Vladana Vukojevic
- Department of Clinical Neuroscience
- Centre for Psychiatry Research at CNS
- Experimental alcohol- and drug dependence research – Vladana Vukojević research group
About me
Associate Professor of Biochemistry
Research
EXPERIMENTAL ALCOHOL AND DRUG DEPENDENCE RESEARCH
We study cellular and molecular mechanisms that underly alcohol use disorder (AUD), focusing on the opioid system role in its development and management. To this aim, we use and further develop quantitative time-resolved analytical methods with single-molecule sensitivity and integrative approaches from dynamical systems theory.
PERSONAL RESEARCH STATEMENT
My research, at the overarching level, focuses on understanding self-organization in chemical and biological systems using experimental and theoretical approaches. Self-organization is a universal property that is inherent to living organisms at all levels of their organization, from the cellular, tissue, organ, organism to the, supra individual, i.e. societal level. Self-organization also occurs in complex chemical and biochemical reaction systems in vitro when they proceed under conditions far from thermodynamic equilibrium. It arises through entangled networks of interconnected molecules that via molecular motion and chemical interactions give rise to positive and negative feedback loops through which specific molecules affect their own production/degradation. Such complex networks exhibit collective dynamical behavior that is a property of the network as a whole and cannot be predicted, not even in principle, by studying in isolation the kinetics of individual chemical/biochemical pathways that constitute the network, thus necessitating nondestructive studies of chemical kinetics in complex reaction mixtures in vitro and in live cells. To quantitatively and nondestructively characterize the kinetics of fast dynamical processes in complex chemical systems and in live cells/tissue ex vivo, I use and further develop advanced fluorescence microscopy and correlation spectroscopy methods. In addition, I am using mechanistic mathematical modeling and approaches from dynamical systems theory to understand how individual processes in complex biochemical networks are integrated to yield a coherent response at the organism level. My most important contributions to science are briefly summarized below.
CONTRIBUTION TO SCIENCE
Functional Fluorescence Microscopy Imaging (fFMI)
My work on the advancement of fluorescence microscopy and correlation spectroscopy approaches for quantitative characterization of fast dynamical processes in live cells/tissues, started by contributing to the development of an instrumental setup for confocal laser scanning microscopy with improved sensitivity [1]. This advancement enabled us to quantitatively characterize the kinetics of transcription factor-DNA interactions in live salivary glands of Drosophila and establish that the Hox transcription factor Sex Combs Reduced (Scr) finds its target genes in the nucleus of a living cell via a purely stochastic process – the homeodomain associates/dissociates rapidly (in the ms range) with/from nonspecific binding sites, whereas it remains bound for seconds or minutes at specific binding sites [2]. Our most recent work on methods development includes the development of massively parallel fluorescence correlation spectroscopy integrated with fluorescence lifetime imaging microscopy (mpFCS/FLIM) [3-5]. This method enables quantitative, scanning-free confocal fluorescence microscopy imaging and spatial-mapping of the heterogeneous distribution of molecules i.e., their concentration and diffusion/size, directional motion, local environment sensing, detection and characterization of molecular interactions, conformational changes, discrimination of spectrally similar fluorophores [3-5].
- Vukojević V, Heidkamp M, Ming Y, Johansson B, Terenius L, Rigler R. Quantitative single-molecule imaging by Confocal Laser Scanning Microscopy. Proc Natl Acad Sci USA, 2008, 105:18176-18181. doi: 10.1073/pnas.0809250105
- Vukojević V, Papadopoulos DK, Terenius L, Gehring W, Rigler R. Quantitative study of synthetic Hox transcription factor–DNA interactions in live cells. Proc Natl Acad Sci USA 2010, 107:4087-4092. doi: 10.1073/pnas.0914612107
- Krmpot AJ, Nikolić SN, Oasa S, Papadopoulos DK, Vitali M, Oura M, Mikuni S, Thyberg P, Tisa S, Kinjo M, Nilsson L, Terenius L, Rigler R, Vukojević V. Functional Fluorescence Microscopy Imaging (fFMI). Quantitative Scanning-Free Confocal Fluorescence Microscopy for the Characterization of Fast Dynamic Processes in Live Cells. Analytical Chemistry 2019, 91(17): 11129-11137. doi: 10.1021/acs.analchem.9b01813
- Oasa S, Krmpot AJ, Nikolic SN, Clayton AHA, Tsigelny IF, Changeux JP, Terenius L, Rigler R, Vukojevic V. Dynamic Cellular Cartography: Mapping the Local Determinants of Oligodendrocyte Transcription Factor 2 (OLIG2) Function in Live Cells Using Massively Parallel Fluorescence Correlation Spectroscopy Integrated with Fluorescence Lifetime Imaging Microscopy (mpFCS/FLIM). Anal Chem. 2021, 93(35):12011-12021. doi: 10.1021/acs.analchem.1c02144
- Nikolić SN, Oasa S, Krmpot AJ, Terenius L, Belić MR, Rigler R, Vukojević V. Mapping the Direction of Nucleocytoplasmic Transport of Glucocorticoid Receptor (GR) in Live Cells Using Two-Foci Cross-Correlation in Massively Parallel Fluorescence Correlation Spectroscopy (mpFCS). Anal Chem. 2023 95(41):15171-15179. doi: 10.1021/acs.analchem.3c01427
Quantitative transcription factor-DNA interactions and pharmacological studies in live cells
Methodology advancements have enabled us to quantitatively characterize the kinetics of transcription factor-DNA interactions in live salivary glands of Drosophila and establish that the Hox transcription factor Sex Combs Reduced (Scr) finds its target genes in the nucleus of live cells via rapid (in the millisecond range) homeodomain association/dissociation reactions with/from nonspecific binding sites, whereas it remains bound for seconds or minutes at specific binding sites [1] and to reveal an auto-regulatory switching mechanisms for Hox-mediated transcription activation/deactivation [2]. They have also enabled us to conduct precise quantitative pharmacological studies in live cells. In particular, we have quantitatively characterized the action of allosteric modulators of oligodendrocyte transcription factor 2 (OLIG2) dimerization [3] and were instrumental in revealing that CT-179, a small-molecule inhibitor of OLIG2 dimerization that is a promising drug candidate for treating Sonic hedgehog (Shh) medulloblastoma, the most common primary central nervous system (CNS) tumor in children, acts by disrupting OLIG2 homodimerization [4].- Vukojević V, Papadopoulos DK, Terenius L, Gehring W, Rigler R. Quantitative study of synthetic Hox transcription factor–DNA interactions in live cells. Proc Natl Acad Sci USA 2010 107(9):4087-4092. doi: 10.1073/pnas.0914612107
- Papadopoulos DK, Skouloudaki K, Engström Y, Terenius L, Rigler R, Zechner C, Vukojević V, Tomancak P. Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch. Development 2019 146(12): dev168179. doi: 10.1242/dev.168179
- Oasa S, Vukojević V, Rigler R, Tsigelny IF, Changeux JP, Terenius L. A strategy for designing allosteric modulators of transcription factor dimerization. Proc Natl Acad Sci U S A. 2020 117(5): 2683-2686. doi: 10.1073/pnas.1915531117
- Li Y, Lim C, Dismuke T, Malawsky DS, Oasa S, Bruce ZC, Offenhäuser C, Baumgartner U, D'Souza RCJ, Edwards SL, French JD, Ock LSH, Nair S, Sivakumaran H, Harris L, Tikunov AP, Hwang D, Alicea Pauneto CDM, Maybury M, Hassall T, Wainwright B, Kesari S, Stein G, Piper M, Johns TG, Sokolsky-Papkov M, Terenius L, Vukojević V, McSwain LF, Gershon TR, Day BW. Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179. Nat Commun. 2025 16(1):1091. doi: 10.1038/s41467-024-54861-3
Turnover of intermediates during amyloid-β aggregation towards early diagnosis of amyloid diseases
I have contributed to laying the foundation for the development of Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) imaging for simultaneous detection of amyloid-β and lipids in brain tissue preparations [1, 2], developed a new method to monitor the turnover of intermediates during amyloid-β aggregation [3], successfully used this method to measure the concentration and size of structured amyloidogenic protein nanoplaques in blood serum [4] and characterize conformation-sensitive and sequence-independent monoclonal antibodies (mAbs) [5].
