Noémi Van Hul

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: EMBO MOLECULAR MEDICINE. 2022;14(12):e15809

Sex differences and risk factors for bleeding in Alagille syndrome.

Hankeova S; Van Hul N; Laznovsky J; Verboven E; Mangold K; Hensens N; Adori C; Verhoef E; Zikmund T; Dawit F; Kavkova M; Salplachta J; Sjöqvist M; Johansson BR; Hassan MG; Fredriksson L; Baumgärtel K; Bryja V; Lendahl U; Jheon A; Alten F; Fahnehjelm KT; Fischler B; Kaiser J; Andersson ER
Article: NATURE COMMUNICATIONS. 2021;12(1):7046

Spatial Transcriptomics to define transcriptional patterns of zonation and structural components in the mouse liver.

Hildebrandt F; Andersson A; Saarenpää S; Larsson L; Van Hul N; Kanatani S; Masek J; Ellis E; Barragan A; Mollbrink A; Andersson ER; Lundeberg J; Ankarklev J
Article: TRANSGENIC RESEARCH. 2021;30(5):701-707

Severe liver disease resembling PSC in mice with K5-Cre mediated deletion of Krüppel-like factor 5 (Klf5).

Bergström Å; Gerling M; Van Hul N; Fernández Moro C; Rozell B; Toftgård R; Sur I
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2021;(175)

DUCT: Double Resin Casting followed by Micro-Computed Tomography for 3D Liver Analysis.

Hankeova S; Salplachta J; Van Hul N; Kavkova M; Iqbal A; Zikmund T; Kaiser J; Andersson ER
Article: SCIENCE SIGNALING. 2021;14(688):eaay9185

Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation.

Minnis-Lyons SE; Ferreira-González S; Aleksieva N; Man TY; Gadd VL; Williams MJ; Guest RV; Lu W-Y; Dwyer BJ; Jamieson T; Nixon C; Van Hul N; Lemaigre FP; McCafferty J; Leclercq IA; Sansom OJ; Boulter L; Forbes SJ
Article: GASTROENTEROLOGY. 2021;160(6):2103-2118

Protective Functions of ZO-2/Tjp2 Expressed in Hepatocytes and Cholangiocytes Against Liver Injury and Cholestasis.

Xu J; Kausalya PJ; Van Hul N; Caldez MJ; Xu S; Ong AGM; Woo WL; Mohamed Ali S; Kaldis P; Hunziker W
Article: ELIFE. 2021;10:e60916

DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome.

Hankeova S; Salplachta J; Zikmund T; Kavkova M; Van Hul N; Brinek A; Smekalova V; Laznovsky J; Dawit F; Jaros J; Bryja V; Lendahl U; Ellis E; Nemeth A; Fischler B; Hannezo E; Kaiser J; Andersson ER
Article: PLOS GENETICS. 2020;16(11):e1009084

Loss of hepatocyte cell division leads to liver inflammation and fibrosis.

Dewhurst MR; Ow JR; Zafer G; van Hul NKM; Wollmann H; Bisteau X; Brough D; Choi H; Kaldis P
Article: NATURE MATERIALS. 2020;19(9):1026-1035

Biomimetic niches reveal the minimal cues to trigger apical lumen formation in single hepatocytes.

Zhang Y; De Mets R; Monzel C; Acharya V; Toh P; Chin JFL; Van Hul N; Ng IC; Yu H; Ng SS; Tamir Rashid S; Viasnoff V
Article: JOURNAL OF INTERNAL MEDICINE. 2020;287(5):534-545

Regulation of bile acid metabolism in biliary atresia: reduction of FGF19 by Kasai portoenterostomy and possible relation to early outcome.

Johansson H; Svensson JF; Almström M; Van Hul N; Rudling M; Angelin B; Nowak G; Fischler B; Ellis E
Article: AMERICAN JOURNAL OF PATHOLOGY. 2019;189(8):1569-1581

Invasive Ductular Reaction Operates Hepatobiliary Junctions upon Hepatocellular Injury in Rodents and Humans.

Clerbaux L-A; Manco R; Van Hul N; Bouzin C; Sciarra A; Sempoux C; Theise ND; Leclercq IA
Article: ONCOGENE. 2019;38(7):998-1018

Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality.

