Weng-Onn Lui
Professor
E-mail: weng-onn.lui@ki.se
Visiting address: J6:20 BioClinicum, Akademiska stråket 1, 17164 SOLNA
Postal address: K7 Onkologi-Patologi, K7 Forskning Larsson Catharina Lui, 171 77 Stockholm
About me
Current position
Professor in Experimental Oncology, Since July 2024
Previous appointments
Associate professor (molecular genetics), Department of Oncology-Pathology, Karolinska Institutet, Jan 2014 - June 2024
Research fellow (VR Rådsforskare), Department of Oncology-Pathology, Karolinska Institutet, September 2010 – August 2016
researchAssistant professor, Department of Molecular Medicine and Surgery, Karolinska Institutet, July 2008 - 2014
Postdoctoral fellow, Stanford University School of Medicine, USA (Advisor:
Andrew Fire), Sep 2004-June 2008
Postdoctoral fellow, Department of Molecular Medicine (Advisor: Catharina
Larsson), Nov 2002-Aug 2004Educations
1999–2002, Karolinska Institutet, Sweden, PhD (Medical Genetics)
1992-1996, Tunku Abdul Rahman College, Malaysia, BSc (Applied Science)
DistinctionsAACR-Ortho Biotech Scholar-in-Training Award (2003)
AACR-AFLAC Scholar-in-training award (2005, 2006)
Translational Research Award, Stanford Comprehensive Cancer Center (2007)
Swedish Research Council Junior Fellowship (2008, 4 years)
Swedish Research Council Senior Fellowship (2010, 6 years)
Research
- My primary research area is on small RNA biology. Our research activity is
mainly focusing on studying the role of small RNAs in cancer development and
drug resistance.
http://ki.se/ki/jsp/polopoly.jsp?d=44413&;a=156545&l=en
A major effort of our previous work had focused on the identification of
novel small RNAs (particularly miRNAs) and the documentation of their
expression patterns in several tissue types. We also evaluated the potential
use of miRNA expression profiles in tumor classification and prognostication.
Our current projects focus primarily on the functional roles of small RNAs
along with their regulatory components in clinically relevant experimental
systems.
Selected publications
- Review: DRUG RESISTANCE UPDATES. 2026;85:101355Tufail M; Gong K; Ijaz B; Patel H; Lui W-O; Wang X; Li J
- Article: ONCOGENE. 2025;44(47):4615-4625Lei KC; Srinivas N; Chandra M; Serobyan V; Ugurel S; Hoffmann D; Kervarrec T; Lui W-O; Becker JC
- Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2025;13(9):e012224Srinivas N; Spassova I; Lei KC; Gao J; Pino MJ; Giglio G; Kitanovski S; Dalkoohi M; Livingstone E; Leiter U; Mohr P; Gambichler T; Stoffels I; Ugurel S; Cheung PF-Y; Engblom C; Lui W-O; Becker JC
- Article: NATURE COMMUNICATIONS. 2025;16(1):6610Gao X; Zhang J; Zhang H; Liu X; Zeng B; Wang H; Zhang H; Lui W-O; Hui X; Miao H; Li J
- Article: AUTOPHAGY. 2025;21(7):1523-1543Shi H; Yang Y; Gao J; Kumar S; Xie H; Chen Z; Lyu J; Sihto H; Koljonen V; Vega-Rubin-de-Celis S; Vukojevic V; Farnebo F; Bjornhagen V; Hoog A; Juhlin CC; Lee L; Wickstroem M; Becker JC; Johnsen JI; Larsson C; Lui W-O
- Other: LANCET ONCOLOGY. 2025;26(8):994-995Karagas MR; Kaldor J; Michaelis M; Muchengeti MM; Alfaiate D; Argirion I; Chen X; Cunha C; Hantz S; Koljonen V; Laude HC; Lui W-O; Nevels MM; O'Brien TR; Scheurer ME; Touze A; Wiemels JL; Benbrahim-Tallaa L; de Conti A; Facchin C; Madia F; Pasqual E; Wedekind R; Aguilera-Buenosvinos I; Clifford G; Deng X; Dongoran RA; Ezzemni S; Huang Y; Suonio E; Zhai Y; Mattock H; Schubauer-Berigan MK; Kunzmann A
