Sven Nyrén

Publications
CV
Public outreach and news

Articles

Article: EUROPEAN JOURNAL OF RADIOLOGY OPEN. 2024;12:100558
Detection of acute pulmonary embolism using native repeated magnetic resonance imaging acquisitions under free-breathing and without respiratory or cardiac gating. A diagnostic accuracy study
Medson K; Paris RV; Fyrdahl A; Wiklund P; Nyren S; Westerlund E; Lindholm P
Article: ACADEMIC RADIOLOGY. 2024;31(2):572-581
Initial Clinical Images From a Second-Generation Prototype Silicon-Based Photon-Counting Computed Tomography System
Almqvist H; Crotty D; Nyren S; Yu J; Arnberg-Sandor F; Brismar T; Tovatt C; Linder H; Dagotto J; Fredenberg E; Tamm MY; Deak P; Fanariotis M; Bujila R; Holmin S
Article: FRONTIERS IN MEDICINE. 2024;11:1263511
Residual radiological opacities correlate with disease outcomes in ICU-treated COVID-19
Bjoernson M; Svensson AM; He C; Skoeld M; Nyren S; Nygren-Bonnier M; Bruchfeld J; Runold M; Jalde FC; Kistner A
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(17):13546
Mucins 3A and 3B Are Expressed in the Epithelium of Human Large Airway.
Merikallio H; Pincikova T; Kotortsi I; Karimi R; Li C-X; Forsslund H; Mikko M; Nyrén S; Lappi-Blanco E; Wheelock ÅM; Kaarteenaho R; Sköld MC
Article: ARCHIVES OF OSTEOPOROSIS. 2023;18(1):65
Patients' thoughts about assessment of fracture risk in a dental setting using FRAX-a qualitative interview study
Elleby C; Skott P; Theobald H; Nyren S; Salminen H
Article: ACTA RADIOLOGICA. 2023;64(4):1371-1380
Feasibility of monitoring the resolution of acute pulmonary embolism with non-contrast-enhanced magnetic resonance imaging at one day, one week, one, three, and six months
Medson K; Westerlund E; Paris RV; Fyrdahl A; Vidovic N; Nyren S; Lindholm P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(1):e2210214120
Phase-contrast virtual chest radiography
Haeggmark I; Shaker K; Nyren S; Al-Amiry B; Abadi E; Segars WP; Samei E; Hertz HM
Article: PLOS ONE. 2023;18(3):e0283564
Long term association of hip fractures by questions of physical health in a cohort of men and women
Elleby C; Skott P; Johansson S-E; Nyren S; Theobald H; Salminen H
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(6):941-956
Lung perfusion disturbances in nonhospitalized post-COVID with dyspnea-A magnetic resonance imaging feasibility study
Yu JZ; Granberg T; Shams R; Petersson S; Skold M; Nyren S; Lundberg J
Article: MOLECULAR ONCOLOGY. 2021;15(11):2941-2957
Multiplex immune protein profiling of fine-needle aspirates from patients with non-small-cell lung cancer reveals signatures associated with PD-L1 expression and tumor stage
Franzen B; Viktorsson K; Kamali C; Darai-Ramqvist E; Grozman V; Arapi V; Haag P; Kaminskyy VO; Hydbring P; Kanter L; Nyren S; Ekman S; De Petris L; Lewensohn R
Article: EUROPEAN JOURNAL OF ORAL SCIENCES. 2021;129(5):e12801
Two methods of evaluating mandibular trabecular pattern in intraoral radiographs and the association to fragility fractures during a 47-year follow up
Elleby C; Skott P; Jonasson G; Theobald H; Nyren S; Salminen H
Article: BMC NEPHROLOGY. 2021;22(1):297
Negative effects of iodine-based contrast agent on renal function in patients with moderate reduced renal function hospitalized for COVID-19
Kistner A; Tamm C; Svensson AM; Beckman MO; Strand F; Skold M; Nyren S
Article: NATURE COMMUNICATIONS. 2021;12(1):2417
COVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone system
Rysz S; Al-Saadi J; Sjostrom A; Farm M; Jalde FC; Platten M; Eriksson H; Klein M; Vargas-Paris R; Nyren S; Abdula G; Ouellette R; Granberg T; Fagerlund MJ; Lundberg J
Article: ACTA ONCOLOGICA. 2021;60(3):305-311
