Sven-Erik Dahlén

About me
Publications
CV
Public outreach and news

Research

Leukotrienes and prostanoids as mast cell mediators and modulators of asthmatic airway obstruction.

The aim of this project is to increase the understanding of mechanisms behind the development of asthma and other inflammatory airway diseases. Acknowledged internationally, our research group has over the years gathered experience and knowledge in leukotrienes, prostanoids and other inflammatory mediators. We have shown earlier that leukotrienes, together with histamine, cause some of the cardinal symptoms of asthma. The mechanisms through which leukotrienes exert their cellular effects are presently not well understood. Like leukotrienes, prostanoids are derived from the poly-unsaturated, essential fatty acid, arachidonic acid. The mechanisms and the location of prostanoid generation and effects differ importantly from those of the leukotrienes. The prostanoid family contains members that mediate asthma augmentation and airway inflammation. On the other hand, relief of asthma symptoms by other members of the family has also been described. Again, understanding how prostanoids mediate their cellular effects, particularly in the lung is presently only sketchily understood, at best. The main drive of this project is to elucidate the beneficial and malign mechanisms by which leukotrienes and prostanoids exert their effects on the different cellular structures of the lung. As this is very much and experimental undertaking, our set up consists of a network of co-operating basic researchers and clinicians and aims to provide comprehensive answers using animal models and human tissues. Implicit in our research is the aim for new discoveries which can lead to improved diagnosis and treatment of all airway inflammatory diseases, including asthma.

Financing
Swedish Research Council
Swedish Heart-Lung Foundation

Co-workers
Yvonne Nygren, secreterary
Mikael Adner, Associated Professor
Maria Kumlin, Associated Professor
Anita Sydbom, Associated Professor
Roelinde Middelveld, Project leader, PhD
Katarina Stark, Postdoc
Cecilia Kemi, Postdoc
Maciek Kupczyk, Postdoc
Ingrid Delin, BMA
Susanna Kumlien-Georén, BMA, PhD
Stina Gustavsson, assistant
Linda Swedin, PhD student
Jesper Säfholm, PhD student

Selected publications

Article: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS. 2008;78(2):89-97
Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung
Selg E; Lastbom L; Ryrfeldt A; Kumlin M; Dahlen S-E
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2007;152(8):1185-1195
Antagonism of thromboxane receptors by diclofenac and lumiracoxib
Selg E; Buccellati C; Andersson M; Rovati GE; Ezinga M; Sala A; Larsson A-K; Ambrosio E; Låstbom L; Capra V; Dahlen B; Ryrfeldt A; Folco GC; Dahlen S-E
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;119(5):1267-1268
Assessment of in vivo 5-lipoxygenase activity by analysis of leukotriene B₄ in saliva:: Effects of treatment with zileuton
Gaber F; James A; Delin I; Wetterholm A; Sampson AP; Dahlen B; Dahlen S-E; Kumlin M
Article: EUROPEAN RESPIRATORY JOURNAL. 2006;28(3):603-611
Characterisation of guinea pig precision-cut lung slices:: comparison with human tissues
Ressmeyer AR; Larsson AK; Vollmer E; Dahlen SE; Uhlig S; Martin C

Articles

Article: MUCOSAL IMMUNOLOGY. 2025;18(3):656-667
Female sex hormones and the oral contraceptive pill modulate asthma severity through GLUT-1
Brown AC; Carroll OR; Mayall JR; Zounemat-Kermani N; Vinzenz SLE; Gomez HM; Mills EF; Kim RY; Donovan C; Baines KJ; Williams EJ; Berthon BS; Wynne K; Scott HA; Pinkerton JW; Guo Y; Hansbro PM; Foster PS; Wark PAB; Dahlen S-E; Adcock IM; Wood LG; Horvat JC
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2025;155(4):1310-1320
Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
Alvarado-Vazquez PA; Mendez-Enriquez E; Salomonsson M; Kopac P; Koren A; Bidovec-Stojkovic U; Koren A; Bidovec-Stojkovic U; Skrgat S; Simonson OE; Yasinska V; Dahlen S-E; Pejler G; Janson C; Korosec P; Malinovschi A; Hallgren J
Article: EUROPEAN RESPIRATORY JOURNAL. 2025;65(3):2400691
Patient-centred composite scores as tools for assessment of response to biological therapy for paediatric and adult severe asthma
Khaleva E; Brightling C; Eiwegger T; Altraja A; Begin P; Blumchen K; Bossios A; Bourdin A; Ten Brinke A; Brusselle G; Bumbacea RS; Bush A; Casale TB; Clarke GW; Chaudhuri R; Chung KF; Coleman C; Corren J; Dahlen S-E; Deschildre A; Djukanovic R; Eger K; Exley A; Fleming L; Fowler SJ; Gaillard EA; Gappa M; Gupta A; Haitchi HM; Hashimoto S; Heaney LG; Hedlin G; Henderson M; Hua W; Jackson DJ; Karadag B; Katelaris CH; Koh MS; Kopp MV; Koppelman GH; Kull I; Kurukulaaratchy RJ; Lee J-H; Mahler V; Makela M; Masoli M; Mathioudakis AG; Mazon A; Melen E; Milger K; Moeller A; Murray CS; Nagakumar P; Nair P; Negus J; Nieto A; Papadopoulos NG; Paton J; Pijnenburg MW; Pike KC; Porsbjerg C; Rattu A; Rupani H; Rusconi F; Rutjes NW; Saglani S; Seddon P; Siddiqui S; Singer F; Tajiri T; Turner S; Upham JW; Vijverberg SJH; Wark PAB; Wechsler ME; Yasinska V; Roberts G
Article: LANCET RESPIRATORY MEDICINE. 2025;13(1):35-46
Development of an asthma health-care burden score as a measure of severity and predictor of remission in SARP III and U-BIOPRED: results from two major longitudinal asthma cohorts
Zein JG; Zounemat-Kerman N; Adcock IM; Hu B; Attaway A; Castro M; Dahlen S-E; Denlinger LC; Erzurum SC; Fahy JV; Gaston B; Hastie AT; Israel E; Jarjour NN; Levy BD; Mauger DT; Moore W; Peters MC; Sumino K; Townsend E; Woodruff P; Ortega VE; Wenzel SE; Meyers DA; Chung KF; Bleecker ER; Unbiased Biomarkers Prediction Respiratory Disease ER
Article: HEALTH AND QUALITY OF LIFE OUTCOMES. 2024;22(1):109
Clinical importance of patient-reported outcome measures in severe asthma: results from U-BIOPRED
