Anna Johansson
About me
I am Docent, Assistant Professor and group leader, as well as a biostatistician and cancer epidemiologist. I lead research in cancer epidemiology, reproductive factors, socioeconomic inequalities, applied statistics and register-based research. My research also spans over the Nordic countries.
I am Visiting Researcher at the Cancer Registry of Norway leading projects on breast cancer using population-based cancer data. I am also project manager and co-leader of two large Nordic research projects: i) Nordic cancer and COVID-19 project and ii) the NORDCAN Survival Studies.
I have collaborations with clinical researchers at Karolinska University Hospital, Capio St Göran Hospital and Uppsala University Hospital.FUNDING: Swedish Cancer Society (Cancerfonden), Swedish Research Council (Vetenskapsrådet), Radiumhemmet Research Foundations, Swedish Breast Cancer Association, Karolinska Institutet Foundations, and the Nordic Cancer Union.
Research
RESEARCH ON CANCER AND PREGNANCY.
My first research interest is cancer in relation to pregnancy and reproductive history, with a special focus on pregnancy-associated cancer, i.e. cancer diagnosed during or within one or two years after a pregnancy. The research questions I am addressing concern the increasing incidence trend, risk patterns before and after delivery, tumour characteristics and survival. I also study other reproductive factors, such as age at births, number of children, infertility and IVF treatment, in relation to cancer risk and prognosis, as well as reproductive outcomes after cancer.
RESEARCH ON BREAST CANCER.
My second research interest is breast cancer among women. I am specifically studying how survival has improved over time, and how it depends on patient, tumour and treatment factors. A key goal is to increase the understanding of socioeconomic inequalities in breast cancer, for example which patient groups have lower access to screening and treatment. I am interested in identifying subgroups of patients at particular high risk for recurrence, treatment complications and lower survival, in particular after accounting for differences in age, comorbidity and socioeconomic position.
NORDIC RESEARCH.
Nordic cancer registries are a goldmine to cancer epidemiology with nationwide coverage of a population of more than 27 million. In collaboration with cancer researchers from Denmark, the Faroe Islands, Finland, Iceland, Norway and Sweden, I am leading and co-leading three large Nordic cancer research efforts on i) pregnancy and cancer, ii) cancer and COVID-19 and iii) cancer survival across the Nordic countries.
METHODS FOR REGISTER-BASED EPIDEMIOLOGY.
As an applied statistician and epidemiologist, I am particularly interested in finding the best way to utilize register data to estimate disease risks in the population, for example by clever study designs and statistical methods for register-based research. Novel methods I use include new ways of estimate and measure cancer survival, and methods to account for missing data in registry data. In my research I utilize the large Swedish population-based cancer registers, such as the National Quality Register for Breast Cancer (NKBC). These unique data sources can be used to answer detailed clinical and epidemiological questions in way that is impossible in many other countries.
RESEARCH DOCUMENTATION AND DATA MANAGEMENT.
The quality of research is highly dependent on the quality of the underlying data. I have worked effortlessly for many years to improve the procedures for research documentation and data management within research projects at KI. This includes everything from standardized variable lists and codes, commented and structure statistical programming, version control to documentation of research projects and ethical approvals.
I have been leading the development of research documentation guidelines in our department, as well as teaching hands-on techniques for research documentation to epidemiologists, clinicians and researchers at KI and elsewhere. I am regularly an invited speaker on this topic. A video of my lecture 2018-11-22 at the KI Library Workshop is available https://play.ki.se/media/0_h64ki6v7 .
