Ali Mirazimi

Ali Mirazimi

Adjunct Professor
Visiting address: Nobels väg 7, 17165 Solna
Postal address: H5 Laboratoriemedicin, H5 Klin Mikrobiologi Mirazimi, 141 52 Huddinge
Part of:

About me

  • Adjunct Professor, Karolinska Institute
    Head of Section, Swedish veterinary Institute
    Senior Expert Scintist, Public Health Agency of Sweden

Research

  • Viral Zoonosis, Virus-Host interaction, Diagnostic, Vaccine and Antivioral development

Articles

  • Article: ANTIVIRAL RESEARCH. 2025;244:106312
    Pasqual D; Artusi I; Paccagnella M; Sibille G; Mirandola M; Appelberg S; Priore MF; Zorzan M; Maffei ME; De Benedictis P; Del Vecchio C; Mirazimi A; Cozza G; Gribaudo G; Salata C
  • Article: BIOMEDICINE & PHARMACOTHERAPY. 2025;193:118858
    Ahlén G; Ambikan A; Mikaeloff F; Rezene S; Yan J; Nikouyan N; Revanna CB; Appelberg S; Mirazimi A; Sällberg M; Neogi U; Gupta S
  • Article: NPJ VACCINES. 2025;10(1):228
    Marchesin F; Bentley EM; Mutuku F; Jeza V; Ndenga B; Kempster S; Dowall SD; Almond N; Wright E; Banyard AC; Buczkowski H; Elaldi N; Mirazimi A; Hewson R; Rose NJ; Takeuchi Y; Mattiuzzo G
  • Article: BIOMEDICINE & PHARMACOTHERAPY. 2025;191:118447
    Tampere M; H Le T; Asp E; Kalman A; Kaimal JM; Njenda D; Bäckström A; Axelsson U; Xu H; Ouyang W; Axelsson H; Marabita F; Moussaud-Lamodière E; Sepulveda CO; Seashore-Ludlow B; Vernersson C; Mirazimi A; Lundberg E; Östling P; Stadler C
  • Article: JOURNAL OF GENERAL VIROLOGY. 2025;106(6):002077
    Kuhn JH; Adkins S; Alkhovsky Альховский Сергей Владимирович SV; An 安雯霞 W; Avšič-Županc T; Ayllón MA; Bačnik K; Bahl J; Balkema-Buschmann A; Ballinger MJ; Beer M; Bejerman N; Bergeron É; Biedenkopf N; Blair CD; Blasdell KR; Bradfute SB; Briese T; Brown K; Brown PA; Buchholz UJ; Buchmeier MJ; Bukreyev A; Burt F; Calisher CH; Calvelage S; Cao 曹孟籍 M; Casas I; Chabi-Jesus C; Chandran K; Charrel RN; Crane A; Cuypers LN; Bó ED; de la Torre JC; de Souza WM; de Swart RL; Debat HJ; Dheilly NM; Di Paola N; Di Serio F; Dietzgen RG; Digiaro M; Drexler JF; Duprex WP; Dürrwald R; Easton AJ; Elbeaino T; Ergünay K; Eshak MIY; Feng 冯国忠 G; Firth AE; Fooks AR; Formenty PBH; Freitas-Astúa J; Freuling CM; Gadd T; Gago-Zachert S; García ML; García-Sastre A; Garrison AR; Goldberg TL; Gonzalez J-PJ; Goüy de Bellocq J; Griffiths A; Groschup MH; Gryseels S; Gutiérrez-Aguirre I; Günther S; Hammond J; Hepojoki J; Horie 堀江真行 M; Hume