Lena Ström

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: LIFE SCIENCE ALLIANCE. 2022;5(5):e202101244

Recruitment of Scc2/4 to double-strand breaks depends on γH2A and DNA end resection.

Scherzer M; Giordano F; Ferran MS; Ström L
Article: PLOS GENETICS. 2021;17(9):e1009763

Deficiency of Polη in Saccharomyces cerevisiae reveals the impact of transcription on damage-induced cohesion.

Wu P-S; Grosser J; Cameron DP; Baranello L; Ström L
Article: GENETICS. 2020;216(4):1009-1022

Post-translational Regulation of DNA Polymerase η, a Connection to Damage-Induced Cohesion in Saccharomyces cerevisiae.

Wu P-S; Enervald E; Joelsson A; Palmberg C; Rutishauser D; Hällberg BM; Ström L
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;141(1):408-411.e8

Reduced immunoglobulin gene diversity in patients with Cornelia de Lange syndrome.

Björkman A; Du L; van der Burg M; Cormier-Daire V; Borck G; Pié J; Anderlid B-M; Hammarström L; Ström L; de Villartay J-P; Kipling D; Dunn Walters D; Pan-Hammarström Q
Article: JOURNAL OF CELL SCIENCE. 2017;130(6):1134-1146

Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage.

Bot C; Pfeiffer A; Giordano F; Manjeera DE; Dantuma NP; Ström L
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2017;18(3):E481-481

mRNA Quantification of NIPBL Isoforms A and B in Adult and Fetal Human Tissues, and a Potentially Pathological Variant Affecting Only Isoform A in Two Patients with Cornelia de Lange Syndrome.

Puisac B; Teresa-Rodrigo M-E; Hernández-Marcos M; Baquero-Montoya C; Gil-Rodríguez M-C; Visnes T; Bot C; Gómez-Puertas P; Kaiser FJ; Ramos FJ; Ström L; Pié J
Article: HUMAN MUTATION. 2015;36(4):454-462

De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes.

Gil-Rodríguez MC; Deardorff MA; Ansari M; Tan CA; Parenti I; Baquero-Montoya C; Ousager LB; Puisac B; Hernández-Marcos M; Teresa-Rodrigo ME; Marcos-Alcalde I; Wesselink J-J; Lusa-Bernal S; Bijlsma EK; Braunholz D; Bueno-Martinez I; Clark D; Cooper NS; Curry CJ; Fisher R; Fryer A; Ganesh J; Gervasini C; Gillessen-Kaesbach G; Guo Y; Hakonarson H; Hopkin RJ; Kaur M; Keating BJ; Kibaek M; Kinning E; Kleefstra T; Kline AD; Kuchinskaya E; Larizza L; Li YR; Liu X; Mariani M; Picker JD; Pié Á; Pozojevic J; Queralt E; Richer J; Roeder E; Sinha A; Scott RH; So J; Wusik KA; Wilson L; Zhang J; Gómez-Puertas P; Casale CH; Ström L; Selicorni A; Ramos FJ; Jackson LG; Krantz ID; Das S; Hennekam RCM; Kaiser FJ; FitzPatrick DR; Pié J
Article: JOURNAL OF IMMUNOLOGY. 2014;193(9):4732-4738

A novel mouse model for the hyper-IgM syndrome: a spontaneous activation-induced cytidine deaminase mutation leading to complete loss of Ig class switching and reduced somatic hypermutation.

Dahlberg CIM; He M; Visnes T; Torres ML; Cortizas EM; Verdun RE; Westerberg LS; Severinson E; Ström L
Article: CHROMOSOMA. 2014;123(3):239-252

Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase I.

Visnes T; Giordano F; Kuznetsova A; Suja JA; Lander AD; Calof AL; Ström L
Article: NATURE NEUROSCIENCE. 2014;17(6):801-803

The age and genomic integrity of neurons after cortical stroke in humans.