- Solé-Domènech S, Sjövall P, Vukojević V, Fernando R, Codita A, Salve S, Bogdanović N, Mohammed AH, Hammarström P, Nilsson KP, LaFerla FM, Jacob S, Berggren PO, Giménez-Llort L, Schalling M, Terenius L, Johansson B. Localization of Cholesterol, Amyloid and Glia in Alzheimer’s Disease Transgenic Mouse Brain Tissue Using Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) and Immunofluorescence Imaging. Acta Neuropathologica, 2012 125:145-157. doi: 10.1007/s00401-012-1046-9
- Carlred L, Gunnarsson A, Solé-Domènech S, Johansson B, Vukojević V, Terenius L, Codita A, Winblad B, Schalling M, Höök F, Sjövall. Simultaneous Imaging of Amyloid-β and Lipids in Brain Tissue using Antibody-Coupled Liposomes and Time-of-Flight Secondary Ion Mass Spectrometry. J. Am. Chem. Soc. 2014 136:9973-9981. doi: 10.1021/ja5019145
- Tiiman A, Jarvet J, Gräslund A, Vukojević V. Heterogeneity and turnover of intermediates during amyloid-β (Aβ) peptide aggregation studied by Fluorescence Correlation Spectroscopy Biochemistry, 2015 54:7203-7211. doi: 10.1021/acs.biochem.5b00976
- Tiiman A, Jelić V, Jarvet J, Järemo P, Bogdanović N, Rigler R, Terenius L, Gräslund A, Vukojević V. Amyloidogenic nanoplaques in blood serum of patients with Alzheimer’s disease revealed by time-resolved Thioflavin T fluorescence intensity fluctuation analysis. J. Alzheimer's Dis. 2019 68: 571-582. doi: 10.3233/JAD-181144
- Bonito-Oliva A, Schedin-Weiss S, Younesi SS, Tiiman A, Adura C, Paknejad N, Brendel M, Romin Y, Parchem RJ, Graff C, Vukojević V, Tjernberg LO, Terenius L, Winblad B, Sakmar TP, Graham WV. Conformation-specific antibodies against multiple amyloid protofibril species from a single amyloid immunogen. J Cell Mol Med. 2019 23(3):2103-2114. doi: 10.1111/jcmm.14119
Ethanol effects on opioid receptor lateral dynamics and spatial organization at the nanoscale level
Our study of ethanol (alcohol) effects on opioid receptor lateral organization and dynamics in the plasma membrane has shown that ethanol and naltrexone exert an opposite effect on the lateral dynamics of the mu-opioid (MOP) receptor, and that pretreatment with naltrexone is protective against ethanol effects on MOP receptor lateral mobility [1, 2]. We could verify using electrophysiology that ethanol alters opioid regulation of Ca2+ influx through L-type Ca2+ channels [3] and showed that it also changes the spatial organization of proteins and lipids in the plasma membrane at the nanoscale level [4, 5].
- Gruol DL, Nelson TE, Michaels S, Vukojević V, Ming Y, Terenius L. Ethanol Alters Opioid Regulation of Ca2+ Influx through L-type Ca2+ Channels in PC12 Cells. Alcohol Clin Exp Res. 2012 36(3):443-456. doi: 10.1111/j.1530-0277.2011.01631.x
- Tobin SJ, Cacao EE, Hong DW, Terenius L, Vukojević V, Jovanović-Talisman T. Nanoscale Effects of Ethanol and Naltrexone on Protein Organization in the Plasma Membrane Studied by Photoactivated Localization Microscopy (PALM). PLoS One. 2014 9:e87225. doi: 10.1371/journal.pone.0087225
- Rogacki MK, Golfetto O, Tobin SJ, Li T, Biswas S, Jorand R, Zhang H, Radoi V, Ming Y, Svenningsson P, Ganjali D, Wakefield DL, Sideris A, Small AR, Terenius L, Jovanović-Talisman T, Vukojević V. Dynamic lateral organization of opioid receptors (kappa, muwt and muN40D) in the plasma membrane at the nanoscale level. Traffic 2018 19(9): 690-709. doi: 10.1111/tra.12582
- Tobin SJ, Wakefield DL, Terenius L, Vukojević V, Jovanović-Talisman T. Ethanol and Naltrexone Have Distinct Effects on the Lateral Nano-organization of Mu and Kappa Opioid Receptors in the Plasma Membrane. ACS Chem. Neurosci. 2019 10(1): 667-676. doi: 10.1021/acschemneuro.8b00488
- Oasa S, Sezgin E, Ma Y, Horne DA, Radmilović MD, Jovanović-Talisman T, Martin-Fardon R, Vukojević V, Terenius L. Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane. Transl Psychiatry. 2024 Nov 24;14(1):477. doi: 10.1038/s41398-024-03172-8
Predictive modeling of the dynamic self-regulation of Hypothalamic-Pituitary-Adrenal (HPA) axis activity under normal physiology and stress
Building on my experience of working with complex chemical systems and my knowledge of dynamical systems theory, we are working on the development of mathematical models of HPA axis to better understand how self-regulation of HPA axis arises through neurochemical transformations and how it is perturbed under conditions of acute and chronic stress [1-4].
- Čupić Ž, Marković VM, Maćešić S, Stanojević A, Damjanović S, Vukojević V, Kolar-Anić Lj. Dynamic transitions in a model of the hypothalamic-pituitary-adrenal (HPA) axis. Chaos 2016 26:033111. doi: 10.1063/1.4944040
- Čupić Ž, Stanojević A, Marković VM, Kolar-Anić L, Terenius L, Vukojević V. The HPA axis and ethanol: a synthesis of mathematical modelling and experimental observations. Addict. Biol. 2017 22(6):1486-1500. doi: 10.1111/adb.12409
- Abulseoud OA, Ho MC, Choi D-S, Stanojević A, Čupić Ž, Kolar-Anić Lj, Vukojević V. Corticosterone oscillations during mania induction in the lateral hypothalamic kindled rat experimental observations and mathematical modelling. PLoS One 2017, 12(5):e0177551. doi: 10.1371/journal.pone.0177551
- Stanojević A, Marković VM, Čupić Ž, Kolar-Anić Lj, Vukojević V. Advances in mathematical modelling of the hypothalamic–pituitary–adrenal (HPA) axis dynamics and the neuroendocrine response to stress. Current Opinion in Chemical Engineering 2018, 21:84–95. doi:10.1016/j.coche.2018.04.003
Non-canonical mechanisms of dynorphin peptides action
My work on FCS application to study neuropeptides interaction with live cells has led to discovering the potential of dynorphin neuropeptides to accumulate in artificial membranes and in the plasma membrane of live cells, causing defects in lipid arrangement and facilitating content exchange with the surroundings via non-canonical, receptor independent, mechanisms of action [1-4].