AJ; Hyndman TH; Höper D; Jiāng 姜道宏 D; Junglen S; Klempa B; Klingström J; Kondō 近藤秀樹 H; Koonin EV; Krupovic M; Kubota 久保田健嗣 K; Kurath G; Kutnjak D; Laenen L; Lambert AJ; Lee B; Li 李呈宇 C; Lǐ 李建荣 J; Li 李俊敏 J-M; Lukashevich IS; Maes P; Marklewitz M; Marshall SH; Marzano S-YL; McCauley JW; Mehle N; Mirazimi A; Morikawa 守川俊幸 T; Mühlberger E; Müller T; Naidu R; Natsuaki 夏秋知英 T; Navarro B; Navarro JA; Neriya 煉谷裕太朗 Y; Netesov Нетёсов Сергей Викторович SV; Nicoloso VM; Neumann G; Nokireki T; Nowotny N; Nunes MRT; Ochoa-Corona FM; Palacios G; Pallás V; Papa Άννα Παπά A; Paraskevopoulou Σοφία Παρασκευοπούλου S; Parrish CR; Pauvolid-Corrêa A; Pecman A; Pérez DR; Pfaff F; Plemper RK; Postler TS; Radoshitzky SR; Ramos-González PL; Ravnikar M; Resende RO; Reuter G; Reyes CA; Rivarez MPS; Romanowski V; Rubbenstroth D; Rubino L; Runstadler JA; Ruiz-Padilla A; Sabanadzovic S; Salvato MS; Sasaya 笹谷孝英 I T; Schmaljohn CS; Schmidt-Posthaus H; Schwemmle M; Seljak G; Seuberlich T; Shi 施莽 M; Shimomoto 下元祥史 Y; Simmonds P; Sironi M; Smith DB; Smither S; Song 송진원 J-W; Spann KM; Spengler JR; Stenglein MD; Takada 高田礼人 A; Takemura C; Tammiranta N; Tesh RB; Thornburg NJ; Tischler ND; Tomitaka 冨髙保弘 Y; Tomonaga 朝長啓造 K; Tordo N; Turina M; Tzanetakis Ιωάννης Ε Τζανετάκης IE; Vaira AM; van den Hoogen B; Vanmechelen B; Vasilakis Νίκος Βασιλάκης N; Verbeek M; von Bargen S; Vučurović A; Wada 和田治郎 J; Wahl V; Walker PJ; Wang 王飞 F; Whitfield AE; Williams JV; Wolf YI; Yanagisawa 栁澤広宣 H; Yang 杨彩霞 C; Ye 叶恭银 G; Yu 于美春 MC; Zerbini FM; Zhang S; Økland AL; Hughes HR
  • Article: NATURE IMMUNOLOGY. 2025;26(6):934-946
    Kellner MJ; Monteil VM; Zelger P; Pei G; Jiao J; Onji M; Nayak K; Zilbauer M; Balkema-Buschmann A; Dorhoi A; Mirazimi A; Penninger JM
  • Journal article: BIOPHYSICAL JOURNAL. 2025;124(3):338a
    Zhu R; Stainer S; Reithofer M; Sikora M; Canena D; Seferovic H; Hain L; Laurent E; Monteil V; Mirazimi A; Oh YJ; Penninger JM; Hummer G; Klausberger M; Hinterdorfer P
  • Article: VIRUSES-BASEL. 2024;16(10):1539
    Andersson K; Azatyan A; Ekenberg M; Gucluler G; Sardon Puig L; Puumalainen M; Pramer T; Monteil VM; Mirazimi A
  • Article: VIRUS RESEARCH. 2024;346:199409
    Kempster S; Hassall M; Graham V; Kennedy E; Findlay-Wilson S; Salguero FJ; Bagci B; Elaldi N; Oz M; Tasseten T; Charlton FW; Barr JN; Fontana J; Duru C; Ezeajughi E; Matejtschuk P; Arnold U; Adedeji Y; Mirazimi A; Hewson R; Dowall S; Almond N