Meys R; Franssen FME; Van 't Hul AJ; Bakke PS; Caruso M; Dahlen B; Fowler SJ; Geiser T; Howarth PH; Horvath I; Krug N; Behndig AF; Singer F; Musial J; Shaw DE; Montuschi P; Zee AHM-VD; Sterk PJ; Roberts G; Kermani NZ; Incalzi RA; Louis R; Andersson LI; Wagers SS; Dahlen S-E; Chung KF; Adcock IM; Spruit MA; U-BIOPRED SG
Article: EUROPEAN RESPIRATORY JOURNAL. 2024;64(5):2400207
Radiomultiomics: quantitative CT clusters of severe asthma associated with multiomics
Kermani NZ; Chung KF; Macis G; Santini G; Clemeno FAA; Versi A; Sun K; Abdel-Aziz MI; Andersson LI; Auffray C; Badi Y; Bakke P; Brightling C; Brinkman P; Caruso M; Chanez P; De Meulder B; Djukanovic R; Fabbri L; Fowler SJ; Horvath I; Howarth P; James AJ; Kolmert J; Kraft M; Li C-X; Zee AHM-VD; Malerba M; Papi A; Rabe K; Sanak M; Shaw DE; Singh D; Mikus MS; van den Berge M; Wheelock AM; Wheelock CE; Yasinska V; Guo Y-K; Wagers S; Barnes PJ; Bush A; Sterk PJ; Dahlen S-E; Adcock IM; Siddiqui S; Montuschi P
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2024;210(9):1091-1100
Exhaled Volatile Organic Compounds for Asthma Control Classification in Children with Moderate to Severe Asthma Results from the SysPharmPediA Study
Khamas SS; Van Dijk Y; Abdel-Aziz MI; Neerincx AH; Blankestijn JM; Vijverberg SJH; Hashimoto S; Bush A; Kraneveld AD; Hedman AM; Toncheva AA; Almqvist C; Wolff C; Murray CS; Hedlin G; Roberts G; Adcock IM; Korta-Murua J; Bonnelykke K; Fleming LJ; Pino-Yanes M; Gorenjak M; Kabesch M; Sardon-Prado O; Montuschi P; Singer F; Elosegui PC; Fowler SJ; Brandstetter S; Harner S; Dahlen S-E; Potocnik U; Frey U; van Aalderen W; Brinkman P; Maitland-van der Zee A-H; Consortia UBIOPRE
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2024;210(9):1101-1112
Discovery and Validation of a Volatile Signature of Eosinophilic Airway Inflammation in Asthma
Peltrini R; Cordell RL; Wilde M; Abuhelal S; Quek E; Zounemat-Kermani N; Ibrahim W; Richardson M; Brinkman P; Schleich F; Stefanuto P-H; Aung H; Greening N; Dahlen SE; Djukanovic R; Adcock IM; Brightling C; Monks P; Siddiqui S
Article: CLINICAL AND TRANSLATIONAL MEDICINE. 2024;14(9):e70007
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia
Versi A; Azim A; Ivan FX; Abdel-Aziz MI; Bates S; Riley J; Uddin M; Kermani NZ; Maitland-van der Zee A-H; Dahlen S-E; Djukanovic R; Chotirmall SH; Howarth P; Adcock IM; Chung KF
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2024;210(3):288-297
Biomarker Predictors of Clinical Efficacy of the Anti-IgE Biologic Omalizumab in Severe Asthma in Adults Results of the SoMOSA Study
Djukanovic R; Brinkman P; Kolmert J; Gomez C; Schofield J; Brandsma J; Shapanis A; Skipp PJS; Postle A; Wheelock C; Dahlen S-E; Sterk PJ; Brown T; Jackson DJ; Mansur A; Pavord I; Patel M; Brightling C; Siddiqui S; Bradding P; Sabroe I; Saralaya D; Chishimba L; Porter J; Robinson D; Fowler S; Howarth PH; Little L; Oliver T; Hill K; Stanton L; Allen A; Ellis D; Griffiths G; Harrison T; Akenroye A; Lasky-Su J; Heaney L; Chaudhuri R; Kurukulaaratchy R
Article: ALLERGY ASTHMA & IMMUNOLOGY RESEARCH. 2024;16(4):338-352
Comparison of Asthma Phenotypes in Severe Asthma Cohorts (SARP, U-BIOPRED, ProAR and COREA) From 4 Continents
Park S-Y; Fowler S; Shaw DE; Adcock IM; Sousa AR; Djukanovic R; Dahlen S-E; Sterk PJ; Kermani NZ; Calhoun W; Israel E; Castro M; Mauger D; Meyers D; Bleecker E; Moore W; Busse W; Jarjour N; Denlinger L; Levy B; Choi B-H; Kim S-H; Jang A-S; Lee T; Cho Y-J; Shin YS; Cho S-H; Won S; Cruz AA; Wenzel SE; Chung KF; Kim T-B
Article: CLINICAL AND TRANSLATIONAL MEDICINE. 2024;14(7):e1771
Endotypes of severe neutrophilic and eosinophilic asthma from multi-omics integration of U-BIOPRED sputum samples
Kermani NZ; Li C-X; Versi A; Badi Y; Sun K; Abdel-Aziz MI; Bonatti M; van der Zee A-H; Djukanovic R; Wheelock A; Dahlen S-E; Howarth P; Guo Y; Chung KF; Adcock IM
Article: PROSTAGLANDINS & OTHER LIPID MEDIATORS. 2024;170:106789
A single extraction 96-well method for LC-MS/MS quantification of urinary eicosanoids, steroids and drugs
Sieminska J; Kolmert J; Zurita J; Benkestock K; Revol-Cavalier J; Niklinski J; Reszec J; Dahlen S-E; Ciborowski M; Wheelock CE
Article: EBIOMEDICINE. 2024;99:104936
Proteomic signatures of eosinophilic and neutrophilic asthma from serum and sputum
Asamoah K; Chung KF; Kermani NZ; Bodinier B; Dahlen S-E; Djukanovic R; Bhavsar PK; Adcock IM; Vuckovic D; Chadeau-Hyam M
Article: ALLERGY. 2023;78(11):2906-2920
Haemophilus influenzae and Moraxella catarrhalis in sputum of severe asthma with inflammasome and neutrophil activation
Versi A; Ivan FX; Abdel-Aziz MI; Bates S; Riley J; Baribaud F; Kermani NZ; Montuschi P; Dahlen S-E; Djukanovic R; Sterk P; Maitland-Van Der Zee AH; Chotirmall SH; Howarth P; Adcock IM; Chung KF
Article: ERJ OPEN RESEARCH. 2023;9(5):00269-02023
Low levels of endogenous anabolic androgenic steroids in females with severe asthma taking corticosteroids
Yasinska V; Gomez C; Kolmert J; Ericsson M; Pohanka A; James A; Andersson LI; Sparreman-Mikus M; Sousa AR; Riley JH; Bates S; Bakke PS; Kermani NZ; Caruso M; Chanez P; Fowler SJ; Geiser T; Howarth PH; Horvath I; Krug N; Montuschi P; Sanak M; Behndig A; Shaw DE; Knowles RG; Dahlen B; Maitland-van der Zee A-H; Sterk PJ; Djukanovic R; Adcock IM; Chung KF; Wheelock CE; Dahlen S-E; Jonsson EW
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;152(1):117-125
Stratification of asthma by lipidomic profiling of induced sputum supernatant
Brandsma J; Schofield JPR; Yang X; Strazzeri F; Barber C; Goss VM; Koster G; Bakke PS; Caruso M; Chanez P; Dahlen S-E; Fowler SJ; Horvath I; Krug N; Montuschi P; Sanak M; Sandstrom T; Shaw DE; Chung KF; Singer F; Fleming LJ; Adcock IM; Pandis I; Bansal AT; Corfield J; Sousa AR; Sterk PJ; Sanchez-Garcia RJ; Skipp PJ; Postle AD; Djukanovic R