Teaching
I have been involved in teaching and course organising of:
• Survival analysis (Biostatistics III), within the Doctoral Programme in Epidemiology
• Epidemiology II, within the Doctoral Programme in Epidemiology
• Competing risks and multistate models
• Epidemiological designs in a statistical framework
• Workshops on epidemiological designs and cancer survival analysis
• Good Data Management Practice in Epidemiology
• Guidelines for Data Management in Clinical Research
Articles
- Article: FERTILITY AND STERILITY. 2024;122(1):95-105
- Article: LUNG CANCER. 2024;192:107826
- Article: ACTA ONCOLOGICA. 2024;63:35232-312
- Article: EUROPEAN JOURNAL OF CANCER. 2024;202:113980
- Article: LEUKEMIA. 2024;38(5):1081-1085
- Article: THE LANCET REGIONAL HEALTH. EUROPE. 2024;40:100886
- Journal article: THE LANCET REGIONAL HEALTH. EUROPE. 2024;40:100886
- Article: ACTA ONCOLOGICA. 2024;63:179-191
- Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2024;103(4):669-683
- Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2024;103(4):684-694
- Article: ESMO OPEN. 2024;9(4):102972
- Article: ACTA ONCOLOGICA. 2024;63:95-104
- Article: HUMAN REPRODUCTION OPEN. 2024;2024(2):hoae027
- Article: ANNALS OF ONCOLOGY. 2023;34(10):849-866
- Article: BRITISH JOURNAL OF CANCER. 2023;129(5):819-828
- Article: THE LANCET REGIONAL HEALTH. EUROPE. 2023;31:100680
- Article: ACTA ONCOLOGICA. 2023;62(3):215-222
- Article: BRITISH JOURNAL OF SURGERY. 2023;110(3):344-352
- Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2023;131(2):27003
- Article: ACTA ONCOLOGICA. 2022;61(12):1481-1489
- Article: BRITISH JOURNAL OF SURGERY. 2022;109(11):1107-1115
- Article: LEUKEMIA. 2022;36(10):2461-2467
- Article: BRITISH JOURNAL OF SURGERY. 2022;109(10):977-983
- Article: EUROPEAN JOURNAL OF CANCER. 2022;172:76-84
- Article: INTERNATIONAL JOURNAL OF CANCER. 2022;151(3):381-395
- Article: ACTA ONCOLOGICA. 2022;61(6):764-772
- Article: JAMA PSYCHIATRY. 2022;79(2):133-142
- Article: BREAST CANCER RESEARCH. 2022;24(1):4
- Article: ANDROLOGY. 2021;9(6):1773-1780
- Article: EUROPEAN JOURNAL OF CANCER. 2021;155:106-115
- Article: JAMA SURGERY. 2021;156(7):628-637
- Article: PEDIATRICS. 2021;148(1):e2020033183
- Article: BREAST CANCER RESEARCH. 2021;23(1):17
- Article: BJS OPEN. 2021;5(1):zraa013
- Article: BRITISH JOURNAL OF CANCER. 2020;123(11):1608-1615
- Article: ACTA ONCOLOGICA. 2020;59(11):1284-1290
- Article: ACTA ONCOLOGICA. 2020;59(11):1266-1274
- Article: BREAST CANCER RESEARCH AND TREATMENT. 2020;182(3):699-707
- Article: BREAST CANCER RESEARCH AND TREATMENT. 2020;182(2):477-489
- Article: JOURNAL OF AMERICAN ACADEMY OF DERMATOLOGY. 2020;82(5):1109-1116
- Article: FERTILITY AND STERILITY. 2020;113(3):524-532
- Article: CLINICAL GENITOURINARY CANCER. 2020;18(1):26-34.e6
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2019;34(11):1093-1101
- Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2019;48(5):1701-1709
- Article: BREAST. 2019;45:48-55
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2019;34(5):499-507
- Article: BREAST CANCER RESEARCH AND TREATMENT. 2019;174(2):489-503
- Article: CLINICAL EPIDEMIOLOGY. 2019;11:645-657
- Article: PLOS ONE. 2019;14(6):e0219206
- Article: JOURNAL OF CLINICAL ONCOLOGY. 2018;36(26):2718-2725
- Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2018;27(9):1065-1074
- Article: INTERNATIONAL JOURNAL OF CANCER. 2018;142(7):1343-1354
- Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2018;97(3):258-268
- Article: EUROPEAN JOURNAL OF CANCER. 2017;84:130-140
- Article: GASTROENTEROLOGY. 2017;153(3):702-710
- Article: FERTILITY AND STERILITY. 2017;108(1):137-144
- Article: JAMA PSYCHIATRY. 2017;74(6):589-596
- Article: INTERNATIONAL JOURNAL OF CANCER. 2017;140(4):841-852
- Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2017;72(1):134-139
- Article: BRITISH JOURNAL OF CANCER. 2016;115(11):1400-1407
- Article: CLINICAL CANCER RESEARCH. 2016;22(21):5249-5255
- Article: MEDICINE (UNITED KINGDOM). 2016;95(30):e4337
- Article: JOURNAL OF INFECTION. 2016;72(6):650-658
- Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(5):862-866
- Article: BREAST CANCER RESEARCH. 2016;18(1):36
- Article: JOURNAL OF CLINICAL ONCOLOGY. 2016;34(4):337-344
- Article: CANCER. 2015;121(12):2072-2077
- Article: BREAST CANCER RESEARCH AND TREATMENT. 2015;151(1):209-217
- Article: INTERNATIONAL JOURNAL OF CANCER. 2015;136(5):1171-1180
- Article: INTERNATIONAL JOURNAL OF CANCER. 2015;136(2):350-359
- Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2014;211(6):681.e1-681.e7
- Article: JOURNAL OF AMERICAN ACADEMY OF DERMATOLOGY. 2014;71(6):1093-1101
- Article: BRITISH JOURNAL OF CANCER. 2014;110(5):1378-1384