- Article: DEVELOPMENTAL CELL. 2023;58(6):450-460.e6Subramanian E; Elewa A; Brito G; Kumar A; Segerstolpe A; Karampelias C; Bjorklund A; Sandberg R; Echeverri K; Lui W-O; Andersson O; Simon A
- Article: ISCIENCE. 2021;24(11):103264Gao J; Shi H; Juhlin CC; Larsson C; Lui W-O
- Article: INTERNATIONAL JOURNAL OF CANCER. 2020;146(6):1652-1666Kumar S; Xie H; Shi H; Gao J; Juhlin CC; Bjornhagen V; Hoog A; Lee L; Larsson C; Lui W-O
- Article: BLOOD CANCER JOURNAL. 2013;3(10):e152Caramuta S; Lee L; Ozata DM; Akcakaya P; Georgii-Hemming P; Xie H; Amini R-M; Lawrie CH; Enblad G; Larsson C; Berglund M; Lui W-O
- Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2013;20(4):440-446Johnsson P; Ackley A; Vidarsdottir L; Lui W-O; Corcoran M; Grander D; Morris KV
- Article: CANCER RESEARCH. 2008;68(17):7156-7164Lui W-O; Zeng L; Rehmann V; Deshpande S; Tretiakova M; Kaplan EL; Leibiger I; Leibiger B; Enberg U; Hoog A; Larsson C; Kroll TG
- Article: CANCER RESEARCH. 2007;67(13):6031-6043Lui W-O; Pourmand N; Patterson BK; Fire A
- Article: CANCER CELL. 2003;4(5):405-413Chen JD; Lui WO; Vos MD; Clark GJ; Takahashi M; Schoumans J; Khoo SK; Petillo D; Lavery T; Sugimura J; Astuti D; Zhang C; Kagawa S; Maher ER; Larsson C; Alberts AS; Kanayama HO; Teh BT
- Article: NATURE BIOTECHNOLOGY. 2000;18(9):1001-1005Lindblad-Toh K; Tanenbaum DM; Daly MJ; Winchester E; Lui WO; Villapakkam A; Stanton SE; Larsson C; Hudson TJ; Johnson BE; Lander ES; Meyerson M
Articles
- Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2026;:S0022-202X(26)02812-5Wang X; Sihto H; Yang Y; Larsson C; Shi H; Lui W-O
- Article: MOLECULAR CARCINOGENESIS. 2025;64(11):1899-1912Zheng B; Li M; Gao Z; Yang Y; Guo K; Gao H; Zhao Y; Lui W-O; Xie H
- Article: JID INNOVATIONS. 2025;5(3):100355Yang Y; Gao J; Shi H; Sihto H; Kilpinen S; Vilcot F; Janska L; Jeschonneck J; Cvetanovic T; Hoog A; Siarov J; Paoli J; Juhlin CC; Villabona L; Larsson C; Lui W-O
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2025;110(3):693-705Xu Y; Gao J; Wang N; Zedenius J; Nilsson I-L; Lui W-O; Xu D; Juhlin CC; Larsson C; Mu N
- Article: CELLS. 2023;12(13):1682Subramani A; Cui W; Zhang Y; Friman T; Zhao Z; Huang W; Fonseca P; Lui W-O; Narayanan V; Bobrowska J; Lekka M; Yan J; Conway DEE; Holmgren L
- Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2022;61(5):140Scicluna P; Caramuta S; Kjellin H; Xu C; Froebom R; Akhtar M; Gao J; Shi H; Kjellman M; Almgren M; Hoog A; Zedenius J; Ekstroem TJ; Braenstroem R; Lui W-O; Larsson C
- Article: BIOMEDICINE & PHARMACOTHERAPY. 2022;149:112796Yuan H; Wu Y; Wang J; Qin X; Huang Y; Yan L; Fana Y; Zedenius J; Juhlin CC; Larsson C; Lui W-O; Xu D
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(7):3702Rasheed K; Moens U; Policastro B; Johnsen JI; Koljonen V; Sihto H; Lui W-O; Sveinbjornsson B
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(19):10600Huang W-K; Shi H; Akcakaya P; Zeljic K; Gangaev A; Caramuta S; Yeh C-N; Branstrom R; Larsson C; Lui W-O