Article: BRAIN BEHAVIOR AND IMMUNITY. 2023;111:249-258
The role of inflammation in anxiety and depression in the European U-BIOPRED asthma cohorts
Hou R; Ye G; Cheng X; Shaw DE; Bakke PS; Caruso M; Dahlen B; Dahlen S-E; Fowler SJ; Horvath I; Howarth P; Krug N; Montuschi P; Sanak M; Sandstrom T; Auffray C; De Meulder B; Sousa AR; Adcock IM; Chung KF; Sterk PJ; Skipp PJ; Schofield J; Djukanovic R
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1151754
Analysis of human lung mast cells by single cell RNA sequencing
Ronnberg E; Ravindran A; Mazzurana L; Gong Y; Safholm J; Lorent J; Dethlefsen O; Orre A-C; Al-Ameri M; Adner M; Dahlen S-E; Dahlin JS; Mjosberg J; Nilsson G
Article: PLOS ONE. 2023;18(2):e0281356
A novel assay for improved detection of sputum periostin in patients with asthma
Ono J; Takai M; Kamei A; Ohta S; Nair P; Izuhara K; Dahlen S-E; James A
Article: LANCET RESPIRATORY MEDICINE. 2023;11(1):55-64
Predictors and associations of the persistent airflow limitation phenotype in asthma: a post-hoc analysis of the ATLANTIS study
Kole TM; Vanden Berghe E; Kraft M; Vonk JM; Nawijn MC; Siddiqui S; Sun K; Fabbri LM; Rabe KF; Chung KF; Nicolini G; Papi A; Brightling C; Singh D; van der Molen T; Dahlen S-E; Agusti A; Faner R; Wedzicha JA; Donaldson GC; Adcock IM; Lahousse L; Kerstjens HAM; van den Berge M
Article: ALLERGY. 2023;78(1):156-167
IL1RAP expression and the enrichment of IL-33 activation signatures in severe neutrophilic asthma
Badi YE; Salcman B; Taylor A; Rana B; Kermani NZ; Riley JH; Worsley S; Mumby S; Dahlen S-E; Cousins D; Silvia B-P; Affleck K; Chung KF; Bates S; Adcock IM
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2022;934:175257
Cysteinyl-maresin 3 inhibits IL-13 induced airway hyperresponsiveness through alternative activation of the CysLT1 receptor
Safholm J; Abma W; Bankova LG; Boyce JA; Al-Ameri M; Orre A-C; Wheelock CE; Dahlen S-E; Adner M
Article: ALLERGY. 2022;77(9):2677-2687
Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction
Tang X; Ronnberg E; Safholm J; Thulasingam M; Trauelsen M; Schwartz TW; Wheelock CE; Dahlen S-E; Nilsson G; Haeggstrom JZ
Article: ALLERGY. 2022;77(8):2337-2354
Effects of non-steroidal anti-inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses: EAACI task force on eicosanoids consensus report in times of COVID-19
Sokolowska M; Rovati GE; Diamant Z; Untersmayr E; Schwarze J; Lukasik Z; Sava F; Angelina A; Palomares O; Akdis C; O'Mahony L; Jesenak M; Pfaar O; Torres MJ; Sanak M; Dahlen S-E; Woszczek G
Article: CLINICAL PROTEOMICS. 2022;19(1):20
A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways
Ostling J; Van Geest M; Olsson HK; Dahlen S-E; Viklund E; Gustafsson PM; Mirgorodskaya E; Olin A-C
Article: EUROPEAN RESPIRATORY JOURNAL. 2022;59(6):2101733
Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study
Reinke SN; Naz S; Chaleckis R; Gallart-Ayala H; Kolmert J; Kermani NZ; Tiotiu A; Broadhurst DI; Lundqvist A; Olsson H; Strom M; Wheelock AM; Gomez C; Ericsson M; Sousa AR; Riley JH; Bates S; Scholfield J; Loza M; Baribaud F; Bakke PS; Caruso M; Chanez P; Fowler SJ; Geiser T; Howarth P; Horvath I; Krug N; Montuschi P; Behndig A; Singer F; Musial J; Shaw DE; Dahlen B; Hu S; Lasky-Su J; Sterk PJ; Chung KF; Djukanovic R; Dahlen S-E; Adcock IM; Wheelock CE
Article: CLINICAL AND TRANSLATIONAL MEDICINE. 2022;12(4):e816
Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort
Hoda U; Pavlidis S; Bansal AT; Takahashi K; Hu S; Ng Kee Kwong F; Rossios C; Sun K; Bhavsar P; Loza M; Baribaud F; Chanez P; Fowler SJ; Horvath I; Montuschi P; Singer F; Musial J; Dahlen B; Krug N; Sandstrom T; Shaw DE; Lutter R; Fleming LJ; Howarth PH; Caruso M; Sousa AR; Corfield J; Auffray C; De Meulder B; Lefaudeux D; Dahlen S-E; Djukanovic R; Sterk PJ; Guo Y; Adcock IM; Chung KF
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;205(4):397-411
Association of Differential Mast Cell Activation with Granulocytic Inflammation in Severe Asthma
Tiotiu A; Badi Y; Kermani NZ; Sanak M; Kolmert J; Wheelock CE; Hansbro PM; Dahlen S-E; Sterk PJ; Djukanovic R; Guo Y; Mumby S; Adcock IM; Chung KF
Article: EUROPEAN RESPIRATORY JOURNAL. 2022;59(2):2100142
Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation
Mikus MS; Kolmert J; Andersson LI; Ostling J; Knowles RG; Gomez C; Ericsson M; Thorngren J-O; Khoonsari PE; Dahlen B; Kupczyk M; De Meulder B; Auffray C; Bakke PS; Beghe B; Bel EH; Caruso M; Chanez P; Chawes B; Fowler SJ; Gaga M; Geiser T; Gjomarkaj M; Horvath I; Howarth PH; Johnston SL; Joos G; Krug N; Montuschi P; Musial J; Nizankowska-Mogilnicka E; Olsson HK; Papi A; Rabe KF; Sandstrom T; Shaw DE; Siafakas NM; Uhlen M; Riley JH; Bates S; Middelveld RJM; Wheelock CE; Chung KF; Adcock IM; Sterk PJ; Djukanovic R; Nilsson P; Dahlen S-E; James A
Article: FRONTIERS IN IMMUNOLOGY. 2022;12:804812
Immunoprofiling Reveals Novel Mast Cell Receptors and the Continuous Nature of Human Lung Mast Cell Heterogeneity
Ronnberg E; Boey DZH; Ravindran A; Safholm J; Orre A-C; Al-Ameri M; Adner M; Dahlen S-E; Dahlin JS; Nilsson G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(1):89-101
Mapping atopic dermatitis and anti-IL-22 response signatures to type 2-low severe neutrophilic asthma
Badi YE; Pavel AB; Pavlidis S; Riley JH; Bates S; Kermani NZ; Knowles R; Kolmert J; Wheelock CE; Worsley S; Uddin M; Alving K; Bakke PS; Behndig A; Caruso M; Chanez P; Fleming LJ; Fowler SJ; Frey U; Howarth P; Horvath I; Krug N; Maitland-van der Zee AH; Montuschi P; Roberts G; Sanak M; Shaw DE; Singer F; Sterk PJ; Djukanovic R; Dahlen S-E; Guo Y-K; Chung KF; Guttman-Yassky E; Adcock IM
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2021;907:174282
Prostaglandin D₂ inhibits mediator release and antigen induced bronchoconstriction in the Guinea pig trachea by activation of DP₁ receptors
