Weng-Onn Lui

About me
Publications
CV
Public outreach and news

About me

Current position
Professor in Experimental Oncology, Since July 2024
Previous appointments
Associate professor (molecular genetics), Department of Oncology-Pathology, Karolinska Institutet, Jan 2014 - June 2024
Research fellow (VR Rådsforskare), Department of Oncology-Pathology, Karolinska Institutet, September 2010 – August 2016
research
Assistant professor, Department of Molecular Medicine and Surgery, Karolinska Institutet, July 2008 - 2014
Postdoctoral fellow, Stanford University School of Medicine, USA (Advisor:
Andrew Fire), Sep 2004-June 2008
Postdoctoral fellow, Department of Molecular Medicine (Advisor: Catharina
Larsson), Nov 2002-Aug 2004
Educations
1999–2002, Karolinska Institutet, Sweden, PhD (Medical Genetics)
1992-1996, Tunku Abdul Rahman College, Malaysia, BSc (Applied Science)

Distinctions
AACR-Ortho Biotech Scholar-in-Training Award (2003)
AACR-AFLAC Scholar-in-training award (2005, 2006)
Translational Research Award, Stanford Comprehensive Cancer Center (2007)
Swedish Research Council Junior Fellowship (2008, 4 years)
Swedish Research Council Senior Fellowship (2010, 6 years)

Research

My primary research area is on small RNA biology. Our research activity is
mainly focusing on studying the role of small RNAs in cancer development and
drug resistance.
http://ki.se/ki/jsp/polopoly.jsp?d=44413&
a=156545&
l=en
A major effort of our previous work had focused on the identification of
novel small RNAs (particularly miRNAs) and the documentation of their
expression patterns in several tissue types. We also evaluated the potential
use of miRNA expression profiles in tumor classification and prognostication.
Our current projects focus primarily on the functional roles of small RNAs
along with their regulatory components in clinically relevant experimental
systems.

