Aditya Soni

I am a curious and driven molecular biologist with a passion for understanding biology at its most fundamental level where molecules, cells, and systems intersect to reveal new mechanisms and therapeutic possibilities.
My foundation in Molecular Biology, built across academia and biopharma gave me a deep appreciation for the complexity of biological systems. I see biological systems as an interconnected cosmos where intricate and complex questions remains unanswered.
At AstraZeneca, I worked as a scientist within Discovery Sciences, contributing to early research and drug discovery across assay development, compound screening, and mechanistic biology. This experience sharpened my expertise in cell-based assays, protein biochemistry, and high-throughput screening, while learning how to translate molecular insights into potential medicines.
I am now embarking on a PhD in Pharmacology and Physiology at Karolinska Institutet, where I will investigate orphan GPCRs in cancer biology using biosensors and AI-driven approaches. This next chapter brings together my love for mechanistic biology, my industry experience in functional assays, and my growing interest in how emerging technologies can accelerate our understanding of receptor signaling in disease.
I thrive in intellectually rigorous, collaborative environments where curiosity, communication and creative problem-solving is valued. My goal is to do meaningful science that deepens our understanding of life and contributes to better outcomes for human health.

I study GPCRs, a large family of cell surface receptors that mediate communication between cells. My work focuses on orphan GPCRs, receptors whose biological roles are still largely unknown. Using molecular biology, genome editing, proximity labeling (APEX2), and proteomics, I investigate how these receptors interact with cellular proteins and signaling pathways. My current project is developing an APEX2-based platform to characterize the interactomes of orphan GPCRs and generate new hypotheses about their physiological functions and relevance to human disease.