Tamás Pongrácz

About me
Publications
Public outreach and news

Research

Glyco(proteo)mics, Integrative omics, Bioinformatics

Articles

Journal article: JACS AU. 2024;4(5):1696-1708

The Human Blood N-Glycome: Unraveling Disease Glycosylation Patterns.

Pongracz T; Mayboroda OA; Wuhrer M
Journal article: JOURNAL OF TRANSLATIONAL MEDICINE. 2024;22(1):456

Autoimmune hepatitis displays distinctively high multi-antennary sialylation on plasma N-glycans compared to other liver diseases.

Pongracz T; Biewenga M; Stoelinga AEC; Bladergroen MR; Nicolardi S; Trouw LA; Wuhrer M; de Haan N; van Hoek B
Journal article: EBIOMEDICINE. 2023;87:104408

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees.

Van Coillie J; Pongracz T; Rahmöller J; Chen H-J; Geyer CE; van Vught LA; Buhre JS; Šuštić T; van Osch TLJ; Steenhuis M; Hoepel W; Wang W; Lixenfeld AS; Nouta J; Keijzer S; Linty F; Visser R; Larsen MD; Martin EL; Künsting I; Lehrian S; von Kopylow V; Kern C; Lunding HB; de Winther M; van Mourik N; Rispens T; Graf T; Slim MA; Minnaar RP; Bomers MK; Sikkens JJ; Vlaar APJ; van der Schoot CE; den Dunnen J; Wuhrer M; Ehlers M; Vidarsson G; Fatebenefratelli-Sacco Infectious Diseases Physici; UMC COVID-19 S3/HCW study group
Journal article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2022;20(12):3011-3025

Altered Fc glycosylation of anti-HLA alloantibodies in hemato-oncological patients receiving platelet transfusions.

van Osch TLJ; Pongracz T; Geerdes DM; Mok JY; van Esch WJE; Voorberg J; Kapur R; Porcelijn L; Kerkhoffs J-LH; van der Meer PF; van der Schoot CE; de Haas M; Wuhrer M; Vidarsson G
Journal article: CELL REPORTS MEDICINE. 2022;3(11):100818

Afucosylation of HLA-specific IgG1 as a potential predictor of antibody pathogenicity in kidney transplantation.

Bharadwaj P; Shrestha S; Pongracz T; Concetta C; Sharma S; Le Moine A; de Haan N; Murakami N; Riella LV; Holovska V; Wuhrer M; Marchant A; Ackerman ME
Journal article: GLYCOCONJUGATE JOURNAL. 2022;39(3):335-344

Antibody glycosylation in COVID-19.

Pongracz T; Vidarsson G; Wuhrer M
Journal article: EBIOMEDICINE. 2022;78:103957

Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19.

Pongracz T; Nouta J; Wang W; van Meijgaarden KE; Linty F; Vidarsson G; Joosten SA; Ottenhoff THM; Hokke CH; de Vries JJC; Arbous SM; Roukens AHE; Wuhrer M; BEAT-COVID; COVID-19 groups
Journal article: NATURE IMMUNOLOGY. 2022;23(1):23-32

Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19.

Roukens AHE; Pothast CR; König M; Huisman W; Dalebout T; Tak T; Azimi S; Kruize Y; Hagedoorn RS; Zlei M; Staal FJT; de Bie FJ; van Dongen JJM; Arbous SM; Zhang JLH; Verheij M; Prins C; van der Does AM; Hiemstra PS; de Vries JJC; Janse JJ; Roestenberg M; Myeni SK; Kikkert M; Yazdanbakhsh M; Heemskerk MHM; Smits HH; Jochems SP; in collaboration with BEAT-COVID group; in collaboration with COVID-19 LUMC group
Journal article: FRONTIERS IN IMMUNOLOGY. 2022;13:1020844

mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses compared to an adenovirus-based vaccine.

Buhre JS; Pongracz T; Künsting I; Lixenfeld AS; Wang W; Nouta J; Lehrian S; Schmelter F; Lunding HB; Dühring L; Kern C; Petry J; Martin EL; Föh B; Steinhaus M; von Kopylow V; Sina C; Graf T; Rahmöller J; Wuhrer M; Ehlers M
Journal article: FRONTIERS IN IMMUNOLOGY. 2022;13:993354

The IgG glycome of SARS-CoV-2 infected individuals reflects disease course and severity.