Safholm J; Abma W; Liu J; Balgoma D; Fauland A; Kolmert J; Wheelock CE; Adner M; Dahlen S-E
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;148(3):889-894
Distinct plasma biomarkers confirm the diagnosis of mastocytosis and identify increased risk of anaphylaxis
Gulen T; Teufelberger A; Ekoff M; Westerberg CM; Lyberg K; Dahlen S-E; Dahlen B; Nilsson G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;148(2):407-419
Lung function fluctuation patterns unveil asthma and COPD phenotypes unrelated to type 2 inflammation
Delgado-Eckert E; James A; Meier-Girard D; Kupczyk M; Andersson LI; Bossios A; Mikus M; Ono J; Izuhara K; Middelveld R; Dahlen B; Gaga M; Siafakas NM; Papi A; Beghe B; Joos G; Rabe KF; Sterk PJ; Bel EH; Johnston SL; Chanez P; Gjomarkaj M; Howarth PH; Nizankowska-Mogilnicka E; Dahlen S-E; Frey U
Article: CHEST. 2021;160(1):53-64
Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort
Alahmadi FH; Simpson AJ; Gomez C; Ericsson M; Thorngren J-O; Wheelock CE; Shaw DE; Fleming LJ; Roberts G; Riley J; Bates S; Sousa AR; Knowles R; Bansal AT; Corfield J; Pandis I; Sun K; Bakke PS; Caruso M; Chanez P; Dahlen B; Horvath I; Krug N; Montuschi P; Singer F; Wagers S; Adcock IM; Djukanovic R; Chung KF; Sterk PJ; Dahlen S-E; Fowler SJ
Article: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2021;1866(5):158886
COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells
Johnsson A-K; Ronnberg E; Fuchs D; Kolmert J; Safholm J; Claesson H-E; Hamberg M; Wheelock CE; Nilsson G; Dahlen S-E
Article: CELL RESEARCH. 2021;31(5):554-568
Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing
Mazzurana L; Czarnewski P; Jonsson V; Wigge L; Ringner M; Williams TC; Ravindran A; Bjorklund AK; Safholm J; Nilsson G; Dahlen S-E; Orre A-C; Al-Ameri M; Hoog C; Hedin C; Szczegielniak S; Almer S; Mjosberg J
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2021;51(4):594-603
Selective inhibition of prostaglandin D₂ biosynthesis in human mast cells to overcome need for multiple receptor antagonists: Biochemical consequences
Johnsson A-K; Choi J-H; Ronnberg E; Fuchs D; Kolmert J; Hamberg M; Dahlen B; Wheelock CE; Dahlen S-E; Nilsson G
Article: RESPIRATORY RESEARCH. 2021;22(1):10
Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma
Kermani NZ; Song W-J; Badi Y; Versi A; Guo Y; Sun K; Bhavsar P; Howarth P; Dahlen S-E; Sterk PJ; Djukanovic R; Adcock IM; Chung KF
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(1):123-134
Sputum microbiome profiles identify severe asthma phenotypes of relative stability at 12 to 18 months
Abdel-Aziz MI; Brinkman P; Vijverberg SJH; Neerincx AH; Riley JH; Bates S; Hashimoto S; Kermani NZ; Chung KF; Djukanovic R; Dahlen S-E; Adcock IM; Howarth PH; Sterk PJ; Kraneveld AD; Maitland-van der Zee AH
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2021;203(1):37-53
Urinary Leukotriene E₄ and Prostaglandin D₂ Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation A Clinical Observational Study
Kolmert J; Gomez C; Balgoma D; Sjodin M; Bood J; Konradsen JR; Ericsson M; Thorngren J-O; James A; Mikus M; Sousa AR; Riley JH; Bates S; Bakke PS; Pandis I; Caruso M; Chanez P; Fowler SJ; Geiser T; Howarth P; Horvath I; Krug N; Montuschi P; Sanak M; Behndig A; Shaw DE; Knowles RG; Holweg CTJ; Wheelock AM; Dahlen B; Nordlund B; Alving K; Hedlin G; Chung KF; Adcock IM; Sterk PJ; Djukanovic R; Dahlen S-E; Wheelock CE
Article: ALLERGY. 2021;76(1):114-130
Current perspective on eicosanoids in asthma and allergic diseases: EAACI Task Force consensus report, part I
Sokolowska M; Rovati GE; Diamant Z; Untersmayr E; Schwarze J; Lukasik Z; Sava F; Angelina A; Palomares O; Akdis CA; O'Mahony L; Sanak M; Dahlen S-E; Woszczek G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;146(5):1045-1055
eNose breath prints as a surrogate biomarker for classifying patients with asthma by atopy
Abdel-Aziz MI; Brinkman P; Vijverberg SJH; Neerincx AH; de Vries R; Dagelet YWF; Riley JH; Hashimoto S; Montuschi P; Chung KF; Djukanovic R; Fleming LJ; Murray CS; Frey U; Bush A; Singer F; Hedlin G; Roberts G; Dahlen S-E; Adcock IM; Fowler SJ; Knipping K; Sterk PJ; Kraneveld AD; Maitland-van Der Zee AH
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2020;50(10):1184-1195
A new house dust mite-driven and mast cell-activated model of asthma in the guinea pig
Ramos-Ramirez P; Noreby M; Liu J; Ji J; Abdillahi SM; Olsson H; Dahlen S-E; Nilsson G; Adner M
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Lipoxin A₄ reduces house dust mite and TNFα-induced hyperreactivity in the mouse trachea
Abma W; Noreby M; Wheelock CE; Dahlen S-E; Adner M; Safholm J
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Eosinophils synthesize trihydroxyoctadecenoic acids (TriHOMEs) via a 15-lipoxygenase dependent process
Fuchs D; Tang X; Johnsson A-K; Dahlen S-E; Hamberg M; Wheelock CE
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;145(3):808-817.e2
IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways
Manson ML; Safholm J; James A; Johnsson A-K; Bergman P; Al-Ameri M; Orre A-C; Karrman-Mardh C; Dahlen S-E; Adner M
Article: EUROPEAN RESPIRATORY JOURNAL. 2020;55(2):1900544
Exhaled volatile organic compounds as markers for medication use in asthma
Brinkman P; Ahmed WM; Gomez C; Knobel HH; Weda H; Vink TJ; Nijsen TM; Wheelock CE; Dahlen S-E; Montuschi P; Knowles RG; Vijverberg SJ; Maitland-van der Zee AH; Sterk PJ; Fowler SJ
Article: EUROPEAN RESPIRATORY JOURNAL. 2020;55(1):1901163
Characteristics and treatment regimens across ERS SHARP severe asthma registries
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IL-17-high asthma with features of a psoriasis immunophenotype
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Article: ALLERGY. 2019;74(10):1835-1851