Articles

Article: CELLS. 2023;12(13):1682
Modulation of E-Cadherin Function through the AmotL2 Isoforms Promotes Ameboid Cell Invasion
Subramani A; Cui W; Zhang Y; Friman T; Zhao Z; Huang W; Fonseca P; Lui W-O; Narayanan V; Bobrowska J; Lekka M; Yan J; Conway DEE; Holmgren L
Article: DEVELOPMENTAL CELL. 2023;58(6):450-460.e6
A small noncoding RNA links ribosome recovery and translation control to dedifferentiation during salamander limb regeneration
Subramanian E; Elewa A; Brito G; Kumar A; Segerstolpe A; Karampelias C; Bjorklund A; Sandberg R; Echeverri K; Lui W-O; Andersson O; Simon A
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2022;61(5):140
Altered expression of the IGF2-H19 locus and mitochondrial respiratory complexes in adrenocortical carcinoma
Scicluna P; Caramuta S; Kjellin H; Xu C; Froebom R; Akhtar M; Gao J; Shi H; Kjellman M; Almgren M; Hoog A; Zedenius J; Ekstroem TJ; Braenstroem R; Lui W-O; Larsson C
Article: BIOMEDICINE & PHARMACOTHERAPY. 2022;149:112796
Synergistic effects of telomerase reverse transcriptase and regulator of telomere elongation helicase 1 on aggressiveness and outcomes in adrenocortical carcinoma
Yuan H; Wu Y; Wang J; Qin X; Huang Y; Yan L; Fana Y; Zedenius J; Juhlin CC; Larsson C; Lui W-O; Xu D
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(7):3702
The Merkel Cell Polyomavirus T-Antigens and IL-33/ST2-IL1RAcP Axis: Possible Role in Merkel Cell Carcinoma
Rasheed K; Moens U; Policastro B; Johnsen JI; Koljonen V; Sihto H; Lui W-O; Sveinbjornsson B
Article: ISCIENCE. 2021;24(11):103264
Merkel cell polyomavirus T-antigens regulate DICER1 mRNA stability and translation through HSC70
Gao J; Shi H; Juhlin CC; Larsson C; Lui W-O
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(19):10600
Imatinib Regulates miR-483-3p and Mitochondrial Respiratory Complexes in Gastrointestinal Stromal Tumors
Huang W-K; Shi H; Akcakaya P; Zeljic K; Gangaev A; Caramuta S; Yeh C-N; Branstrom R; Larsson C; Lui W-O
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021;557:14-19
Direct interaction of the ATP-sensitive K⁺ channel by the tyrosine kinase inhibitors imatinib, sunitinib and nilotinib
Frobom R; Berglund E; Aspinwall CA; Lui W-O; Nilsson I-L; Larsson C; Branstrom R
Article: CANCERS. 2021;13(2):E265-265
Sex Differences in Overall Survival and the Effect of Radiotherapy in Merkel Cell Carcinoma-A Retrospective Analysis of A Swedish Cohort
Andtback HB; Bjornhagen-Safwenberg V; Shi H; Lui W-O; Masucci GV; Villabona L
Article: CELLS. 2020;9(6):E1333-1333
Heterogeneity of Metabolic Vulnerability in Imatinib-Resistant Gastrointestinal Stromal Tumor
Huang W-K; Gao J; Chen Z; Shi H; Yuan J; Cui HL; Yeh C-N; Branstrom R; Larsson C; Li S; Lui W-O
Article: ENDOCRINE-RELATED CANCER. 2020;27(5):295-308
GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours
Paulsson JO; Wang N; Gao J; Stenman A; Zedenius J; Mu N; Lui W-O; Larsson C; Juhlin CC
Article: INTERNATIONAL JOURNAL OF CANCER. 2020;146(6):1652-1666
Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes
Kumar S; Xie H; Shi H; Gao J; Juhlin CC; Bjornhagen V; Hoog A; Lee L; Larsson C; Lui W-O
Article: ANTICANCER RESEARCH. 2019;39(7):3433-3442
Biochemical Inhibition of DOG1/TMEM16A Achieves Antitumoral Effects in Human Gastrointestinal Stromal Tumor Cells In Vitro
Frobom R; Sellberg F; Xu C; Zhao A; Larsson C; Lui W-O; Nilsson I-L; Berglund E; Branstrom R
Article: CANCERS. 2018;10(11):E443-443
MiR-375 Regulation of LDHB Plays Distinct Roles in Polyomavirus-Positive and -Negative Merkel Cell Carcinoma
Kumar S; Xie H; Scicluna P; Lee L; Bjornhagen V; Hoog A; Larsson C; Lui W-O
Article: EXPERIMENTAL CELL RESEARCH. 2018;371(1):287-296
miR-125a-5p regulation increases phosphorylation of FAK that contributes to imatinib resistance in gastrointestinal stromal tumors
Huang W-K; Akcakaya P; Gangaev A; Lee L; Zeljic K; Hajeri P; Berglund E; Ghaderi M; Ahlen J; Branstrom R; Larsson C; Lui W-O
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2018;16(4):791-801
