPORTS. 2019;9(1):7339
Genetic variation in CADM2 as a link between psychological traits and obesity
Morris J; Bailey MES; Baldassarre D; Cullen B; de Faire U; Ferguson A; Gigante B; Giral P; Goel A; Graham N; Hamsten A; Humphries SE; Johnston KJA; Lyall DM; Lyall LM; Sennblad B; Silveira A; Smit AJ; Tremoli E; Veglia F; Ward J; Watkins H; Smith DJ; Strawbridge RJ
Article: NATURE GENETICS. 2019;51(4):636-648
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Bentley AR; Sung YJ; Brown MR; Winkler TW; Kraja AT; Ntalla I; Schwander K; Chasman DI; Lim E; Deng X; Guo X; Liu J; Lu Y; Cheng C-Y; Sim X; Vojinovic D; Huffman JE; Musani SK; Li C; Feitosa MF; Richard MA; Noordam R; Baker J; Chen G; Aschard H; Bartz TM; Ding J; Dorajoo R; Manning AK; Rankinen T; Smith AV; Tajuddin SM; Zhao W; Graff M; Alver M; Boissel M; Chai JF; Chen X; Divers J; Evangelou E; Gao C; Goel A; Hagemeijer Y; Harris SE; Hartwig FP; He M; Horimoto ARVR; Hsu F-C; Hung Y-J; Jackson AU; Kasturiratne A; Komulainen P; Kuehnel B; Leander K; Lin K-H; Luan J; Lyytikainen L-P; Matoba N; Nolte IM; Pietzner M; Prins B; Riaz M; Robino A; Said MA; Schupf N; Scott RA; Sofer T; Stancakova A; Takeuchi F; Tayo BO; van der Most PJ; Varga TV; Wang T-D; Wang Y; Ware EB; Wen W; Xiang Y-B; Yanek LR; Zhang W; Zhao JH; Adeyemo A; Afaq S; Amin N; Amini M; Arking DE; Arzumanyan Z; Aung T; Ballantyne C; Barr RG; Bielak LF; Boerwinkle E; Bottinger EP; Broeckel U; Brown M; Cade BE; Campbell A; Canouil M; Charumathi S; Chen Y-DI; Christensen K; Concas MP; Connell JM; de las Fuentes L; de Silva HJ; de Vries PS; Doumatey A; Duan Q; Eaton CB; Eppinga RN; Faul JD; Floyd JS; Forouhi NG; Forrester T; Friedlander Y; Gandin I; Gao H; Ghanbari M; Gharib SA; Gigante B; Giulianini F; Grabe HJ; Gu CC; Harris TB; Heikkinen S; Heng C-K; Hirata M; Hixson JE; Ikram MA; Jia Y; Joehanes R; Johnson C; Jonas JB; Justice AE; Katsuya T; Khor CC; Kilpelainen TO; Koh W-P; Kolcic I; Kooperberg C; Krieger JE; Kritchevsky SB; Kubo M; Kuusisto J; Lakka TA; Langefeld CD; Langenberg C; Launer LJ; Lehne B; Lewis CE; Li Y; Liang J; Lin S; Liu C-T; Liu J; Liu K; Loh M; Lohman KK; Louie T; Luzzi A; Magi R; Mahajan A; Manichaikul AW; McKenzie CA; Meitinger T; Metspalu A; Milaneschi Y; Milani L; Mohlke KL; Momozawa Y; Morris AP; Murray AD; Nalls MA; Nauck M; Nelson CP; North KE; O'Connell JR; Palmer ND; Papanicolau GJ; Pedersen NL; Peters A; Peyser PA; Polasek O; Poulter N; Raitakari OT; Reiner AP; Renstrom F; Rice TK; Rich SS; Robinson JG; Rose LM; Rosendaal FR; Rudan I; Schmidt CO; Schreiner PJ; Scott WR; Sever P; Shi Y; Sidney S; Sims M; Smith JA; Snieder H; Starr JM; Strauch K; Stringham HM; Tan NYQ; Tang H; Taylor KD; Teo YY; Tham YC; Tiemeier H; Turner ST; Uitterlinden AG; van Heemst D; Waldenberger M; Wang H; Wang L; Wang L; Wei WB; Williams CA; Wilson GS; Wojczynski MK; Yao J; Young K; Yu C; Yuan J-M; Zhou J; Zonderman AB; Becker DM; Boehnke M; Bowden DW; Chambers JC; Cooper RS; de Faire U; Deary IJ; Elliott P; Esko T; Farrall M; Franks PW; Freedman BI; Froguel P; Gasparini P; Gieger C; Horta BL; Juang J-MJ; Kamatani Y; Kammerer CM; Kato N; Kooner JS; Laakso M; Laurie CC; Lee I-T; Lehtimaki T; Magnusson PKE; Oldehinkel AJ; Penninx BWJH; Pereira AC; Rauramaa R; Redline S; Samani NJ; Scott J; Shu X-O; van der Harst P; Wagenknecht LE; Wang J-S; Wang YX; Wareham NJ; Watkins H; Weir DR; Wickremasinghe AR; Wu T; Zeggini E; Zheng W; Bouchard C; Evans MK; Gudnason V; Kardia SLR; Liu Y; Psaty BM; Ridker PM; van Dam RM; Mook-Kanamori DO; Fornage M; Province MA; Kelly TN; Fox ER; Hayward C; van Duijn CM; Tai ES; Wong TY; Loos RJF; Franceschini N; Rotter JI; Zhu X; Bierut LJ; Gauderman WJ; Rice K; Munroe PB; Morrison AC; Rao DC; Rotimi CN; Cupples LA
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2019;12(4):e002471
Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events A GENIUS-CHD Study of Individual Participant Data
Patel RS; Schmidt AF; Tragante V; McCubrey RO; Holmes MV; Howe LJ; Direk K; Akerblom A; Leander K; Virani SS; Kaminski KA; Muehlschlegel JD; Dube M-P; Allayee H; Almgren P; Alver M; Baranova EV; Behlouli H; Boeckx B; Braund PS; Breitling LP; Delgado G; Duarte NE; Dufresne L; Eriksson N; Foco L; Gijsberts CM; Gong Y; Hartiala J; Heydarpour M; Hubacek JA; Kleber M; Kofink D; Kuukasjarvi P; Lee V-V; Leiherer A; Lenzini PA; Levin D; Lyytikainen L-P; Martinelli N; Mons U; Nelson CP; Nikus K; Pilbrow AP; Ploski R; Sun YV; Tanck MWT; Tang WHW; Trompet S; van der Laan SW; van Setten J; Vilmundarson RO; Anselmi CV; Vlachopoulou E; Boerwinkle E; Briguori C; Carlquist JF; Carruthers KF; Casu G; Deanfield J; Deloukas P; Dudbridge F; Fitzpatrick N; Gigante B; James S; Lokki M-L; Lotufo PA; Marziliano N; Mordi IR; Muhlestein JB; Cheh CN; Pitha J; Saely CH; Samman-Tahhan A; Sandesara PB; Teren A; Timmis A; Van de Werf F; Wauters E; Wilde AAM; Ford I; Stott DJ; Algra A; Andreassi MG; Ardissino D; Arsenault BJ; Ballantyne CM; Bergmeijer TO; Bezzina CR; Body SC; Bogaty P; de Borst GJ; Brenner H; Burkhardt R; Carpeggiani C; Condorelli G; Cooper-DeHoff RM; Cresci S; de Faire U; Doughty RN; Drexel H; Engert JC; Fox KAA; Girelli D; Hagstrom E; Hazen SL; Held C; Hemingway H; Hoefer IE; Hovingh GK; Johnson JA; De Jong PA; Jukema JW; Kaczor MP; Kahonen M; Kettner J; Kiliszek M; Klungel OH; Lagerqvist B; Lambrechts D; Laurikka JO; Lehtimaki T; Lindholm D; Mahmoodi BK; Maitland-van der Zee AH; McPherson R; Melander O; Metspalu A; Pepinski W; Olivieri O; Opolski G; Palmer CN; Pasterkamp G; Pepine CJ; Pereira AC; Note L; Quyyumi AA; Richards AM; Sanak M; Scholz M; Siegbahn A; Sinisalo J; Smith JG; Spertus JA; Stewart AFR; Szczeklik W; Szpakowicz A; ten Berg JM; Thanassoulis G; Thieiy J; van der Graaf Y; Visseren FLJ; Waltenberger J; Van der Harst P; Tardif J-C; Sattar N; Lang CC; Pare G; Brophy JM; Anderson JL; Maerz W; Wallentin L; Cameron VA; Horne BD; Samani NJ; Hingorani AD; Asselbergs FW
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2019;12(4):e002470
Subsequent Event Risk in Individuals With Established Coronary Heart Disease Design and Rationale of the GENIUS-CHD Consortium
Patel RS; Tragante V; Schmidt AF; McCubrey RO; Holmes MV; Howe LJ; Direk K; Akerblom A; Leander K; Virani SS; Kaminski KA; Muehlschlegel JD; Allayee H; Almgren P; Alver M; Baranova EV; Behloui H; Boeckx B; Braund PS; Breitling LP; Delgado G; Duarte NE; Dube M-P; Dufresne L; Eriksson N; Foco L; Scholz M; Gijsberts CM; Glinge C; Gong Y; Hartiala J; Heydarpour M; Hubacek JA; Kleber M; Kofink D; Kotti S; Kuukasjarvi P; Lee V-V; Leiherer A; Lenzini PA; Levin D; Lyytikainen L-P; Martinelli N; Mons U; Nelson CP; Nikus K; Pilbrow AP; Ploski R; Sun YV; Tanck MWT; Tang WHW; Trompet S; van der Laan SW; Van Setten J; Vilmundarson RO; Anselmi CV; Vlachopoulou E; Al Ali L; Boerwinkle E; Briguori C; Carlquist JF; Carruthers KF; Casu G; Deanfield J; Deloukas P; Dudbridge F; Engstrom T; Fitzpatrick N; Fox K; Gigante B; James S; Lokki M-L; Lotufo PA; Marziliano N; Mordi IR; Muhlestein JB; Newton-Cheh C; Pitha J; Saely CH; Samman-Tahhan A; Sandesara PB; Teren A; Timmis A; Van de Werf F; Wauters E; Wilde AAM; Ford I; Stott DJ; Algra A; Andreassi MG; Ardissino D; Arsenault BJ; Ballantyne CM; Bergmeijer TO; Bezzina CR; Body SC; Boersma EH; Bogaty P; Bots ML; Brenner H; Brugts JJ; Burkhardt R; Carpeggiani C; Condorelli G; Cooper-DeHoff RM; Cresci S; Danchin N; de Faire U; Doughty RN; Drexel H; Engert JC; Fox KAA; Girelli D; Grobbee DE; Hagstrom E; Hazen SL; Held C; Hemingway H; Hoefer IE; Hovingh GK; Jabbari R; Johnson JA; Jukema JW; Kaczor MP; Kahonen M; Kettner J; Kiliszek M; Klungel OH; Lagerqvist B; Lambrechts D; Laurikka JO; Lehtimaki T; Lindholm D; Mahmoodi BK; Maitland-van der Zee AH; McPherson R; Melander O; Metspalu A; Niemcunowicz-Janica A; Olivieri O; Opolski G; Palmer CN; Pasterkamp G; Pepine CJ; Pereira AC; Pilote L; Quyyumi AA; Richards AM; Sanak M; Siegbahn A; Simon T; Sinisalo J; Smith JG; Spertus JA; Stender S; Stewart AFR; Szczeklik W; Szpakowicz A; Tardif J-C; ten Berg JM; Tfelt-Hansen J; Thanassoulis G; Thiery J; Torp-Pedersen C; van der Graaf Y; Visseren FLJ; Waltenberger J; Weeke PE; Van der Harst P; Lang CC; Sattar N; Cameron VA; Anderson JL; Brophy JM; Pare G; Horne BD; Marz W; Wallentin L; Samani NJ; Hingorani AD; Asselbergs FW
Article: BMC CARDIOVASCULAR DISORDERS. 2019;19(1):34
Serum IL8 is not associated with cardiovascular events but with all-cause mortality
Velasquez IM; Gajulapuri A; Leander K; Berglund A; de Faire U; Gigante B
Article: CARDIOVASCULAR RESEARCH (CVR). 2019;115(1):213-221
Interleukin 6 trans-signalling and risk of future cardiovascular events
Ziegler L; Gajulapuri A; Frumento P; Bonomi A; Wallen H; de Faire U; Rose-John S; Gigante B
Article: CLINICAL NUTRITION. 2018;37(6):2001-2010
Circulating fatty acids in relation to alcohol consumption: Cross-sectional results from a cohort of 60-year-old men and women
Laguzzi F; Riserus U; Marklund M; Vikstrom M; Sjogren R; Gigante B; Alsharari ZD; Hellenius M-L; Cederholm T; Frumento P; de Faire U; Leander K
Journal article: EUROPEAN HEART JOURNAL. 2018;39(suppl_1):ehy566.p6344
P6344Pulmonary embolism is a possible risk factor for ischemic stroke before 65 years of age in patients with atrial fibrillation
Aspberg S; Smedback K; Gigante B; Yu L; Chang Y; Singer DE
Article: JOURNAL OF CLINICAL ONCOLOGY. 2018;36(22):2288-2296