- Marinova Z*, Vukojević V*, Surcheva S, Yakovleva T, Cebers G, Pasikova N, Usynin I, Hugonin L, Fang W, Hallberg M, Hirschberg D, Bergman T, Langel U, Hauser KF, Pramanik A, Aldrich JV, Gräslund A, Terenius L, Bakalkin G. Translocation of dynorphin neuropeptides across the plasma membrane. A putative mechanism of signal transmission. J. Biol. Chem. 2005 280:26360-26370. doi: 10.1074/jbc.M412494200
- Hugonin L, Vukojević V, Bakalkin G, Gräslund A. Calcium influx into phospholipid vesicles caused by dynorphin neuropeptides. BBA-Biomembranes, 2008 1778:1267–1273. doi: 10.1016/j.bbamem.2008.02.00
- Hugonin L, Vukojević V, Bakalkin G, Gräslund A. Membrane leakage induced by dynorphins. FEBS Lett. 2006 580:3201-3205. doi: 10.1016/j.febslet.2006.04.078
- Maximyuk O, Khmyz V, Lindskog C-J, Vukojević V, Ivanova T, Bazov I, Hauser KF, Bakalkin G, Krishtal O. Plasma membrane poration by opioid neuropeptides: a possible mechanism of pathological signal transduction. Cell Death Dis. 2015 6:e1683. doi: 10.1038/cddis.2015.39
Oscillatory reactions: Advancing mechanistic insights and harnessing autocatalytic feed-back loops for quantitative analyte analysis with improved sensitivity
Experimental studies of detailed kinetic mechanisms underlying oscillatory chemical and biochemical reactions are challenging. Dedicated methods are therefore needed that enable us to obtain quantitative information that can be used to understand the causal connectivity and correlations among chemical species that constitute the investigated system. One such method that I have adopted since its insception is Quenching of Small-Amplitude Limit Cycle Oscillations, i.e., Quenching Analysis (QA) [1, 2]. QA is specifically designed to take the advantage of the oscillatory dynamics that emerges in the vicinity of a supercritical Hopf bifurcation and harness it to acquire unique quantitative information about the investigated system that can easily be compared with model predictions. By comparing the experimentally derived quenching concentrations and quenching phases with results obtained from mechanistic models, one can determine whether key reaction pathways are correctly identified and incorporated in the model of the reaction mechanism and assess how realistically the model reflects the true mechanism of the investigated system. Furthermore, one can harness the power of autocatalytic feedback loops in non-linear chemical systems to achieve quantitative analyte analysis with improved sensitivity [3].- Vukojević V, Sørensen PG, Hynne F. Quenching analysis of the Briggs-Rauscher reaction. J. Phys. Chem. 1993 97 (16):4091-4100. doi: 10.1021/j100118a027
- Vukojević V, Graae Sørensen P, Hynne F. Predictive Value of a Model of the Briggs−Rauscher Reaction Fitted to Quenching Experiments. J. Phys. Chem. 1996 100 (43):17175-17185. doi: 10.1021/jp960785o
- Vukojević V, Pejić N, Stanisavljev D, Anić S, Kolar-Anić Lj. Determination of Cl-, Br-, I-, Mn2+, Malonic Acid and Quercetin by Perturbation of a
Nonequilibrium Stationary State in the Bray-Liebhafsky Reaction. The Analyst, 1999 124:147-153. doi.org/10.1039/A807608A
Teaching
As an educator, I aim to significantly contribute to the advancement of individually tailored doctoral education at KI and its internationalization. By teaching advanced analytical methods, I enable PhD students to conduct ambitious and innovative research that pushes the frontiers of knowledge and prepares them to address complex global challenges in their respective fields using these experimental techniques.
- I have designed and teach at KI the doctoral course "Functional Fluorescence Microscopy Imaging in Biomedical Research", which has been running since 2010.
- I have been engaged as an Invited Lecturer at the Hokkaido Summer Institute since its inception in 2016. This program brings together world leading researchers with proven educational and research records to provide educational courses in cooperation with faculty members from Hokkaido University, Sapporo, Japan.
- I am a Visiting Professor at the Faculty of Physical Chemistry, University of Belgrade, Serbia since 2011.
- I work with pedagogical development and support course organizers within the doctoral program Allergy, Immunology and Inflammation (Aii) to further improve their educational practices by implementing pedagogical approaches and effectively designing their courses using the long-distance teaching and learning platform Canvas to develop a student-centred didactic environment that facilitates learning.
Articles
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 2025Li T; Vukojevic V; Oasa S; Bai Y; Yang Y; Li H; Tang Y; Terenius L; Hokfelt T; Svenningsson P; Xu Z-QD
- Article: AUTOPHAGY. 2025;21(7):1523-1543Shi H; Yang Y; Gao J; Kumar S; Xie H; Chen Z; Lyu J; Sihto H; Koljonen V; Vega-Rubin-de-Celis S; Vukojevic V; Farnebo F; Bjornhagen V; Hoog A; Juhlin CC; Lee L; Wickstroem M; Becker JC; Johnsen JI; Larsson C; Lui W-O
- Article: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 2025;1869(7):130809Oasa S; Stoyanov B; Hamada Y; Nikolic SN; Krmpot AJ; Kitamura A; Vukojevic V
- Article: ADVANCED SCIENCE. 2025;12(25):e2416784Niu G; Toma MA; Geara J; Bian X; Chen Y; Luo L; Wang Q; Xiao Y; Vij M; Piipponen M; Liu Z; Oasa S; Zhang L; Schlesinger D; Vegvari A; Li D; Wang A; Vukojevic V; Elsasser SJ; Sommar P; Landen XN
- Article: NATURE COMMUNICATIONS. 2025;16(1):1091Li Y; Lim C; Dismuke T; Malawsky DS; Oasa S; Bruce ZC; Offenhaeuser C; Baumgartner U; D'Souza RCJ; Edwards SL; French JD; Ock LSH; Nair S; Sivakumaran H; Harris L; Tikunov AP; Hwang D; Alicea Pauneto CDM; Maybury M; Hassall T; Wainwright B; Kesari S; Stein G; Piper M; Johns TG; Sokolsky-Papkov M; Terenius L; Vukojevic V; Mcswain LF; Gershon TR; Day BW
- Article: TRANSLATIONAL PSYCHIATRY. 2024;14(1):477Oasa S; Sezgin E; Ma Y; Horne DA; Radmilovic MD; Jovanovic-Talisman T; Martin-Fardon R; Vukojevic V; Terenius L