Szmyd R; Niska-Blakie J; Diril MK; Renck Nunes P; Tzelepis K; Lacroix A; van Hul N; Deng L-W; Matos J; Dreesen O; Bisteau X; Kaldis P
Article: FRONTIERS IN MEDICINE. 2019;6:179

IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis.

Czepukojc B; Abuhaliema A; Barghash A; Tierling S; Naß N; Simon Y; Körbel C; Cadenas C; van Hul N; Sachinidis A; Hengstler JG; Helms V; Laschke MW; Walter J; Haybaeck J; Leclercq I; Kiemer AK; Kessler SM
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1981:203-236

Mouse Models for Diseases in the Cholangiocyte Lineage.

Van Hul N; Lendahl U; Andersson ER
Article: DEVELOPMENTAL CELL. 2018;47(4):425-438.e5

Metabolic Remodeling during Liver Regeneration.

Caldez MJ; Van Hul N; Koh HWL; Teo XQ; Fan JJ; Tan PY; Dewhurst MR; Too PG; Talib SZA; Chiang BE; Stünkel W; Yu H; Lee P; Fuhrer T; Choi H; Björklund M; Kaldis P
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2017;101(3):391-403

CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.

Windpassinger C; Piard J; Bonnard C; Alfadhel M; Lim S; Bisteau X; Blouin S; Ali NB; Ng AYJ; Lu H; Tohari S; Talib SZA; van Hul N; Caldez MJ; Van Maldergem L; Yigit G; Kayserili H; Youssef SA; Coppola V; de Bruin A; Tessarollo L; Choi H; Rupp V; Roetzer K; Roschger P; Klaushofer K; Altmüller J; Roy S; Venkatesh B; Ganger R; Grill F; Ben Chehida F; Wollnik B; Altunoglu U; Al Kaissi A; Reversade B; Kaldis P
Article: PLOS ONE. 2016;11(9):e0162286

Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies.

Best J; Verhulst S; Syn W-K; Lagaisse K; van Hul N; Heindryckx F; Sowa J-P; Peeters L; Van Vlierberghe H; Leclercq IA; Canbay A; Dollé L; van Grunsven LA
Article: CELL TRANSPLANTATION. 2015;24(12):2557-2571

Hepatic Stellate Cells Improve Engraftment of Human Primary Hepatocytes: A Preclinical Transplantation Study in an Animal Model.

Dusabineza A-C; Najimi M; van Hul N; Legry V; Khuu DN; van Grunsven LA; Sokal E; Leclercq IA
Article: GASTROENTEROLOGY. 2012;143(6):1564-1575.e7

Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice.

Español-Suñer R; Carpentier R; Van Hul N; Legry V; Achouri Y; Cordi S; Jacquemin P; Lemaigre F; Leclercq IA
Article: LABORATORY INVESTIGATION. 2012;92(1):72-81

Participation of liver progenitor cells in liver regeneration: lack of evidence in the AAF/PH rat model.

Dusabineza A-C; Van Hul NK; Abarca-Quinones J; Starkel P; Najimi M; Leclercq IA
Article: AMERICAN JOURNAL OF PATHOLOGY. 2011;179(4):1839-1850

Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury.

Van Hul N; Lanthier N; Español Suñer R; Abarca Quinones J; van Rooijen N; Leclercq I
Article: GASTROENTEROLOGY. 2011;141(4):1432-1438.e4

Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells.

Carpentier R; Suñer RE; van Hul N; Kopp JL; Beaudry J-B; Cordi S; Antoniou A; Raynaud P; Lepreux S; Jacquemin P; Leclercq IA; Sander M; Lemaigre FP
Article: HEPATOLOGY. 2009;49(5):1625-1635

Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.

Van Hul NKM; Abarca-Quinones J; Sempoux C; Horsmans Y; Leclercq IA
Article: LABORATORY INVESTIGATION. 2006;86(11):1161-1171

Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin.

Leclercq IA; Vansteenberghe M; Lebrun VB; VanHul NK; Abarca-Quinones J; Sempoux CL; Picard C; Stärkel P; Horsmans YL
Article: GENOMICS. 2005;85(5):574-581

Distribution of human beta-defensin polymorphisms in various control and cystic fibrosis populations.

