Xiuming Liang

Article: NATURE COMMUNICATIONS. 2023;14(1):4734

Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles

Zheng W; Raedler J; Sork H; Niu Z; Roudi S; Bost JPP; Goergens A; Zhao Y; Mamand DRR; Liang X; Wiklander OPB; Lehto T; Gupta D; Nordin JZZ; EL Andaloussi S

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(12):e12290

Cell-specific targeting of extracellular vesicles though engineering the glycocalyx

Zheng W; He R; Liang X; Roudi S; Bost J; Pierre-Michael C; van Niel G; Andaloussi SEL

Article: CELL DEATH AND DIFFERENTIATION. 2022;29(11):2190-2202

Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer

Wang Y; Zheng L; Shang W; Yang Z; Li T; Liu F; Shao W; Lv L; Chai L; Qu L; Xu Q; Du J; Liang X; Zeng J; Jia J

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(7):e12248

Extracellular vesicles engineered to bind albumin demonstrate extended circulation time and lymph node accumulation in mouse models

Liang X; Niu Z; Galli V; Howe N; Zhao Y; Wiklander OPB; Zheng W; Wiklander RJ; Corso G; Davies C; Hean J; Kyriakopoulou E; Mamand DR; Amin R; Nordin JZ; Gupta D; Andaloussi SEL

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(6):e12238

Identification of storage conditions stabilizing extracellular vesicles preparations

Gorgens A; Corso G; Hagey DW; Wiklander RJ; Gustafsson MO; Felldin U; Lee Y; Bostancioglu RB; Sork H; Liang X; Zheng W; Mohammad DK; van DWSI; Vader P; Zickler AM; Mamand DR; Ma L; Holme MN; Stevens MM; Wiklander OPB; El Andaloussi S

Article: ADVANCED HEALTHCARE MATERIALS. 2022;11(5):e2101658

Growth Media Conditions Influence the Secretion Route and Release Levels of Engineered Extracellular Vesicles

Bost JP; Saher O; Hagey D; Mamand DR; Liang X; Zheng W; Corso G; Gustafsson O; Gorgens A; Smith CIE; Zain R; El Andaloussi S; Gupta D

Article: JCI INSIGHT. 2021;6(24):e146362

CPVL promotes glioma progression via STAT1 pathway inhibition through interactions with the BTK/p300 axis

Yang H; Liu X; Zhu X; Li X; Jiang L; Zhong M; Zhang M; Chen T; Ma M; Liang X; Lv K

Article: NATURE BIOMEDICAL ENGINEERING. 2021;5(9):1084-1098

Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles

Gupta D; Wiklander OPB; Goergens A; Conceicao M; Corso G; Liang X; Seow Y; Balusu S; Feldin U; Bostancioglu B; Jawad R; Mamand DR; Lee YXF; Hean J; Mager I; Roberts TC; Gustafsson M; Mohammad DK; Sork H; Backlund A; Lundin P; de Fougerolles A; Smith CIE; Wood MJA; Vandenbroucke RE; Nordin JZ; El-Andaloussi S

Article: JOURNAL OF PATHOLOGY. 2021;253(2):148-159

SETDB1 promotes gastric carcinogenesis and metastasis via upregulation of CCND1 and MMP9 expression

Shang W; Wang Y; Liang X; Li T; Shao W; Liu F; Cui X; Wang Y; Lv L; Chai L; Qu L; Zheng L; Jia J

Article: FRONTIERS IN ONCOLOGY. 2021;11:757497

Mechanisms of JARID1B Up-Regulation and Its Role in Helicobacter pylori-Induced Gastric Carcinogenesis.