Extending hypofractionated stereotactic body radiotherapy to tumours larger than 70cc-effects and side effects
Grozman V; Onjukka E; Wersall P; Lax I; Tsakonas G; Nyren S; Lewensohn R; Lindberg K
Article: FRONTIERS IN MEDICINE. 2021;8:666723
Widespread Parenchymal Abnormalities and Pulmonary Embolism on Contrast-Enhanced CT Predict Disease Severity and Mortality in Hospitalized COVID-19 Patients
Jalde FC; Beckman MO; Svensson AM; Bell M; Skold M; Strand F; Nyren S; Kistner A
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2020;9(21):e018075
Abnormal Pulmonary Venous Filling: An Adjunct Feature in the Computed Tomography Pulmonary Angiogram Assessment of Chronic Thromboembolic Pulmonary Hypertension
Gopalan D; Nordgren-Rogberg A; Le EPV; Pavey H; Tarkin J; Nyren S; Auger W; Lindholm P
Article: RMD OPEN. 2020;6(2):e001278
Association between number and type of different ACPA fine specificities with lung abnormalities in early, untreated rheumatoid arthritis
Joshua V; Hensvold AH; Reynisdottir G; Hansson M; Cornillet M; Nogueira L; Serre G; Nyren S; Karimi R; Eklund A; Skold M; Grunewald J; Chatzidionysiou K; Catrina A
Article: LAKARTIDNINGEN. 2020;117:20086
[Covid-19 - radiologic and histologic features].
Mari Svensson A; Hansen T; Nyren S; Csatlós M; Brunnström H
Article: RHEUMATOLOGY. 2020;59(4):852-859
Secretory anti-citrullinated protein antibodies in serum associate with lung involvement in early rheumatoid arthritis
Ljungberg KR; Joshua V; Skogh T; Eklund A; Skold CM; Karimi R; Nyren S; Svard A; Catrina AI; Kastbom A
Article: THROMBOSIS JOURNAL. 2020;18(1):19
A case-report of widespread pulmonary embolism in a middle-aged male seven weeks after asymptomatic suspected COVID 19 infection
Beckman M; Nyren S; Kistner A
Article: RESPIRATORY RESEARCH. 2019;20(1):102
Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia differ from patients with asthma
Um-Bergstrom P; Hallberg J; Pourbazargan M; Berggren-Brostrom E; Ferrara G; Eriksson MJ; Nyren S; Gao J; Lilja G; Linden A; Wheelock AM; Melen E; Skold CM
Article: EUROPEAN JOURNAL OF RADIOLOGY OPEN. 2019;6:315-319
Primary diagnosis of pulmonary embolism with unenhanced MRI for patients not eligible for CTPA: Clinical outcome
Medson K; Vargas-Paris R; Nordgren-Rogberg A; Sigbergsdottir A; Nyren S; Lindholm P
Article: MAGNETIC RESONANCE IN MEDICINE. 2018;80(5):1847-1856
Pulmonary artery imaging under free-breathing using golden-angle radial bSSFP MRI: a proof of concept
Fyrdahl A; Paris RV; Nyren S; Holst K; Ugander M; Lindholm P; Sigfridsson A
Article: BRITISH JOURNAL OF RADIOLOGY. 2018;91(1087):20170683
Dependency of image quality on acquisition protocol and image processing in chest tomosynthesis-a visual grading study based on clinical data
Jadidi M; Bath M; Nyren S
Article: ACTA RADIOLOGICA OPEN. 2018;7(6):2058460118783013
Diffusion-weighted imaging in acute pulmonary embolism: a feasibility study
Paris RV; Skorpil M; Westerlund E; Lindholm P; Nyren S
Article: RESPIRATORY RESEARCH. 2018;19(1):39
Proteomic profiling of lung immune cells reveals dysregulation of phagocytotic pathways in female-dominated molecular COPD phenotype
Yang M; Kohler M; Heyder T; Forsslund H; Garberg HK; Karimi R; Grunewald J; Berven FS; Nyren S; Skold CM; Wheelock AM
Article: EUROPEAN JOURNAL OF RADIOLOGY OPEN. 2018;5:189-193
Optimizing diffusion-weighted magnetic resonance imaging for evaluation of lung tumors: A comparison of respiratory triggered and free breathing techniques
Swerkersson S; Grundberg O; Kolbeck K; Carlberg A; Nyren S; Skorpil M
Article: ACTA RADIOLOGICA OPEN. 2017;6(9):2058460117734244-205846011773424
How to train radiology residents to diagnose pulmonary embolism using a dedicated MRI protocol.
