The Ulf von Euler lecture
The Ulf von Euler Lecture is an official annual named lecture of Karolinska Institutet. It was instituted by decision of the faculty at KI upon an initiative taken by Ulf von Euler's former students at the time of his passing away in 1983.
About the lecture
The intention of the lecture is that it should be given on a subject from one of the fields where Ulf von Euler made major contributions or a field where he today would have taken an interest, were he still alive and active.
It was made possible by forming a foundation, The Ulf von Euler Lectureship Foundation, which stems from donations by Ulf's family and friends and by generous donations from industry. The founders were Lennart Stjärne, Per Hedqvist, Åke Wennmalm and Hugo Lagercrantz.
Ulf von Euler
Ulf von Euler made major contributions to Science in the area of neuroscience, notably his Nobel prize awarded discovery of noradrenaline, in neuropeptide research by the discovery of substance P, and in lipid pharmacology by the discovery of prostaglandin.
The Euler-Liljestrand mechanism of regulation of pulmonary blood flow stemmed from research on muscular exercise effects on blood flow. A personal account of Ulf von Euler's life has been given by Hermann Blaschko.
The 2019 Ulf von Euler Lecturer
Dr. John H. Krystal, M.D.
"Rapid Acting Antidepressants: The path to ketamine and beyond"
Dr. Krystal is the Robert L. McNeil, Jr. Professor of Translational Research, Professor of Psychiatry, Neuroscience, and Psychology, Chair of the Department of Psychiatry at Yale University and Chief of Psychiatry and Behavioral Health at Yale-New Haven Hospital.
His laboratory works on the neurobiology and treatment of schizophrenia, alcoholism, PTSD, and depression and has discovered the rapid antidepressant effects of ketamine in humans.
Date, time and venue:
18 October 2019 at 14:00 in Conference room J3:07 Sune Bergström, Solnavägen 30, Solna.
Previous lecturers 2018-1985
|2018||Susan S. Taylor||"Lessons learned from PKA: From molecules to cells"|
|2017||Gregg L. Semenza||"Molecular Mechanisms of Oxygen Homeostatis"||2019 Nobel Prize in Physiology or Medicine together with William G. Kaelin Jr. and Sir Peter J. Ratcliffe “for their discoveries of how cells sense and adapt to oxygen availability”|
|2016||Sadaf Farooqi||"Obesity: neural mechanisms involved in eating behavior"|
|2015||Andrew R Marks||"Towards a structural basis of complex disorders of heart, muscle and brain"|
|2014||Susan G Amara||"A New Take on Uptake: Neurotransmitter transporters and the cellular mechanisms of amphetamine action"|
|2013||Bruce Spiegelman||"Brown and Beige Fat: Basic Biology and Novel Therapeutics"|
|2012||Masashi Yanagisawa, and Tsukuba||"From Novel Bioactive Peptides to Therapeutic Targets -- Journey on Endothelin and Orexin"|
|2010||Timothy J Williams||"Discovery of Eotaxin"|
|2005||Garret A Fitzgerald||"Lessons in drug development from the arachidonic acid cascade"|
|2004||Thoms Südhof||"How calcium triggers neurotransmitter release"||2013 Nobel Prize in Physiology or Medicine together with James E. Rothman and Randy W. Schekman “for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells”|
|2003||Solomon H Snyder||"Strange signaling in the brain"|
|2001||Warren M Zapol||"Oxygenation of the blood: Experience from antarctic seals, knockout mice and ARDS"|
|2000||Peter Agre||"Aquaporin water channel proteins: Nature´s plumbing system in mammals, microbes and plants"||2003 Nobel Prize in Chemistry together with Roderick MacKinnon “for discoveries concerning channels in cell membranes”|
|1999||Linda Buck||"Deconstructing Smell"||2004 Nobel Prize in Physiology or Medicine together with Richard Axel “for their discoveries of odorant receptors and the organization of the olfactory system”|
|1998||Richard Palmiter||"Life without noradrenaline"|
|1997||Paul Patterson||"Cytokine regulation of neuronal gene expression and the neuroimmune response to injury"|
|1996||John A Clements||"The roles of pulmonary surfactant in lung function"|
|1995||Thomas M Jessell||"Genetic control of neural cell fate in vertebrates"|
|1994||Raphael Mechoulam||“The long, unpaved road to a family of endogenous cannabinoid ligands - the anandamides”|
|1993||Philippe Ascher||"Modulations of the NMDA glutamate receptor"|
|1992||Robert J Lefkowitz||"The molecular biology and physiology of adrenoceptors"||2012 Nobel Prize in Chemistry together with Brian K. Kobilka “for studies of G-protein-coupled receptors”|
|1991||Salvador Moncada||"The discovery and biological significance of the L-arginine nitric oxide pathway"|
|1990||G C Liggins||"Prostanoids and parturition"|
|1989||Robert F Furchgott||"Present status of the endothelium-derived relaxing factor"||1998 Nobel Prize in Physiology or Medicine Together with Louis J. Ignarro and Ferid Murad href="https://www.nobelprize.org/prizes/medicine/1998/summary/">“for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular system”|
|1988||Fred Lembeck||"Substance P: From extract to excitement”"|
|1987||Rodolfo R Llinas||"What can single cell electrophysiology tell us about global brain function? Lessons from the cerebellum"|
|1986||Eric R Kandel||"Cell and molecular biological approaches to learning: On the relationship between short-term and long-term memory"||2000 Nobel Prize in Physiology or Medicine Together with Arvid Carlsson and Paul Greengard href="https://www.nobelprize.org/prizes/medicine/2000/summary/">“for their discoveries concerning signal transduction in the nervous system”|
|1985||Geoffrey Burnstock||"The Changing Face of Autonomic Neurotransmission"|