Thrombin-reduced miR-27b attenuates platelet angiogenic activities in vitro via enhancing platelet synthesis of anti-angiogenic thrombospondin-1
Miao X; Rahman MF-U; Jiang L; Min Y; Tan S; Xie H; Lee L; Wang M; Malmstrom RE; Lui W-O; Li N
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2018;52(1):55-66
MicroRNA expression profiles in non-epithelial ovarian tumors
Chang RK; Li X; Mu N; Hrydziuszko O; Garcia-Majano B; Larson C; Lui W-O
Article: CELL DEATH & DISEASE. 2017;8(5):e2759
Loss of miR-514a-3p regulation of PEG3 activates the NF-kappa B pathway in human testicular germ cell tumors
Ozata DM; Li X; Lee L; Liu J; Warsito D; Hajeri P; Hultman I; Fotouhi O; Marklund S; Ahrlund-Richter L; Juhlin CC; Larsson C; Lui W-O
Article: JOURNAL OF GENERAL VIROLOGY. 2017;98(5):1058-1072
Human cytomegalovirus microRNAs are carried by virions and dense bodies and are delivered to target cells
Mohammad A-A; Costa H; Landazuri N; Lui W-O; Hultenby K; Rahbar A; Yaiw K-C; Soderberg-Naucler C
Article: ONCOLOGY LETTERS. 2017;13(5):3586-3598
Evaluation of microRNA-205 expression as a potential triage marker for patients with low-grade squamous intraepithelial lesions
Xie H; Norman I; Hjerpe A; Vladic T; Larsson C; Lui W-O; Ostensson E; Andersson S
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2017;50(2):356-364
miR-223-3p regulates cell growth and apoptosis via FBXW7 suggesting an oncogenic role in human testicular germ cell tumors
Liu J; Shi H; Li X; Chen G; Larsson C; Lui W-O
Article: ONCOTARGET. 2016;7(2):1895-1911
Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis
Bersani C; Huss M; Giacomello S; Xu L-D; Bianchi J; Eriksson S; Jerhammar F; Alexeyenko A; Vilborg A; Lundeberg J; Lui W-O; Wiman KG
Article: PLOS ONE. 2016;11(4):e0152032
Tissue and Serum miRNA Profile in Locally Advanced Breast Cancer (LABC) in Response to Neo-Adjuvant Chemotherapy (NAC) Treatment
Al-Khanbashi M; Caramuta S; Alajmi AM; Al-Haddabi I; Al-Riyami M; Lui W-O; Al-Moundhri MS
Article: EXPERIMENTAL CELL RESEARCH. 2015;336(1):158-170
Secretome protein signature of human gastrointestinal stromal tumor cells
Berglund E; Dare E; Branca RMM; Akcakaya P; Frobom R; Berggren P-O; Lui W-O; Larsson C; Zedenius J; Orre L; Lehtio J; Kim J; Branstrom R
Article: INTERNATIONAL JOURNAL OF CANCER. 2015;136(5):E230-E241
Novel functions and targets of miR-944 in human cervical cancer cells
Xie H; Lee L; Scicluna P; Kavak E; Larsson C; Sandberg R; Lui W-O
Article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2015;889:51-70
MicroRNAs and Gastrointestinal Stromal Tumor.
Akçakaya P; Lui W-O
Article: BRITISH JOURNAL OF CANCER. 2014;111(11):2091-2102
microRNA expression signatures of gastrointestinal stromal tumours: associations with imatinib resistance and patient outcome
Akcakaya P; Caramuta S; Ahlen J; Ghaderi M; Berglund E; Ostman A; Branstrom R; Larsson C; Lui W-O
Article: ONCOTARGET. 2014;5(20):10048-10057
TERT promoter mutations and gene amplification: Promoting TERT expression in Merkel cell carcinoma
Xie H; Liu T; Wang N; Bjornhagen V; Hoog A; Larsson C; Lui W-O; Xu D
Article: ONCOGENE. 2014;33(35):4407-4417
Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ
Bersani C; Xu L-D; Vilborg A; Lui W-O; Wiman KG
Article: EXPERIMENTAL CELL RESEARCH. 2014;326(2):315-325
Functional role of the Ca²⁺-activated Cl^- channel DOG1/TMEM16A in gastrointestinal stromal tumor cells
Berglund E; Akcakaya P; Berglund D; Karlsson F; Vukojevic V; Lee L; Bogdanovic D; Lui W-O; Larsson C; Zedenius J; Frobom R; Branstrom R
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2014;170(4):583-591
MicroRNA expression patterns associated with hyperfunctioning and non-hyperfunctioning phenotypes in adrenocortical adenomas
Velazquez-Fernandez D; Caramuta S; Ozata DM; Lu M; Hoog A; Backdahl M; Larsson C; Lui W-O; Zedenius J
Article: ANTI-CANCER DRUGS. 2014;25(4):415-422
Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells
Berglund E; Ubhayasekera SJKA; Karlsson F; Akcakaya P; Aluthgedara W; Ahlen J; Frobom R; Nilsson I-L; Lui W-O; Larsson C; Zedenius J; Bergquist J; Branstrom R