- Journal article: ATHEROSCLEROSIS. 2024;395:118368Stoisavljevic S; Waden K; Buckler A; Lengquist M; Roy J; Vukojevic V; Bogdanovic N; Marlevi D; Matic L
- Article: EXPERIMENTAL CELL RESEARCH. 2023;433(2):113858Branstrom R; Vukojevic V; Lu M; Shabo I; Mun H-C; Conigrave AD; Farnebo L-O; Larsson C
- Article: ANALYTICAL CHEMISTRY. 2023;95(41):15171-15179Nikolic SN; Oasa S; Krmpot AJ; Terenius L; Belic MR; Rigler R; Vukojevic V
- Article: CELL AND BIOSCIENCE. 2023;13(1):142Johansson B; Oasa S; Soria AM; Tiiman A; Soderberg L; Amandius E; Moller C; Lannfelt L; Terenius L; Gimenez-Llort L; Vukojevic V
- Article: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2023;244:125312Radmilovic MD; Drvenica IT; Rabasovic MD; Ilic VL; Pavlovic D; Oasa S; Vukojevic V; Peric M; Nikolic SN; Krmpot AJ
- Article: SCIENTIFIC REPORTS. 2023;13(1):11834Kitamura A; Oasa S; Kawaguchi H; Osaka M; Vukojevic V; Kinjo M
- Journal article: ALCOHOL. 2023;109:103-104Čupić Ž; Jayaram-Lindström N; Terenius L; Kolar-Anić L; Hammarberg A; Vukojević V
- Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(9):1575-1584Oasa S; Kouznetsova VL; Tiiman A; Vukojevic V; Tsigelny IF; Terenius L
- Journal article: FASEB JOURNAL. 2022;36(S1)Oasa S; Krmpot A; Nikolic S; Clayton A; Tsigelny I; Changeux J; Terenius L; Rigler R; Vukojevic V
- Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42(5):659-676Rykaczewska U; Zhao Q; Saliba-Gustafsson P; Lengquist M; Kronqvist M; Bergman O; Huang Z; Lund K; Waden K; Pons Vila Z; Caidahl K; Skogsberg J; Vukojevic V; Lindeman JHN; Roy J; Hansson GK; Treuter E; Leeper NJ; Eriksson P; Ehrenborg E; Razuvaev A; Hedin U; Matic L
- Article: MOLECULES. 2022;27(7):2350Radoi V; Jakobsson G; Palada V; Nikosjkov A; Druid H; Terenius L; Kosek E; Vukojevic V
- Article: JOURNAL OF ALZHEIMERS DISEASE. 2022;86(3):1459-1470Aksnes M; Aass HCD; Tiiman A; Terenius L; Bogdanovi N; Vukojevi V; Knapskog A-B
- Article: ACS BIO & MED CHEM AU. 2021;1(1):11-20Laurent AJ; Bindslev N; Vukojevic V; Terenius L
- Article: FASEB JOURNAL. 2021;35(12):e22055Li T; Oasa S; Ciruela F; Terenius L; Vukojevic V; Svenningsson P
- Article: ANALYTICAL CHEMISTRY. 2021;93(35):12011-12021Oasa S; Krmpot AJ; Nikolic SN; Clayton AHA; Tsigelny IF; Changeux J-P; Terenius L; Rigler R; Vukojevic V
- Article: TRANSLATIONAL NEURODEGENERATION. 2021;10(1):18Aksnes M; Aass HCD; Tiiman A; Edwin TH; Terenius L; Bogdanovic N; Vukojevic V; Knapskog A-B
- Article: BIOCHEMISTRY. 2021;60(9):678-688Leppert A; Tiiman A; Kronqvist N; Landreh M; Abelein A; Vukojevic V; Johansson J
- Article: FRONTIERS IN AGING NEUROSCIENCE. 2021;12:608628Aksnes M; Tiiman A; Edwin TH; Terenius L; Bogdanovic N; Vukojevic V; Knapskog A-B
- Journal article: ALZHEIMERS & DEMENTIA. 2020;16(S4)Aksnes M; Tiiman A; Edwin TH; Terenius L; Bogdanovic N; Vukojevic V; Knapskog A
- Article: JOURNAL OF ALZHEIMERS DISEASE. 2020;77(2):831-842Aksnes M; Muller EG; Tiiman A; Edwin TH; Terenius L; Revheim M-E; Vukojevic V; Bogdanovic N; Knapskog A-B
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(16):E5742-5742Ristivojevic MK; Grundstrom J; Apostolovic D; Radomirovic M; Jovanovic V; Radoi V; Kiewiet MBG; Vukojevic V; Velickovic TC; van Hage M
- Article: JOURNAL OF AFFECTIVE DISORDERS. 2020;267:96-102Nassan M; Veldic M; Winham S; Frye MA; Larrabee B; Colby C; Biernacka J; Bellia F; Pucci M; Terenius L; Vukojevic V; D'Addario C
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(5):2683-2686Oasa S; Vukojevic V; Rigler R; Tsigelny IF; Changeux J-P; Terenius L
- Article: ANALYTICAL CHEMISTRY. 2019;91(17):11129-11137Krmpot AJ; Nikolic SN; Oasa S; Papadopoulos DK; Vitali M; Oura M; Mikuni S; Thyberg P; Tisa S; Kinjo M; Nilsson L; Terenius L; Rigler R; Vukojevic V
- Article: NEUROPHARMACOLOGY. 2019;152:51-57Hertz E; Terenius L; Vukojevic V; Svenningsson P
- Article: MOLECULAR GENETICS & GENOMIC MEDICINE. 2019;7(6):e666Lundin J; Markljung E; Korberg IB; Hofmeister W; Cao J; Nilsson D; Holmdahl G; Barker G; Anderberg M; Vukojevic V; Lindstrand A; Nordenskjold A
- Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;68(2):571-582Tiiman A; Jelic V; Jarvet J; Jaremo P; Bogdanovic N; Rigler R; Terenius L; Graslund A; Vukojevic V
- Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2019;23(3):2103-2114Bonito-Oliva A; Schedin-Weiss S; Younesi SS; Tiiman A; Adura C; Paknejad N; Brendel M; Romin Y; Parchem RJ; Graff C; Vukojevic V; Tjernberg LO; Terenius L; Winblad B; Sakmar TP; Graham WV
- Article: DEVELOPMENT. 2019;146(12):dev168179Papadopoulos DK; Skouloudaki K; Engstrom Y; Terenius L; Rigler R; Zechner C; Vukojevic V; Tomancak P
- Article: ACS CHEMICAL NEUROSCIENCE. 2019;10(1):667-676Tobin SJ; Wakefield DL; Terenius L; Vukojevic V; Jovanovic-Talisman T
- Article: SCIENTIFIC REPORTS. 2018;8(1):12684Ristivojevic MK; Grundstrom J; Tran TAT; Apostolovic D; Radoi V; Starkhammar M; Vukojevic V; Velickovic TC; Hamsten C; van Hage M
- Article: TRAFFIC. 2018;19(9):690-709Rogacki MK; Golfetto O; Tobin SJ; Li T; Biswas S; Jorand R; Zhang H; Radoi V; Ming Y; Svenningsson P; Ganjali D; Wakefield DL; Sideris A; Small AR; Terenius L; Jovanovic-Talisman T; Vukojevic V
- Journal article: PHOTOSYNTHESIS RESEARCH. 2018;135(1-3):141-142Moldenhauer M; Sluchanko NN; Tavraz NN; Junghans C; Buhrke D; Willoweit M; Chiappisi L; Schmitt F-J; Vukojevic V; Shirshin EA; Ponomarev VY; Paschenko VZ; Gradzielski M; Maksimov EG; Friedrich T
- Article: REACTION KINETICS MECHANISMS AND CATALYSIS. 2018;123(1):17-30Stanojevic A; Markovic VM; Macesic S; Kolar-Anic L; Vukojevic V
- Article: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2018;1860(2):491-504Vasconcelos L; Lehto T; Madani F; Radoi V; Hallbrink M; Vukojevic V; Langel U
- Article: RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY A. 2017;91(13):2600-2607Stanojevic A; Markovic VM; Cupic Z; Vukojevic V; Kolar-Anic L
- Article: BIOPHYSICAL JOURNAL. 2017;113(10):2249-2260Junghans C; Vukojevic V; Tavraz NN; Maksimov EG; Zuschratter W; Schmitt F-J; Friedrich T