Nordgren Rogberg A; Nyrén S; Westerlund E; Lindholm P
Article: ACTA RADIOLOGICA. 2017;58(3):272-278
Detection of pulmonary embolism using repeated MRI acquisitions without respiratory gating: a preliminary study
Nyren S; Rogberg AN; Paris RV; Bengtsson B; Westerlund E; Lindholm P
Article: OSTEOPOROSIS INTERNATIONAL. 2017;28(1):179-187
Gait speed and one-leg standing time each add to the predictive ability of FRAX
Lundin H; Saaf M; Strender L-E; Nyren S; Johansson S-E; Salminen H
Article: EUROPEAN RESPIRATORY JOURNAL. 2017;49(1):1600345
Differences in regional air trapping in current smokers with normal spirometry
Karimi R; Tornling G; Forsslund H; Mikko M; Wheelock AM; Nyren S; Skold CM
Article: INTERNATIONAL JOURNAL OF COPD. 2017;12:35-48
Gender differences in the T-cell profiles of the airways in COPD patients associated with clinical phenotypes
Forsslund H; Yang M; Mikko M; Karimi R; Nyren S; Engvall B; Grunewald J; Merikallio H; Kaarteenaho R; Wahlstrom J; Wheelock AM; Skold CM
Article: CALCIFIED TISSUE INTERNATIONAL. 2016;99(4):333-339
High Serum Insulin-Like Growth Factor-Binding Protein 1 (IGFBP-1) is Associated with High Fracture Risk Independent of Insulin-Like Growth Factor 1 (IGF-I)
Lundin H; Saaf M; Strender L-E; Nyren S; Johansson S-E; Salminen H
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(9):1722-1727
Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis
Reynisdottir G; Olsen H; Joshua V; Engstrom M; Forsslund H; Karimi R; Skold CM; Nyren S; Eklund A; Grunewald J; Catrina AI
Article: JOURNAL OF THORACIC DISEASE. 2015;7(12):2226-2233
Biopsy testing in an inoperable, non-small cell lung cancer population-a retrospective, real-life study in Sweden
Koyi H; Johansson L; From J; Nyren S
Article: BRITISH JOURNAL OF RADIOLOGY. 2015;88(1053):20150057
Evaluation of a new system for chest tomosynthesis: aspects of image quality of different protocols determined using an anthropomorphic phantom
Jadidi M; Sundin A; Aspelin P; Bath M; Nyren S
Article: PLOS ONE. 2015;10(9):e0137535
Laser-Supported Dual Energy X-Ray Absorptiometry (DXL) Compared to Conventional Absorptiometry (DXA) and to FRAX as Tools for Fracture Risk Assessments
Lundin H; Torabi F; Saaf M; Strender L-E; Nyren S; Johansson S-E; Salminen H
Article: OSTEOPOROSIS INTERNATIONAL. 2014;25(4):1305-1311
One-leg standing time and hip-fracture prediction
Lundin H; Saaf M; Strender L-E; Nyren S; Johansson S-E; Salminen H
Article: RESPIRATORY RESEARCH. 2014;15(1):23
Lung density on high resolution computer tomography (HRCT) reflects degree of inflammation in smokers
Karimi R; Tornling G; Forsslund H; Mikko M; Wheelock AM; Nyren S; Skold CM
Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(1):31-39
Structural Changes and Antibody Enrichment in the Lungs Are Early Features of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis
Reynisdottir G; Karimi R; Joshua V; Olsen H; Hensvold AH; Harju A; Engstrom M; Grunewald J; Nyren S; Eklund A; Klareskog L; Skold CM; Catrina AI
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;131(3):743-751
Gender differences in the bronchoalveolar lavage cell proteome of patients with chronic obstructive pulmonary disease
Kohler M; Sandberg A; Kjellqvist S; Thomas A; Karimi R; Nyren S; Eklund A; Thevis M; Skold CM; Wheelock AM
Article: FERTILITY AND STERILITY. 2011;96(6):1508-1513
Randomized comparison of the influence of dietary management and/or physical exercise on ovarian function and metabolic parameters in overweight women with polycystic ovary syndrome
Nybacka A; Carlstrom K; Stahle A; Nyren S; Hellstrom PM; Hirschberg AL
Article: ANESTHESIOLOGY. 2010;113(6):1370-1375
