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Exploring sulfonate esters of 5-arylidene thiazolidine-2,4-diones as PTP1B inhibitors with anti-hyperglycemic activity
Mahapatra Mk, Kumar R, Kumar M
MEDICINAL CHEMISTRY RESEARCH 2018;27(2):476-487

In silico modelling and molecular dynamics simulation studies of thiazolidine based PTP1B inhibitors
Mahapatra Mk, Bera K, Singh Dv, Kumar R, Kumar M
Journal of biomolecular structure & dynamics 2018;36(5):1195-1211

Amyloid beta peptides act as allosteric modulators of cholinesterases
Kumar R, Darreh-shori T
JOURNAL OF NEUROCHEMISTRY 2017;:214-214

Combined x-ray crystallography and computational modeling approach to investigate the Hsp90 C-terminal peptide binding to FKBP51
Kumar R, Moche M, Winblad B, Pavlov Pf
Scientific reports 2017;7(1):14288-

Discovery of novel choline acetyltransferase inhibitors using structure-based virtual screening
Kumar R, Kumar A, Långström B, Darreh-shori T
Scientific reports 2017;7(1):16287-

N-alkylated thiazolidine-2,4-dione analogs as PTP1B inhibitors: synthesis, biological activity, and docking studies
Mahapatra Mk, Kumar R, Kumar M
MEDICINAL CHEMISTRY RESEARCH 2017;26(6):1176-1183

Synthesis, biological evaluation and in silico studies of 5-(3-methoxybenzylidene)thiazolidine-2,4-dione analogues as PTP1B inhibitors
Mahapatra Mk, Kumar R, Kumar M
Bioorganic chemistry 2017;71():1-9

Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs
Kumar R, Nordberg A, Darreh-shori T
Brain : a journal of neurology 2016;139(Pt 1):174-92

Evaluation of potential flavonoid inhibitors of glyoxalase-I based on virtual screening and in vitro studies
Yadav A, Kumar R, Sunkaria A, Singhal N, Kumar M, Sandhir R
Journal of biomolecular structure & dynamics 2016;34(5):993-1007

Novel ligands of Choline Acetyltransferase designed by in silico molecular docking, hologram QSAR and lead optimization
Kumar R, Långström B, Darreh-shori T
Scientific reports 2016;6():31247-

Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors
Aggarwal S, Mahapatra Mk, Kumar R, Bhardwaj Tr, Hartmann Rw, Haupenthal J, et al
Bioorganic & medicinal chemistry 2016;24(4):779-88

Synthesis, Biological Evaluation and in silico Studies of Novel 5-aza-B-homo-3,5-secosteroids as Potential 5 alpha-reductase Inhibitors
Kumar R, Chauhan P, Malla P, Mahapatra Mk, Hartmann Rw, Haupenthal J, et al
LETTERS IN DRUG DESIGN & DISCOVERY 2016;13(9):869-878

Zingerone silences quorum sensing and attenuates virulence of Pseudomonas aeruginosa
Kumar L, Chhibber S, Kumar R, Kumar M, Harjai K
Fitoterapia 2015;102():84-95

A paradigm for development of novel PTP 1B inhibitors: Pharmacophore modelling, atom-based 3D-QSAR and docking studies
Malla P, Kumar R, Mattewal Sk, Mahapatra Mk, Kumar M
MEDICINAL CHEMISTRY RESEARCH 2014;23(2):927-938

In silico accounting of novel pyridazine analogues as h-PTP 1B inhibitors: pharmacophore modelling, atom-based 3D QSAR and docking studies
Mahapatra Mk, Kumar R, Malla P, Kumar M
MEDICINAL CHEMISTRY RESEARCH 2014;23(6):2701-2711

Ramping Glucosuria for Management of Type 2 Diabetes Mellitus: An Emerging Cynosure
Malla P, Kumar R, Mahapatra Mk, Kumar M
MEDICINAL RESEARCH REVIEWS 2014;34(6):1146-67

3D-QSAR CoMFA and CoMSIA studies for design of potent human steroid 5 alpha-reductase inhibitors
Kumar R, Kumar M
MEDICINAL CHEMISTRY RESEARCH 2013;22(1):105-114

Advances in the design and discovery of drugs for the treatment of prostatic hyperplasia
Kumar R, Malla P, Kumar M
Expert opinion on drug discovery 2013;8(8):1013-27

Design and synthesis of potential 5 alpha-reductase inhibitors for the management of benign prostaic hyperplasia
Kumar R, Kumar M
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2013;:-

Design of potent human steroid 5 alpha-reductase inhibitors: 3D-QSAR CoMFA, CoMSIA and docking studies
Kumar R, Malla P, Verma A, Kumar M
MEDICINAL CHEMISTRY RESEARCH 2013;22(10):4568-4580

Ezogabine: Development and Role in the Management of Epileptic Seizures
Verma A, Kumar R, Kumar M
MINI-REVIEWS IN MEDICINAL CHEMISTRY 2013;13(5):697-705

Pharmacophore Modeling, Atom Based 3D-QSAR and Docking Studies of Protein Tyrosine Phosphatase 1B Inhibitors
Malla P, Kumar R, Kumar M
LETTERS IN DRUG DESIGN & DISCOVERY 2013;10(4):303-319

Validation of Formylchromane Derivatives as Protein Tyrosine Phosphatase 1B Inhibitors by Pharmacophore Modeling, Atom-Based 3D-QSAR and Docking Studies
Malla P, Kumar R, Kumar M
CHEMICAL BIOLOGY & DRUG DESIGN 2013;82(1):71-80

Accounting of ligand-receptor interactions to explore and design novel architecture for PTP 1B inhibition: a legitimate approach
Malla P, Kumar R, Kumar M
JOURNAL OF CHEMOMETRICS 2012;26(11-12):576-584

Pharmacological screening for anti-inflammatory, analgesic activity of pyrazolyl derivatives along with molecular docking studies
Kaushik D, Kumar R, Khan Sa, Chawla G
MEDICINAL CHEMISTRY RESEARCH 2012;21(11):3646-3655

Synthesis, antibacterial evaluation and QSAR studies of 7-[4-(5-aryl-1,3,4-oxadiazole-2-yl)piperazinyl] quinolone derivatives
Kumar R, Kumar A, Jain S, Kaushik D
European journal of medicinal chemistry 2011;46(9):3543-50

QSAR studies of benzofuran/benzothiophene biphenyl derivatives as inhibitors of PTPase-1B
Kaushik D, Kumar R, Saxena Ak
Journal of pharmacy & bioallied sciences 2010;2(1):27-31

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