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(2):507-517
MicroRNA Expression Patterns Related to Merkel Cell Polyomavirus Infection in Human Merkel Cell Carcinoma
Xie H; Lee L; Caramuta S; Hoog A; Browaldh N; Bjornhagen V; Larsson C; Lui W-O
Article: PLOS ONE. 2014;9(12):e113740
Detection of Circulating hcmv-miR-UL112-3p in Patients with Glioblastoma, Rheumatoid Arthritis, Diabetes Mellitus and Healthy Controls
Mohammad A-A; Rahbar A; Lui W-O; Davoudi B; Catrina A; Stragliotto G; Mellbin L; Hamsten A; Ryden L; Yaiw K-C; Soderberg-Naucler C
Article: DEVELOPMENTAL BIOLOGY. 2013;383(2):253-263
miR-128 regulates non-myocyte hyperplasia, deposition of extracellular matrix and Islet1 expression during newt cardiac regeneration
Witman N; Heigwer J; Thaler B; Lui W-O; Morrison JI
Article: BLOOD CANCER JOURNAL. 2013;3(10):e152
Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma
Caramuta S; Lee L; Ozata DM; Akcakaya P; Georgii-Hemming P; Xie H; Amini R-M; Lawrie CH; Enblad G; Larsson C; Berglund M; Lui W-O
Article: GENES CHROMOSOMES & CANCER. 2013;52(10):895-911
miRNA-214 is related to invasiveness of human non-small cell lung cancer and directly regulates alpha protein kinase 2 expression
Salim H; Arvanitis A; de Petris L; Kanter L; Haag P; Zovko A; Ozata DM; Lui W-O; Lundholm L; Zhivotovsky B; Lewensohn R; Viktorsson K
Article: ENDOCRINE-RELATED CANCER. 2013;20(4):551-564
Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma
Caramuta S; Lee L; Ozata DM; Akcakaya P; Xie H; Hoog A; Zedenius J; Backdahl M; Larsson C; Lui W-O
Article: EXPERIMENTAL CELL RESEARCH. 2013;319(8):1229-1238
Evidence for Ca²⁺-regulated ATP release in gastrointestinal stromal tumors
Berglund E; Berglund D; Akcakaya P; Ghaderi M; Dare E; Berggren P-O; Kohler M; Aspinwall CA; Lui W-O; Zedenius J; Larsson C; Branstrom R
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2013;20(4):440-446
A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells
Johnsson P; Ackley A; Vidarsdottir L; Lui W-O; Corcoran M; Grander D; Morris KV
Article: PLOS ONE. 2012;7(10):e46990
miR-205 Expression Promotes Cell Proliferation and Migration of Human Cervical Cancer Cells
Xie H; Zhao Y; Caramuta S; Larsson C; Lui W-O
Article: ENDOCRINE-RELATED CANCER. 2011;18(6):643-655
The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma
Ozata DM; Caramuta S; Velazquez-Fernandez D; Akcakaya P; Xie H; Hoog A; Zedenius J; Backdahl M; Larsson C; Lui W-O
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2011;39(2):311-318
miR-185 and miR-133b deregulation is associated with overall survival and metastasis in colorectal cancer
Akcakaya P; Ekelund S; Kolosenko I; Caramuta S; Ozata DM; Xie H; Lindforss U; Olivecrona H; Lui W-O
Article: PLOS ONE. 2011;6(3):e14757
Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP)
Hashemi J; Worrall C; Vasilcanu D; Fryknas M; Sulaiman L; Karimi M; Weng W-H; Lui W-O; Rudduck C; Axelson M; Jernberg-Wiklund H; Girnita L; Larsson O; Larsson C
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010;130(8):2062-2070
MicroRNA Expression Profiles Associated with Mutational Status and Survival in Malignant Melanoma
Caramuta S; Egyhazi S; Rodolfo M; Witten D; Hansson J; Larsson C; Lui W-O
Article: BMC BIOLOGY. 2010;8:58
Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls.
Witten D; Tibshirani R; Gu SG; Fire A; Lui W-O
Article: JOURNAL OF MOLECULAR DIAGNOSTICS. 2009;11(5):420-429
Profiling and discovery of novel miRNAs from formalin-fixed, paraffin-embedded melanoma and nodal specimens.
Ma Z; Lui W-O; Fire A; Dadras SS
Article: CANCER RESEARCH. 2008;68(17):7156-7164
CREB3L2-PPARγ fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis
Lui W-O; Zeng L; Rehmann V; Deshpande S; Tretiakova M; Kaplan EL; Leibiger I; Leibiger B; Enberg U; Hoog A; Larsson C; Kroll TG
Article: ONCOGENE. 2008;27(14):2015-2026
MicroRNA expression signature of human sarcomas.
Subramanian S; Lui WO; Lee CH; Espinosa I; Nielsen TO; Heinrich MC; Corless CL; Fire AZ; van de Rijn M
Article: CANCER RESEARCH. 2007;67(13):6031-6043