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021;557:14-19Frobom R; Berglund E; Aspinwall CA; Lui W-O; Nilsson I-L; Larsson C; Branstrom R
- Article: CANCERS. 2021;13(2):E265-265Andtback HB; Bjornhagen-Safwenberg V; Shi H; Lui W-O; Masucci GV; Villabona L
- Article: CELLS. 2020;9(6):E1333-1333Huang W-K; Gao J; Chen Z; Shi H; Yuan J; Cui HL; Yeh C-N; Branstrom R; Larsson C; Li S; Lui W-O
- Article: ENDOCRINE-RELATED CANCER. 2020;27(5):295-308Paulsson JO; Wang N; Gao J; Stenman A; Zedenius J; Mu N; Lui W-O; Larsson C; Juhlin CC
- Article: ANTICANCER RESEARCH. 2019;39(7):3433-3442Frobom R; Sellberg F; Xu C; Zhao A; Larsson C; Lui W-O; Nilsson I-L; Berglund E; Branstrom R
- Article: CANCERS. 2018;10(11):E443-443Kumar S; Xie H; Scicluna P; Lee L; Bjornhagen V; Hoog A; Larsson C; Lui W-O
- Article: EXPERIMENTAL CELL RESEARCH. 2018;371(1):287-296Huang W-K; Akcakaya P; Gangaev A; Lee L; Zeljic K; Hajeri P; Berglund E; Ghaderi M; Ahlen J; Branstrom R; Larsson C; Lui W-O
- Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2018;16(4):791-801Miao X; Rahman MF-U; Jiang L; Min Y; Tan S; Xie H; Lee L; Wang M; Malmstrom RE; Lui W-O; Li N
- Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2018;52(1):55-66Chang RK; Li X; Mu N; Hrydziuszko O; Garcia-Majano B; Larson C; Lui W-O
- Article: CELL DEATH & DISEASE. 2017;8(5):e2759Ozata DM; Li X; Lee L; Liu J; Warsito D; Hajeri P; Hultman I; Fotouhi O; Marklund S; Ahrlund-Richter L; Juhlin CC; Larsson C; Lui W-O
- Article: JOURNAL OF GENERAL VIROLOGY. 2017;98(5):1058-1072Mohammad A-A; Costa H; Landazuri N; Lui W-O; Hultenby K; Rahbar A; Yaiw K-C; Soderberg-Naucler C
- Show more
All other publications
- Corrigendum: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2025;320(Pt 1):146595Li J; Lu J; Liu G; Li J; Chen J; Wang X; Lui W-O; Lu G
- Corrigendum: ONCOGENE. 2023;42(9):709Bersani C; Xu L-D; Vilborg A; Lui W-O; Wiman KG
- Editorial: CANCERS. 2021;13(9):2259Koljonen V; Lui W-O; Becker JC
- Letter: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2012;10(10):2202-2205Huang Z; Rahman MF-U; Jiang L; Xie H; Hu H; Lui W-O; Li N
- Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):224Ozata D; Caramuta S; Akcakaya P; Xie HONG; Backdahl M; Larsson C; Lui W
- Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):187Xie H; Caramuta S; Larsson C; Lui WO
- Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):185Caramuta S; Berglund M; Ozata D; Akcakaya P; Georgii-Hemming P; Xie H; Enblad G; Larsson C; Lui WO
- Doctoral thesis: 2002Lui W-O
- Letter: CANCER GENETICS. 2002;136(2):153-154Lau LC; Lim P; Lee LH; Hwang W; Lui WO; Chong YY
Employments
- Professor, Experimental Oncology, Department of Oncology-Pathology, Karolinska Institutet, 2024-
- Senior Lecturer, Department of Oncology-Pathology, Karolinska Institutet, 2016-2024
Degrees and Education
- Docent, Karolinska Institutet, 2014
- Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2002
Supervision
Supervision to doctoral degree
- Zana Brilej, 2025-
- Yaije Yang, 2025
- Libuse Janská, 2023-
- Hannah Björn Andtback, 2022-
- Jiwei Gao, 2022
- Xiaohao Wang, 2021-
- Hao Shi, 2020
- Wen-Kuan Huang, 2020
- Patrick Scicluna, Differential microRNA and Metabolic Expressions in Neuroendocrine and Cervical Carcinomas, 2020
- Satendra Kumar, 2019