Vankeerberghen A; Scudiero O; De Boeck K; Macek M; Pignatti PF; Van Hul N; Nuytten H; Salvatore F; Castaldo G; Zemkova D; Vavrova V; Cassiman J-J; Cuppens H
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Corrigendum: ONCOGENE. 2020;39(9):2030

Correction: Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality.

Szmyd R; Niska-Blakie J; Diril MK; Nunes PR; Tzelepis K; Lacroix A; van Hul N; Deng L-W; Matos J; Dreesen O; Bisteau X; Kaldis P
Meeting abstract: JOURNAL OF HEPATOLOGY. 2017;66(1):s6

Ductular reactions provide a structural biliary network to preserve bile drainage in the CDE-model of hepatocellular chronic liver injury

Clerbaux L-A; Manco R; Van Hul N; Espanol-Suner R; Bouzin C; Sempoux C; Theise N; Leclercq I
Meeting abstract: JOURNAL OF HEPATOLOGY. 2016;64:s203

FUELING CELLULAR DIVISION DURING LIVER REGENERATION: CDK1 REGULATES ENERGY METABOLISM BY DIRECTING THE FLUX OF PYRUVATE

Caldez M; Van Hul N; Teo XQ; Fuhrer T; Fan JJ; Tan PY; Stunkel W; Yu H; Bjorklund M; Sauer U; Lee P; Kaldis P
Meeting abstract: JOURNAL OF HEPATOLOGY. 2016;64:s638-s639

COMBINED DELETION OF HEPATIC ZO-1 AND ZO-2 INDUCES LOSS OF BILE DUCTS

Xu J; Van Hul N; Caldez M; Dewhurst M; Kaldis P; Hunziker W
Meeting abstract: JOURNAL OF HEPATOLOGY. 2016;64:s350

CDK1 KNOCK OUT GIANT HEPATOCYTES INDUCE LIVER PROGENITOR CELLS

Van Hul N; Caldez M; Kaldis P
Meeting abstract: JOURNAL OF HEPATOLOGY. 2015;62:s469

CELL CYCLE REGULATION IS DELAYED IN A MODEL OF LIVER REGENERATION AFTER SERIAL PARTIAL HEPATECTOMY

Caldez M; Van Hul N; Kaldis P
Meeting abstract: JOURNAL OF HEPATOLOGY. 2015;62:s465-s466

DELETION OF Cdk1 IN THE LIVER INDUCES CHANGES IN PYRUVATE METABOLISM

Caldez M; Teo XQ; Van Hul N; Lee P; Kaldis P
Meeting abstract: JOURNAL OF HEPATOLOGY. 2015;62:s407

THE INSULINE-LIKE GROWTH FACTOR 2 (IGF2) MRNA BINDING PROTEIN (IMP) P62 PROMOTES CIRRHOSIS-LINKED HEPATOCARCINOGENESIS

Kessler SM; Czepukojc B; Engel K; Van Hul N; Haybaeck J; Leclercq I; Kiemer AK
Meeting abstract: JOURNAL OF HEPATOLOGY. 2014;60(1):s101

ROLE OF TUMOR NECROSIS FACTOR-α DURING THE DUCTULAR REACTION IN MOUSE MODELS OF LIVER INJURY

Best J; Verhulst S; Van Hul N; Syn W-K; Heindryckx F; Van Vlierberghe H; Reynaert H; Leclercq IA; van Grunsven LA; Dolle L
Meeting abstract: JOURNAL OF HEPATOLOGY. 2012;56:s28

ADULT LIVER PROGENITOR CELLS DIFFERENTIATE TOWARD MATURE HEPATOCYTES AFTER CDE DIET-INDUCED INJURY

Suner RE; Carpentier R; Van Hul N; Lemaigre F; Leclercq I
Meeting abstract: JOURNAL OF HEPATOLOGY. 2009;50:s314

RELATION BETWEEN LIVER PROGENITOR CELL EXPANSION AND EXTRACELLULAR MATRIX DEPOSITION IN A CDE INDUCED MURINE MODEL OF CHRONIC LIVER INJURY

Van Hul N; Abarca-Quinones J; Sempoux C; Horsmans Y; Leclercq I
Review: JOURNAL OF HEPATOLOGY. 2007;47(1):142-156

Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences.

Leclercq IA; Da Silva Morais A; Schroyen B; Van Hul N; Geerts A

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