Federico Pietrocola
Senior Forskare
E-postadress: federico.pietrocola@ki.se
Besöksadress: Solnavägen 9, 17165 Solna
Postadress: C5 Cell- och molekylärbiologi, C5 CMB Pietrocola, 171 77 Stockholm
Artiklar
- Journal article: JOURNAL OF TRANSLATIONAL MEDICINE. 2026;24(1):747Zubova A; Pietrocola F; Morsli S
- Article: SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2026;11(1):119Lambertucci F; Motino O; Nogueira-Recalde U; Rong Y; Montegut L; Perez-Lanzon M; Carbonnier V; Li S; Durand S; Aprahamian F; Chen H; Dong Y; Sauvat A; Mingoia S; Lachkar S; Saavedra E; Pol J; Pietrocola F; Maiuri MC; Rocha-Oliveira E; Roncon-Albuquerque R; Vasques-Novoa F; Lozano-Rodriguez R; Avendano-Ortiz J; Lopez-Collazo E; Abdellatif M; Martins I; Kroemer G
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2025;122(28):e2501584122Montegut L; Lambertucci F; Moledo-Nodar L; Fiuza-Luces C; Rodriguez-Lopez C; Serra-Rexach JA; Lachkar S; Motino O; Abdellatif M; Durand S; Aprahamian F; Carbonnier V; Le Corre D; Richard SM; Chen H; Sauvat A; Dong Y; Li S; Rong Y; Pietrocola F; Puig PL; Lopez-Otin C; Martins I; Barcena C; Lucia A; Kroemer G
- Article: CELL DEATH AND DIFFERENTIATION. 2025;32(3):434-446Motino O; Lambertucci F; Joseph A; Durand S; Anagnostopoulos G; Li S; Carbonnier V; Nogueira-Recalde U; Montegut L; Chen H; Aprahamian F; Nirmalathasan N; Maiuri MC; Pietrocola F; Valla D; Laouenan C; Gautier J-F; Castera L; Martins I; Kroemer G
- Article: TRANSLATIONAL RESEARCH. 2025;275:32-47Arefin S; Mudrovcic N; Hobson S; Pietrocola F; Ebert T; Ward LJ; Witasp A; Hernandez L; Wennberg L; Lundgren T; Steinmetz-Spah J; Larsson K; Thorell A; Bruno S; Marengo M; Cantaluppi V; Stenvinkel P; Kublickiene K
- Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024;25(14):7554Hernandez-Gonzalez F; Pietrocola F; Cameli P; Bargagli E; Prieto-Gonzalez S; Cruz T; Mendoza N; Rojas M; Serrano M; Agusti A; Faner R; Gomez-Puerta JA; Sellares J
- Journal article: NATURE COMMUNICATIONS. 2024;15(1):46Lim JS; Jeon EJ; Go HS; Kim H-J; Kim KY; Nguyen TQT; Lee DY; Kim KS; Pietrocola F; Hong SH; Lee SE; Kim K-S; Park T-S; Choi D-H; Jeong Y-J; Park J-H; Kim HS; Min J-J; Kim YS; Park JT; Cho J-H; Lee G-W; Lee JH; Choy HE; Park SC; Lee C-H; Rhee JH; Serrano M; Cho KA
- Article: ONCOIMMUNOLOGY. 2023;12(1):2154115Marin I; Serrano M; Pietrocola F
- Article: NATURE CELL BIOLOGY. 2023;25(12):1804-1820McHugh D; Sun B; Gutierrez-Munoz C; Hernandez-Gonzalez F; Mellone M; Guiho R; Duran I; Pombo J; Pietrocola F; Birch J; Kallemeijn WW; Khadayate S; Dharmalingam G; Vernia S; Tate EW; Martinez-Barbera JP; Withers DJ; Thomas GJ; Serrano M; Gil J
- Article: CELL STRESS. 2023;7(12):105-111Annunziata C; Castoldi F; Schlegel J; Ang HX; Ristovska M; Melini S; Welch R; Riedel CG; Pietrocola F
- Article: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 2023;34(11):2518-2524Marques C; Friedrich F; Liu L; Castoldi F; Pietrocola F; Lanekoff I
- Article: NATURE METABOLISM. 2023;5(11):1911-1930Kovatcheva M; Melendez E; Chondronasiou D; Pietrocola F; Bernad R; Caballe A; Junza A; Capellades J; Holguin-Horcajo A; Prats N; Durand S; Rovira M; Yanes O; Stephan-Otto Attolini C; Kroemer G; Serrano M