Siekman SL; Pongracz T; Wang W; Nouta J; Kremsner PG; da Silva-Neto PV; Esen M; Kreidenweiss A; Held J; Trapé ÁA; Fendel R; de Miranda Santos IKF; Wuhrer M; ImmunoCovid Consortium
Journal article: JOURNAL OF PROTEOMICS. 2021;238:104148

Profiling the proteoforms of urinary prostate-specific antigen by capillary electrophoresis - mass spectrometry.

Moran AB; Domínguez-Vega E; Nouta J; Pongracz T; de Reijke TM; Wuhrer M; Lageveen-Kammeijer GSM
Journal article: GLYCOCONJUGATE JOURNAL. 2021;38(2):157-166

The structure and role of lactone intermediates in linkage-specific sialic acid derivatization reactions.

Pongracz T; Verhoeven A; Wuhrer M; de Haan N
Journal article: HLA. 2019;94(5):415-424

Recombinant human monoclonal HLA antibodies of different IgG subclasses recognising the same epitope: Excellent tools to study differential effects of donor-specific antibodies.

Kramer CSM; Franke-van Dijk MEI; Priddey AJ; Pongrácz T; Gnudi E; Car H; Karahan GE; van Beelen E; Zilvold-van den Oever CCC; Rademaker HJ; de Haan N; Wuhrer M; Kosmoliaptsis V; Parren PWHI; Mulder A; Roelen DL; Claas FHJ; Heidt S
Journal article: MOLECULES. 2019;24(19):3617

Expanding the Reaction Space of Linkage-Specific Sialic Acid Derivatization.

Pongracz T; Wuhrer M; de Haan N
Journal article: JOURNAL OF SEPARATION SCIENCE. 2017;40(24):4825-4834

Advanced online mass spectrometry detection of proteins separated by capillary isoelectric focusing after sequential injection.

Páger C; Biherczová N; Ligetvári R; Berkics BV; Pongrácz T; Sándor V; Bufa A; Poór V; Vojs Staňová A; Kilár F

All other publications

Preprint: MEDRXIV. 2022

Afucosylation of HLA-specific IgG1 as a potential predictor of antibody pathogenicity in kidney transplantation

Bharadwaj P; Shrestha S; Pongracz T; Concetta C; Sharma S; Le Moine A; de Haan N; Murakami N; Riella L; Holovska V; Wuhrer M; Marchant A; Ackerman M
Preprint: BIORXIV. 2022

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not antigen-experienced vaccinees

Van Coillie J; Pongracz T; Rahmöller J; Chen H-J; Geyer C; van Vlught L; Buhre J; Šuštić T; van Osch T; Steenhuis M; Hoepel W; Wang W; Lixenfeld A; Nouta J; Keijzer S; Linty F; Visser R; Larsen M; Martin E; Künsting I; Lehrian S; von Kopylow V; Kern C; Lunding H; de Winther M; van Mourik N; Rispens T; Graf T; Slim M; Minnaar R; Bomers M; Sikkens J; Vlaar A; van der Schoot E; den Dunnen J; Wuhrer M; Ehlers M; Vidarsson G; the Fatebenefratelli-Sacco Infectious Diseases Phy
Preprint: MEDRXIV. 2021

Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19

Pongracz T; Nouta J; Wang W; van Meijgaarden K; Linty F; Vidarsson G; Joosten S; Ottenhoff T; Hokke C; de Vries J; Arbous S; Roukens A; Wuhrer M; BEAT-COVID groups; COVID-19 groups
Preprint: MEDRXIV. 2021

Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2 specific CD8 T cell responses following COVID-19

Roukens AHE; König M; Dalebout T; Tak T; Azimi S; Kruize Y; Pothast C; Hagedoorn R; Arbous S; Zhang J; Verheij M; Prins C; van der Does A; Hiemstra P; de Vries JJC; Janse J; Roestenberg M; Myeni S; Kikkert M; Heemskerk MHM; Yazdanbakhsh M; Smits H; Jochems S; BEAT-COVID group

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