Cardiac Structure Injury After Radiotherapy for Breast Cancer: Cross-Sectional Study With Individual Patient Data
Taylor C; McGale P; Bronnum D; Correa C; Cutter D; Duane FK; Gigante B; Jensen M-B; Lorenzen E; Rahimi K; Wang Z; Darby SC; Hall P; Ewertz M
Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2018;71(4):240-247
Effects of Angiotensin-Converting Enzyme Inhibition and Alpha 1-Adrenergic Receptor Blockade on Inflammation and Hemostasis in Human Hypertension
Ekholm M; Jekell A; Wallen NH; Gigante B; Kahan T
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2018;102(3):375-400
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
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Article: CARDIOVASCULAR PATHOLOGY. 2018;32:32-37
Comorbidities in relation to fatali of first myocardial infarction
Quintana HK; Janszky I; Kanar A; Gigante B; Druid H; Ahlbom A; de Faire U; Hallqyist J; Leander K
Article: PLOS ONE. 2018;13(6):e0198166
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
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Article: DIABETES. 2017;66(11):db161253-2902
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
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Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(6):067007
Exposure to Traffic-Related Air Pollution and Serum Inflammatory Cytokines in Children
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Article: NATURE COMMUNICATIONS. 2017;8:14977
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IgM antibodies to oxidized phosphatidylserine as protection markers in cardiovascular disease among 60-year olds
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Article: PLOS ONE. 2017;12(1):e0170684
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Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(12):e004415
Human IgM Antibodies to Malondialdehyde Conjugated With Albumin Are Negatively Associated With Cardiovascular Disease Among 60-Year-Olds
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Article: NATURE GENETICS. 2016;48(10):1171-1184
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Article: JOURNAL OF HUMAN NUTRITION AND DIETETICS. 2016;29(3):325-337
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Article: CIRCULATION: HEART FAILURE. 2016;9(4):e002855
Healthy Lifestyle and Risk of Heart Failure: Results From 2 Prospective Cohort Studies
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Article: EUROPEAN JOURNAL OF HEART FAILURE. 2016;18(3):253-259
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Article: NATURE GENETICS. 2015;47(12):1415-1425
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
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Article: ANNALS OF MEDICINE. 2015;47(8):679-686
Pulse pressure is not an independent predictor of incident atrial fibrillation in 60-year-old men and women
Miedel C; Leander K; de Faire U; Gigante B
Article: ATHEROSCLEROSIS. 2015;243(1):93-98
A Mediterranean diet and risk of myocardial infarction, heart failure and stroke: A population-based cohort study
Tektonidis TG; Akesson A; Gigante B; Wolk A; Larsson SC
Article: JOURNAL OF STROKE AND CEREBROVASCULAR DISEASES. 2015;24(10):2348-2357
Clopidogrel Resistance after Minor Ischemic Stroke or Transient Ischemic Attack is Associated with Radiological Cerebral Small-Vessel Disease
Lundstrom A; Wallen H; von Arbin M; Jorneskog G; Gigante B; Dembrower KH; Laurencikas E; Laska AC
Article: PLOS GENETICS. 2015;11(10):e1005378
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
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Article: CIRCULATION. 2015;132(7):586-594
Polyunsaturated Fat Intake Estimated by Circulating Biomarkers and Risk of Cardiovascular Disease and All-Cause Mortality in a Population-Based Cohort of 60-Year-Old Men and Women
Marklund M; Leander K; Vikstrom M; Laguzzi F; Gigante B; Sjogren P; Cederholm T; de Faire U; Hellenius M-L; Riserus U
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2015;4(8):e001853
Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease
Persson J; Strawbridge RJ; McLeod O; Gertow K; Silveira A; Baldassarre D; Van Zuydam N; Shah S; Fava C; Gustafsson S; Veglia F; Sennblad B; Larsson M; Sabater-Lleal M; Leander K; Gigante B; Tabak A; Kivimaki M; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Humphries SE; Tremoli E; de Faire U; Lind L; Ingelsson E; Hedblad B; Melander O; Kumari M; Hingorani A; Morris AD; Palmer CNA; Lundman P; Ohrvik J; Soderberg S
Article: ATHEROSCLEROSIS. 2015;240(2):477-481
Circulating levels of interleukin 6 soluble receptor and its natural antagonist, sgp130, and the risk of myocardial infarction
Velasquez IM; Golabkesh Z; Kallberg H; Leander K; de Faire U; Gigante B
Article: MENOPAUSE. 2015;22(6):598-606
Does menopausal hormone therapy reduce myocardial infarction risk if initiated early after menopause? A population-based case-control study
Carrasquilla GD; Berglund A; Gigante B; Landgren B-M; de Faire U; Hallqvist J; Leander K
Article: CYTOKINE. 2015;72(2):178-184
Duffy antigen receptor genetic variant and the association with Interleukin 8 levels
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Article: ATHEROSCLEROSIS. 2015;239(1):125-130
Plasma IL-5 concentration and subclinical carotid atherosclerosis
Silveira A; McLeod O; Strawbridge RJ; Gertow K; Sennblad B; Baldassarre D; Veglia F; Deleskog A; Persson J; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Gustafsson S; Soderberg S; Ohrvik J; Humphries SE; Tremoli E; de Faire U; Hamsten A
Article: NATURE. 2015;518(7538):187-196
New genetic loci link adipose and insulin biology to body fat distribution
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Article: NATURE. 2015;518(7538):197-206
Genetic studies of body mass index yield new insights for obesity biology
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Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men
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Long-Term Exposure to Ambient Air Pollution and Incidence of Cerebrovascular Events: Results from 11 European Cohorts within the ESCAPE Project
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A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness)
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Article: ATHEROSCLEROSIS. 2014;232(1):242-248
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Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2013;33(12):2909-2914
Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia
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Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2013;33(11):2633-2638
Serum 25-Hydroxyvitamin D Concentration in Subclinical Carotid Atherosclerosis
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Article: NATURE GENETICS. 2013;45(11):1345-1352
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Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2013;168(2):946-952
Seven modifiable lifestyle factors predict reduced risk for ischemic cardiovascular disease and all-cause mortality regardless of body mass index: A cohort study
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Article: PLOS GENETICS. 2013;9(6):e1003500
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
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Article: NEW ENGLAND JOURNAL OF MEDICINE. 2013;368(11):987-998
Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer
Darby SC; Ewertz M; McGale P; Bennet AM; Blom-Goldman U; Bronnum D; Correa C; Cutter D; Gagliardi G; Gigante B; Jensen M-B; Nisbet A; Peto R; Rahimi K; Taylor C; Hall P
Article: ATHEROSCLEROSIS. 2013;226(2):440-446
A gene-centric study of common carotid artery remodelling
Harrison SC; Zabaneh D; Asselbergs FW; Drenos F; Jones GT; Shah S; Gertow K; Sennblad B; Strawbridge RJ; Gigante B; Holewijn S; De Graaf J; Vermeulen S; Folkersen L; van Rij AM; Baldassarre D; Veglia F; Talmud PJ; Deanfield JE; Agu O; Kivimaki M; Kumari M; Bown MJ; Nyyssonen K; Rauramaa R; Smit AJ; Franco-Cereceda A; Giral P; Mannarino E; Silveira A; Syvanen A-C; de Borst GJ; van der Graaf Y; de Faire U; Baas AF; Blankensteijn JD; Wareham NJ; Fowkes G; Tzoulaki I; Price JF; Tremoli E; Hingorani AD; Eriksson P; Hamsten A; Humphries SE
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2013;6(1):63-72
Causal Relevance of Blood Lipid Fractions in the Development of Carotid Atherosclerosis Mendelian Randomization Analysis
Shah S; Casas J-P; Drenos F; Whittaker J; Deanfield J; Swerdlow DI; Holmes MV; Kivimaki M; Langenberg C; Wareham N; Gertow K; Sennblad B; Strawbridge RJ; Baldassarre D; Veglia F; Tremoli E; Gigante B; de Faire U; Kumari M; Talmud PJ; Hamsten A; Humphries SE; Hingorani AD
Article: BMC CARDIOVASCULAR DISORDERS. 2013;13:1
Low levels of IgM antibodies to oxidized cardiolipin increase and high levels decrease risk of cardiovascular disease among 60-year olds: a prospective study
Su J; Hua X; Vikstrom M; Leander K; Gigante B; Hellenius M-L; de Faire U; Frostegard J
Article: PLOS ONE. 2013;8(4):e61763
The Risk of Type 2 Diabetes in Men Is Synergistically Affected by Parental History of Diabetes and Overweight
Wikner C; Gigante B; Hellenius M-L; de Faire U; Leander K
Article: NATURE GENETICS. 2013;45(1):25-33
Large-scale association analysis identifies new risk loci for coronary artery disease.