  • Article: JOURNAL OF VIROLOGY. 2024;98(6):e0052424-e00524
    Bagdonaite I; Abdurahman S; Mirandola M; Pasqual D; Frank M; Narimatsu Y; Joshi HJ; Vakhrushev SY; Salata C; Mirazimi A; Wandall HH
  • Article: NATURE MICROBIOLOGY. 2024;9(5):1499-1512
    Monteil VM; Wright SC; Dyczynski M; Kellner MJ; Appelberg S; Platzer SW; Ibrahim A; Kwon H; Pittarokoilis I; Mirandola M; Michlits G; Devignot S; Elder E; Abdurahman S; Bereczky S; Bagci B; Youhanna S; Aastrup T; Lauschke VM; Salata C; Elaldi N; Weber F; Monserrat N; Hawman DW; Feldmann H; Horn M; Penninger JM; Mirazimi A
  • Article: PLOS PATHOGENS. 2024;20(6):e1012262
    Flaxman A; Sebastian S; Appelberg S; Cha KM; Ulaszewska M; Purushotham J; Gilbride C; Sharpe H; Spencer AJ; Bibi S; Wright D; Schmidt I; Dowall S; Easterbrook L; Findlay-Wilson S; Gilbert S; Mirazimi A; Lambe T
  • Article: ANTIVIRAL RESEARCH. 2024;225:105844
    Welch SR; Garrison AR; Bente DA; Burt F; D'Addiego J; Devignot S; Dowall S; Fischer K; Hawman DW; Hewson R; Mirazimi A; Oestereich L; Vatansever Z; Spengler JR; Papa A
  • Article: JOURNAL OF GENERAL VIROLOGY. 2024;105(4):001974
    Kuhn JH; Alkhovsky SV; Avšič-Županc T; Bergeron É; Burt F; Ergünay K; Garrison AR; Marklewitz M; Mirazimi A; Papa A; Pawęska JT; Spengler JR; Palacios G
  • Article: MICROORGANISMS. 2024;12(3):443
    Husser C; Kwon H; Andersson K; Appelberg S; Montserrat N; Mirazimi A; Monteil VM
  • Journal article: MICROORGANISMS. 2024;12(3):443
    Husser C; Kwon H; Andersson K; Appelberg S; Montserrat N; Mirazimi A; Monteil VM
  • Article: MOLECULAR THERAPY. 2024;32(2):540-555
    Yan J; Bangalore CR; Nikouyan N; Appelberg S; Silva DN; Yao H; Pasetto A; Weber F; Weber S; Larsson O; Hoglund U; Bogdanovic G; Grabbe M; Aleman S; Szekely L; Szakos A; Tuvesson O; Gidlund E-K; Cadossi M; Salati S; Tegel H; Hober S; Frelin L; Mirazimi A; Ahlen G; Sallberg M
  • Article: NATURE COMMUNICATIONS. 2023;14(1):6785
    Monteil V; Kwon H; John L; Salata C; Jonsson G; Vorrink SU; Appelberg S; Youhanna S; Dyczynski M; Leopoldi A; Leeb N; Volz J; Hagelkruys A; Kellner MJ; Devignot S; Michlits G; Foong-Sobis M; Weber F; Lauschke VM; Horn M; Feldmann H; Elling U; Penninger JM; Mirazimi A
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(37):e2304722120
    Ambikan AT; Elaldi N; Akusjaervi SS; Bagci B; Pektas AN; Hewson R; Bagci G; Arasli M; Appelberg S; Mardinoglu A; Sood V; Vegvari A; Benfeitas R; Gupta S; Cetin I; Mirazimi A; Neogi U