Toward clinically applicable biomarkers for asthma: An EAACI position paper
Diamant Z; Vijverberg S; Alving K; Bakirtas A; Bjermer L; Custovic A; Dahlen S-E; Gaga M; van Wijk RG; Del Giacco S; Hamelmann E; Heaney LG; Heffler E; Kalayci O; Kostikas K; Lutter R; Olin A-C; Sergejeva S; Simpson A; Sterk PJ; Tufvesson E; Agache I; Seys SF
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(4):984-992
Mannitol triggers mast cell-dependent contractions of human small bronchi and prostacyclin bronchoprotection
Safholm J; Manson ML; Bood J; Al-Ameri M; Orre A-C; Raud J; Dahlen S-E; Adner M
Article: ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY. 2019;15(1):54
Food allergy-related concerns during the transition to self-management
Protudjer JLP; Middelveld R; Dahlen S-E; Ahlstedt S
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(1):70-82
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Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1361
Divergent Effects of Acute and Prolonged Interleukin 33 Exposure on Mast Cell IgE-Mediated Functions
Ronnberg E; Ghaib A; Ceriol C; Enoksson M; Arock M; Safholm J; Orre A-C; Al-Ameri M; Adner M; Dahlen S-E; Ekoff M; Nilsson G
Article: JOURNAL OF LIPID RESEARCH. 2019;60(6):1164-1173
Quantitative metabolic profiling of urinary eicosanoids for clinical phenotyping
Gomez C; Gonzalez-Riano C; Barbas C; Kolmert J; Ryu MH; Carlsten C; Dahlen S-E; Wheelock CE
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(6):2202-2214.e5
Cytokine-induced endogenous production of prostaglandin D₂ is essential for human group 2 innate lymphoid cell activation
Maric J; Ravindran A; Mazzurana L; Van Acker A; Rao A; Kokkinou E; Ekoff M; Thomas D; Fauland A; Nilsson G; Wheelock CE; Dahlen S-E; Ferreiros N; Geisslinger G; Friberg D; Heinemann A; Konya V; Mjosberg J
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(5):1811-1820.e7
Identification and prospective stability of electronic nose (eNose)-derived inflammatory phenotypes in patients with severe asthma
Brinkman P; Wagener AH; Hekking P-P; Bansal AT; Maitland-van der Zee A-H; Wang Y; Weda H; Knobel HH; Vink TJ; Rattray NJ; D'Amico A; Pennazza G; Santonico M; Lefaudeux D; De Meulder B; Auffray C; Bakke PS; Caruso M; Chanez P; Chung KF; Corfield J; Dahlen S-E; Djukanovic R; Geiser T; Horvath I; Krug N; Musial J; Sun K; Riley JH; Shaw DE; Sandstrom T; Sousa AR; Montuschi P; Fowler SJ; Sterk PJ
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2019;49(4):442-460
Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study
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Fixed airflow obstruction relates to eosinophil activation in asthmatics
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Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis: a cross-sectional study
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Article: FRONTIERS IN IMMUNOLOGY. 2018;9:2193
An Optimized Protocol for the Isolation and Functional Analysis of Human Lung Mast Cells
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Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;142(4):1080-1089
Leukotriene E₄ induces airflow obstruction and mast cell activation through the cysteinyl leukotriene type 1 receptor
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Article: PLOS ONE. 2018;13(9):e0203874
Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort
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Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers
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Lipid Mediator Quantification in Isolated Human and Guinea Pig Airways: An Expanded Approach for Respiratory Research
Kolmert J; Fauland A; Fuchs D; Safholm J; Gomez C; Adner M; Dahlen S-E; Wheelock CE
Article: PROSTAGLANDINS & OTHER LIPID MEDIATORS. 2018;137:20-29
Prominent release of lipoxygenase generated mediators in a murine house dust mite-induced asthma model
Kolmert J; Pineiro-Hermida S; Hamberg M; Gregory JA; Lopez IP; Fauland A; Wheelock CE; Dahlen S-E; Pichel JG; Adner M
Article: JOURNAL OF PROTEOME RESEARCH. 2018;17(6):2072-2091
Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome
Burg D; Schofield JPR; Brandsma J; Staykova D; Folisi C; Bansal A; Nicholas B; Xian Y; Rowe A; Corfield J; Wilson S; Ward J; Lutter R; Fleming L; Shaw DE; Bakke PS; Caruso M; Dahlen S-E; Fowler SJ; Hashimoto S; Horvath I; Howarth P; Krug N; Montuschi P; Sanak M; Sandstrom T; Singer F; Sun K; Pandis I; Auffray C; Sousa AR; Adcock IM; Chung KF; Sterk PJ; Djukanovic R; Skipp PJ
Article: EUROPEAN RESPIRATORY JOURNAL. 2018;51(5):1702173
Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis
Takahashi K; Pavlidis S; Kwong FNK; Hoda U; Rossios C; Sun K; Loza M; Baribaud F; Chanez P; Fowler SJ; Horvath I; Montuschi P; Singer F; Musial J; Dahlen B; Dahlen S-E; Krug N; Sandstrom T; Shaw DE; Lutter R; Bakke P; Fleming LJ; Howarth PH; Caruso M; Sousa AR; Corfield J; Auffray C; De Meulder B; Lefaudeux D; Djukanovic R; Sterk PJ; Guo Y; Adcock IM; Chung KF
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;141(5):1761-1773.e6
Prostaglandin E₂ suppresses human group 2 innate lymphoid cell function
Maric J; Ravindran A; Mazzurana L; Bjorklund AK; Van Acker A; Rao A; Friberg D; Dahlen S-E; Heinemann A; Konya V; Mjosberg J
Article: THORAX. 2018;73(2):107-115
Functional phenotypes determined by fluctuation-based clustering of lung function measurements in healthy and asthmatic cohort participants
Delgado-Eckert E; Fuchs O; Kumar N; Pekkanen J; Dalphin J-C; Riedler J; Lauener R; Kabesch M; Kupczyk M; Dahlen S-E; von Mutius E; Frey U
Article: ALLERGY. 2017;72(11):1753-1760
Serum periostin relates to type-2 inflammation and lung function in asthma: Data from the large population-based cohort Swedish GA(2)LEN
James A; Janson C; Malinovschi A; Holweg C; Alving K; Ono J; Ohta S; Ek A; Middelveld R; Dahlen B; Forsberg B; Izuhara K; Dahlen S-E
