Xiaowei Gong

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Articles

Article: MOLECULAR SYSTEMS BIOLOGY. 2023;19(6):e11490
Multisite assessment of reproducibility in high-content cell migration imaging data
Hu J; Serra-Picamal X; Bakker G-J; Van Troys M; Winograd-Katz S; Ege N; Gong X; Didan Y; Grosheva I; Polansky O; Bakkali K; Van Hamme E; van Erp M; Vullings M; Weiss F; Clucas J; Dowbaj AM; Sahai E; Ampe C; Geiger B; Friedl P; Bottai M; Stromblad S
Article: SCIENCE ADVANCES. 2022;8(12):eabl3667
Local temporal Rac1-GTP nadirs and peaks restrict cell protrusions and retractions
Hu J; Gong X; Stromblad S
Article: NATURE COMMUNICATIONS. 2019;10(1):3589
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer
Costa TDF; Zhuang T; Lorent J; Turco E; Olofsson H; Masia-Balague M; Zhao M; Rabieifar P; Robertson N; Kuiper R; Sjolund J; Spiess M; Hernandez-Varas P; Rabenhorst U; Roswall P; Ma R; Gong X; Hartman J; Pietras K; Adams PD; Defilippi P; Stromblad S
Article: NATURE CELL BIOLOGY. 2018;20(11):1290-1302
Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis.
Lock JG; Jones MC; Askari JA; Gong X; Oddone A; Olofsson H; Göransson S; Lakadamyali M; Humphries MJ; Strömblad S
Article: EMBO JOURNAL. 2018;37(17):e98994
KIF13A-regulated RhoB plasma membrane localization governs membrane blebbing and blebby amoeboid cell migration
Gong X; Didan Y; Lock JG; Stromblad S
Article: ELIFE. 2016;5:e11384
An analysis toolbox to explore mesenchymal migration heterogeneity reveals adaptive switching between distinct modes
Shafqat-Abbasi H; Kowalewski JM; Kiss A; Gong X; Hernandez-Varas P; Berge U; Jafari-Mamaghani M; Lock JG; Stromblad S
Article: AMERICAN JOURNAL OF CHINESE MEDICINE. 2016;44(5):1027-1041
Pinellia ternata Attenuates Mucus Secretion and Airway Inflammation after Inhaled Corticosteroid Withdrawal in COPD Rats
Du W; Su J; Ye D; Wang Y; Huang Q; Gong X
Article: INTEGRATIVE BIOLOGY (UNITED KINGDOM). 2015;7(10):1171-1185
Non-monotonic cellular responses to heterogeneity in talin protein expression-level
Kiss A; Gong X; Kowalewski JM; Shafqat-Abbasi H; Stromblad S; Lock JG
Article: PLOS ONE. 2015;10(8):e0135204
Disentangling Membrane Dynamics and Cell Migration; Differential Influences of F-actin and Cell-Matrix Adhesions
Kowalewski JM; Shafqat-Abbasi H; Jafari-Mamaghani M; Ganebo BE; Gong X; Stromblad S; Lock JG
Article: CELL METABOLISM. 2014;19(6):981-992
Early B Cell Factor 1 Regulates Adipocyte Morphology and Lipolysis in White Adipose Tissue
Gao H; Mejhert N; Fretz JA; Arner E; Lorente-Cebrian S; Ehrlund A; Dahlman-Wright K; Gong X; Stromblad S; Douagi I; Laurencikiene J; Dahlman I; Daub CO; Ryden M; Horowitz MC; Arner P
Article: PLOS ONE. 2014;9(2):e90593
Plasticity in the Macromolecular-Scale Causal Networks of Cell Migration
Lock JG; Mamaghani MJ; Shafqat-Abbasi H; Gong X; Tyrcha J; Stromblad S
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;425(2):357-362
Stress-induced interaction between p38 MAPK and HSP70
Gong X; Luo T; Deng P; Liu Z; Xiu J; Shi H; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO / JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2012;32(8):1148-1150
[A novel method for studying nuclear localization signal-mediated nuclear translocation].
Deng P; Gong X; Jiang Y
Article: PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. 2011;37(12):1265-1270
Progresses in The Studies on Kindlin Family Members
Xiong Y; Gong X-W; Jiang Y
Article: CANCER LETTERS. 2010;299(1):54-62
Kindlin-2 controls sensitivity of prostate cancer cells to cisplatin-induced cell death
Gong X; An Z; Wang Y; Guan L; Fang W; Stromblad S; Jiang Y; Zhang H
Article: FEBS LETTERS. 2010;584(23):4711-4716
UV-induced interaction between p38 MAPK and p53 serves as a molecular switch in determining cell fate
Gong X; Liu A; Ming X; Deng P; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO / JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2010;30(10):2310-2313
[Construction of pNTAP-MK2 eukaryotic expression plasmid and establishment of a cell line for its stable expression].
Wang D-A; Gong X-W; Liu A-H; Mei Z-Z; Wang D; Ming X-Y; Wang X; Wei J; Deng P; Jiang Y
Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2010;110(6):1420-1429
Mechanisms Regulating the Nuclear Translocation of p38 MAP Kinase
Gong X; Ming X; Deng P; Jiang Y
Journal article: FRONTIERS OF MEDICINE. 2010;4(1):46-53
Mitogen-activated protein kinase pathway inhibitors: inhibitors for diseases?
Wang X; Gong X-W; Li Y-H; Jiang Y
Journal article: FRONTIERS OF MEDICINE. 2009;3(4):379-383
Effect of PRAK gene knockout on the proliferation of mouse embryonic fibroblasts