  • Article: JOURNAL OF GENERAL VIROLOGY. 2023;104(8):001864
    Kuhn JH; Abe J; Adkins S; Alkhovsky SV; Avšič-Županc T; Ayllón MA; Bahl J; Balkema-Buschmann A; Ballinger MJ; Kumar Baranwal V; Beer M; Bejerman N; Bergeron É; Biedenkopf N; Blair CD; Blasdell KR; Blouin AG; Bradfute SB; Briese T; Brown PA; Buchholz UJ; Buchmeier MJ; Bukreyev A; Burt F; Büttner C; Calisher CH; Cao M; Casas I; Chandran K; Charrel RN; Kumar Chaturvedi K; Chooi KM; Crane A; Dal Bó E; Carlos de la Torre J; de Souza WM; de Swart RL; Debat H; Dheilly NM; Di Paola N; Di Serio F; Dietzgen RG; Digiaro M; Drexler JF; Duprex WP; Dürrwald R; Easton AJ; Elbeaino T; Ergünay K; Feng G; Firth AE; Fooks AR; Formenty PBH; Freitas-Astúa J; Gago-Zachert S; Laura García M; García-Sastre A; Garrison AR; Gaskin TR; Gong W; Gonzalez J-PJ; de Bellocq J; Griffiths A; Groschup MH; Günther I; Günther S; Hammond J; Hasegawa Y; Hayashi K; Hepojoki J; Higgins CM; Hongō S; Horie M; Hughes HR; Hume AJ; Hyndman TH; Ikeda K; Jiāng D; Jonson GB; Junglen S; Klempa B; Klingström J; Kondō H; Koonin EV; Krupovic M; Kubota K; Kurath G; Laenen L; Lambert AJ; Lǐ J; Li J-M; Liu R; Lukashevich IS; MacDiarmid RM; Maes P; Marklewitz M; Marshall SH; Marzano S-YL; McCauley JW; Mirazimi A; Mühlberger E; Nabeshima T; Naidu R; Natsuaki T; Navarro B; Navarro JA; Neriya Y; Netesov SV; Neumann G; Nowotny N; Nunes MRT; Ochoa-Corona FM; Okada T; Palacios G; Pallás V; Papa A; Paraskevopoulou S; Parrish CR; Pauvolid-Corrêa A; Pawęska JT; Pérez DR; Pfaff F; Plemper RK; Postler TS; Rabbidge LO; Radoshitzky SR; Ramos-González PL; Rehanek M; Resende RO; Reyes CA; Rodrigues TCS; Romanowski V; Rubbenstroth D; Rubino L; Runstadler JA; Sabanadzovic S; Sadiq S; Salvato MS; Sasaya T; Schwemmle M; Sharpe SR; Shi M; Shimomoto Y; Kavi Sidharthan V; Sironi M; Smither S; Song J-W; Spann KM; Spengler JR; Stenglein MD; Takada A; Takeyama S; Tatara A; Tesh RB; Thornburg NJ; Tian X; Tischler ND; Tomitaka Y; Tomonaga K; Tordo N; Tu C; Turina M; Tzanetakis IE; Maria Vaira A; van den Hoogen B; Vanmechelen B; Vasilakis N; Verbeek M; von Bargen S; Wada J; Wahl V; Walker PJ; Waltzek TB; Whitfield AE; Wolf YI; Xia H; Xylogianni E; Yanagisawa H; Yano K; Ye G; Yuan Z; Zerbini FM; Zhang G; Zhang S; Zhang Y-Z; Zhao L; Økland AL
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All other publications