- Article: ADDICTION BIOLOGY. 2017;22(6):1486-1500Cupic Z; Stanojevic A; Markovic VM; Kolar-Anic L; Terenius L; Vukojevic V
- Article: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2017;76:195-203D'Addario C; Shchetynsky K; Pucci M; Cifani C; Gunnar A; Vukojevic V; Padyukov L; Terenius L
- Article: PLOS ONE. 2017;12(5):e0177551Abulseoud OA; Ho MC; Choi D-S; Stanojevic A; Cupic Z; Kolar-Anic L; Vukojevic V
- Article: PLOS ONE. 2016;11(12):e0168276Assadi G; Vesterlund L; Bonfiglio F; Mazzurana L; Cordeddu L; Schepis D; Mjosberg J; Ruhrmann S; Fabbri A; Vukojevic V; Percipalle P; Salomons FA; Laurencikiene J; Torkvist L; Halfvarson J; D'Amato M
- Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(9):1947-1961Matic LP; Rykaczewska U; Razuvaev A; Sabater-Lleal M; Lengquist M; Miller CL; Ericsson I; Rohl S; Kronqvist M; Aldi S; Magne J; Paloschi V; Vesterlund M; Li Y; Jin H; Diez MG; Roy J; Baldassarre D; Veglia F; Humphries SE; de Faire U; Tremoli E; Odeberg J; Vukojevic V; Lehtio J; Maegdefessel L; Ehrenborg E; Paulsson-Berne G; Hansson GK; Lindeman JHN; Eriksson P; Quertermous T; Hamsten A; Hedin U
- Article: REACTION KINETICS MECHANISMS AND CATALYSIS. 2016;118(1):15-26Pejic N; Kolar-Anic L; Maksimovic J; Jankovic M; Vukojevic V; Anic S
- Article: CHAOS. 2016;26(3):033111Cupic Z; Markovic VM; Macesic S; Stanojevic A; Damjanovic S; Vukojevic V; Kolar-Anic L
- Article: MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA. 2016;33(1):1-28Markovic VM; Cupic Z; Macesic S; Stanojevic A; Vukojevic V; Kolar-Anic L
- Journal article: OPTOFLUIDICS MICROFLUIDICS AND NANOFLUIDICS. 2016;3(1)Junghans C; Schmitt F-J; Vukojević V; Friedrich T
- Article: BIOCHEMISTRY. 2015;54(49):7203-7211Tiiman A; Jarvet J; Graslund A; Vukojevic V
- Article: NEUROSCIENCE. 2015;310:723-730Xie J; Gizatullin R; Vukojevic V; Leopardi R
- Article: MECHANISMS OF DEVELOPMENT. 2015;138:218-225Papadopoulos DK; Krmpot AJ; Nikolic SN; Krautz R; Terenius L; Tomancak P; Rigler R; Gehring WJ; Vukojevic V
- Article: HUMAN MOLECULAR GENETICS. 2015;24(18):5069-5078Korberg IB; Hofmeister W; Markljung E; Cao J; Nilsson D; Ludwig M; Draaken M; Holmdahl G; Barker G; Reutter H; Vukojevic V; Kockum CC; Lundin J; Lindstrand A; Nordenskjold A
- Article: CELL DEATH & DISEASE. 2015;6(3):e1683Maximyuk O; Khmyz V; Lindskog C-J; Vukojevic V; Ivanova T; Bazov I; Hauser KF; Bakalkin G; Krishtal O
- Journal article: OPTOFLUIDICS MICROFLUIDICS AND NANOFLUIDICS. 2015;2(1):1-14Junghans C; Schmitt F-J; Vukojević V; Friedrich T
- Article: IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS. 2014;20(6):344-353Vitali M; Bronzi D; Krmpot AJ; Nikolic SN; Schmitt F-J; Junghans C; Tisa S; Friedrich T; Vukojevic V; Terenius L; Zappa F; Rigler R
- Article: EXPERIMENTAL CELL RESEARCH. 2014;326(2):315-325Berglund E; Akcakaya P; Berglund D; Karlsson F; Vukojevic V; Lee L; Bogdanovic D; Lui W-O; Larsson C; Zedenius J; Frobom R; Branstrom R
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2014;99(8):E1571-E1579Wang N; Xu D; Sofiadis A; Hoog A; Vukojevic V; Backdahl M; Zedenius J; Larsson C
- Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2014;136(28):9973-9981Carlred L; Gunnarsson A; Sole-Domenech S; Johansson B; Vukojevic V; Terenius L; Codita A; Winblad B; Schalling M; Hook F; Sjovall P
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2014;289(8):4660-4673Lundius EG; Vukojevic V; Hertz E; Stroth N; Cederlund A; Hiraiwa M; Terenius L; Svenningsson P
- Article: PLOS ONE. 2014;9(2):e87225Tobin SJ; Cacao EE; Hong DWW; Terenius L; Vukojevic V; Jovanovic-Talisman T
- Article: JOURNAL OF NEUROCHEMISTRY. 2013;124(3):410-417Lundius EG; Stroth N; Vukojevic V; Terenius L; Svenningsson P
- Article: ACTA NEUROPATHOLOGICA. 2013;125(1):145-157Sole-Domenech S; Sjovall P; Vukojevic V; Fernando R; Codita A; Salve S; Bogdanovic N; Mohammed AH; Hammarstrom P; Nilsson KPR; LaFerla FM; Jacob S; Berggren P-O; Gimenez-Llort L; Schalling M; Terenius L; Johansson B
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2012;1824(12):1401-1408Papadopoulos E; Collet J-F; Vukojevic V; Billeter M; Holmgren A; Graslund A; Vlamis-Gardikas A
- Article: PLOS ONE. 2012;7(5):e36448Haglund F; Lu M; Vukojevic V; Nilsson I-L; Andreasson A; Dzabic M; Branstrom R; Hoog A; Juhlin CC; Larsson C
- Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2012;36(3):443-456Gruol DL; Nelson TE; Hao C; Michael S; Vukojevic V; Ming Y; Terenius L
- Article: MOLECULAR AND CELLULAR BIOLOGY. 2011;31(19):4119-4128Arzenani MK; Zade AE; Ming Y; Vijverberg SJH; Zhang Z; Khan Z; Sadique S; Kallenbach L; Hu L; Vukojevic V; Ekstrom TJ
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011;411(1):208-212Marino A-M; Sofiadis A; Baryawno N; Johnsen JI; Larsson C; Vukojevic V; Ekstrom TJ
- Journal article: ALZHEIMERS & DEMENTIA. 2011;7(4S_Part_21):s725-s726Solé‐Domènech S; Sjövall P; Vukojevic V; Codita A; Salve S; Schalling M; LaFerla F; Giménez‐Llort L; Nilsson P; Hammarström P; Terenius L; Johansson B
- Article: METHODS IN MOLECULAR BIOLOGY. 2011;789:147-170Vukojević V; Gräslund A; Bakalkin G
- Article: ENDOCRINE JOURNAL. 2011;58(10):889-904Markovic VM; Cupic Z; Vukojevic V; Kolar-Anic L
- Article: LANGMUIR. 2010;26(18):14782-14787Vukojevic V; Bowen AM; Wilhelm K; Ming Y; Ce Z; Schleucher J; Hore PJ; Terenius L; Morozova-Roche LA
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(9):4093-4098Vukojevic V; Papadopoulos DK; Terenius L; Gehring WJ; Rigler R
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(9):4087-4092Papadopoulos DK; Vukojevic V; Adachi Y; Terenius L; Rigler R; Gehring WJ
- Article: INTERNATIONAL JOURNAL OF NONLINEAR SCIENCES AND NUMERICAL SIMULATION. 2009;10(11-12):1451-1472Jelic S; Cupic Z; Kolar-Anic L; Vukojevic V
- Article: FEBS JOURNAL. 2009;276(15):3975-3989Wilhelm K; Darinskas A; Noppe W; Duchardt E; Mok KH; Vukojevic V; Schleucher J; Morozova-Roche LA
- Article: PLOS ONE. 2008;3(12):e4008Vukojevic V; Ming Y; D'Addario C; Rigler R; Johansson B; Terenius L