CARDIoGRAMplusC4D Consortium; Deloukas P; Kanoni S; Willenborg C; Farrall M; Assimes TL; Thompson JR; Ingelsson E; Saleheen D; Erdmann J; Goldstein BA; Stirrups K; König IR; Cazier J-B; Johansson A; Hall AS; Lee J-Y; Willer CJ; Chambers JC; Esko T; Folkersen L; Goel A; Grundberg E; Havulinna AS; Ho WK; Hopewell JC; Eriksson N; Kleber ME; Kristiansson K; Lundmark P; Lyytikäinen L-P; Rafelt S; Shungin D; Strawbridge RJ; Thorleifsson G; Tikkanen E; Van Zuydam N; Voight BF; Waite LL; Zhang W; Ziegler A; Absher D; Altshuler D; Balmforth AJ; Barroso I; Braund PS; Burgdorf C; Claudi-Boehm S; Cox D; Dimitriou M; Do R; DIAGRAM Consortium; CARDIOGENICS Consortium; Doney ASF; El Mokhtari N; Eriksson P; Fischer K; Fontanillas P; Franco-Cereceda A; Gigante B; Groop L; Gustafsson S; Hager J; Hallmans G; Han B-G; Hunt SE; Kang HM; Illig T; Kessler T; Knowles JW; Kolovou G; Kuusisto J; Langenberg C; Langford C; Leander K; Lokki M-L; Lundmark A; McCarthy MI; Meisinger C; Melander O; Mihailov E; Maouche S; Morris AD; Müller-Nurasyid M; MuTHER Consortium; Nikus K; Peden JF; Rayner NW; Rasheed A; Rosinger S; Rubin D; Rumpf MP; Schäfer A; Sivananthan M; Song C; Stewart AFR; Tan S-T; Thorgeirsson G; van der Schoot CE; Wagner PJ; Wellcome Trust Case Control Consortium; Wells GA; Wild PS; Yang T-P; Amouyel P; Arveiler D; Basart H; Boehnke M; Boerwinkle E; Brambilla P; Cambien F; Cupples AL; de Faire U; Dehghan A; Diemert P; Epstein SE; Evans A; Ferrario MM; Ferrières J; Gauguier D; Go AS; Goodall AH; Gudnason V; Hazen SL; Holm H; Iribarren C; Jang Y; Kähönen M; Kee F; Kim H-S; Klopp N; Koenig W; Kratzer W; Kuulasmaa K; Laakso M; Laaksonen R; Lee J-Y; Lind L; Ouwehand WH; Parish S; Park JE; Pedersen NL; Peters A; Quertermous T; Rader DJ; Salomaa V; Schadt E; Shah SH; Sinisalo J; Stark K; Stefansson K; Trégouët D-A; Virtamo J; Wallentin L; Wareham N; Zimmermann ME; Nieminen MS; Hengstenberg C; Sandhu MS; Pastinen T; Syvänen A-C; Hovingh GK; Dedoussis G; Franks PW; Lehtimäki T; Metspalu A; Zalloua PA; Siegbahn A; Schreiber S; Ripatti S; Blankenberg SS; Perola M; Clarke R; Boehm BO; O'Donnell C; Reilly MP; März W; Collins R; Kathiresan S; Hamsten A; Kooner JS; Thorsteinsdottir U; Danesh J; Palmer CNA; Roberts R; Watkins H; Schunkert H; Samani NJ
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2012;5(6):656-665
Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk
Gertow K; Sennblad B; Strawbridge RJ; Oehrvik J; Zabaneh D; Shah S; Veglia F; Fava C; Kavousi M; McLachlan S; Kivimaeki M; Bolton JL; Folkersen L; Gigante B; Leander K; Vikstrom M; Larsson M; Silveira A; Deanfield J; Voight BF; Fontanillas P; Sabater-Lleal M; Colombo GI; Kumari M; Langenberg C; Wareham NJ; Uitterlinden AG; Gabrielsen A; Hedin U; Franco-Cereceda A; Nyyssonen K; Rauramaa R; Tuomainen T-P; Savonen K; Smit AJ; Giral P; Mannarino E; Robertson CM; Talmud PJ; Hedblad B; Hofman A; Erdmann J; Reilly MP; O'Donnell CJ; Farrall M; Clarke R; Franzosi MG; Seedorf U; Syvanen A-C; Hansson GK; Eriksson P; Samani NJ; Watkins H; Price JF; Hingorani AD; Melander O; Witteman JCM; Baldassarre D; Tremoli E; de Faire U; Humphries SE; Hamsten A
Article: BMC CARDIOVASCULAR DISORDERS. 2012;12:90
Chromosome 1p13 genetic variants antagonize the risk of myocardial infarction associated with high ApoB serum levels
Gigante B; Leander K; Vikstrom M; Ye S; de Faire U
Article: NATURE GENETICS. 2012;44(9):981-990
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Morris AP; Voight BF; Teslovich TM; Ferreira T; Segre AV; Steinthorsdottir V; Strawbridge RJ; Khan H; Grallert H; Mahajan A; Prokopenko I; Kang HM; Dina C; Esko T; Fraser RM; Kanoni S; Kumar A; Lagou V; Langenberg C; Luan J; Lindgren CM; Mueller-Nurasyid M; Pechlivanis S; Rayner NW; Scott LJ; Wiltshire S; Yengo L; Kinnunen L; Rossin EJ; Raychaudhuri S; Johnson AD; Dimas AS; Loos RJF; Vedantam S; Chen H; Florez JC; Fox C; Liu C-T; Rybin D; Couper DJ; Kao WHL; Li M; Cornelis MC; Kraft P; Sun Q; van Dam RM; Stringham HM; Chines PS; Fischer K; Fontanillas P; Holmen OL; Hunt SE; Jackson AU; Kong A; Lawrence R; Meyer J; Perry JRB; Platou CGP; Potter S; Rehnberg E; Robertson N; Sivapalaratnam S; Stancakova A; Stirrups K; Thorleifsson G; Tikkanen E; Wood AR; Almgren P; Atalay M; Benediktsson R; Bonnycastle LL; Burtt N; Carey J; Charpentier G; Crenshaw AT; Doney ASF; Dorkhan M; Edkins S; Emilsson V; Eury E; Forsen T; Gertow K; Gigante B; Grant GB; Groves CJ; Guiducci C; Herder C; Hreidarsson AB; Hui J; James A; Jonsson A; Rathmann W; Klopp N; Kravic J; Krjutskov K; Langford C; Leander K; Lindholm E; Lobbens S; Mannisto S; Mirza G; Muehleisen TW; Musk B; Parkin M; Rallidis L; Saramies J; Sennblad B; Shah S; Sigurdsson G; Silveira A; Steinbach G; Thorand B; Trakalo J; Veglia F; Wennauer R; Winckler W; Zabaneh D; Campbell H; van Duijn C; Uitterlinden AG; Hofman A; Sijbrands E; Abecasis GR; Owen KR; Zeggini E; Trip MD; Forouhi NG; Syvanen A-C; Eriksson JG; Peltonen L; Noethen MM; Balkau B; Palmer CNA; Lyssenko V; Tuomi T; Isomaa B; Hunter DJ; Qi L; Shuldiner AR; Roden M; Barroso I; Wilsgaard T; Beilby J; Hovingh K; Price JF; Wilson JF; Rauramaa R; Lakka TA; Lind L; Dedoussis G; Njolstad I; Pedersen NL; Khaw K-T; Wareham NJ; Keinanen-Kiukaanniemi SM; Saaristo TE; Korpi-Hyovalti E; Saltevo J; Laakso M; Kuusisto J; Metspalu A; Collins FS; Mohlke KL; Bergman RN; Tuomilehto J; Boehm BO; Gieger C; Hveem K; Cauchi S; Froguel P; Baldassarre D; Tremoli E; Humphries SE; Saleheen D; Danesh J; Ingelsson E; Ripatti S; Salomaa V; Erbel R; Joeckel K-H; Moebus S; Peters A; Illig T; de Faire U; Hamsten A; Morris AD; Donnelly PJ; Frayling TM; Hattersley AT; Boerwinkle E; Melander O; Kathiresan S; Nilsson PM; Deloukas P; Thorsteinsdottir U; Groop LC; Stefansson K; Hu F; Pankow JS; Dupuis J; Meigs JB; Altshuler D; Boehnke M; McCarthy MI
Article: NATURE GENETICS. 2012;44(9):991-1005
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Scott RA; Lagou V; Welch RP; Wheeler E; Montasser ME; Luan J; Maegi R; Strawbridge RJ; Rehnberg E; Gustafsson S; Kanoni S; Rasmussen-Torvik LJ; Yengo L; Lecoeur C; Shungin D; Sanna S; Sidore C; Johnson PCD; Jukema JW; Johnson T; Mahajan A; Verweij N; Thorleifsson G; Hottenga J-J; Shah S; Smith AV; Sennblad B; Gieger C; Salo P; Perola M; Timpson NJ; Evans DM; St Pourcain B; Wu Y; Andrews JS; Hui J; Bielak LF; Zhao W; Horikoshi M; Navarro P; Isaacs A; O'Connell JR; Stirrups K; Vitart V; Hayward C; Esko T; Mihailov E; Fraser RM; Fall T; Voight BF; Raychaudhuri S; Chen H; Lindgren CM; Morris AP; Rayner NW; Robertson N; Rybin D; Liu C-T; Beckmann JS; Willems SM; Chines PS; Jackson AU; Kang HM; Stringham HM; Song K; Tanaka T; Peden JF; Goel A; Hicks AA; An P; Mueller-Nurasyid M; Franco-Cereceda A; Folkersen L; Marullo L; Jansen H; Oldehinkel AJ; Bruinenberg M; Pankow JS; North KE; Forouhi NG; Loos RJF; Edkins S; Varga TV; Hallmans G; Oksa H; Antonella M; Nagaraja R; Trompet S; Ford I; Bakker SJL; Kong A; Kumari M; Gigante B; Herder C; Munroe PB; Caulfield M; Antti J; Mangino M; Small K; Miljkovic I; Liu Y; Atalay M; Kiess W; James AL; Rivadeneira F; Uitterlinden AG; Palmer CNA; Doney ASF; Willemsen G; Smit JH; Campbell S; Polasek O; Bonnycastle LL; Hercberg S; Dimitriou M; Bolton JL; Fowkes GR; Kovacs P; Lindstrom J; Zemunik T; Bandinelli S; Wild SH; Basart HV; Rathmann W; Grallert H; Maerz W; Kleber ME; Boehm BO; Peters A; Pramstaller PP; Province MA; Borecki IB; Hastie ND; Rudan I; Campbell H; Watkins H; Farrall M; Stumvoll M; Ferrucci L; Waterworth DM; Bergman RN; Collins FS; Tuomilehto J; Watanabe RM; de Geus EJC; Penninx BW; Hofman A; Oostra BA; Psaty BM; Vollenweider P; Wilson JF; Wright AF; Hovingh GK; Metspalu A; Uusitupa M; Magnusson PKE; Kyvik KO; Kaprio J; Price JF; Dedoussis GV; Deloukas P; Meneton P; Lind L; Boehnke M; Shuldiner AR; van Duijn CM; Morris AD; Toenjes A; Peyser PA; Beilby JP; Koerner A; Kuusisto J; Laakso M; Bornstein SR; Schwarz PEH; Lakka TA; Rauramaa R; Adair LS; Smith GD; Spector TD; Illig T; de Faire U; Hamsten A; Gudnason V; Kivimaki M; Hingorani A; Keinanen-Kiukaanniemi SM; Saaristo TE; Boomsma DI; Stefansson K; van der Harst P; Dupuis J; Pedersen NL; Sattar N; Harris TB; Cucca F; Ripatti S; Salomaa V; Mohlke KL; Balkau B; Froguel P; Pouta A; Jarvelin M-R; Wareham NJ; Bouatia-Naji N; McCarthy MI; Franks PW; Meigs JB; Teslovich TM; Florez JC; Langenberg C; Ingelsson E; Prokopenko I; Barroso I