Gong X; Liu A; Ming X; Wang X; Wang D; Deng P; Jiang Y
Article: THE FEBS JOURNAL. 2009;276(16):4598-4606
Advanced glycation end products and lipopolysaccharide synergistically stimulate proinflammatory cytokine/chemokine production in endothelial cells via activation of both mitogen-activated protein kinases and nuclear factor-κB
Liu J; Zhao S; Tang J; Li Z; Zhong T; Liu Y; Chen D; Zhao M; Li Y; Gong X; Deng P; Wang JH; Jiang Y
Article: GLYCOCONJUGATE JOURNAL. 2009;26(2):173-188
Lactosyl derivatives function in a rat model of severe burn shock by acting as antagonists against CD11b of integrin on leukocytes
Zhao Z; Li Q; Hu J; Li Z; Liu J; Liu A; Deng P; Zhang L; Gong X; Zhao K; Zhang S; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO / JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2008;28(10):1779-1781
[Construction of different mutants of HA-tagged human RAGE gene and their eukaryotic expression].
Cheng W-W; Li Y-S; Gong X-W; Zhao L-L; Wang J-G; Deng P; Jiang Y
Article: ZHONGGUO WEI ZHONG BING JI JIU YI XUE. 2008;20(9):527-529
[Effect of p38 mitogen-activated protein kinase gene knockout on cell proliferation of embryonic fibroblasts in mice].
Gong X-W; Wei J; Li Y-S; Cheng W-W; Deng P; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO / JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2008;28(5):671-674
[Construction and expression of different mutants of human p53 and their effects on arsenite-induced cell apoptosis].
Liu A-H; Gong X-W; Wei J; Ming X-Y; Wang D-A; Deng P; Luo S-Q; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO / JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2007;27(8):1132-1135
[Effect of p53 gene knockout on cell migration].
Gong X-W; Wei J; Li Y-S; Cheng W-W; Wang X; Deng P; Jiang Y
Journal article: FRONTIERS OF MEDICINE IN CHINA. 2007;1(3):248-252
Involvement of p38 mitogen-activated protein kinase in the regulation of platelet-derived growth factor -induced cell migration.
Gong X; Wei J; Li Y; Cheng W; Deng P; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO / JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2007;27(7):983-986
[Construction and expression of the fusion vector for HA-tagged human RAGE gene].
Li Y-S; Gong X-W; Cheng W-W; Wei J; Jiang Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2005;25(6):619-622
[Effect of Liangge San on lipopolysaccharide-induced nuclear factor kappa B activation in cultured mouse macrophages].
Jiang A-D; Yu L-Z; Gong X-W; Deng P; Ma X-D
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2005;25(3):285-288
[Construction and expression of green fluorescent protein fusion vector of p38 regulated/activated protein kinase].
Peng Y; Gong X-W; Deng P; Qin Q-H; Jiang Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2004;24(6):628-635
[Construction and expression of the fusion vector of His-tagged human ARPC2 gene].
Gong X-W; Peng Y; Liu J-H; Li Z-J; Deng P; Qin Q-H; Jiang Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2004;24(2):139-143
Killing effect of suicide gene system under control by KDR promotor on human umbilical vein endothelial cells.
Huang Z-H; Yang W-Y; Gong X-W; Qian Y; Che X-Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2003;23(11):1131-1133
[Screening and identification of proteins interacting with p38 MAP kinase via T7 phage-display screening system].
Li Z-J; Liu J-H; Gong X-W; Qin Q-H; Huang H; Deng P; Wang J-Z; Zhao S-C; Sun X-G; Liu Y-W; Zhao K-S; Jiang Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2003;23(3):206-209
Regulation of inducible nitricoxide synthase gene transcription by p38 mitogen-activated protein kinase in human embryonic kidney 293 cells.
Guo A-H; Gong X-W; Kan W-H; Qin Q-H; Deng P; Wang J-Z; Jiang Y
Article: ZHONGGUO WEI ZHONG BING JI JIU YI XUE. 2003;15(3):163-166
[Construction of vector of his-tagged cytoplasmic fragment of human toll like receptor 4 and its expression in E.coli].
Liu J-H; Sun X-G; Li Z-J; Qin Q-H; Gong X-W; Deng P; Liu Y-W; Wang J-Z; Zhao K-S; Jiang Y
Article: PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. 2003;30(4):509-513
Mechanisms of the subcellular localization and stimuli-induced translocation of MAP kinases
Gong XW; Jiang Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2002;22(2):171-173
[Construction and expression of red fluorescent protein fusion vector incorporating p38 mitogen-activated protein kinase].
Gong X-W; Qin Q-H; Wang J-Z; Jiang Y
Article: PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. 2001;28(3):299-303
The role of TLR4 in response to LPS in mammals
Gong XW; Jiang Y
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All other publications