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2017;47(7):909-917
Assessment of in vivo mast cell reactivity in patients with systemic mastocytosis
Gulen T; Westerberg CM; Lyberg K; Ekoff M; Kolmert J; Bood J; Ohd J; James A; Dahlen S-E; Nilsson G; Dahlen B
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(6):1797-1807
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics
Lefaudeux D; De Meulder B; Loza MJ; Peffer N; Rowe A; Baribaud F; Bansal AT; Lutter R; Sousa AR; Corfield J; Pandis I; Bakke PS; Caruso M; Chanez P; Dahlen S-E; Fleming LJ; Fowler SJ; Horvath I; Krug N; Montuschi P; Sanak M; Sandstrom T; Shaw DE; Singer F; Sterk PJ; Roberts G; Adcock IM; Djukanovic R; Auffray C; Chung KF
Article: EUROPEAN RESPIRATORY JOURNAL. 2017;49(5):1602294
Asthma research in Europe: a transformative agenda for innovation and competitiveness
Papadopoulos NG; Androutsopoulou A; Akdis C; Dahlen S-E; Djukanovic R; Edwards J; Garcia-Marcos L; Johnston SL; Kupczyk M; Martin TR; Myles D; Palkonen S; Powell P; Riley J; Walker S
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(4):1321-1330.e4
Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69^-CD56^dim cells
Marquardt N; Kekalainen E; Chen P; Kvedaraite E; Wilson JN; Ivarsson MA; Mjosberg J; Berglin L; Safholm J; Manson ML; Adner M; Al-Ameri M; Bergman P; Orre A-C; Svensson M; Dahlen B; Dahlen S-E; Ljunggren H-G; Michaelsson J
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2017;195(4):443-455
A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED
Kuo C-HS; Pavlidis S; Loza M; Baribaud F; Rowe A; Pandis I; Hoda U; Rossios C; Souse A; Wilson SJ; Howarth P; Dahlen B; Dahlen S-E; Chanez P; Shaw D; Krug N; Sandstrom T; De Meulder B; Lefaudeux D; Fowler S; Fleming L; Corfield J; Auffray C; Sterk PJ; Djukanovic R; Guo Y; Adcock IM; Chung KF
Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2017;28(1):79-85
A longitudinal assessment of circulating YKL-40 levels in preschool children with wheeze
James A; Hammar KS; Reinius L; Konradsen JR; Dahlen S-E; Soderhall C; Hedlin G
Article: JOURNAL OF NUTRITION HEALTH & AGING. 2017;21(1):92-104
BUILDING BRIDGES FOR INNOVATION IN AGEING: SYNERGIES BETWEEN ACTION GROUPS OF THE EIP ON AHA
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Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2016;46(12):1540-1548
Simultaneously elevated exhaled nitric oxide and serum-eosinophil cationic protein relate to recent asthma events in asthmatics in a cross-sectional population-based study
Mogensen I; Alving K; Bjerg A; Borres MP; Hedlin G; Sommar J; Dahlen S-E; Janson C; Malinovschi A
Article: ALLERGY. 2016;71(11):1603-1611
Respiratory hypersensitivity reactions to NSAIDs in Europe: the global allergy and asthma network (GA²LEN) survey
Makowska JS; Burney P; Jarvis D; Keil T; Tomassen P; Bislimovska J; Brozek G; Bachert C; Baelum J; Bindslev-Jensen C; Bousquet J; Bousquet PJ; Kai-Hakon C; Dahlen SE; Dahlen B; Fokkens WJ; Forsberg B; Gjomarkaj M; Howarth P; Salagean E; Janson C; Kasper L; Kraemer U; Louiro C; Lundback B; Minov J; Nizankowska-Mogilnicka E; Papadopoulos N; Sakellariou AG; Todo-Bom A; Toskala E; Zejda JE; Zuberbier T; Kowalski ML
Article: CLINICAL AND TRANSLATIONAL ALLERGY. 2016;6:37
Impaired health-related quality of life in adolescents with allergy to staple foods
Protudjer JLP; Jansson S-A; Middelveld R; Ostblom E; Dahlen S-E; Arnlind MH; Bengtsson U; Kallstrom-Bengtsson I; Marklund B; Rentzos G; Sundqvist A-C; Akerstrom J; Ahlstedt S
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2016;46(9):1185-1193
Important non-disease-related determinants of exhaled nitric oxide levels in mild asthma - results from the Swedish GA²LEN study
Al-Shamkhi N; Alving K; Dahlen SE; Hedlin G; Middelveld R; Bjerg A; Ekerljung L; Olin AC; Sommar J; Forsberg B; Janson C; Malinovschi A
Article: EUROPEAN RESPIRATORY JOURNAL. 2016;47(6):1645-1656
Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD
Balgoma D; Yang M; Sjodin M; Snowden S; Karimi R; Levanen B; Merikallio H; Kaarteenaho R; Palmberg L; Larsson K; Erle DJ; Dahlen S-E; Dahlen B; Skold CM; Wheelock AM; Wheelock CE
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2016;120(9):1011-1017
A standard, single dose of inhaled terbutaline attenuates hyperpnea-induced bronchoconstriction and mast cell activation in athletes
Simpson AJ; Bood JR; Anderson SD; Romer LM; Dahlen B; Dahlen S-E; Kippelen P
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2016;137(3):833-843
Activated prostaglandin D₂ receptors on macrophages enhance neutrophil recruitment into the lung
Jandl K; Stacher E; Balint Z; Sturm EM; Maric J; Peinhaupt M; Luschnig P; Aringer I; Fauland A; Konya V; Dahlen S-E; Wheelock CE; Kratky D; Olschewski A; Marsche G; Schuligoi R; Heinemann A
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193(2):131-142
Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease
James AJ; Reinius LE; Verhoek M; Gomes A; Kupczyk M; Hammar U; Ono J; Ohta S; Izuhara K; Bel E; Kere J; Soderhall C; Dahlen B; Boot RG; Dahlen S-E
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2016;170(1):57-61
Selective COX-2 Inhibition Exerts No Negative Effects on Peripheral Blood Lymphocytes in Allergic Asthmatics
Gafvelin G; Grundstrom J; Grimheden ME; Vidaurre SS; Daham K; Dahlen S-E; Dahlen B; van Hage M
Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2015;26(8):772-779
Predicting asthma morbidity in children using proposed markers of Th2-type inflammation
Konradsen JR; Skantz E; Nordlund B; Lidegran M; James A; Ono J; Ohta S; Izuhara K; Dahlen S-E; Alving K; Hedlin G
Article: ALLERGY. 2015;70(11):1372-1392
MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation
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Article: EUROPEAN RESPIRATORY JOURNAL. 2015;46(5):1308-1321
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
Shaw DE; Sousa AR; Fowler SJ; Fleming LJ; Roberts G; Corfield J; Pandis I; Bansal AT; Bel EH; Auffray C; Compton CH; Bisgaard H; Bucchioni E; Caruso M; Chanez P; Dahlen B; Dahlen S-E; Dyson K; Frey U; Geiser T; de Verdier MG; Gibeon D; Guo Y-K; Hashimoto S; Hedlin G; Jeyasingham E; Hekking P-PW; Higenbottam T; Horvath I; Knox AJ; Krug N; Erpenbeck VJ; Larsson LX; Lazarinis N; Matthews JG; Middelveld R; Montuschi P; Musial J; Myles D; Pahus L; Sandstrom T; Seibold W; Singer F; Strandberg K; Vestbo J; Vissing N; von Garnier C; Adcock IM; Wagers S; Rowe A; Howarth P; Wagener AH; Djukanovic R; Sterk PJ; Chung KF
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;136(5):1232-9.e1
Prostaglandin E₂ inhibits mast cell-dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor
Safholm J; Manson ML; Bood J; Delin I; Orre A-C; Bergman P; Al-Ameri M; Dahlen S-E; Adner M
Article: RESPIRATORY RESEARCH. 2015;16:129
TNFα-blockade stabilizes local airway hyperresponsiveness during TLR-induced exacerbations in murine model of asthma
Starkhammar M; Georen SK; Dahlen S-E; Cardell L-O; Adner M
Article: ACTA PAEDIATRICA. 2015;104(10):1047-1054
Health-related quality of life in children with objectively diagnosed staple food allergy assessed with a disease-specific questionnaire
Protudjer JLP; Jansson S-A; Ostblom E; Arnlind MH; Bengtsson U; Dahlen S-E; Kallstrom-Bengtsson I; Marklund B; Middelveld RJM; Rentzos G; Sundqvist AC; Akerstrom J; Ahlstedt S
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2015;119(3):272-279
Urinary excretion of lipid mediators in response to repeated eucapnic voluntary hyperpnea in asthmatic subjects
Bood JR; Sundblad B-M; Delin I; Sjodin M; Larsson K; Anderson SD; Wheelock CE; Dahlen S-E; Dahlen B
Article: THORAX. 2015;70(7):695-697
Human tissue models for a human disease: what are the barriers?
Edwards J; Belvisi M; Dahlen S-E; Holgate S; Holmes A
Article: ALLERGY. 2015;70(5):514-521
Interleukin-33 exacerbates allergic bronchoconstriction in the mice via activation of mast cells
Sjoberg LC; Gregory JA; Dahlen S-E; Nilsson GP; Adner M
Article: RESPIRATORY MEDICINE. 2015;109(3):312-319
The association between asthma and rhinitis is stable over time despite diverging trends in prevalence
Bjerg A; Eriksson J; Olafsdottir IS; Middelveld R; Franklin K; Forsberg B; Larsson K; Toren K; Dahlen S-E; Janson C
Article: CHEST. 2015;147(2):397-405
The Effect of Omega-3 Fatty Acids on Bronchial Hyperresponsiveness, Sputum Eosinophilia, and Mast Cell Mediators in Asthma
Brannan JD; Bood J; Alkhabaz A; Balgoma D; Otis J; Delin I; Dahlen B; Wheelock CE; Nair P; Dahlen S-E; O'Byrne PM
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2015;3(1):68-75
Household Costs Associated with Objectively Diagnosed Allergy to Staple Foods in Children and Adolescents
Protudjer JLP; Jansson S-A; Arnlind MH; Bengtsson U; Kallstrom-Bengtsson I; Marklund B; Middelveld R; Rentzos G; Sundqvist A-C; Akerstrom J; Ostblom E; Dahlen S-E; Ahlstedt S
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2014;740:302-311
Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle
Manson ML; Safholm J; Al-Ameri M; Bergman P; Orre A-C; Sward K; James A; Dahlen S-E; Adner M
Article: ALLERGY. 2014;69(9):1198-1204
Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma
Kupczyk M; Dahlen B; Sterk PJ; Nizankowska-Mogilnicka E; Papi A; Bel EH; Chanez P; Howarth PH; Holgate ST; Brusselle G; Siafakas NM; Gjomarkaj M; Dahlen S-E
Article: ALLERGY. 2014;69(9):1241-1247
Socioeconomic evaluation of well-characterized allergy to staple foods in adults
Jansson S-A; Protudjer JLP; Heibert MA; Bengtsson U; Kallstrom-Bengtsson I; Marklund B; Middelveld RJM; Rentzos G; Sundqvist AC; Akerstrom J; Ostblom E; Dahlen S-E; Ahlstedt S
Article: ALLERGY. 2014;69(9):1205-1214
The relation of airway obstruction to asthma, chronic rhinosinusitis and age: results from a population survey of adults
Obaseki D; Potts J; Joos G; Baelum J; Haahtela T; Ahlstrom M; Matricardi P; Kramer U; Gjomarkaj M; Fokkens W; Makowska J; Todo-Bom A; Toren K; Janson C; Dahlen S-E; Forsberg B; Jarvis D; Howarth P; Brozek G; Minov J; Bachert C; Burney P
Article: PLOS ONE. 2014;9(8):e104114
Toll-Like Receptor Ligands LPS and Poly (I:C) Exacerbate Airway Hyperresponsiveness in a Model of Airway Allergy in Mice, Independently of Inflammation
Starkhammar M; Larsson O; Georen SK; Leino M; Dahlen S-E; Adner M; Cardell L-O
Article: EUROPEAN RESPIRATORY JOURNAL. 2014;44(2):304-323
Integrated care pathways for airway diseases (AIRWAYS-ICPs)
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Effects of selective COX-2 inhibition on allergen-induced bronchoconstriction and airway inflammation in asthma
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Article: EUROPEAN RESPIRATORY JOURNAL. 2014;43(2):343-373
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
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Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2014;44(2):250-260
The association of asthma, nasal allergies, and positive skin prick tests with obesity, leptin, and adiponectin
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Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2014;44(2):212-221
Frequent exacerbators - a distinct phenotype of severe asthma
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Article: PEPTIDES. 2014;51:100-109
Enhanced expression of neuropeptide S (NPS) receptor in eosinophils from severe asthmatics and subjects with total IgE above 100 IU/ml
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Article: CLINICAL SCIENCE. 2013;125(11-12):533-542
Mast cell mediators cause early allergic bronchoconstriction in guinea-pigs in vivo: a model of relevance to asthma