Article: HEART. 2012;98(16):1242-1245
Elevated ApoB serum levels strongly predict early cardiovascular events
Gigante B; Leander K; Vikstrom M; Frumento P; Carlsson AC; Bottai M; de Faire U
Article: THE LANCET. 2012;380(9841):572-580
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
Voight BF; Peloso GM; Orho-Melander M; Frikke-Schmidt R; Barbalic M; Jensen MK; Hindy G; Holm H; Ding EL; Johnson T; Schunkert H; Samani NJ; Clarke R; Hopewell JC; Thompson JF; Li M; Thorleifsson G; Newton-Cheh C; Musunuru K; Pirruccello JP; Saleheen D; Chen L; Stewart AFR; Schillert A; Thorsteinsdottir U; Thorgeirsson G; Anand S; Engert JC; Morgan T; Spertus J; Stoll M; Berger K; Martinelli N; Girelli D; McKeown PP; Patterson CC; Epstein SE; Devaney J; Burnett M-S; Mooser V; Ripatti S; Surakka I; Nieminen MS; Sinisalo J; Lokki M-L; Perola M; Havulinna A; de Faire U; Gigante B; Ingelsson E; Zeller T; Wild P; de Bakker PIW; Klungel OH; Maitland-van der Zee A-H; Peters BJM; de Boer A; Grobbee DE; Kamphuisen PW; Deneer VHM; Elbers CC; Onland-Moret NC; Hofker MH; Wijmenga C; Verschuren WMM; Boer JMA; van der Schouw YT; Rasheed A; Frossard P; Demissie S; Willer C; Do R; Ordovas JM; Abecasis GR; Boehnke M; Mohlke KL; Daly MJ; Guiducci C; Burtt NP; Surti A; Gonzalez E; Purcell S; Gabriel S; Marrugat J; Peden J; Erdmann J; Diemert P; Willenborg C; Koenig IR; Fischer M; Hengstenberg C; Ziegler A; Buysschaert I; Lambrechts D; Van de Werf F; Fox KA; El Mokhtari NE; Rubin D; Schrezenmeir J; Schreiber S; Schaefer A; Danesh J; Blankenberg S; Roberts R; McPherson R; Watkins H; Hall AS; Overvad K; Rimm E; Boerwinkle E; Tybjaerg-Hansen A; Cupples LA; Reilly MP; Melander O; Mannucci PM; Ardissino D; Siscovick D; Elosua R; Stefansson K; O'Donnell CJ; Salomaa V; Rader DJ; Peltonen L; Schwartz SM; Altshuler D; Kathiresan S
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2012;32(6):1526-1534
Common and Low-Frequency Genetic Variants in the PCSK9 Locus Influence Circulating PCSK9 Levels
Chernogubova E; Strawbridge R; Mahdessian H; Malarstig A; Krapivner S; Gigante B; Hellenius M-L; de Faire U; Franco-Cereceda A; Syvaenen A-C; Troutt JS; Konrad RJ; Eriksson P; Hamsten A; van 't Hooft FM
Article: NATURE GENETICS. 2012;44(6):659-669
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Manning AK; Hivert M-F; Scott RA; Grimsby JL; Bouatia-Naji N; Chen H; Rybin D; Liu C-T; Bielak LF; Prokopenko I; Amin N; Barnes D; Cadby G; Hottenga J-J; Ingelsson E; Jackson AU; Johnson T; Kanoni S; Ladenvall C; Lagou V; Lahti J; Lecoeur C; Liu Y; Martinez-Larrad MT; Montasser ME; Navarro P; Perry JRB; Rasmussen-Torvik LJ; Salo P; Sattar N; Shungin D; Strawbridge RJ; Tanaka T; van Duijn CM; An P; de Andrade M; Andrews JS; Aspelund T; Atalay M; Aulchenko Y; Balkau B; Bandinelli S; Beckmann JS; Beilby JP; Bellis C; Bergman RN; Blangero J; Boban M; Boehnke M; Boerwinkle E; Bonnycastle LL; Boomsma DI; Borecki IB; Boettcher Y; Bouchard C; Brunner E; Budimir D; Campbell H; Carlson O; Chines PS; Clarke R; Collins FS; Corbaton-Anchuelo A; Couper D; de Faire U; Dedoussis GV; Deloukas P; Dimitriou M; Egan JM; Eiriksdottir G; Erdos MR; Eriksson JG; Eury E; Ferrucci L; Ford I; Forouhi NG; Fox CS; Franzosi MG; Franks PW; Frayling TM; Froguel P; Galan P; de Geus E; Gigante B; Glazer NL; Goel A; Groop L; Gudnason V; Hallmans G; Hamsten A; Hansson O; Harris TB; Hayward C; Heath S; Hercberg S; Hicks AA; Hingorani A; Hofman A; Hui J; Hung J; Jarvelin M-R; Jhun MA; Johnson PCD; Jukema JW; Jula A; Kao WH; Kaprio J; Kardia SLR; Keinanen-Kiukaanniemi S; Kivimaki M; Kolcic I; Kovacs P; Kumari M; Kuusisto J; Kyvik KO; Laakso M; Lakka T; Lannfelt L; Lathrop GM; Launer LJ; Leander K; Li G; Lind L; Lindstrom J; Lobbens S; Loos RJF; Luan J; Lyssenko V; Magi R; Magnusson PKE; Marmot M; Meneton P; Mohlke KL; Mooser V; Morken MA; Miljkovic I; Narisu N; O'Connell J; Ong KK; Oostra BA; Palmer LJ; Palotie A; Pankow JS; Peden JF; Pedersen NL; Pehlic M; Peltonen L; Penninx B; Pericic M; Perola M; Perusse L; Peyser PA; Polasek O; Pramstaller PP; Province MA; Raikkonen K; Rauramaa R; Rehnberg E; Rice K; Rotter JI; Rudan I; Ruokonen A; Saaristo T; Sabater-Lleal M; Salomaa V; Savage DB; Saxena R; Schwarz P; Seedorf U; Sennblad B; Serrano-Rios M; Shuldiner AR; Sijbrands EJG; Siscovick DS; Smit JH; Small KS; Smith NL; Smith AV; Stancakova A; Stirrups K; Stumvoll M; Sun YV; Swift AJ; Toenjes A; Tuomilehto J; Trompet S; Uitterlinden AG; Uusitupa M; Vikstrom M; Vitart V; Vohl M-C; Voight BF; Vollenweider P; Waeber G; Waterworth DM; Watkins H; Wheeler E; Widen E; Wild SH; Willems SM; Willemsen G; Wilson JF; Witteman JCM; Wright AF; Yaghootkar H; Zelenika D; Zemunik T; Zgaga L; Wareham NJ; McCarthy MI; Barroso I; Watanabe RM; Florez JC; Dupuis J; Meigs JB; Langenberg C
Article: CLINICA CHIMICA ACTA. 2012;413(7-8):727-732
NAMPT (visfatin) and AKT1 genetic variants associate with myocardial infarction
Leander K; Gigante B; Silveira A; Vikstrom M; Hamsten A; Hogberg J
Article: THE LANCET. 2012;379(9822):1205-1213
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
Sarwar N; Butterworth AS; Freitag DF; Gregson J; Willeit P; Gorman DN; Gao P; Saleheen D; Rendon A; Nelson CP; Braund PS; Hall AS; Chasman DI; Tybjaerg-Hansen A; Chambers JC; Benjamin EJ; Franks PW; Clarke R; Wilde AAM; Trip MD; Steri M; Witteman JCM; Qi L; van der Schoot CE; de Faire U; Erdmann J; Stringham HM; Koenig W; Rader DJ; Melzer D; Reich D; Psaty BM; Kleber ME; Panagiotakos DB; Willeit J; Wennberg P; Woodward M; Adamovic S; Rimm EB; Meade TW; Gillum RF; Shaffer JA; Hofman A; Onat A; Sundstrom J; Wassertheil-Smoller S; Mellstrom D; Gallacher J; Cushman M; Tracy RP; Kauhanen J; Karlsson M; Salonen JT; Wilhelmsen L; Amouyel P; Cantin B; Best LG; Ben-Shlomo Y; Manson JE; Davey-Smith G; de Bakker PIW; O'Donnell CJ; Wilson JF; Wilson AG; Assimes TL; Jansson J-O; Ohlsson C; Tivesten A; Ljunggren O; Reilly MP; Hamsten A; Ingelsson E; Cambien F; Hung J; Thomas GN; Boehnke M; Schunkert H; Asselbergs FW; Kastelein JJP; Gudnason V; Salomaa V; Harris TB; Kooner JS; Allin KH; Nordestgaard BG; Hopewell JC; Goodall AH; Ridker PM; Holm H; Watkins H; Ouwehand WH; Samani NJ; Kaptoge S; Di Angelantonio E; Harari O; Danesh J
Article: EUROPEAN HEART JOURNAL. 2012;33(3):393-407
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration
Angelakopoulou A; Shah T; Sofat R; Shah S; Berry DJ; Cooper J; Palmen J; Tzoulaki I; Wong A; Jefferis BJ; Maniatis N; Drenos F; Gigante B; Hardy R; Laxton RC; Leander K; Motterle A; Simpson IA; Smeeth L; Thomson A; Verzilli C; Kuh D; Ireland H; Deanfield J; Caulfield M; Wallace C; Samani N; Munroe PB; Lathrop M; Fowkes FGR; Marmot M; Whincup PH; Whittaker JC; de Faire U; Kivimaki M; Kumari M; Hypponen E; Power C; Humphries SE; Talmud PJ; Price J; Morris RW; Ye S; Casas JP; Hingorani AD
Article: RADIOTHERAPY AND ONCOLOGY. 2011;100(2):167-175
Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden
McGale P; Darby SC; Hall P; Adolfsson J; Bengtsson N-O; Bennet AM; Fornander T; Gigante B; Jensen M-B; Peto R; Rahimi K; Taylor CW; Ewertz M
Article: NATURE GENETICS. 2011;43(4):333-338