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(47):18176-18181Vukojevic V; Heidkamp M; Ming Y; Johansson B; Terenius L; Rigler R
- Article: FASEB JOURNAL. 2008;22(10):3537-3548Vukojevic V; Ming Y; D'Addario C; Hansen M; Langel U; Schulz R; Johansson B; Rigler R; Terenius L
- Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2008;287(1-2):72-80Lu M; Forsberg L; Hoog A; Juhlin CC; Vukojevic V; Larsson C; Conigrave AD; Delbridge LW; Gill A; Bark C; Farnebo L-O; Branstrom R
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2008;1778(5):1267-1273Hugonin L; Vukojevic V; Bakalkin G; Graslund A
- Article: ANALYTICA CHIMICA ACTA. 2007;582(2):367-374Pejic ND; Blagojevic SM; Anic SR; Vukojevic VB; Mijatovic MD; Ciric JS; Markovic ZS; Markovic SD; Kolar-Anic LZ
- Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2007;43(2):718-721Kuntic V; Pejic N; Ivkovic B; Vujic Z; Ilic K; Micic S; Vukojevic V
- Article: JOURNAL OF PHYSICAL CHEMISTRY A. 2006;110(34):10361-10368Schmitz G; Kolar-Anic L; Anic S; Grozdic T; Vukojevic V
- Article: MONATSHEFTE FUR CHEMIE. 2006;137(6):803-810Kuntic V; Stanojevic M; Holclajtner-Antunovic I; Uskokovic-Markovic S; Mioc U; Todorovic M; Jovanovic T; Vukojevic V
- Article: FEBS LETTERS. 2006;580(13):3201-3205Hugonin L; Vukojevic V; Bakalkin G; Graslund A
- Article: JOURNAL OF PROTEOME RESEARCH. 2006;5(4):1017-1023Woods AS; Kaminski R; Oz M; Wang Y; Hauser K; Goody R; Wang HYJ; Jackson SN; Zeitz P; Zeitz KP; Zolkowska D; Schepers R; Nold M; Danielson J; Gräslund A; Vukojevic V; Bakalkin G; Basbaum A; Shippenberg T
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(28):26360-26370Marinova Z; Vukojevic V; Surcheva S; Yakovleva T; Cebers G; Pasikova N; Usynin I; Hugonin L; Fang WJ; Hallberg M; Hirschberg D; Bergman T; Langel Ü; Hauser KF; Pramanik A; Aldrich JV; Terenius L; Bakalkin G
- Article: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2005;381(3):775-780Pejic N; Blagojevic S; Anic S; Vukojevic V; Kolar-Anic L
- Article: JOURNAL OF THE SERBIAN CHEMICAL SOCIETY. 2005;70(5):753-763Kuntic V; Pejic N; Micic S; Vukojevic V; Vujic Z; Malesev D
- Journal article: AIP CONFERENCE PROCEEDINGS. 2004;742(1):3-8Kolar‐Anić L; Vukojević V; Pejić N; Grozdić T; Anić S
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004;318(2):615-624Yakovleva T; Kolesnikova L; Vukojevic V; Gileva I; Tan-No K; Austen M; Lüscher B; Ekström TJ; Terenius L; Bakalkin G
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004;316(4):1150-1155Vukojevic V; Yakovleva T; Terenius L; Pramanik A; Bakalkin G
- Article: MICROCHIMICA ACTA. 2003;143(4):261-267Pejic N; Anic S; Kuntic V; Vukojevic V; Kolar-Anic L
- Article: JOURNAL OF PHYSICAL CHEMISTRY A. 2002;106(23):5618-5625Stanisavljev DR; Vukojevic VB
- Article: PHYSICAL CHEMISTRY CHEMICAL PHYSICS. 2002;4(8):1276-1283Vukojevic V; Anic S; Kolar-Anic L
- Article: PHARMAZIE. 2001;56(11):897-898Vukojevic V; Pejic N; Stanisavljev D; Anic S; Kolar-Anic L
- Article: JOURNAL OF PHYSICAL CHEMISTRY A. 2000;104(46):10731-10739Vukojevic V; Anic S; Kolar-Anic L
- Article: MONATSHEFTE FUR CHEMIE. 2000;131(7):769-777Kuntic V; Malesev D; Radovic Z; Vukojevic V
- Article: ANALYST. 1999;124(2):147-152Vukojevic VB; Pejic ND; Stanisavljev DR; Anic SR; Kolar-Anic LZ
- Article: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 1998;46(12):5139-5142Kuntic VS; Malesev DL; Radovic ZV; Kosanic MM; Mioc UB; Vukojevic VB
- Article: JOURNAL OF PHYSICAL CHEMISTRY A. 1998;102(35):6887-6891Stanisavljev D; Begovic N; Vukojevic V
- Article: JOURNAL OF PHYSICAL CHEMISTRY. 1996;100(43):17175-17185Vukojevic V; Sorensen PG; Hynne F
- Journal article: JOURNAL OF PHYSICAL CHEMISTRY. 1993;97(16):4091-4100VUKOJEVIC V; SORENSEN PG; HYNNE F
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All other publications
- Preprint: RES SQ. 2023;RES SQTerenius L; Oasa S; Sezgin E; Ma Y; Horne D; Radmiković M; Jovanović-Talisman T; Martin-Fardon R; Vukojevic V
- Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S99Oasa S; Kouznetsova V; Masich S; Tiiman A; Vukojevic V; Tsigelny I; Terenius L
- Preprint: RES SQ. 2023;RES SQLi Y; Lim C; Dismuke T; Malawsky DS; Oasa S; Bruce ZC; Offenhäuser C; Baumgartner U; D'Souza RCJ; Edwards SL; French JD; Ock LSH; Nair S; Sivakumaran H; Harris L; Tikunov AP; Hwang D; Del Mar Alicea Pauneto C; Maybury M; Hassall T; Wainwright B; Kesari S; Stein G; Piper M; Johns TG; Sokolsky-Papkov M; Terenius L; Vukojević V; Gershon TR; Day BW
- Preprint: BIORXIV. 2022Kitamura A; Oasa S; Kawaguchi H; Osaka M; Vukojević V; Kinjo M
- Conference publication: 2021Vukojevic V
- Review: DISEASE MODELS & MECHANISMS. 2020;13(12):dmm046516Auer JMT; Stoddart JJ; Christodoulou I; Lima A; Skouloudaki K; Hal HNI; Vukojevic V; Papadopoulos DK
- Conference publication: BIOPHYSICAL JOURNAL. 2020;118(3):307AOasa S; Krmpot A; Nikolic S; Terenius L; Rigler R; Vukojevic V
- Review: CURRENT OPINION IN CHEMICAL ENGINEERING. 2018;21:84-95Stanojevic A; Markovic VM; Cupic Z; Kolar-Anic L; Vukojevic V
- Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38Rykaczewska U; Saliba-Gustafsson P; Lengquist M; Kronqvist M; Lund K; Caidahl K; Skogsberg J; Vukojevic V; Lindeman JH; Paulsson-Berne G; Hansson GK; Leeper N; Ehrenborg E; Razuvaev A; Hedin U; Matic LP
- Published conference paper: PHOTOSYNTHESIS RESEARCH. 2018;135(1-3):125-139Moldenhauer M; Sluchanko NN; Tavraz NN; Junghans C; Buhrke D; Willoweit M; Chiappisi L; Schmitt F-J; Vukojevic V; Shirshin EA; Ponomarev VY; Paschenko VZ; Gradzielski M; Maksimov EG; Friedrich T
- Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):392A-393AGraslund A; Tiiman A; Jarvet J; Vukojevic V
- Book chapter: ENCYCLOPEDIA OF SIGNALING MOLECULES. 2018;p. 3656-3665Vukojević V; Ming Y; Jovanović-Talisman T; Terenius L
- Conference publication: ALLERGY. 2017;72:796Krstic M; Apostolovic D; Tran T; Grundstrom J; Radoi V; Vukojevic V; Velickovic CT; Hamsten C; Van Hage M