- Article: AGING-US. 2023;15(14):6641-6657Hernandez-Gonzalez F; Prats N; Ramponi V; Lopez-Dominguez JA; Meyer K; Aguilera M; Martin MIM; Martinez D; Agusti A; Faner R; Sellares J; Pietrocola F; Serrano M
- Review: BIOMEDICAL JOURNAL. 2023;46(3):100581Giannoula Y; Kroemer G; Pietrocola F
- Review: CELL DEATH AND DIFFERENTIATION. 2023;30(5):1097-1154Vitale I; Pietrocola F; Guilbaud E; Aaronson SA; Abrams JM; Adam D; Agostini M; Agostinis P; Alnemri ES; Altucci L; Amelio I; Andrews DW; Aqeilan RI; Arama E; Baehrecke EH; Balachandran S; Bano D; Barlev NA; Bartek J; Bazan NG; Becker C; Bernassola F; Bertrand MJM; Bianchi ME; Blagosklonny MV; Blander JM; Blandino G; Blomgren K; Borner C; Bortner CD; Bove P; Boya P; Brenner C; Broz P; Brunner T; Damgaard RB; Calin GA; Campanella M; Candi E; Carbone M; Carmona-Gutierrez D; Cecconi F; Chan FK-M; Chen G-Q; Chen Q; Chen YH; Cheng EH; Chipuk JE; Cidlowski JA; Ciechanover A; Ciliberto G; Conrad M; Cubillos-Ruiz JR; Czabotar PE; D'Angiolella V; Daugaard M; Dawson TM; Dawson VL; De Maria R; De Strooper B; Debatin K-M; Deberardinis RJ; Degterev A; Del Sal G; Deshmukh M; Di Virgilio F; Diederich M; Dixon SJ; Dynlacht BD; El-Deiry WS; Elrod JW; Engeland K; Fimia GM; Galassi C; Ganini C; Garcia-Saez AJ; Garg AD; Garrido C; Gavathiotis E; Gerlic M; Ghosh S; Green DR; Greene LA; Gronemeyer H; Haecker G; Hajnoczky G; Hardwick JM; Haupt Y; He S; Heery DM; Hengartner MO; Hetz C; Hildeman DA; Ichijo H; Inoue S; Jaeaettelae M; Janic A; Joseph B; Jost PJ; Kanneganti T-D; Karin M; Kashkar H; Kaufmann T; Kelly GL; Kepp O; Kimchi A; Kitsis RN; Klionsky DJ; Kluck R; Krysko DV; Kulms D; Kumar S; Lavandero S; Lavrik IN; Lemasters JJ; Liccardi G; Linkermann A; Lipton SA; Lockshin RA; Lopez-Otin C; Luedde T; MacFarlane M; Madeo F; Malorni W; Manic G; Mantovani R; Marchi S; Marine J-C; Martin SJ; Martinou J-C; Mastroberardino PG; Medema JP; Mehlen P; Meier P; Melino G; Melino S; Miao EA; Moll UM; Munoz-Pinedo C; Murphy DJ; Niklison-Chirou MV; Novelli F; Nunez G; Oberst A; Ofengeim D; Opferman JT; Oren M; Pagano M; Panaretakis T; Pasparakis M; Penninger JM; Pentimalli F; Pereira DM; Pervaiz S; Peter ME; Pinton P; Porta G; Prehn JHM; Puthalakath H; Rabinovich GA; Rajalingam K; Ravichandran KS; Rehm M; Ricci J-E; Rizzuto R; Robinson N; Rodrigues CMP; Rotblat B; Rothlin CV; Rubinsztein DC; Rudel T; Rufini A; Ryan KM; Sarosiek KA; Sawa A; Sayan E; Schroder K; Scorrano L; Sesti F; Shao F; Shi Y; Sica GS; Silke J; Simon H-U; Sistigu A; Stephanou A; Stockwell BR; Strapazzon F; Strasser A; Sun L; Sun E; Sun Q; Szabadkai G; Tait SWG; Tang D; Tavernarakis N; Troy CM; Turk B; Urbano N; Vandenabeele P; Vanden Berghe T; Vander Heiden MG; Vanderluit JL; Verkhratsky A; Villunger A; von Karstedt S; Voss AK; Vousden KH; Vucic D; Vuri D; Wagner EF; Walczak H; Wallach D; Wang R; Wang Y; Weber A; Wood W; Yamazaki T; Yang H-T; Zakeri Z; Zawacka-Pankau JE; Zhang L; Zhang H; Zhivotovsky B; Zhou W; Piacentini M; Kroemer G; Galluzzi L