- Article: THE BMJ. 2014;348:g130
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2014;29(1):49-56
- Article: BREAST CANCER RESEARCH AND TREATMENT. 2013;139(1):183-192
- Article: EUROPEAN UROLOGY. 2013;63(4):733-738
- Article: LAKARTIDNINGEN. 2013;110(8):416-419
- Article: STATISTICAL SCIENCE. 2012;27(3):395-411
- Article: PLOS ONE. 2012;7(10):e46535
- Article: NEUROEPIDEMIOLOGY. 2012;38(3):186-193
- Article: INTERNATIONAL UROGYNECOLOGY JOURNAL. 2012;23(1):43-48
- Article: PARKINSONISM AND RELATED DISORDERS. 2011;17(9):677-682
- Article: JOURNAL OF CLINICAL ONCOLOGY. 2011;29(30):4014-4021
- Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2011;20(9):1865-1872
- Article: ACTA ONCOLOGICA. 2011;50(3):367-372
- Article: EUROPEAN HEART JOURNAL. 2011;32(6):745-750
- Article: PLOS ONE. 2011;6(2):e16885
- Article: ARCHIVES OF INTERNAL MEDICINE (CHICAGO, ILL. : 1908). 2010;170(22):2011-2016
- Article: BRITISH JOURNAL OF SURGERY. 2010;97(2):251-257
- Article: PEDIATRICS. 2009;124(5):e817-e825
- Article: OBSTETRICS AND GYNECOLOGY. 2009;114(3):594-599
- Article: OBSTETRICS AND GYNECOLOGY. 2009;114(3):568-572
- Article: EPIDEMIOLOGY. 2009;20(5):747-751
- Article: CANCER CAUSES AND CONTROL. 2009;20(7):1205-1214
- Article: EPIDEMIOLOGY. 2009;20(4):590-597
- Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2009;88(1):52-58
- Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2008;17(9):2344-2349
- Article: INTERNATIONAL JOURNAL OF CANCER. 2008;123(1):168-173
- Article: JOURNAL OF ORAL PATHOLOGY & MEDICINE. 2007;36(2):78-82
- Article: EPIDEMIOLOGY. 2006;17(5):500-505
- Article: INTERNATIONAL JOURNAL OF CANCER. 2006;119(2):392-397
- Article: PAEDIATRIC AND PERINATAL EPIDEMIOLOGY. 2006;20(2):119-126
- Article: OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 2006;63(2):107-112
- Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2006;85(11):1331-1337
- Article: EPIDEMIOLOGY AND INFECTION. 2005;133(4):645-652
- Article: CANCER CAUSES AND CONTROL. 2005;16(6):755-764
- Article: PSYCHONEUROENDOCRINOLOGY. 2005;30(6):558-567
- Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2005;14(7):1754-1761
- Article: OBSTETRICS AND GYNECOLOGY. 2004;104(4):720-726
- Article: LAKARTIDNINGEN. 2004;101(4):290-292
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2004;19(7):631-641
- Article: EPIDEMIOLOGY. 2003;14(2):218-222
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2003;18(6):539-544
- Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2002;288(15):1867-1873
- Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2001;30(6):1296-1301
- Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2001;184(3):463-469
- Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2000;284(20):2611-2617
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All other publications
- Conference publication: ISEE CONFERENCE ABSTRACTS. 2022;2022(1)
- Letter: JAMA SURGERY. 2022;157(2):174-175
- Letter: INTERNATIONAL JOURNAL OF CANCER. 2020;146(6):1767-1768
- Book chapter: DISEASES OF THE BREAST DURING PREGNANCY AND LACTATION: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2020;p. 75-79
- Review: ANNALS OF ONCOLOGY. 2019;30(10):1601-1612
- Published conference paper: INTERNATIONAL JOURNAL OF CANCER. 2019;144(6):1251-1261
- Thesis / dissertation: 2016
- Review: NEUROEPIDEMIOLOGY. 2014;42(2):69-80
- Letter: EUROPEAN UROLOGY. 2013;64(4):e81
- Letter: EPIDEMIOLOGY. 2010;21(6):919
- Published conference paper: STATISTICS IN MEDICINE. 2005;24(24):4045-4054
- Letter: OBSTETRICS AND GYNECOLOGY. 2005;105(2):444-445
Grants
- Senior Investigator AwardSwedish Cancer Society1 July 2024 - 30 June 2030
- Project GrantSwedish Cancer Society1 January 2023 - 31 December 2025
- Project GrantRadiumhemmet Research Foundations1 January 2023 - 31 December 2025
- Project GrantSwedish Breast Cancer Association1 January 2023 - 31 December 2024
- Starting GrantSwedish Research Council1 January 2022 - 31 December 2025
- COVID-19 and cancer: A registry study in the Nordic countriesNordic Cancer Union1 January 2021 - 31 December 2022
- Project GrantRadiumhemmet Research Foundations1 January 2020 - 31 December 2021
Employments
- Statistician, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 1999-
- Assistant Professor, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2021-2027
Degrees and Education
- Docent, Karolinska Institutet, 2022
- Degree Of Doctor Of Philosophy, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2016
- MSc, Mathematical Statistics, Stockholm University, 1999
Supervisor
- Frida Lundberg, 2018
- Roxanna Hellgren, Beyond mammography: an evaluation of complementary modalities in breast imaging
- Leo Gkekos
- Katrín Gunnarsdóttir