Grants

  • Swedish Research Council
    1 January 2026 - 31 December 2027
    Purpose and aims: The overall purpose of the proposed network is to strengthen collaborations and networking in the area of virus and pandemics. The research area contains several research groups that are distributed all over Sweden and covers distinct disciplines. We aim to improve national and international collaborations and transfer of knowledge in the area. We are also aware that that virus-caused diseases is a focus area in pharmaceutical industry and hence we seek to increase collaborations between academy and industry. Finally, we aim to counteract fake news and vaccine resistance.Implementation: Supported by the Swedish Society for Virology (SSV), the applicants will initiate, coordinate, and/or support scientific meetings, PhD courses, the development of a national register for all pathogen-tested samples, and strategic use of BSL2-4 laboratories for pandemic preparedness. The co-applicants arrange digital meetings to plan activities and events, together with other organizations, in order to reach the goals set.Relevance: Virus-caused diseases, outbreaks, and pandemics constitute a huge burden on public health, health care and society. Coordinated efforts are needed to counteract these problems and threats. The described activities and collaborations increase scientific quality, and generation of new and better tools needed to understand and counteract virus-caused diseases, outbreaks, and pandemics.
  • Swedish Research Council
    1 December 2025 - 30 November 2028
    CCHFV is one of the most lethal tick-borne viruses, with high mortality and rapid geographic expansion driven by climate change. Despite its classification by the WHO as a priority pathogen, vaccine development is hampered by limited understanding of protective immune mechanisms, particularly T cell responses. This project aims to close that gap by uncovering how adaptive immunity,with focus to T cells , shapes protection during natural infection and vaccination. Leveraging one of the world’s largest longitudinal biobanks of CCHFV patients, in combination with cutting-edge animal models and advanced single-cell technologies, we will define the phenotype, function, and antigen-specificity of virus-specific T cells. Our dual focus is: (i) elucidating T cell dynamics in human infection, and (ii) mapping protective T cell responses in vaccine recipients. Preliminary data suggest T cells, rather than neutralizing antibodies, play a central role in controlling disease. Our integrated approach combines systemic and tissue-level immunoprofiling, functional assays, and peptide epitope mapping to identify immune correlates of protection. This cross-sectoral collaboration unites academia, hospitals, and public agencies to accelerate the development of next-generation vaccines that position immunity where it matters most—at the site of viral entry. The project will redefine vaccine strategies and enhance pandemic preparedness for this neglected but growing global threat.
  • Swedish Research Council
    1 January 2025 - 31 December 2028
    The National Doctoral Programme in Virus Infections and Pandemics (NDP-VIP) aims to advance the training and recruitment of PhD students and postdocs in virology and pandemic preparedness. This collaborative initiative involves nine leading Swedish universities and provides an interdisciplinary research environment integrating virology, epidemiology, public health, and social sciences for comprehensive training and understanding of infectious disease dynamics.NDP-VIP offers advanced courses taught by renowned researchers, covering viral pathogenesis, emerging viruses and zoonotic transmission, antiviral and vaccine development, socio-economic impacts of pandemics, and pandemic preparedness. Practical training in cutting-edge methodologies is a core component.The program fosters interdisciplinary cooperation through national virology network meetings, allowing PhD students and postdocs to present their research to the Swedish virology community. These activities aim to strengthen collaborations, facilitate knowledge exchange, and promote cross-disciplinary research and innovation.NDP-VIP’s outreach strategies, including partnerships with the Swedish Society for Virology and international collaborations, aim to attract top-tier candidates and create a vibrant network of young researchers. This initiative seeks to produce leading scientists and enhance Sweden´s capacity to respond to emerging infectious threats, ensuring national resilience and preparedness for future pandemics.
  • CCHFVaCIM
    1 January 2024 - 31 January 2028
  • COVID-19 Variant Supplement - Molecular and cellular therapies against COVID-19 using angiotensin-converting enzyme 2 (ACE2)
    Canadian Institutes of Health Research
    1 March 2021 - 28 February 2022
  • MADCOV2
    Innovative medicine initiative
    2 August 2020 - 30 April 2024
  • Vienna Science and Technology Fund
    1 May 2020 - 14 May 2023
  • Sex as a Biological Variable Supplement - Molecular and cellular therapies against COVID-19 using angiotensin-converting enzyme 2 (ACE2)
    Canadian Institutes of Health Research
    1 May 2020 - 30 April 2021
  • Molecular and cellular therapies against COVID-19 using angiotensin-converting enzyme 2 (ACE2)
    Canadian Institutes of Health Research
    1 February 2020 - 31 January 2022
  • Canadian Institutes of Health Research
    1 February 2020 - 31 January 2022
  • Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
    1 January 2017 - 31 December 2020
  • CCHFVaccine
    Horizon 2020
    1 January 2017 - 31 December 2024
  • Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
    1 January 2016 - 31 December 2018
  • Infect-ERA utlysning 2014: Second multilateral call for research Projects of Infect-ERA. ESCential, Haploid embryonic stem cell screen to identify host factors essential for highly pathogenic RNA vir
    Swedish Research Council
    1 December 2014 - 31 December 2016
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Employments

  • Adjunct Professor, Department of Laboratory Medicine, Karolinska Institutet, 2015-2027

Degrees and Education

  • Docent, Karolinska Institutet, 2006
  • Doctor Of Philosophy, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2000

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