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Schunkert H; Koenig IR; Kathiresan S; Reilly MP; Assimes TL; Holm H; Preuss M; Stewart AFR; Barbalic M; Gieger C; Absher D; Aherrahrou Z; Allayee H; Altshuler D; Anand SS; Andersen K; Anderson JL; Ardissino D; Ball SG; Balmforth AJ; Barnes TA; Becker DM; Becker LC; Berger K; Bis JC; Boekholdt SM; Boerwinkle E; Braund PS; Brown MJ; Burnett MS; Buysschaert I; Carlquist JF; Chen L; Cichon S; Codd V; Davies RW; Dedoussis G; Dehghan A; Demissie S; Devaney JM; Diemert P; Do R; Doering A; Eifert S; El Mokhtari NE; Ellis SG; Elosua R; Engert JC; Epstein SE; de Faire U; Fischer M; Folsom AR; Freyer J; Gigante B; Girelli D; Gretarsdottir S; Gudnason V; Gulcher JR; Halperin E; Hammond N; Hazen SL; Hofman A; Horne BD; Illig T; Iribarren C; Jones GT; Jukema JW; Kaiser MA; Kaplan LM; Kastelein JJP; Khaw K-T; Knowles JW; Kolovou G; Kong A; Laaksonen R; Lambrechts D; Leander K; Lettre G; Li M; Lieb W; Loley C; Lotery AJ; Mannucci PM; Maouche S; Martinelli N; McKeown PP; Meisinger C; Meitinger T; Melander O; Merlini PA; Mooser V; Morgan T; Muehleisen TW; Muhlestein JB; Muenzel T; Musunuru K; nahrstaedt J; Nelson CP; Noethen MM; Olivieri O; Patel RS; Patterson CC; Peters A; Peyvandi F; Qu L; Quyyumi AA; Rader DJ; Rallidis LS; Rice C; Rosendaal FR; Rubin D; Salomaa V; Sampietro ML; Sandhu MS; Schadt E; Schaefer A; Schillert A; Schreiber S; Schrezenmeir J; Schwartz SM; Siscovick DS; Sivananthan M; Sivapalaratnam S; Smith A; Smith TB; Snoep JD; Soranzo N; Spertus JA; Stark K; Stirrups K; Stoll M; Tang WHW; Tennstedt S; Thorgeirsson G; Thorleifsson G; Tomaszewski M; Uitterlinden AG; van Rij AM; Voight BF; Wareham NJ; Wells GA; Wichmann H-E; Wild PS; Willenborg C; Witteman JCM; Wright BJ; Ye S; Zeller T; Ziegler A; Cambien F; Goodall AH; Cupples LA; Quertermous T; Maerz W; Hengstenberg C; Blankenberg S; Ouwehand WH; Hall AS; Deloukas P; Thompson JR; Stefansson K; Roberts R; Thorsteinsdottir U; O'Donnell CJ; McPherson R; Erdmann J; Samani NJ
Article: NATURE GENETICS. 2011;43(4):339-U89
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
Peden JF; Hopewell JC; Saleheen D; Chambers JC; Hager J; Soranzo N; Collins R; Danesh J; Elliott P; Farrall M; Stirrups K; Zhang W; Hamsten A; Parish S; Lathrop M; Watkins H; Clarke R; Deloukas P; Kooner JS; Goel A; Ongen H; Strawbridge RJ; Heath S; Malarstig A; Helgadottir A; Ohrvik J; Murtaza M; Potter S; Hunt SE; Delepine M; Jalilzadeh S; Axelsson T; Syvanen A-C; Gwilliam R; Bumpstead S; Gray E; Edkins S; Folkersen L; Kyriakou T; Franco-Cereceda A; Gabrielsen A; Seedorf U; Eriksson P; Offer A; Bowman L; Sleight P; Armitage J; Peto R; Abecasis G; Ahmed N; Caulfield M; Donnelly P; Froguel P; Kooner AS; McCarthy MI; Samani NJ; Scott J; Sehmi J; Silveira A; Hellenius M-L; van't Hooft FM; Olsson G; Rust S; Assmann G; Barlera S; Tognoni G; Franzosi MG; Linksted P; Green FR; Rasheed A; Zaidi M; Shah N; Samuel M; Mallick NH; Azhar M; Zaman KS; Samad A; Ishaq M; Gardezi AR; Memon F-U; Frossard PM; Spector T; Peltonen L; Nieminen MS; Sinisalo J; Salomaa V; Ripatti S; Bennett D; Leander K; Gigante B; de Faire U; Pietri S; Gori F; Marchioli R; Sivapalaratnam S; Kastelein JJP; Trip MD; Theodoraki EV; Dedoussis GV; Engert JC; Yusuf S; Anand SS
Article: THE BMJ. 2011;342:d548
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
Wensley F; Gao P; Burgess S; Kaptoge S; Di Angelantonio E; Shah T; Engert JC; Clarke R; Davey-Smith G; Nordestgaard BG; Saleheen D; Samani NJ; Sandhu M; Anand S; Pepys MB; Smeeth L; Whittaker J; Casas JP; Thompson SG; Hingorani AD; Danesh J; Eiriksdottir G; Harris TB; Launer LJ; Gudnason V; Folsom AR; Andrews G; Ballantyne CM; Samani NJ; Hall AS; Braund PS; Balmforth AJ; Whincup PH; Morris R; Lawlor DA; Lowe GDO; Timpson N; Ebrahim S; Ben-Shlomo Y; Davey-Smith G; Timpson N; Nordestgaard BG; Tybjaerg-Hansen A; Zacho J; Brown M; Sandhu M; Ricketts SL; Ashford S; Lange L; Reiner A; Cushman M; Tracy R; Wu C; Ge J; Zou Y; Sun A; Hung J; McQuillan B; Thompson P; Beilby J; Warrington N; Palmer LJ; Wanner C; Drechsler C; Hoffmann MM; Fowkes FGR; Lowe GDO; Tzoulaki I; Kumari M; Miller M; Marmot M; Onland-Moret C; van der Schouw YT; Boer JM; Wijmenga C; Ricketts SL; Ashford S; Sandhu M; Khaw K-T; Vasan RS; Schnabel RB; Yamamoto JF; Benjamin EJ; Schunkert H; Erdmann J; Koenig IR; Hengstenberg C; Chiodini B; Franzosi MG; Pietri S; Gori F; Rudock M; Liu Y; Lohman K; Harris TB; Humphries SE; Hamsten A; Norman PE; Hankey GJ; Jamrozik K; Palmer LJ; Rimm EB; Pai JK; Psaty BM; Heckbert SR; Bis JC; Yusuf S; Anand S; Engert JC; Xie C; Collins R; Clarke R; Bennett D; Kooner J; Chambers J; Elliott P; Maerz W; Kleber ME; Boehm BO; Winkelmann BR; Melander O; Berglund G; Koenig W; Thorand B; Baumert J; Peters A; Rimm EB; Manson J; Pai JK; Humphries SE; Cooper JA; Talmud PJ; Ladenvall P; Johansson L; Jansson J-H; Hallmans G; Reilly MP; Qu L; Li M; Rader DJ; Watkins H; Clarke R; Hopewell J; Saleheen D; Danesh J; Frossard P; Sattar N; Robertson M; Shepherd J; Schaefer E; Hofman A; Witteman JCM; Kardys I; Dehghan A; de Faire U; Bennet A; Gigante B; Leander K; Ben-Shlomo Y; Davey-Smith G; Timpson N; Peters B; Maitland-van der Zee AH; de Boer A; Klungel O; Reiner A; Manson J; Greenland P; Dai J; Liu S; Kumari M; Brunner E; Kivimaki M; Marmot M; Sattar N; O'Reilly D; Ford I; Packard CJ
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 2010;59(12):1736-1741
Apolipoprotein C-I genotype and serum levels of triglycerides, C-reactive protein and coronary heart disease
Olsson B; Gigante B; Mehlig K; Bergsten A; Leander K; de Faire U; Lissner L; Thelle DS; Carlsson LMS
Article: CIRCULATION. 2010;122(5):470-477
Genetic Variation at the Phospholipid Transfer Protein Locus Affects Its Activity and High-Density Lipoprotein Size and Is a Novel Marker of Cardiovascular Disease Susceptibility
Vergeer M; Boekholdt SM; Sandhu MS; Ricketts SL; Wareham NJ; Brown MJ; de Faire U; Leander K; Gigante B; Kavousi M; Hofman A; Uitterlinden AG; van Duijn CM; Witteman JCM; Jukema JW; Schadt EE; van der Schoot E; Kastelein JJP; Khaw K-T; Dullaart RPF; van Tol A; Trip MD; Dallinga-Thie GM
Article: PLOS ONE. 2010;5(6):e11300
The Interaction between Coagulation Factor 2 Receptor and Interleukin 6 Haplotypes Increases the Risk of Myocardial Infarction in Men
Gigante B; Bennet AM; Leander K; Vikstrom M; de Faire U
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2009;361(26):2518-2528
Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease
Clarke R; Peden JF; Hopewell JC; Kyriakou T; Goel A; Heath SC; Parish S; Barlera S; Franzosi MG; Rust S; Bennett D; Silveira A; Malarstig A; Green FR; Lathrop M; Gigante B; Leander K; de Faire U; Seedorf U; Hamsten A; Collins R; Watkins H; Farrall M
Article: PLOS GENETICS. 2009;5(12):e1000754
Multi-Organ Expression Profiling Uncovers a Gene Module in Coronary Artery Disease Involving Transendothelial Migration of Leukocytes and LIM Domain Binding 2: The Stockholm Atherosclerosis Gene Expression (STAGE) Study
Hagg S; Skogsberg J; Lundstrom J; Noori P; Nilsson R; Zhong H; Maleki S; Shang M-M; Brinne B; Bradshaw M; Bajic VB; Samnegard A; Silveira A; Kaplan LM; Gigante B; Leander K; de Faire U; Rosfors S; Lockowandt U; Liska J; Konrad P; Takolander R; Franco-Cereceda A; Schadt EE; Ivert T; Hamsten A; Tegner J; Bjorkegren J
Article: CORONARY ARTERY DISEASE. 2009;20(5):322-326
The myeloperoxidase gene and its influence on myocardial infarction in a Swedish population: protective role of the-129A allele in women
Zotova E; Lyrenas L; de Faire U; Morgenstern R; Gigante B; Bennet AM
Article: THROMBOSIS AND HAEMOSTASIS. 2009;101(5):943-953
Variants in the coagulation factor 2 receptor (F2R) gene influence the risk of myocardial infarction in men through an interaction with interleukin 6 serum levels
Gigante B; Vikstrom M; Meuzelaar LS; Chernogubova E; Silveira A; van't Hooft F; Hamsten A; de Faire U
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2007;27(5):1213-1219
Retrospective analysis of coagulation factor II receptor (F2R) sequence variation and coronary heart disease in hypertensive patients
Gigante B; Bellis A; Visconti R; Marino M; Morisco C; Trimarco V; Galasso G; Piscione F; De Luca N; Prince JA; de Faire U; Trimarco B
Article: THE FASEB JOURNAL. 2006;20(7):970-972
Plgf^-/- eNos^-/- mice show defective angiogenesis associated with increased oxidative stress in response to tissue ischemia
Gigante B; Morlino G; Gentile MT; Persico MG; De Falco S
Article: THROMBOSIS AND HAEMOSTASIS. 2005;93(6):1095-1100
Polymorphisms in prothrombotic genes and their impact on ischemic stroke in a Sardinian population
Rubattu S; Di Angelantonio E; Nitsch D; Gigante B; Zanda B; Stanzione R; Evangelista A; Pirisi A; Rosati G; Volpe M
Article: STROKE. 2004;35(4):814-818
Atrial natriuretic peptide gene Polymorphisms and risk of ischemic stroke in humans
Rubattu S; Stanzione R; Di Angelantonio E; Zanda B; Evangelista A; Tarasi D; Gigante B; Pirisi A; Brunetti E; Volpe M
Article: ANGIOGENESIS. 2004;7(3):277-284
Placenta growth factor is not required for exercise-induced angiogenesis.