Zheng L; Wu Y; Shen L; Liang X; Yang Z; Li S; Li T; Shang W; Shao W; Wang Y; Liu F; Ma L; Jia J

Article: MOLECULAR CANCER RESEARCH. 2021;19(1):74-85

Helicobacter pylori Induces a Novel NF-kB/LIN28A/let-7a/hTERT Axis to Promote Gastric Carcinogenesis

Shen L; Zeng J; Ma L; Li S; Chen C; Jia J; Liang X

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2020;9(1):1800222

Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging

Gupta D; Liang X; Pavlova S; Wiklander OPB; Corso G; Zhao Y; Saher O; Bost J; Zickler AM; Piffko A; Maire CL; Ricklefs FL; Gustafsson O; Llorente VC; Gustafsson MO; Bostancioglu RB; Mamand DR; Hagey DW; Goergens A; Nordin JZ; EL Andaloussi S

Article: EBIOMEDICINE. 2020;53:102672

Orphan nuclear receptor Nurr1 promotes Helicobacter pylori-associated gastric carcinogenesis by directly enhancing CDK4 expression

Shang W; Liang X; Li S; Li T; Zheng L; Shao W; Wang Y; Liu F; Ma L; Jia J

Article: EBIOMEDICINE. 2019;47:44-57

Identification of AUNIP as a candidate diagnostic and prognostic biomarker for oral squamous cell carcinoma

Yang Z; Liang X; Fu Y; Liu Y; Zheng L; Liu F; Li T; Yin X; Qiao X; Xu X

Article: CANCER MEDICINE. 2019;8(8):3965-3980

Helicobacter pylori-induced YAP1 nuclear translocation promotes gastric carcinogenesis by enhancing IL-1β expression.

Wu Y; Shen L; Liang X; Li S; Ma L; Zheng L; Li T; Yu H; Chan H; Chen C; Yu J; Jia J

Article: EBIOMEDICINE. 2019;39:301-314

H. pylori infection induced BMAL1 expression and rhythm disorder aggravate gastric inflammation

Li T; Shao W; Li S; Ma L; Zheng L; Shang W; Jia X; Sun P; Liang X; Jia J

Article: EBIOMEDICINE. 2018;38:69-78

CHAF1A interacts with TCF4 to promote gastric carcinogenesis via upregulation of c-MYC and CCND1 expression

Zheng L; Liang X; Li S; Li T; Shang W; Jia X; Shao W; Sun P; Chen C; Jia J

Article: ONCOGENE. 2018;37(7):884-896

MiR-22 sustains NLRP3 expression and attenuates H. pylori-induced gastric carcinogenesis.

Li S; Liang X; Ma L; Shen L; Li T; Zheng L; Sun A; Shang W; Chen C; Zhao W; Jia J

Article: FRONTIERS IN IMMUNOLOGY. 2018;9:1326

Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures

Wiklander OPB; Bostancioglu RB; Welsh JA; Zickler AM; Murke F; Corso G; Felldin U; Hagey DW; Evertsson B; Liang X-M; Gustafsson MO; Mohammad DK; Wiek C; Hanenberg H; Bremer M; Gupta D; Bjornstedt M; Giebel B; Nordin JZ; Jones JC; EL Andaloussi S; Goergens A

Article: EBIOMEDICINE. 2017;21:104-116

Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes

Liang X; Yuan X; Yu J; Wu Y; Li K; Sun C; Li S; Shen L; Kong F; Jia J; Bjorkholm M; Xu D

Article: FASEB JOURNAL. 2017;31(2):491-504

Human 15-lipoxygenase-1 is a regulator of dendritic-cell spreading and podosome formation

Han H; Liang X; Ekberg M; Kritikou JS; Brunnstrom A; Pelcman B; Matl M; Miao X; Andersson M; Yuan X; Schain F; Parvin S; Melin E; Sjoberg J; Xu D; Westerberg LS; Bjorkholm M; Claesson H-E

Article: AMERICAN JOURNAL OF CANCER RESEARCH. 2017;7(3):448-461

Histone demethylase PHF8 promotes progression and metastasis of gastric cancer.