Preprint: BIORXIV. 2022
Multi-site assessment of reproducibility in high-content live cell imaging data
Hu J; Serra-Picamal X; Bakker G-J; Van Troys M; Winograd-katz S; Ege N; Gong X; Didan Y; Grosheva I; Polansky O; Bakkali K; Van Hamme E; Van Erp M; Vullings M; Weiss F; Clucas J; Dowbaj AM; Sahai E; Ampe C; Geiger B; Friedl P; Bottai M; Strömblad S
Preprint: BIORXIV. 2021
Local temporal Rac1-GTP nadirs and peaks restrict cell protrusions and retractions
Hu J; Gong X; Strömblad S
Preprint: BIORXIV. 2017
Reticular adhesions: A new class of adhesion complex that mediates cell-matrix attachment during mitosis
Lock J; Jones M; Askari J; Gong X; Oddone A; Olofsson H; Göransson S; Lakadamyali M; Humphries M; Strömblad S
Review: PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. 2007;34(7):695-701
Progresses in mitogen-activated protein kinase-activated protein kinases
Gong X-W; Jiang Y
Review: SHENG LI KE XUE JIN ZHAN [PROGRESS IN PHYSIOLOGY]. 2004;35(4):306-310
[Structure, function and modulation of actin-related protein 2/3 complex].
Gong X-W; Jiang Y

Grants

The role of Kindlin-2 and Prdx4 in inflammation-induced tumors and its mechanism
National Natural Science Foundation of China
1 January 2012 - 31 December 2015
Multiparametric analyses of the effects of targeted gene knockdown on cell motility and CMAC organisation
Karolinska Institutet Research Foundation
1 January 2012 - 31 December 2012
Cell stress-induced nuclear translocation of p38 MAPK molecular mechanism
National Natural Science Foundation of China
1 January 2008 - 31 December 2010
Identification of the interaction domains between ARPC2 and PRAK.
Medical Science and Technology Foundation of Guangdong Province, China
1 January 2006 - 31 December 2007

Employments

Researcher, Department of Medicine, Huddinge, Karolinska Institutet, 2024-
Associate professor, Pathophysiology, Southern Medical University, 2008-2015
Lecturer, Pathophysiology, Southern Medical University, 2004-2007
Lecturer, Pathophysiology, The First Military Medical University, 2004-2004
Teaching assistant, Pathophysiology, The First Military Medical University, 2001-2004

Degrees and Education

PhD, MD, The First Military Medical University, 2004
Master degree in Pathophysiology, The First Military Medical University, 2001
Bachelor degree in Clinical Medicine, Clinical Medicine, The First Military Medical University, 1998

Visiting research fellowships

PostDoc, Karolinska Institute, 2008-2010

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