Gigante B; Tarsitano M; Cimini V; De Falco S; Persico MG
Article: JOURNAL OF HYPERTENSION. 2002;20(4):693-699
Functional cross-talk between angiotensin II and epidermal growth factor receptors in NIH3T3 fibroblasts
De Paolis P; Porcellini A; Savoia C; Lombardi A; Gigante B; Frati G; Rubattu S; Musumeci B; Volpe M
Article: EUROPEAN HEART JOURNAL. 2001;22(15):1328-1336
Determinants and clinical significance of natriuretic peptides in hypertrophic cardiomyopathy
Briguori C; Betocchi S; Manganelli F; Gigante B; Losi MA; Ciampi Q; Gottilla R; Violante A; Tocchetti CG; Volpe M; Chiariello M
Article: CYTOGENETIC AND GENOME RESEARCH. 2001;95(1-2):64-72
Non-random chromosomal distribution of SSLPs: systematic assessment using a novel genetic linkage map between two closely related rat strains
Gigante B; Rubattu S; Zee RYL; Volpe M; Lindpaintner K
Article: BASIC RESEARCH IN CARDIOLOGY. 2000;95(2):84-92
Defective suppression of the aldosterone biosynthesis during stroke permissive diet in the stroke-prone phenotype of the spontaneously hypertensive rat
Enea I; De Paolis P; Porcellini A; Piras O; Savoia C; Russo R; Giliberti R; Gigante B; Rubattu S; Conte G; Ganten D; Volpe M
Article: JOURNAL OF HYPERTENSION. 2000;18(2):161-165
Analysis of the genetic basis of the endothelium-dependent impaired vasorelaxation in the stroke-prone spontaneously hypertensive rat: a candidate gene approach
Rubattu S; Giliberti R; Russo R; Gigante B; Ganten U; Volpe M
Article: BASIC RESEARCH IN CARDIOLOGY. 2000;95(1):64-69
Role of angiotensin II AT₁ and AT₂ subtype receptors in the regulation of atrial natriuretic peptide expression in salt-restricted rats
Gigante B; Piras O; Savoia C; De Paolis P; Rubattu S; Panina G; Volpe M
Article: CIRCULATION RESEARCH. 1999;85(10):900-905
Altered structure, regulation, and function of the gene encoding the atrial natriuretic peptide in the stroke-prone spontaneously hypertensive rat
Rubattu S; Lee-Kirsch MA; DePaolis P; Giliberti R; Gigante B; Lombardi A; Volpe M; Lindpaintner K
Article: CIRCULATION RESEARCH. 1997;81(5):857-864
Role of tissue renin in the regulation of aldosterone biosynthesis in the adrenal cortex of nephrectomized rats
Volpe M; Gigante B; Enea I; Porcellini A; Russo R; Lee MA; Magri P; Condorelli G; Savoia C; Lindpaintner K; Rubattu S
Article: HYPERTENSION. 1997;30(2):168-176
Intrarenal determinants of sodium retention in mild heart failure - Effects of angiotensin-converting enzyme inhibition
Volpe M; Magri P; Rao MAE; Cangianiello S; DeNicola L; Mele AF; Memoli B; Enea I; Rubattu S; Gigante B; Trimarco B; Epstein M; Condorelli M
Article: JOURNAL OF HYPERTENSION. 1995;13(11):1253-1258
Regulation of 11 beta-hydroxylase cytochrome P450 expression by cholesterol in spontaneously hypertensive rats
Rubattu S; Russo R; Gigante B; Porcellini A; Finizia L; Trimarco B; Volpe M
Article: CIRCULATION RESEARCH. 1995;77(1):73-79
REGULATION OF ALDOSTERONE BIOSYNTHESIS BY ADRENAL RENIN IS MEDIATED THROUGH AT(1) RECEPTORS IN RENIN TRANSGENIC RATS
VOLPE M; RUBATTU S; GIGANTE B; GANTEN D; PORCELLINI A; RUSSO R; ROMANO M; ENEA I; LEE MA; TRIMARCO B
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Editorial comment: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2024;31(17):2056-2057
Do low levels of albuminuria predict mortality among young adults without major cardiovascular risk factors?
Velasquez IM; Gigante B
Review: EUROPEAN HEART JOURNAL (EHJ) - CARDIOVASCULAR PHARMACOTHERAPY. 2024;10(7):614-645
Update on antithrombotic therapy and body mass: a clinical consensus statement of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy and the European Society of Cardiology Working Group on Thrombosis
Gigante B; Tamargo J; Agewall S; Atar D; ten Berg J; Campo G; Cerbai E; Christersson C; Dobrev D; Ferdinandy P; Geisler T; Gorog DA; Grove EL; Kaski JC; Rubboli A; Wassmann S; Wallen H; Rocca B
Review: CARDIOLOGY. 2024;149(5):513-522
Infective endocarditis and antithrombotic therapy
Morelli C; Rocca B; Gigante B
Editorial comment: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2023;30(18):2015-2017
Cancer and cardiovascular diseases: the long, winding and crossing roads
Gigante B; Langley RE; Rocca B
Editorial comment: NATURE REVIEWS CARDIOLOGY. 2023;20(8):511-512
Factor XI inhibitors in patients with cardiovascular disease and a high risk of bleeding: a cautionary tale
Gigante B; Cate HT
Preprint: RESEARCH SQUARE. 2023
Causes of death after first time venous thromboembolism
Lonnberg F; Roos A; Farm M; Heurlin A; Okas M; Gigante B; Siddiqui AJ
Editorial comment: EUROPEAN HEART JOURNAL. 2023;44(19):1715-1717
To be or not to be admitted to the emergency department for chest pain? A costly dilemma
Gigante B
Preprint: MEDRXIV. 2023
Identification of a specific inflammatory protein biosignature in coronary and peripheral blood associated with increased risk of future cardiovascular events
Proudfoot D; Gigante B; West NEJ; Hoole S; Strawbridge R; Tremoli E; Baldassarre D; Williams S
Review: EUROPEAN HEART JOURNAL. 2023;44(4):262-279
Acute, periprocedural and longterm antithrombotic therapy in older adults 2022 Update by the ESC Working Group on Thrombosis
Andreotti F; Geisler T; Collet J-P; Gigante B; Gorog DA; Halvorsen S; Lip GYH; Morais J; Navarese EP; Patrono C; Rocca B; Rubboli A; Sibbing D; Storey RF; Verheugt FWA; Vilahur G
Editorial comment: EUROPEAN CARDIOLOGY REVIEW. 2023;18:e13
Present and Future Perspectives on the Role of Biomarkers in Atherosclerotic Cardiovascular Disease Risk Stratification
Gigante B
Corrigendum: BMC NEUROLOGY. 2022;22(1):337
IL6 trans-signaling associates with ischemic stroke but not with atrial fibrillation (vol 21, 306, 2021)
Ziegler L; Wallen H; Aspberg S; de Faire U; Gigante B
Conference publication: ATHEROSCLEROSIS. 2022;355:E158
SMALL LDL SUBFRACTIONS ARE ASSOCIATED WITH CORONARY ATHEROSCLEROSIS
Saether JC; Bye A; Klevjer M; Bathen TF; Giskeodegard G; Madssen E; Vesterbekkmo E; Wiseth R; Gjaere S; Myhra M; Gigante B
Review: PLOS MEDICINE. 2021;18(9):e1003763
Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis
Trieu K; Bhat S; Dai Z; Leander K; Gigante B; Qian F; Korat AVA; Sun Q; Pan X-F; Laguzzi F; Cederholm T; de Faire U; Hellenius M-L; Wu JHY; Riserus U; Marklund M
Preprint: MEDRXIV. 2021
Mapping genetic determinants of 184 circulating proteins in 26,494 individuals to connect proteins and diseases
Macdonald-Dunlop E; Klarić L; Folkersen L; Timmers PRHJ; Gustafsson S; Zhao JH; Eriksson N; Richmond A; Enroth S; Mattsson-Carlgren N; Zhernakova DV; Kalnapenkis A; Magnusson M; Wheeler E; Hwang S-J; Chen Y; Morris AP; Prins B; Võsa U; Wareham NJ; Danesh J; Sundstrom J; Gigante B; Baldassarre D; Strawbridge RJ; Campbell H; Gyllensten U; Yao C; Zanetti D; Assimes TL; Eriksson P; Levy D; Langenberg C; Smith JG; Esko T; Fu J; Hansson O; Johansson Å; Hayward C; Wallentin L; Siegbahn A; Lind L; Butterworth AS; Michaëlsson K; Peters JE; Mälarstig A; Joshi PK; Wilson JF
Conference publication: CIRCULATION. 2021;143:a026
Biomarkers Of Dairy Fat Intake Associated With Lower Cardiovascular Disease Risk: A Cohort Study And Meta-analysis
Trieu K; Bhat S; Dai Z; Leander K; Gigante B; Qian F; Korat AA; Sun Q; Pan X; Laguzzi F; Cederholm T; De Faire U; Hellenius M-L; Wu JH; Riserus U; Marklund M
Review: EUROPEAN HEART JOURNAL: ACUTE CARDIOVASCULAR CARE. 2021;10(3):343-355
Biomarkers of coagulation and fibrinolysis in acute myocardial infarction: a joint position paper of the Association for Acute Cardio Vascular Care and the European Society of Cardiology Working Group on Thrombosis
Krychtiuk KA; Speidl WS; Giannitsis E; Gigante B; Gorog DA; Jaffe AS; Mair J; Moeckel M; Mueller C; Storey RF; Vilahur G; Wojta J; Huber K; Halvorsen S; Geisler T; Morais J; Lindahl B; Thygesen K
Preprint: MEDRXIV. 2021;MEDRXIV
Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19.