Li S; Sun A; Liang X; Ma L; Shen L; Li T; Zheng L; Shang W; Zhao W; Jia J

Article: ONCOTARGET. 2016;7(10):11349-11363

Mutual amplification of HNF4α and IL-1R1 composes an inflammatory circuit in Helicobacter pylori associated gastric carcinogenesis.

Ma L; Zeng J; Guo Q; Liang X; Shen L; Li S; Sun Y; Li W; Liu S; Yu H; Chen C; Jia J

Article: ONCOTARGET. 2015;6(19):17661-17674

Histone demethylase RBP2 promotes malignant progression of gastric cancer through TGF-β1-(p-Smad3)-RBP2-E-cadherin-Smad3 feedback circuit.

Liang X; Zeng J; Wang L; Shen L; Ma X; Li S; Wu Y; Ma L; Ci X; Guo Q; Jia M; Shen H; Sun Y; Liu Z; Liu S; Li W; Yu H; Chen C; Jia J

Article: ONCOTARGET. 2014;5(14):5798-5807

Histone demethylase RBP2 induced by Helicobactor Pylori CagA participates in the malignant transformation of gastric epithelial cells.

Liang X; Zeng J; Wang L; Shen L; Li S; Ma L; Ci X; Yu J; Jia M; Sun Y; Liu Z; Liu S; Li W; Yu H; Chen C; Jia J

Article: MOLECULAR CANCER. 2014;13:81

Critical role of histone demethylase RBP2 in human gastric cancer angiogenesis.

Li L; Wang L; Song P; Geng X; Liang X; Zhou M; Wang Y; Chen C; Jia J; Zeng J

Article: PLOS ONE. 2014;9(8):e105306

Helicobacter pylori promotes epithelial-mesenchymal transition in gastric cancer by downregulating programmed cell death protein 4 (PDCD4).

Yu H; Zeng J; Liang X; Wang W; Zhou Y; Sun Y; Liu S; Li W; Chen C; Jia J

Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2013;114(12):2666-2672

MicroRNA-212 inhibits proliferation of gastric cancer by directly repressing retinoblastoma binding protein 2.

Jiping Z; Ming F; Lixiang W; Xiuming L; Yuqun S; Han Y; Zhifang L; Yundong S; Shili L; Chunyan C; Jihui J

Article: BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH. 2013;46(9):739-745

Histone demethylase retinoblastoma binding protein 2 regulates the expression of α-smooth muscle actin and vimentin in cirrhotic livers.

Wang Q; Wang LX; Zeng JP; Liu XJ; Liang XM; Zhou YB

Article: MOLECULAR CANCER RESEARCH. 2013;11(8):834-844

FoxM1 is overexpressed in Helicobacter pylori-induced gastric carcinogenesis and is negatively regulated by miR-370.

Feng Y; Wang L; Zeng J; Shen L; Liang X; Yu H; Liu S; Liu Z; Sun Y; Li W; Chen C; Jia J

Article: BRITISH JOURNAL OF CANCER. 2013;108(11):2272-2280

Telomerase reverse transcriptase inhibition stimulates cyclooxygenase 2 expression in cancer cells and synergizes with celecoxib to exert anti-cancer effects

Liu T; Liang X; Li B; Bjorkholm M; Jia J; Xu D

Article: PLOS ONE. 2013;8(7):e69784

Histone demethylase retinoblastoma binding protein 2 is overexpressed in hepatocellular carcinoma and negatively regulated by hsa-miR-212.

Liang X; Zeng J; Wang L; Fang M; Wang Q; Zhao M; Xu X; Liu Z; Li W; Liu S; Yu H; Jia J; Chen C

Article: EXPERIMENTAL BIOLOGY AND MEDICINE. 2012;237(4):435-441

Helicobacter pylori CagA induces ornithine decarboxylase upregulation via Src/MEK/ERK/c-Myc pathway: implication for progression of gastric diseases.

Xu X; Liu Z; Fang M; Yu H; Liang X; Li X; Liu X; Chen C; Jia J

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