- Preprint: BIORXIV. 2017Junghans C; Vukojević V; Tavraz N; Maksimov E; Zuschratter W; Schmitt F-J; Friedrich T
- Conference publication: ALCOHOL. 2017;60:238Cupic Z; Stanojevic A; Markovic VM; Kolar-Anic L; Terenius L; Vukojevic V
- Conference publication: ALCOHOL. 2017;60:227D'Addario C; Shchetynsky K; Pucci M; Cifani C; Gunnar A; Vukojevic V; Padyukov L; Terenius L
- Preprint: BIORXIV. 2017Papadopoulos D; Skouloudaki K; Engstrom Y; Terenius L; Rigler R; Zechner C; Vukojevic V; Tomancak P
- Conference publication: BIOPHYSICAL JOURNAL. 2017;112(3):160AGraslund A; Tiiman A; Jarvet J; Vukojevic V
- Conference publication: MOLECULAR BIOLOGY OF THE CELL. 2017;28Tobin SJ; Golfetto O; Biswas S; Wakefield DL; Cacao EE; Vukojevic V; Terenius L; Jovanovic-Talisman T
- Book chapter: ENCYCLOPEDIA OF SIGNALING MOLECULES. 2017;p. 1-10Vukojević V; Ming Y; Jovanović-Talisman T; Terenius L
- Conference publication: ALLERGY. 2016;71:284Tran TAT; Grundstrom J; Krstic M; Vukojevic V; Apostolovic D; Hamsten C; Gafvelin G; van Hage M
- Published conference paper: BIOINTERPHASES. 2016;11(2):02A312Carlred L; Vukojevic V; Johansson B; Schalling M; Hook F; Sjovall P
- Conference publication: BIOPHYSICAL JOURNAL. 2016;110(3):484AGolfetto O; Biswas S; Jorand R; Zhang H; Tobin SJ; Ganjali D; Sideris A; Small AR; Vukojevic V; Jovanovic-Talisman T
- Review: INTERNATIONAL JOURNAL OF ONCOLOGY. 2015;47(3):817-839Belkic K; Cohen M; Wilczek B; Andersson S; Berman AH; Marquez M; Vukojevic V; Mints M
- Conference publication: PROCEEDINGS OF SPIE - THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING. 2015;9536:95360o-95360o-9-95360OKrmpot AJ; Nikolic SN; Vitali M; Papadopoulos DK; Oasa S; Thyberg P; Tisa S; Kinjo M; Nilsson L; Gehring WJ; Terenius L; Rigler R; Vukojevic V
- Conference publication: BIOPHYSICAL JOURNAL. 2015;108(2):96AJorand R; Golfetto O; Biswas S; Tobin SJ; Zhang H; Vukojevic V; Jovanovic-Talisman T
- Conference publication: 2015;:95360oKrmpot AJ; Nikolić SN; Vitali M; Papadopoulos DK; Oasa S; Thyberg P; Tisa S; Kinjo M; Nilsson L; Gehring WJ; Terenius L; Rigler R; Vukojević V
- Conference publication: ACTA PHYSIOLOGICA. 2014;211:12Krishtal O; Maximyuk O; Khmyz V; Lindskog C; Vukojevic V; Ivanova T; Rajnisz A; Solecka J; Lipkowski A; Hauser K; Bakalkin G
- Conference publication: ALCOHOL. 2014;48(2):189D'Addario C; Vukojevic V; Tantimonaco M; Gunnar A; Maccarrone M; Terenius L
- Conference publication: ALCOHOL. 2014;48(2):185Cupic Z; Kolar-Anic L; Terenius L; Vukojevic V
- Conference publication: ALCOHOL. 2014;48(2):182-183Jovanovic-Talisman T; Tobin SJ; Cacao EE; Hong DWW; D'Addario C; Terenius L; Vukojevic V
- Book chapter: BIO-NANOIMAGING. 2014;p. 453-462Vukojević V; Klechikov A; Morozova-Roche LA
- Review: JOURNAL OF THE SERBIAN CHEMICAL SOCIETY. 2013;78(11):1671-1688Jovanovic-Talisman T; Vukojevic V
- Book chapter: LIPOPROTEINS - ROLE IN HEALTH AND DISEASES. 2012;p.Vukojević V; Morozova-Roche LA
- Book chapter: ENCYCLOPEDIA OF SIGNALING MOLECULES. 2012;p. 1304-1312Vukojević V; Ming Y; Terenius L
- Conference publication: PHARMACOLOGICAL REPORTS. 2011;63(1):237-238Yakovleva T; Khmyz V; Maximyuk O; Marinova Z; Vukojevic V; Krishtal O; Bakalkin G
- Book chapter: METHODS FOR THE DISCOVERY AND CHARACTERIZATION OF G PROTEIN-COUPLED RECEPTORS: NEUROMETHODS. 2011;p. 359-377Vukojević V; Ming Y; Terenius L
- Conference publication: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2010;34(6):135AGruol DL; Vukojevic V; Ming Y; Michaels S; Terenius L
- Book chapter: P53: MOLECULAR BIOLOGY INTELLIGENCE UNIT. 2010;p. 127-141Vukojevic V; Yakovleva T; Bakalkin G
- Conference publication: CELLULAR ONCOLOGY. 2009;31(2):103-104Arzenani MK; Vijverberg S; Vukojevic V; Ekstrom TJ
- Published conference paper: RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY A. 2007;81(9):1371-1373Popovic-Bijelic A; Bijelic G; Kolar-Anic L; Vukojevic V
- Conference publication: FEBS JOURNAL. 2007;274:107Vukojevic V; Ming Y; D'Addario C; Johansson B; Rigler R; Terenius L
- Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2005;1048:457-460Popovic-Bijelic A; Bijelic G; Kolar-Anic L; Vukojevic V
- Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2005;62(5):535-550Vukojevic V; Pramanik A; Yakovleva T; Rigler R; Terenius L; Bakalkin G
- Conference publication: BIOPHYSICAL JOURNAL. 2005;88(1):422AHugonin L; Vukojevic V; Gräslund A
- Conference publication: JOURNAL OF PHYSICAL CHEMISTRY B. 2002;106(23):11AStanisavljev DR; Vukojevic VB
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Grants
- VINNOVA22 May 2023 - 6 September 2024
- Swedish Research Council1 January 2023 - 31 December 2026This interdisciplinary research proposal at the interface between biophysical chemistry, optics/photonics, cell biology and molecular medicine, aims to solidify instrumentation and further advance a new methodology for quantitative spatio-temporally resolved fluorescence microscopy imaging via massively parallel Fluorescence Correlation Spectroscopy (mpFCS) that we have recently developed. The methodology, which has the ultimate, single-molecule sensitivity, will be used in basic and translational studies to:Aim 1a. Dissect in live cells kinetic mechanisms through which gene transcription networks self-adjust their essential variables and control their own biological function.Aim 1b. Provide in live cells quantitative biophysical data and mechanistic insights on how the functional dynamics of oligodendrocyte transcription factor (OLIG2) can be rescued by treatment with novel prospective drug candidates. Aim 2. Implement this new technology in a translational research study aiming to develop a reliable and affordable non-immune, blood-based assay for early diagnosis of amyloid diseases, such as Alzheimer’s disease (AD).Aim 3a. Development of a system for massively parallel dual-color Fluorescence Cross-Correlation Spectroscopy (mpFCCS).Aim 3b. Develop a fiber optic probe to allow parallelized FCS recordings in behaving animals.