Inhalation Anesthesia Increases V/Q Regional Heterogeneity during Spontaneous Breathing in Healthy Subjects
Nyren S; Radell P; Mure M; Petersson J; Jacobsson H; Lindahl SGE; Sanchez-Crespo A
Article: ANESTHESIOLOGY. 2010;112(3):682-687
Lung Ventilation and Perfusion in Prone and Supine Postures with Reference to Anesthetized and Mechanically Ventilated Healthy Volunteers
Nyren S; Radell P; Lindahl SGE; Mure M; Petersson J; Larsson SA; Jacobsson H; Sanchez-Crespo A
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2010;108(1):181-188
Nasal nitric oxide and regulation of human pulmonary blood flow in the upright position
Crespo AS; Hallberg J; Lundberg JO; Lindahl SGE; Jacobsson H; Weitzberg E; Nyren S
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2009;53(9):1158-1166
Iloprost inhalation redistributes pulmonary perfusion and decreases arterial oxygenation in healthy volunteers
Rimeika D; Sanchez-Crespo A; Nyren S; Lindahl SGE; Wiklund CU
Article: RESPIRATORY PHYSIOLOGY AND NEUROBIOLOGY. 2009;166(1):54-60
Regional lung blood flow and ventilation in upright humans studied with quantitative SPECT
Petersson J; Rohdin M; Sanchez-Crespo A; Nyren S; Jacobsson H; Larsson SA; Lindahl SGE; Linnarsson D; Neradilek B; Polissar NL; Glenny RW; Mure M
Article: RESPIRATORY PHYSIOLOGY AND NEUROBIOLOGY. 2007;156(3):293-303
Posture primarily affects lung tissue distribution with minor effect on blood flow and ventilation
Petersson J; Rohdin M; Sanchez-Crespo A; Nyren S; Jacobsson H; Larsson SA; Lindahl SGE; Linnarsson D; Neradilek B; Polissar NL; Glenny RW; Mure M
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2006;100(1):240-248
Paradoxical redistribution of pulmonary blood flow in prone and supine humans exposed to hypergravity
Petersson J; Rohdin M; Sánchez-Crespo A; Nyrén S; Jacobsson H; Larsson SA; Lindahl SGE; Linnarsson D; Glenny RW; Mure M
Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2005;94(5-6):646-651
Studies on inspiratory and expiratory glossopharyngeal breathing in breath-hold divers employing magnetic resonance imaging and spirometry
Lindholm P; Nyrén S
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2004;170(4):450-455
Regulation of regional lung perfusion by nitric oxide
Rimeika D; Nyrén S; Wiklund NP; Koskela LR; Torring A; Gustafsson LE; Larsson SA; Jacobsson H; Lindahl SGE; Wiklund CU
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2004;96(3):1127-1136
Physiological evaluation of a new quantitative SPECT method measuring regional ventilation and perfusion
Petersson J; Sánchez-Crespo A; Rohdin M; Montmerle S; Nyrén S; Jacobsson H; Larsson SA; Lindahl SGE; Linnarsson D; Glenny RW; Mure M
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2002;29(7):863-875
A novel quantitative dual-isotope method for simultaneous ventilation and perfusion lung SPET
Sánchez-Crespo A; Petersson J; Nyren S; Mure M; Glenny RW; Thorell JO; Jacobsson H; Lindahl SGE; Larsson SA
Article: CLINICAL RADIOLOGY. 2002;57(3):211-218
MR Imaging and computed tomography in patients with rectal tumours clinically judged as locally advanced
Blomqvist L; Holm T; Nyrén S; Svanström R; Ulvskog Y; Iselius L
Article: CRITICAL CARE MEDICINE. 2001;29(5):959-964
High continuous positive airway pressure level induces ventilation/perfusion mismatch in the prone position
Mure M; Nyrén S; Jacobsson H; Larsson SA; Lindahl SGE
Article: JOURNAL OF APPLIED PHYSIOLOGY. 1999;86(4):1135-1141
Pulmonary perfusion is more uniform in the prone than in the supine position:: scintigraphy in healthy humans
Nyrén S; Mure M; Jacobsson H; Larsson SA; Lindahl SGE
Article: MAGNETIC RESONANCE IN MEDICINE. 1997;37(5):676-682