Huttner HB; Bergmann O; Salehpour M; Rácz A; Tatarishvili J; Lindgren E; Csonka T; Csiba L; Hortobágyi T; Méhes G; Englund E; Solnestam BW; Zdunek S; Scharenberg C; Ström L; Ståhl P; Sigurgeirsson B; Dahl A; Schwab S; Possnert G; Bernard S; Kokaia Z; Lindvall O; Lundeberg J; Frisén J
Article: CELL CYCLE. 2014;13(23):3645-3658

Inactivation of the budding yeast cohesin loader Scc2 alters gene expression both globally and in response to a single DNA double strand break.

Lindgren E; Hägg S; Giordano F; Björkegren J; Ström L
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2013;210(12):2503-2513

A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination.

Enervald E; Du L; Visnes T; Björkman A; Lindgren E; Wincent J; Borck G; Colleaux L; Cormier-Daire V; van Gent DC; Pie J; Puisac B; de Miranda NF; Kracker S; Hammarström L; de Villartay J-P; Durandy A; Schoumans J; Ström L; Pan-Hammarström Q
Article: PLOS GENETICS. 2013;9(1):e1003158

Importance of Polη for damage-induced cohesion reveals differential regulation of cohesion establishment at the break site and genome-wide.

Enervald E; Lindgren E; Katou Y; Shirahige K; Ström L
Article: NATURE. 2011;471(7338):392-396

Chromosome length influences replication-induced topological stress.

Kegel A; Betts-Lindroos H; Kanno T; Jeppsson K; Ström L; Katou Y; Itoh T; Shirahige K; Sjögren C
Article: SCIENCE. 2007;317(5835):242-245

Postreplicative formation of cohesion is required for repair and induced by a single DNA break.

Ström L; Karlsson C; Lindroos HB; Wedahl S; Katou Y; Shirahige K; Sjögren C
Article: CURRENT OPINION IN CELL BIOLOGY. 2007;19(3):344-349

Chromosome segregation and double-strand break repair - a complex connection.

Ström L; Sjögren C
Article: MOLECULAR CELL. 2006;22(6):755-767

Chromosomal association of the Smc5/6 complex reveals that it functions in differently regulated pathways.

Betts Lindroos H; Ström L; Itoh T; Katou Y; Shirahige K; Sjögren C
Article: CELL CYCLE. 2005;4(4):536-539

DNA damage-induced cohesion.

Ström L; Sjögren C
Article: MOLECULAR CELL. 2004;16(6):1003-1015

Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair.

Ström L; Lindroos HB; Shirahige K; Sjögren C
Article: MOLECULAR IMMUNOLOGY. 2003;39(13):771-782

Binding of Ikaros to germline Ig heavy chain gamma1 and epsilon promoters.

Ström L; Lundgren M; Severinson E
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1999;49(5):523-532

Characterization of CD40-dependent immunoglobulin class switching.

Ström L; Laurencikiené J; Miskiniené A; Severinson E
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1996;26(12):2911-2915

CD40 signaling induces interleukin-4-independent IgE switching in vivo.

Ferlin WG; Severinson E; Ström L; Heath AW; Coffman RL; Ferrick DA; Howard MC
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1995;25(7):2042-2051

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members.

Lundgren M; Ström L; Bergquist LO; Skog S; Heiden T; Stavnezer J; Severinson E
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Alla övriga publikationer

Review: CURRENT BIOLOGY. 2012;22(7):R240-R250

The ancient and evolving roles of cohesin in gene expression and DNA repair.

Dorsett D; Ström L
Other: CELL CYCLE. 2010;9(18):3644

Additional proof for the importance of Eco1 for DNA double strand break repair.

Ström L
Review: EXPERIMENTAL CELL RESEARCH. 2010;316(9):1445-1453

S-phase and DNA damage activated establishment of sister chromatid cohesion--importance for DNA repair.

Sjögren C; Ström L

Anställningar

Universitetslektor, Cell- och molekylärbiologi, Karolinska Institutet, 2017-

Examina och utbildning

Docent, Cell- och molekylärbiologi, Karolinska Institutet, 2015
MEDICINE DOKTORSEXAMEN, Institutionen för cell- och molekylärbiologi, Karolinska Institutet, 2002

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