Klaric L; Gisby JS; Papadaki A; Muckian MD; Macdonald-Dunlop E; Zhao JH; Tokolyi A; Persyn E; Pairo-Castineira E; Morris AP; Kalnapenkis A; Richmond A; Landini A; Hedman ÅK; Prins B; Zanetti D; Wheeler E; Kooperberg C; Yao C; Petrie JR; Fu J; Folkersen L; Walker M; Magnusson M; Eriksson N; Mattsson-Carlgren N; Timmers PRHJ; Hwang S-J; Enroth S; Gustafsson S; Vosa U; Chen Y; Siegbahn A; Reiner A; Johansson Å; Thorand B; Gigante B; Hayward C; Herder C; Gieger C; Langenberg C; Levy D; Zhernakova DV; Smith JG; Campbell H; Sundstrom J; Danesh J; Michaëlsson K; Suhre K; Lind L; Wallentin L; Padyukov L; Landén M; Wareham NJ; Göteson A; Hansson O; Eriksson P; Strawbridge RJ; Assimes TL; Esko T; Gyllensten U; Baillie JK; Paul DS; Joshi PK; Butterworth AS; Mälarstig A; Pirastu N; Wilson JF; Peters JE
Conference publication: EUROPEAN HEART JOURNAL. 2021;42:2510
IL6 trans-signalling is associated with a higher risk of cardiovascular events in individuals with diabetes
Ziegler L; Gigante B
Conference publication: EUROPEAN HEART JOURNAL. 2020;41:1353
Lipoprotein subfraction LDL-5 and the presence of coronary atherosclerosis
Klevjer M; Saether JC; Vesterbekkmo E; Giskeoedegaard G; Bathen T; Gigante B; Gjaere S; Myhra M; Wiseth R; Madssen E; Bye A
Letter: CELL DEATH AND DISEASE. 2020;11(1):74
MicroRNA signatures predict early major coronary events in middle-aged men and women
Gigante B; Papa L; Bye A; Kunderfranco P; Viviani C; Roncarati R; Briguori C; de Faire U; Bottai M; Condorelli G
Conference publication: EUROPEAN HEART JOURNAL. 2019;40:824
IL6 trans-signalling affects risk of cardiovascular events pre-eminently in men
Ziegler L; Frumento P; Wallen H; De Faire U; Gigante B
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1242
GENETIC ANALYSIS OF CADM2, A POSSIBLE LINK BETWEEN MENTAL AND PHYSICAL HEALTH
Morris J; Bailey M; Baldassarre D; Cullen B; defaire U; Gigante B; Graham N; Hamsten A; Humphries S; Lyall D; Sennblad B; Smit A; Watkins H; Smith D; Strawbridge R
Conference publication: JOURNAL OF HYPERTENSION. 2018;36:E187
THE EFFECTS OF ANGIOTENSIN CONVERTING ENZYME INHIBITION AND ALPHA 1-ADRENERGIC RECEPTOR BLOCKADE ON HAEMOSTASIS AND INFLAMMATION IN MILD-TO-MODERATE HYPERTENSION
Ekholm M; Jekell A; Wallen NH; Gigante B; Kahan T
Conference publication: THROMBOSIS RESEARCH. 2018;164:S209
Cancer diagnosis as a risk factor of ischemic stroke in atrial fibrillation patients with low stroke risk score
Atterman A; Gigante B; Asplund K; Aspberg S
Conference publication: EUROPEAN HEART JOURNAL. 2018;39:524-525
The soluble IL6 receptor and ischemic cerebrovascular disease
Ziegler L; Lundqvist J; Perisic L; Gajulapuri A; Dreij K; Frumento P; Paulsson-Berne G; Wallen H; De Faire U; Hedin U; Gigante B
Conference publication: EUROPEAN HEART JOURNAL. 2018;39:1329
Pulmonary embolism is a possible risk factor for ischemic stroke before 65 years of age in patients with atrial fibrillation
Aspberg S; Smedback K; Gigante B; Yu L; Chang Y; Singer DE
Conference publication: ANNALS OF NUTRITION AND METABOLISM. 2017;71:322-323
SERUM PENTADECANOIC ACID, A BIOMARKER OF DAIRY FAT INTAKE, IS ASSOCIATED WITH LOWER RISK OF INCIDENT CARDIOVASCULAR DISEASE AND ALL-CAUSE MORTALITY IN SWEDISH MEN AND WOMEN
Marklund M; Leander K; Vikstrom M; Laguzzi F; Gigante B; Sjogren P; Cederholm T; de Faire U; Hellenius M-L; Riserus U
Conference publication: CIRCULATION. 2017;136
Novel Genetic Variants Associated With Circulating Soluble Glycoprotein 130 Levels in The IMPROVE Study
Bonomi A; Veglia F; Baldassarre D; Golabkesh Z; Strawbridge R; Hamsten A; Tremoli E; de Faire U; Gigante B
Corrigendum: PLOS GENETICS. 2016;12(6):e1006166
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (vol 11, e1005378, 2015)
Winkler TW; Justice AE; Graff M; Barata L; Feitosa MF; Chu S; Czajkowski J; Esko T; Fall T; Kilpelainen TO; Lu Y; Magi R; Mihailov E; Pers TH; Rueger S; Teumer A; Ehret GB; Ferreira T; Heard-Costa NL; Karjalainen J; Lagou V; Mahajan A; Neinast MD; Prokopenko I; Simino J; Teslovich TM; Jansen R; Westra H-J; White CC; Absher D; Ahluwalia TS; Ahmad S; Albrecht E; Alves AC; Bragg-Gresham JL; de Craen AJM; Bis JC; Bonnefond A; Boucher G; Cadby G; Cheng Y-C; Chiang CWK; Delgado G; Demirkan A; Dueker N; Eklund N; Eiriksdottir G; Eriksson J; Feenstra B; Fischer K; Frau F; Galesloot TE; Geller F; Goel A; Gorski M; Grammer TB; Gustafsson S; Haitjema S; Hottenga J-J; Huffman JE; Jackson AU; Jacobs KB; Johansson A; Kaakinen M; Kleber ME; Lahti J; Leach IM; Lehne B; Liu Y; Lo KS; Lorentzon M; Luan J; Madden PAF; Mangino M; McKnight B; Medina-Gomez C; Monda KL; Montasser ME; Muller G; Muller-Nurasyid M; Nolte IM; Panoutsopoulou K; Pascoe L; Paternoster L; Rayner NW; Renstrom F; Rizzi F; Rose LM; Ryan KA; Salo P; Sanna S; Scharnagl H; Shi J; Smith AV; Southam L; Stancakova A; Steinthorsdottir V; Strawbridge RJ; Sung YJ; Tachmazidou I; Tanaka T; Thorleifsson G; Trompet S; Pervjakova N; Tyrer JP; Vandenput L; van der Laan SW; van der Velde N; van Setten J; van Vliet-Ostaptchouk JV; Verweij N; Vlachopoulou E; Waite LL; Wang SR; Wang Z; Wild SH; Willenborg C; Wilson JF; Wong A; Yang J; Yengo L; Yerges-Armstrong LM; Yu L; Zhang W; Zhao JH; Andersson EA; Bakker SJL; Baldassarre D; Banasik K; Barcella M; Barlassina C; Bellis C; Benaglio P; Blangero J; Bluher M; Bonnet F; Bonnycastle LL; Boyd HA; Bruinenberg M; Buchman AS; Campbell H; Chen Y-DI; Chines PS; Claudi-Boehm S; Cole J; Collins FS; de Geus EJC; de Groot LCPGM; Dimitriou M; Duan J; Enroth S; Eury E; Farmaki A-E; Forouhi NG; Friedrich N; Gejman PV; Gigante B; Glorioso N; Go AS; Gottesman O; Grassler J; Grallert H; Grarup N; Gu Y-M; Broer L; Ham AC; Hansen T; Harris TB; Hartman CA; Hassinen M; Hastie N; Hattersley AT; Heath AC; Henders AK; Hernandez D; Hillege H; Holmen O; Hovingh KG; Hui J; Husemoen LL; Hutri-Kahonen N; Hysi PG; Illig T; De Jager PL; Jalilzadeh S; Jorgensen T; Jukema JW; Juonala M; Kanoni S; Karaleftheri M; Khaw KT; Kinnunen L; Kittner SJ; Koenig W; Kolcic I; Kovacs P; Krarup NT; Kratzer W; Kruger J; Kuh D; Kumari M; Kyriakou T; Langenberg C; Lannfelt L; Lanzani C; Lotay V; Launer LJ; Leander K; Lindstrom J; Linneberg A; Liu Y-P; Lobbens S; Luben R; Lyssenko V; Mannisto S; Magnusson PK; McArdle WL; Menni C; Merger S; Milani L; Montgomery GW; Morris AP; Narisu N; Nelis M; Ong KK; Palotie A; Perusse L; Pichler I; Pilia MG; Pouta A; Rheinberger M; Ribel-Madsen R; Richards M; Rice KM; Rice TK; Rivolta C; Salomaa V; Sanders AR; Sarzynski MA; Scholtens S; Scott RA; Scott WR; Sebert S; Sengupta S; Sennblad B; Seufferlein T; Silveira A; Slagboom PE; Smit JH; Sparso TH; Stirrups K; Stolk RP; Stringham HM; Swertz MA; Swift AJ; Syvanen A-C; Tan S-T; Thorand B; Tonjes A; Tremblay A; Tsafantakis E; van der Most PJ; Volker U; Vohl M-C; Vonk JM; Waldenberger M; Walker RW; Wennauer R; Widen E; Willemsen G; Wilsgaard T; Wright AF; Zillikens MC; van Dijk SC; van Schoor NM; Asselbergs FW; de Bakker PIW; Beckmann JS; Beilby J; Bennett DA; Bergman RN; Bergmann S; Boger CA; Boehm BO; Boerwinkle E; Boomsma DI; Bornstein SR; Bottinger EP; Bouchard C; Chambers JC; Chanock SJ; Chasman DI; Cucca F; Cusi D; Dedoussis G; Erdmann J; Eriksson JG; Evans DA; de Faire U; Farrall M; Ferrucci L; Ford I; Franke L; Franks PW; Froguel P; Gansevoort RT; Gieger C; Gronberg H; Gudnason V; Gyllensten U; Hall P; Hamsten A; van der Harst P; Hayward C; Heliovaara M; Hengstenberg C; Hicks AA; Hingorani A; Hofman A; Hu F; Huikuri HV; Hveem K; James AL; Jordan JM; Jula A; Kahonen M; Kajantie E; Kathiresan S; Kiemeney LALM; Kivimaki M; Knekt PB; Koistinen HA; Kooner JS; Koskinen S; Kuusisto J; Maerz W; Martin NG; Laakso M; Lakka TA; Lehtimaki T; Lettre G; Levinson DF; Lind L; Lokki M-L; Mantyselka P; Melbye M; Metspalu A; Mitchell BD; Moll FL; Murray JC; Musk AW; Nieminen MS; Njolstad I; Ohlsson C; Oldehinkel AJ; Oostra BA; Palmer LJ; Pankow JS; Pasterkamp G; Pedersen NL; Pedersen O; Penninx BW; Perola M; Peters A; Polasek O; Pramstaller PP; Psaty BM; Qi L; Quertermous T; Raitakari OT; Rankinen T; Rauramaa R; Ridker PM; Rioux JD; Rivadeneira F; Rotter JI; Rudan I; den Ruijter HM; Saltevo J; Sattar N; Schunkert H; Schwarz PEH; Shuldiner AR; Sinisalo J; Snieder H; Sorensen TIA; Spector TD; Staessen JA; Stefania B; Thorsteinsdottir U; Stumvoll M; Tardif J-C; Tremoli E; Tuomilehto J; Uitterlinden AG; Uusitupa M; Verbeek ALM; Vermeulen SH; Viikari JS; Vitart V; Volzke H; Vollenweider P; Waeber G; Walker M; Wallaschofski H; Wareham NJ; Watkins H; Zeggini E; Chakravarti A; Clegg DJ; Cupples LA; Gordon-Larsen P; Jaquish CE; Rao DC; Abecasis GR; Assimes TL; Barroso I; Berndt SI; Boehnke M; Deloukas P; Fox CS; Groop LC; Hunter DJ; Ingelsson E; Kaplan RC; McCarthy MI; Mohlke KL; O'Connell JR; Schlessinger D; Strachan DP; Stefansson K; van Duijn CM; Hirschhorn JN; Lindgren CM; Heid IM; North KE; Borecki IB; Kutalik Z; Loos RJF