Patterns of known and novel small RNAs in human cervical cancer.
Lui W-O; Pourmand N; Patterson BK; Fire A
Article: ENDOCRINE-RELATED CANCER. 2007;14(2):381-391
A PCR-based expression signature of malignancy in follicular thyroid tumors
Foukakis T; Gusnanto A; Au AYM; Hoog A; Lui W-O; Larsson C; Wallin G; Zedenius J
Article: THYROID. 2007;17(4):289-301
Molecular cytogenetic profiles of novel and established human anaplastic thyroid carcinoma models
Lee J-J; Foukakis T; Hashemi J; Grimelius L; Heldin N-E; Wallin G; Rudduck C; Lui W-O; Hoog A; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2006;29(5):1173-1182
A dog pedigree with familial medullary thyroid cancer
Lee J-J; Larsson C; Lui W-O; Hoog A; Von Euler H
Article: ONCOGENE. 2006;25(22):3186-3195
The insulin-like growth factor-1 receptor inhibitor PPP produces only very limitedresistance in tumor cells exposed to long-term selection
Vasilcanu D; Weng W-H; Girnita A; Lui W-O; Vasilcanu R; Axelson M; Larsson O; Larsson C; Girnita L
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2006;91(3):1143-1149
The Ras effector NORE1A is suppressed in follicular thyroid carcinomas with a PAX8-PPARγ fusion
Foukakis T; Au AYM; Wallin G; Geli J; Forsberg L; Clifton-Bligh R; Robinson BG; Lui WO; Zedenius J; Larsson C
Article: CLINICAL CANCER RESEARCH. 2005;11(17):6198-6204
Prognostic impact of immunohistochemical expression of ezrin in highly malignant soft tissue sarcomas
Weng WH; Åhlén J; Åström K; Lui WO; Larsson C
Article: ONCOGENE. 2005;24(8):1467-1476
Expression profiling reveals a distinct transcription signature in follicular thyroid carcinomas with a PAX8-PPARγ fusion oncogene
Lui WO; Foukakis T; Lidén J; Thoppe SR; Dwight T; Höög A; Zedenius J; Wallin G; Reimers M; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(1):141-149
Molecular cytogenetic characterization of primary cultures and established cell lines from non-medullary thyroid tumors
Foukakis T; Thoppe SR; Lagercrantz S; Dwight T; Weng WH; Svensson A; Höög A; Zedenius J; Wallin G; Lui WO; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(1):5-16
Loss of chromosome 13q is a frequently acquired event in genetic progression of soft tissue sarcomas in the abdominal cavity
Weng WH; Lerner M; Grander D; Åhlén J; Villablanca A; Pang ST; Wejde J; Lui WO; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2004;24(6):1419-1425
Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells
Appelskog IB; Ammerpohl O; Svechnikova IG; Lui WO; Almqvist PM; Ekström TJ
Article: CANCER GENETICS. 2004;150(1):27-32
Characterization of large chromosome markers in a malignant fibrous histiocytoma by spectral karyotyping, comparative genomic hybridization (CGH), and array CGH
Weng WH; Wejde J; Åhlén J; Pang ST; Lui WO; Larsson C
Article: CYTOGENETIC AND GENOME RESEARCH. 2004;106(1):28-32
Analysis of the cytogenetic stability of the human embryonal kidney cell line 293 by cytogenetic and STR profiling approaches
Bylund L; Kytölä S; Lui WO; Larsson C; Weber G
Article: CANCER CELL. 2003;4(5):405-413
The t(1;3) breakpoint-spanning involved in clear cell renal cell genes LSAMP and NORE1 are carcinomas
Chen JD; Lui WO; Vos MD; Clark GJ; Takahashi M; Schoumans J; Khoo SK; Petillo D; Lavery T; Sugimura J; Astuti D; Zhang C; Kagawa S; Maher ER; Larsson C; Alberts AS; Kanayama HO; Teh BT
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2003;88(9):4440-4445
Involvement of the PAX8/peroxisome proliferator-activated receptor γ rearrangement in follicular thyroid tumors
Dwight T; Thoppe SR; Foukakis T; Lui WO; Wallin G; Höög A; Frisk T; Larsson C; Zedenius J
Article: BRITISH JOURNAL OF CANCER. 2003;89(4):720-726
Gain of 17q in malignant fibrous histiocytoma is associated with a longer disease-free survival and a low risk of developing distant metastasis
Weng WH; Åhlén J; Lui WO; Brosjö O; Pang ST; von Rosen A; Auer G; Larsson O; Larsson C
Article: CANCER GENETICS. 2003;141(1):43-48
Molecular cytogenetic characterization of four commonly used cell lines derived from Hodgkin lymphoma
