Anda Gliga

Anda Gliga

Research Specialist | Assistant Professor | Docent
Visiting address: Nobels väg 13, 17177 Stockholm
Postal address: C6 Institutet för miljömedicin, C6 Metaller och hälsa Broberg, 171 77 Stockholm

About me

  • I am Assistant Professor in toxicology at the Institute of Environmental Medicine. My research is focused on understanding mechanisms of particle toxicity. We have ongoing projects on the following types of particles:

    • welding particles (mild and stainless steel welding)
    • particles generated from combustion of renewable fuels such as biodiesel
    • particles generated from combustion of solid fuels of relevance for sub-Saharan Africa
    • fire emission particles from new ‘green’ materials

    In my research I combine in vitro models, in vitro-in vivo correlations, bioinformatics and molecular epidemiology approaches. 
    I am also a teacher, tutor and course leader within the Master's Programme in Toxicology, and union representative (Saco-S) at IMM.

Articles

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Grants

  • Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
    1 January 2022 - 31 December 2025
    The development of novel renewable fuels is paramount for reducing carbon emissions and mitigating climate change. Biofuels, such as biodiesel and lignin-based fuels could play an important role for this endeavour, particularly in Sweden. However, particles generated from combustion of such fuels could have a negative impact on human health, similar to traditionally used fuel. Knowledge on these aspects is scarce. The aim of this project is to evaluate lung toxicity of particles generated from combustion of novel biofuels such as ‘new generation’ biodiesel and lignin-based fuels that are originating from raw forest material. To this end the project will use advanced 3D in vitro models of the human lungs and experimental setups that resemble human exposure, i.e. acute and chronic exposure (3 months) at low, realistic doses. Traditional toxicological endpoints (e.g. inflammation, DNA damage) will be combined with RNA-sequencing in order to gain deep insight into potential mechanisms of toxicity and generate new hypotheses. We will also use 3D models representative of vulnerable populations such as individuals with asthma. The 3D models will be co-cultured with immune cells to evaluate the influence of the immune component for toxicity. Diesel exhaust particles will be used as reference particles for benchmarking. Overall, this project will provide relevant information on the toxicity of novel fuels that is of critical value for risk assessment and sustainable development.
  • Swedish Research Council for Health Working Life and Welfare
    1 January 2018 - 31 December 2019
  • Swedish Research Council for Health Working Life and Welfare
    1 December 2017 - 30 November 2020

Employments

  • Research Specialist, Institute of Environmental Medicine, Karolinska Institutet, 2021-
  • Assistant Professor, Institute of Environmental Medicine, Karolinska Institutet, 2022-2028

Degrees and Education

  • Docent, Karolinska Institutet, 2024
  • Degree Of Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2016
  • Degree Of Master Of Medical Science 120 Credits, Karolinska Institutet, 2012

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