Letter: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2014;173(3):560
Response to: Modifiable lifestyle risks, cardiovascular disease, and all-cause mortality
Carlsson AC; Wandell PE; Gigante B; Leander K; Hellenius M-L; de Faire U
Meeting abstract: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2010;78(3):S49-S50
A Dose-response Relationship for the Incidence of Radiation-related Heart Disease
Darby SC; Bronnum D; Correa C; Ewertz M; Gagliardi G; Gigante B; McGale P; Nisbet A; Taylor C; Hall P
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2010;11(2):13
COMMON GENETIC VARIANTS ASSOCIATED WITH LOW Lp(a) KRINGLE-IV COPY NUMBER, HIGH Lp(a) CONCENTRATION, AND INCREASED RISK OF CORONARY HEART DISEASE
Seedorf U; Peden J; Hopewell J; Kyriakou T; Goel A; Heath S; Parish S; Barlera S; Grazia M; Rust S; Bennett D; Silveira A; Malarstig A; Green F; Lathrop M; Gigante B; Leander K; de Faire U; Clarke R; Hamsten A; Collins R; Watkins H
Meeting abstract: ATHEROSCLEROSIS. 2009;207(1):E4
ASSOCIATION STUDY OF CORONARY ARTERY DISEASE (CAD) USING HUMANCVD 50K CHIP
Goel A; Clarke R; Hopewell JC; Kyriakou T; Heath SC; Parish S; Barlera S; Franzosi MG; Rust S; Bennett D; Silveira A; Malarstig A; Green FR; Lathrop M; Gigante B; Leander K; Faire U; Seedorf U; Hamsten A; Collins R; Watkins H; Farrall M; Peden JF
Published conference paper: CELLULAR AND MOLECULAR NEUROBIOLOGY. 2004;24(5):581-588
Role of genetic factors in the etiopathogenesis of cerebrovascular accidents: From an animal model to the human disease
Rubattu S; Stanzione R; Gigante B; Volpe M
Review: AMERICAN JOURNAL OF HYPERTENSION. 2004;17(2):197-202
In the search for stroke genes: a long and winding road
Rubattu S; Gigante B; Stanzione R; De Paolis P; Tarasi D; Volpe M
Published conference paper: HYPERTENSION. 2003;42(4):702-706
Contribution of genetic factors to renal lesions in the stroke-prone spontaneously hypertensive rat
Gigante B; Rubattu S; Stanzione R; Lombardi A; Baldi A; Baldi F; Volpe M
Review: TRENDS IN CARDIOVASCULAR MEDICINE. 2002;12(6):241-246
Structure and function of placental growth factor
De Falco S; Gigante B; Persico MG
Published conference paper: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2001;38:S71-S74
Genetic susceptibility to cerebrovascular accidents
Rubattu T; Stanzione R; Gigante B; Bagalino A; Musumeci B; Volpe M
Published conference paper: JOURNAL OF HYPERTENSION. 1999;17(12):1873-1877
Modulation of the AT₂ subtype receptor gene activation and expression by the AT₁ receptor in endothelial cells
De Paolis P; Porcellini A; Gigante B; Giliberti R; Lombardi A; Savoia C; Rubattu S; Volpe M
Published conference paper: JOURNAL OF HYPERTENSION. 1998;16(12):2039-2043
Role of the angiotensin II AT₂-subtype receptors in the blood pressure-lowering effect of losartan in salt-restricted rats
Gigante B; Piras O; De Paolis P; Porcellini A; Natale A; Volpe M
Published conference paper: HYPERTENSION. 1997;30(3):563-568
Opposite feedback control of renin and aldosterone biosynthesis in the adrenal cortex by angiotensin II AT(1)-subtype receptors
Gigante B; Rubattu S; Russo R; Porcellini A; Enea I; DePaolis P; Savoia C; Natale A; Piras O; Volpe M
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Grants

Endotypes: a customized approach to prevent atherosclerotic cardiovascular disease
Swedish Research Council
1 January 2024 - 31 December 2026
Endotypes: a novel approach to atherothrombotic cardiovascular disease phenotyping
Swedish Heart Lung FOundation
1 January 2024 - 31 December 2026
Can a first-year postpartum intervention program mitigate cardiovascular risk profile, and complications in a future pregnancy in women with preeclampsia in first pregnancy?
Swedish Research Council
1 January 2023 - 31 December 2023
Endotypes: a novel approach to atherosclerotic cardiovascular disease phenotyping
Hjärt-Lungfonden
1 January 2022 - 31 December 2023
The effect of obesity on cardiovascular disease: mediation analysis with Mendelian randomization
Swedish Research Council
1 January 2021 - 31 December 2024
Building capacity for sustainable health – Piloting multisectoral work around sexual and reproductive health, child health and non-communicable diseases in Uganda
Swedish Research Council
1 December 2020 - 31 December 2022
Can lipoprotein subfractions replace traditional lipids in risk prediction of cardiovascular disease?
Central Norway Regional Health Authority
1 January 2020 - 31 December 2023
Do individuals with a family history of cardiovascular disease specifically need to avoid having a diet too low in polyunsaturated fats?
Swedish Research Council
1 January 2020 - 31 December 2022
Improving risk prediction of myocardial infarction by including new types of circulating biomarkers
Central Norway Regional Health Authority
1 January 2019 - 31 December 2022
Cardiometabolic risk factors for fatal and non-fatal cardiovascular events in women and men
Swedish Heart-Lung Foundation
1 January 2019 - 31 December 2021
LADA-LATENT AUTOIMMUNE DIABETES IN ADULTS, RISK FACTORS AND PROGNOSIS
Swedish Research Council
1 January 2019 - 31 December 2022
SNUS, ALCOHOL AND THE RISK OF MICRO- AND MACROVASCULAR DISEASE IN DIABETES
Swedish Research Council for Health Working Life and Welfare
1 October 2017 - 30 September 2020
Stroke prevention in elderly patients with atrial fibrillation: a challenge for the doctors
Swedish Research Council for Health Working Life and Welfare
1 January 2017 - 31 December 2019
Gene-lifestyle interactions behind subclinical cardiovascular disease - explorative analyses based on genome-wide data
Swedish Research Council
1 January 2017 - 31 December 2018
New biomarkers for early risk assessment of CVD (forskerstilling)
Central Norway Regional Health Authority
1 January 2015 - 31 December 2018
Familial factors and cardiovascular disease-genetic-epidemiological studies and molecular mechanisms
Swedish Research Council
1 January 2014 - 31 December 2016
Familial factors and cardiovascular disease - genetic-epidemiological studies and molecular mechanisms.
Swedish Research Council
1 January 2011 - 31 December 2013
Identification of Genes Involved in the Pathogenesis of Stroke in Humans
Council for International Exchange of Scholars
1 September 1997 - 31 August 1998

Employments

Senior Lecturer/Senior Physician, Department of Medicine, Karolinska Institutet, 2022-

Degrees and Education

Docent, Karolinska Institutet, 2011

Supervisor

Ehrlinder Hanne, Förmaksflimmer: Risker och vinster med antikoagulation hos äldre

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