- Article: NPJ AGING AND MECHANISMS OF DISEASE. 2023;9(1):8Marin I; Serrano M; Pietrocola F
- Article: CANCER DISCOVERY. 2023;13(2):410-431Marin I; Boix O; Garcia-Garijo A; Sirois I; Caballe A; Zarzuela E; Ruano I; Attolini CS-O; Prats N; Lopez-Dominguez JA; Kovatcheva M; Garralda E; Munoz J; Caron E; Abad M; Gros A; Pietrocola F; Serrano M
- Review: CELL METABOLISM. 2023;35(1):12-35Lopez-Otin C; Pietrocola F; Roiz-Valle D; Galluzzi L; Kroemer G
- Article: ONCOIMMUNOLOGY. 2022;11(1):2146855Castoldi F; Kroemer G; Pietrocola F
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(41):e2207344119Motino O; Lambertucci F; Anagnostopoulos G; Li S; Nah J; Castoldi F; Senovilla L; Montegut L; Chen H; Durand S; Bourgin M; Aprahamian F; Nirmalathasan N; Alvarez-Valadez K; Sauvat A; Carbonnier V; Djavaheri-Mergny M; Pietrocola F; Sadoshima J; Maiuri MC; Martins I; Kroemer G
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Alla övriga publikationer
- Corrigendum: TRANSLATIONAL RESEARCH. 2025;276:38Arefin S; Mudrovcic N; Hobson S; Pietrocola F; Ebert T; Ward LJ; Witasp A; Hernandez L; Wennberg L; Lundgren T; Steinmetz-Spah J; Larsson K; Thorell A; Bruno S; Marengo M; Cantaluppi V; Stenvinkel P; Kublickiene K
- Preprint: BIORXIV. 2022Marín I; Boix O; García A; Sirois I; Caballe A; Zarzuela E; Ruano I; Attolini CS-O; Prats N; López-Domínguez JA; Kovatcheva M; Garralda E; Muñoz J; Caron E; Abad M; Gros A; Pietrocola F; Serrano M
- Book chapter: NON-CANONICAL AUTOPHAGY. 2021;p. 133-165Castoldi F; Pietrocola F
- Letter: JOURNAL OF HEPATOLOGY. 2020;73(4):970-972Extending the mode of action of triethylenetetramine (trientine): Autophagy besides copper chelationPietrocola F; Castoldi F; Zischka H; Kroemer G
- Conference publication: 2020;:4470Hernandez Gonzalez FI; Pietrocola F; Prats N; Meyer K; Lopez-Dominguez JA; Muñoz MI; Rovira M; Martinez D; Ramirez J; Agusti A; Faner R; Sellares J; Serrano M
- Editorial: CELL DEATH AND DIFFERENTIATION. 2020;27(6):2030-2032Kroemer G; Pietrocola F
- Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2020;201(Supplement_1):a7676Hernandez-Gonzalez F; Pietrocola F; Prats N; Meyer K; Lopez JA; Muñoz-Martin M; Agusti A; Faner MR; Torres JS; Serrano M
- Editorial: ONCOIMMUNOLOGY. 2019;8(10):e1616153Pietrocola F; Kroemer G
- Editorial: AUTOPHAGY. 2019;15(9):1662-1664Zimmermann A; Kainz K; Hofer SJ; Bauer MA; Schroeder S; Dengjel J; Pietrocola F; Kepp O; Ruckenstuhl C; Eisenberg T; Sigrist SJ; Madeo F; Carmona-Gutierrez D; Kroemer G
- Editorial: AUTOPHAGY. 2018;14(7):1162-1163Pietrocola F; Castoldi F; Maiuri MC; Kroemer G
- Editorial: ONCOTARGET. 2018;9(37):24574-24575Castoldi F; Pietrocola F; Maiuri MC; Kroemer G
- Editorial: AUTOPHAGY. 2017;13(4):767-769Eisenberg T; Abdellatif M; Zimmermann A; Schroeder S; Pendl T; Harger A; Stekovic S; Schipke J; Magnes C; Schmidt A; Ruckenstuhl C; Dammbrueck C; Gross AS; Herbst V; Carmona-Gutierrez D; Pietrocola F; Pieber TR; Sigrist SJ; Linke WA; Muehlfeld C; Sadoshima J; Dengjel J; Kiechl S; Kroemer G; Sedej S; Madeo F