- Swedish Research Council1 January 2022 - 31 December 2025The most common neurodegenerative disease is Alzheimer´s disease, in which the amyloid-ß (Aß) peptide aggregates to amyloid fibers that accumulate in plaques in the human brain. Key aspects of the disease are still unclear of which the following are addressed in this proposal:(i) Aß oligomers have been correlated with the severity of the disease but their structure is controversial. Here, we will generate structural models of several oligomers in aqueous solu tion and in interaction with membranes using isotope-edited infrared (IR) spectroscopy. (ii) Lipids are important modulators of Aß aggregation and are elevated in and around plaques. However, their role in plaque development is unclear. Therefore, we will map the biochemical composition of plaques from human brain with higher (20 nm) resolution than before using nanoscale IR spectroscopy.(iii) Little is known about Aß´s interaction with other amyloidogenic polypeptides. This will be studied with a particular focus on structure and morphology of the co-aggregates. For this, we will combine the above approaches.(iv) There is presently no cure for AD but promising anti-amyloid peptides are known. We will study their interaction with Aß as under (iii) for a further knowledge-based improvement of their design.In addition to pioneering methodological development, our approach will further the molecular understanding of AD in areas that are difficult to study with other methods.
- Drug targeting the dynamics of opioid systems in alcohol dependence molecule sensitivityNIH/NIAAA14 May 2021 - 15 May 2025
- VINNOVA3 May 2021 - 17 December 2021
- Qatar National Research Fund15 April 2021 - 15 April 2024
- Swedish Research Council1 January 2019 - 31 December 2022
- Swedish Research Council1 January 2018 - 31 December 2020
- Swedish Research Council1 January 2018 - 31 December 2018
- Swedish Research Council1 January 2017 - 31 December 2019
- Swedish Research Council1 January 2013 - 31 December 2015
- Early diagnosis of proteinopathies using massively parallel nano-spectroscopy with single-molecule sensitivity. Advanced clinical diagnostics for the development of personalized treatmentsQatar National Research Fund (QNRF)
Employments
- Principal Researcher, Department of Clinical Neuroscience, Karolinska Institutet, 2022-2026
Degrees and Education
- Docent, Karolinska Institutet, 2011
- Associate Professor, Biochemistry, Karolinska Institutet, 2011
- PhD, Physical Chemistry, Bifurcation and Perturbation Analysis of the Bray-Liebhafsky Reaction, Faculty of Physical Chemistry, University of Belgrade, 2000
Committee work
- Member, Selection Committee Member, Human Frontier Science Program (HFSP), International Human Frontier Science Program Organization, https://www.hfsp.org/, 2024-2024
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2024-2024
- Vice chair, Review panel, NT-O Biomedical Engineering, The Swedish Research Council, https://www.vr.se/english/applying-for-funding/how-applications-are-assessed/review-panels/review-panel/2021-01-25-nt-o-biomedical-engineering.html, 2024-2024
- Member, Selection Committee Member, Human Frontier Science Program (HFSP), International Human Frontier Science Program Organization, https://www.hfsp.org/, 2023-2023
- Vice chair, The Course and Programme Committee, Karolinska Institutet, https://staff.ki.se/the-course-and-programme-committee, 2023-2026
- Member, Internationalisation Board, Karolinska Institutet, https://staff.ki.se/internationalisation-board, 2023-2024
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2023-2023
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2022-2022
- Member, Selection Committee Member, Human Frontier Science Program (HFSP), International Human Frontier Science Program Organization, https://www.hfsp.org/, 2022-2022
- Member, Selection Committee Member, Human Frontier Science Program (HFSP), International Human Frontier Science Program Organization, https://www.hfsp.org/, 2021-2024
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2021-2021
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2020-2020
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2019-2019
- Member, The Course and Programme Committee, 2019-2023
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2018-2018
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2017-2017
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2016-2016
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2015-2015
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2014-2014
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group, 2013-2013
- Member, Steering Group, Doctoral programme in Allergy, immunology and inflammation (Aii), Karolinska Institutet, https://staff.ki.se/aii-steering-group
Visiting research fellowships
- Visiting Researcher, University of Copenhagen, 1990-1991
Thesis evaluation
- Chinmaya Venugopal Srambickal, Examination board member, Royal Institute of Technology, Super-resolution microscopy – photophysical implications and applications, https://www.diva-portal.org/smash/get/diva2:1858733/FULLTEXT01.pdf, 2024
- Maryam Sanaee, Examination board member, Royal Institute of Technology, Photoluminescence-based characterization of bioengineered nanovesicles and erbium emitters, https://kth.diva-portal.org/smash/get/diva2:1824352/FULLTEXT02.pdf, 2024
- Martina Damenti, Examination board member, Royal Institute of Technology, Investigation of Neuronal Protein Trafficking at the Molecular Scale, https://kth.diva-portal.org/smash/record.jsf?aq2=%5B%5B%5D%5D&c=26&af=%5B%5D&searchType=LIST_COMING&sortOrder2=title_sort_asc&query=&language=sv&pid=diva2%3A1812369&aq=%5B%5B%5D%5D&sf=all&aqe=%5B%5D&sortOrder=author_sort_asc&onlyFullText=false&noOfRows=50&dswid=5550, 2023
- Baris Demirbay, Examination board member, Royal Institute of Technology, Concepts and biomedical applications of excitation-modulated transient state monitoring of fluorescence emitters, https://kth.diva-portal.org/smash/record.jsf?pid=diva2%3A1757894&dswid=3191, 2023
- Kristin Feltmann, Examination board member, Karolinska Institutet, The role of the dopamine system in the ability of (-)-OSU6162 to reduce voluntary alcohol drinking and binge-eating in the rat, https://openarchive.ki.se/xmlui/handle/10616/46100, 2017
- Bill Söderström, Examination board member, Stockholm University, Fluorescence Studies of Cell Division in Escherichia coli, https://www.diva-portal.org/smash/get/diva2:711789/FULLTEXT02.pdf, 2014
- Heike Hevekerl, Examination board member, Royal Institute of Technology, Fluorescence-based methods to probe long-lived transient states for biomolecular studies, https://kth.diva-portal.org/smash/record.jsf?pid=diva2%3A710771&dswid=-8559, 2014
- Johan Strömquist, Examination board member, Royal Institute of Technology, Fluorescence studies of membranes - proteins and lipids, their dynamics and interactions, https://kth.diva-portal.org/smash/record.jsf?pid=diva2%3A418097&dswid=-3230, 2011