Berglund M; Flordal E; Gullander J; Lui WO; Larsson C; Lagercrantz S; Enblad G
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2002;21(6):1197-1204
Identifying cancer-related genes in nasopharyngeal carcinoma cell lines using DNA and mRNA expression profiling analyses
Guo X; Lui WO; Qian CN; Chen JD; Gray SG; Rhodes D; Haab B; Stanbridge E; Wang HM; Hong MH; Min HQ; Larsson C; Teh BT
Article: ENDOCRINOLOGIST. 2002;12(6):491-496
A pair of monozygotic twins with Klinefelters syndrome and early onset diabetes mellitus: A clinical and cytogenetic study
Tan MH; Lui WO; Rajasoorya C
Article: MODERN PATHOLOGY. 2002;15(8):807-816
Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization
Berglund M; Enblad G; Flordal E; Lui WO; Backlin C; Thunberg U; Sundström C; Roos G; Allander SV; Erlanson M; Rosenquist R; Larsson C; Lagercrantz S
Article: ONCOGENE. 2002;21(26):4181-4190
Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas
Yang K; Lui WO; Xie YT; Zhang AJ; Skytting B; Mandahl N; Larsson C; Larsson O
Article: ONCOGENE. 2002;21(7):1117-1122
Selective loss of chromosome 11 in pheochromocytomas associated with the VHL syndrome
Lui WO; Chen JD; Gläsker S; Bender BU; Madura C; Khoo SK; Kort E; Larsson C; Neumann HPH; Teh BT
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2001;19(3):451-457
High level amplification of 1p32-33 and 2p22-24 in small cell lung carcinomas
Lui WO; Tanenbaum DM; Larsson C
Article: INTERNATIONAL JOURNAL OF CANCER. 2001;92(6):824-831
Characterization of chromosomal abnormalities in uroepithelial carcinomas by G-banding, spectral karyotyping and fish analysis
Fadl-Elmula I; Kytölä S; Pan Y; Lui WO; Derienzo G; Forsberg L; Mandahl N; Gorunova L; Bergerheim USR; Heim S; Larsson C
Article: CANCER GENETICS. 2001;127(2):128-133
A highly aggressive primitive mesenchymal tumor with a translocation (1;19)(q12;q13.2)
Lui WO; Wejde J; Tani E; Brosjö O; Kytölä S; Larsson C
Article: JOURNAL OF MEDICAL GENETICS. 2001;38(3):165-170
Association of a novel constitutional translocation t(1q;3q) with familial renal cell carcinoma
Kanayama H; Lui WO; Takahashi M; Naroda T; Kedra D; Wong FI; Kuroki Y; Nakahori Y; Larsson C; Kagawa S; Teh BT
Article: GENES CHROMOSOMES & CANCER. 2001;30(2):187-195
5q11, 8p11, and 10q22 are recurrent chromosomal breakpoints in prostate cancer cell lines
Pan Y; Lui WO; Nupponen N; Larsson C; Isola J; Visakorpi T; Bergerheim USR; Kytölä S
Article: NATURE BIOTECHNOLOGY. 2000;18(9):1001-1005
Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays
Lindblad-Toh K; Tanenbaum DM; Daly MJ; Winchester E; Lui WO; Villapakkam A; Stanton SE; Larsson C; Hudson TJ; Johnson BE; Lander ES; Meyerson M
Article: CANCER GENETICS. 2000;121(1):61-66
Cytogenetic analysis of invasive breast cancer: a study of 27 Asian patients.
Tan PH; Lui WO; Ong P; Lau LC; Tao M; Chong Y
Article: CANCER GENETICS. 2000;119(2):109-112
Balanced translocation (3;7)(p25;q34):: Another mechanism of tumorigenesis in follicular thyroid carcinoma?
Lui WO; Kytölä S; Ånfalk L; Larsson C; Farnebo LO
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;5(1):33-41
Modulating IGFBP-3 expression by trichostatin A:: Potential therapeutic role in the treatment of hepatocellular carcinoma
Gray SG; Kytölä S; Lui WO; Larsson C; Ekström TJ
Article: CYTOGENETIC AND GENOME RESEARCH. 1999;87(3-4):225-232
Characterization of chromosomal abnormalities in prostate cancer cell lines by spectral karyotyping
Pan Y; Kytölä S; Farnebo F; Wang N; Lui WO; Nupponen N; Isola J; Visakorpi T; Bergerheim USR; Larsson C
Article: CANCER GENETICS. 1998;105(1):69-73
Acute promyelocytic leukemia with a dicentric chromosome involving chromosomes 11, 17, and 18.
Chong YY; Wong GC; Lau LC; Knight L; Lim P; Lui WO; Yong MH; Goh YT; Tan P
Article: CANCER GENETICS. 1998;103(1):65-67
A case of t(8;14) with total and partial trisomy 3 in Waldenstrom macroglobulinemia.
Chong YY; Lau LC; Lui WO; Lim P; Lim E; Tan PH; Tan P; Ong YY
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All other publications