Different effects of exercise and edema on T-2 relaxation in skeletal muscle
PloutzSnyder LL; Nyren S; Cooper TG; Potchen EJ; Meyer RA
Article: ACTA DIABETOLOGICA. 1996;33(4):274-276
Pancreas size and insulin secretion: Lack of association in non-diabetic subjects
Nyren S; Blomqvist L; Efendic S; Grill V
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Corrigendum: BMC NEPHROLOGY. 2021;22(1):326
Negative effects of iodine-based contrast agent on renal function in patients with moderate reduced renal function hospitalized for COVID-19 (vol 22, 297, 2021)
Kistner A; Tamm C; Svensson AM; Beckman MO; Strand F; Skold M; Nyren S
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa1980
Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia (BPD)
Um-Bergstrom P; Hallberg J; Pourbazargan M; Berggren-Brostrom E; Ferrara G; Eriksson M; Nyren S; Lilja G; Linden A; Wheelock A; Melen E; Skold M
Review: ACTA ONCOLOGICA. 2017;56(10):1249-1257
Implementation of lung cancer CT screening in the Nordic countries
Pedersen JH; Sorensen JB; Saghir Z; Flotten O; Brustugun OT; Ashraf H; Strand T-E; Friesland S; Koyi H; Ek L; Nyren S; Bergman P; Jekunen A; Nieminen E-M; Gudbjartsson T
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2017;50:pa3647
Inflammatory cells in the parenchyma of the lungs with mild emphysema
Karimi R; Kotortsi I; Wheelock AM; Nyren S; Skold M
Review: LAKARTIDNINGEN. 2017;114:D93A
[Iatrogenic cerebral arterial gas embolism after lung biopsy].
Radecka E; Stjernqvist P; Nyren S; Nekludov M
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2013;71:343-344
LUNG CHANGES ARE PRESENT IN ACPA POSITIVE RA ALREADY AT DISEASE ONSET
Reynisdotirr G; Karimi R; Joshua V; Hensvold AH; Ossipova E; Ytterberg J; Nyren S; Harju A; Grunewald J; Lundberg K; Eklund A; Jakobson P-J; Zubarev R; Klareskog L; Skold M; Catrina AI
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2013;72:A2
EARLY SIGNS OF SUBCLINICAL INFLAMMATION AND LOCAL ANTIBODY PRODUCTION IN EARLY RHEUMATOID LUNGS
Reynisdottir G; Karimi R; Olsen H; Joshua V; Hensvold AH; Harju A; Engstrom M; Grunewald J; Nyren S; Eklund A; Klareskog L; Skold M; Catrina AI
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2012;71:A23
LUNG CHANGES DETECTED BY HIGH RESOLUTION TOMOGRAPHY ARE PRESENT IN ACPA POSITIVE RA PATIENTS ALREADY AT DISEASE ONSET
Reynisdottir G; Joshua V; Nyren S; Hensvold A; Karimi R; Harju A; Engstrom M; Skold M; Eklund A; Grunewald J; Klareskog L; Catrina AI
Letter: FERTILITY AND STERILITY. 2012;97(2):E6
Defining exercise prescription in lifestyle modification programs for overweight/obese polycystic ovary syndrome women REPLY
Nybacka A; Carlstrom K; Stahle A; Nyren S; Hellstrom P; Hirschberg AL
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A13
LUNG CHANGES ARE PRESENT IN ACPA POSITIVE RA PATIENTS ALREADY AT DISEASE ONSET
Reynsdottir G; Harju A; Engstrom M; Nyren S; Nyren S; Skold M; Eklund A; Grunewald J; Klareskog L; Catrina AI
Thesis / dissertation: 2010
The effects of posture, airway pressure and anesthesia on regulation of the regional ventilation and perfusion distribution in healthy humans
Nyrén, Sven
Meeting abstract: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2009;75(3):S608-S609
Fine-needle Marker for IGRT, a New Fiducial Gold Anchor for High-precision Radiotherapy
Naslund I; Wersall P; Castellanos E; Beskow C; Nyren S

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Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2022-2024

Degrees and Education

Docent, Karolinska Institutet, 2017
Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2010

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