PET Scan at BMIC

The BMIC core facility offers Positron Emission Tomography (PET) scans with two different types of PET scanners.

PET Scan

PET images are always tomographic, meaning that PET scanner acquires 3D volumetric data.  A single set of 3D data is often referred to as a Static PET scan. Static images, as the name imply, gives information of the average uptake of radioactivity in the imaged region under a finite time; Hence, no information regarding the kinetics in that specific region can be extracted. Dynamic 3D PET (4D PET) acquisitions are performed to obtain time depended parameters needed for modelling of tissue kinetics.

PET Scanners at BMIC

At the BMIC we have two different PET scanners. The High Resolution Research Tomograph (HRRT) and the MultiScan™ LFER  150 (Large Field of view Extreme Resolution).

High Resolution Research Tomograph (HRRT) 

HRRT (Siemens Medical Solutions, USA) is a high resolution PET system dedicated for human brain imaging but can also be used for animal imaging such as primates. 

HRRT PET scanner
HRRT PET scanner at BMIC. Photo: Martin Bolin

Specifications:

Transaxial FOV: 31.2 cm

Axial FOV: 25.2 cm

Detector crystal: Double layer LSO-LYSO (2.1 x 2.1 x 7.5) mm

Spatial resolution: ~ 2.5 mm

Sensitivity: ~ 3 %

MultiScan™ LFER 150 PET/CT

MultiScan™ LFER 150 PET/CT (Mediso Medical Imaging Systems, Hungary) is a pre-clinical PET system dedicated for animal imaging with exceptional spatial resolution for quantitative analysis of small structures.

LFER 150 PET/CT
LFER 150 PET/CT scanner at BMIC. Photo: Zsolt Sarnyai

Specifications:

Gantry opening: 26 cm

Transaxial FOV: 20 cm

Axial FOV: 15 cm

Animal models: Up to 16 kg Rhesus or 4 mice simultaneously

Detector crystal: LYSO (1.51 x 1.51 x 10) mm 

Spatial resolution: ~ 1 mm

Sensitivity: ~ 5 %

Noise Equivalent Count Rate for monkey (NEMA): 64.7 kcps @ 128 MBq