Editorial comment: CANCERS. 2021;13(9):2259
New Insights into the Biological and Clinical Aspects of Merkel Cell Carcinoma.
Koljonen V; Lui W-O; Becker JC
Letter: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2012;10(10):2202-2205
Thrombin induces de novo protein synthesis of stromal cell-derived factor-1α but not angiostatin in human platelets
Huang Z; Rahman MF-U; Jiang L; Xie H; Hu H; Lui W-O; Li N
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):187
Altered expression of miR-205 affects cell proliferation in human cervical cancer
Xie H; Caramuta S; Larsson C; Lui WO
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):185
Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphomas
Caramuta S; Berglund M; Ozata D; Akcakaya P; Georgii-Hemming P; Xie H; Enblad G; Larsson C; Lui WO
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):224
The involvement of miR-483 and its host gene IGF2 in development of adrenal cortical carcinoma
Ozata D; Caramuta S; Akcakaya P; Xie HONG; Backdahl M; Larsson C; Lui W
Thesis / dissertation: 2002
Approaches for the localization and identification of human cancer genes
Lui, Wong-Onn
Letter: CANCER GENETICS. 2002;136(2):153-154
Myelodysplastic syndrome with transformation to AML-M7 in a 46,XX male patient.
Lau L-C; Lim P; Lee L-H; Hwang W; Lui W-O; Chong Y-Y

Employments

Professor, Department of Oncology-Pathology, Karolinska Institutet, 2024-
Senior Lecturer, Department of Oncology-Pathology, Karolinska Institutet, 2016-2024

Degrees and Education

Docent, Karolinska Institutet, 2014
Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2002

Supervisor

Hannah Björn Andtback, 2022
Yaije Yang, 2021

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