- Editorial: CELL CYCLE. 2016;15(24):3327-3328Pietrocola F; Pol J; Kroemer G
- Editorial: AUTOPHAGY. 2016;12(10):1962-1964Pietrocola F; Pol J; Vacchelli E; Baracco EE; Levesque S; Castoldi F; Maiuri MC; Madeo F; Kroemer G
- Editorial: ONCOIMMUNOLOGY. 2016;5(2):e1078061Yang H; Yamazaki T; Pietrocola F; Zhou H; Zitvogel L; Ma Y; Kroemer G
- Editorial: CELL METABOLISM. 2015;22(5):757-758Galluzzi L; Pietrocola F; Kroemer G
- Editorial: AUTOPHAGY. 2014;10(11):1879-1882Marino G; Pietrocola F; Madeo F; Kroemer G
- Editorial: AUTOPHAGY. 2014;10(7):1335-1337Schroeder S; Pendl T; Zimmermann A; Eisenberg T; Carmona-Gutierrez D; Ruckenstuhl C; Marino G; Pietrocola F; Harger A; Magnes C; Sinner F; Pieber TR; Dengjel J; Sigrist SJ; Kroemer G; Madeo F
- Editorial: AUTOPHAGY. 2014;10(6):1143-1145Eisenberg T; Schroeder S; Buettner S; Carmona-Gutierrez D; Pendl T; Andryushkova A; Marino G; Pietrocola F; Harger A; Zimmermann A; Magnes C; Sinner F; Sedej S; Pieber TR; Dengjel J; Sigrist S; Kroemer G; Madeo F
- Editorial: AUTOPHAGY. 2014;10(5):930-932Marino G; Pietrocola F; Kong Y; Eisenberg T; Hill JA; Madeo F; Kroemer G
Forskningsbidrag
- Swedish Research Council1 januari 2024 - 31 december 2027The induction of senescence is a promising target in anticancer therapy, yet several obstacles limit its exploitation in the clinic. The overarching goal of this proposal is to uncover the mechanisms that enable transformed and non-transformed senescent cells to subvert T cell dependent anticancer immunity. The project is organized into two aims:AIM1: To harness immunological vulnerabilities of senescent tumor cells in cancer prophylaxis and therapy: We will exploit the induction of senescence in cancer cells ex vivo as tool to discover cancer neoantigens and develop cancer vaccination interventions amenable to clinical use. We will also use genetic barcoding technologies to specify the mechanisms that allow tumor senescent cells to escape T cell clearance.AIM2: To identify and target senescence-associated immune checkpoints in the tumor microenvironment. We will deploy single cell transcriptomics to map immunosuppressive senescent cell populations in the microenvironment of Non-Small Cell Lung Cancer (NSCLC) and identify Senescence Associated Immune Checkpoints (SAICs). We will test the efficacy of combination strategies based on induction of senescence in tumors and SAICs inhibition in mouse models of NSCLC.Overall, we expect that the results generated in this endeavor will be instrumental to devise novel interventions that combine the immunostimulatory potential of senescence with the inhibition of immunosuppressive features of the process for clinical use.
- Targeting polyamines metabolism to correct the detrimental effects of senescent cellsNovo Nordisk Foundation1 oktober 2022 - 30 september 2023
- Targeting polyamines metabolism to correct the detrimental effects of senescent cellsNovo Nordisk Foundation1 oktober 2021 - 30 september 2022
- Swedish Research Council1 januari 2020 - 31 december 2023