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Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;718(1-3):544-551
Toll-like receptor (TLR) 7 decreases and TLR9 increases the airway responses in mice with established allergic inflammation
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Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;718(1-3):277-282
Antagonising EP₁ and EP2 receptors reveal that the TP receptor mediates a component of antigen-induced contraction of the guinea pig trachea
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Article: ALLERGY. 2013;68(10):1314-1321
Chronic rhinosinusitis in asthma is a negative predictor of quality of life: results from the Swedish GA²LEN survey
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Phenotypic predictors of response to oral glucocorticosteroids in severe asthma
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Article: BMJ OPEN RESPIRATORY RESEARCH. 2013;1(1):e000039
Quality of life in relation to the traffic pollution indicators NO₂ and NO_x: results from the Swedish GA²LEN survey
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Article: ANALYTICAL CHEMISTRY. 2013;85(16):7866-7874
Quantification of Lipid Mediator Metabolites in Human Urine from Asthma Patients by Electrospray Ionization Mass Spectrometry: Controlling Matrix Effects
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Article: MOLECULAR NUTRITION & FOOD RESEARCH. 2013;57(8):1378-1389
Lipid mediator serum profiles in asthmatics significantly shift following dietary supplementation with omega-3 fatty acids
Lundstrom SL; Yang J; Brannan JD; Haeggstrom JZ; Hammock BD; Nair P; O'Byrne P; Dahlen S-E; Wheelock CE
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;132(2):328-35.e5
The chitinase-like protein YKL-40: A possible biomarker of inflammation and airway remodeling in severe pediatric asthma
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Article: EUROPEAN RESPIRATORY JOURNAL. 2013;42(1):65-78
Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics
Orsmark-Pietrast C; James A; Konradsen JR; Nordlund B; Soderhall C; Pulkkinen V; Pedroletti C; Daham K; Kupczyk M; Dahlen B; Kere J; Dahlen S-E; Hedlin G; Melen E
Article: THORAX. 2013;68(7):611-618
Detection of exacerbations in asthma based on electronic diary data: results from the 1-year prospective BIOAIR study
Kupczyk M; Haque S; Sterk PJ; Nizankowska-Mogilnicka E; Papi A; Bel EH; Chanez P; Dahlen B; Gaga M; Gjomarkaj M; Howarth PH; Johnston SL; Joos GF; Kanniess F; Tzortzaki E; James A; Middelveld RJM; Dahlen S-E
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2013;168(4):794-806
PGE₂ maintains the tone of the guinea pig trachea through a balance between activation of contractile EP₁ receptors and relaxant EP₂ receptors
Safholm J; Dahlen S-E; Delin I; Maxey K; Stark K; Cardell L-O; Adner M
Article: PLOS ONE. 2013;8(1):e54137
Higher Risk of Wheeze in Female than Male Smokers. Results from the Swedish GA²LEN Study
Bjerg A; Ekerljung L; Eriksson J; Olafsdottir IS; Middelveld R; Franklin KA; Forsberg B; Larsson K; Lotvall J; Toren K; Dahlen S-E; Lundback B; Janson C
Article: PLOS ONE. 2013;8(1):e53877
DNA Methylation in the Neuropeptide S Receptor 1 (NPSR1) Promoter in Relation to Asthma and Environmental Factors
Reinius LE; Gref A; Saaf A; Acevedo N; Joerink M; Kupczyk M; D'Amato M; Bergstroem A; Melen E; Scheynius A; Dahlen S-E; Pershagen G; Soderhall C; Kere J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;699(1-3):141-149
Modulation of antigen-induced responses by serotonin and prostaglandin E₂ via EP₁ and EP₄ receptors in the peripheral rat lung
Larsson-Callerfelt A-K; Dahlen S-E; Kuehl A-R; Lex D; Uhlig S; Martin C
Article: CLINICAL AND TRANSLATIONAL ALLERGY. 2013;3:21
Health-related quality of life, assessed with a disease-specific questionnaire, in Swedish adults suffering from well-diagnosed food allergy to staple foods.
Jansson S-A; Heibert-Arnlind M; Middelveld RJ; Bengtsson UJ; Sundqvist A-C; Kallström-Bengtsson I; Marklund B; Rentzos G; Åkerström J; Östblom E; Dahlén S-E; Ahlstedt S
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2013;162(2):135-142
The Influence of Aspirin on Release of Eoxin C4, Leukotriene C4 and 15-HETE, in Eosinophilic Granulocytes Isolated from Patients with Asthma
James A; Daham K; Backman L; Brunnstrom A; Tingvall T; Kumlin M; Edenius C; Dahlen S-E; Dahlen B; Claesson H-E
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2012;303(12):L1027-L1036
Mast cell engraftment of the peripheral lung enhances airway hyperresponsiveness in a mouse asthma model
Fuchs B; Sjoberg L; Westerberg CM; Ekoff M; Swedin L; Dahlen S-E; Adner M; Nilsson GP
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2012;303(11):L956-L966
The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea
Pulkkinen V; Manson ML; Safholm J; Adner M; Dahlen S-E
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2012;68(10):1375-1383
Salbutamol but not ipratropium abolishes leukotriene D₄-induced gas exchange abnormalities in asthma
Dahlen B; Gomez FP; Casas A; Howarth PH; Dahlen S-E; Rodriguez-Roisin R
Article: PLOS ONE. 2012;7(7):e41361
Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility
Reinius LE; Acevedo N; Joerink M; Pershagen G; Dahlen S-E; Greco D; Soderhall C; Scheynius A; Kere J
Article: CLINICAL RESPIRATORY JOURNAL. 2012;6(3):159-168
Update of prevalence of self-reported allergic rhinitis and chronic nasal symptoms among adults in Sweden
Eriksson J; Ekerljung L; Ronmark E; Dahlen B; Ahlstedt S; Dahlen S-E; Lundback B
Article: ALLERGY. 2012;67(7):958-961
Corticosteroid treatment selectively decreases mast cells in the smooth muscle and epithelium of asthmatic bronchi
James A; Gyllfors P; Henriksson E; Dahlen SE; Adner M; Nilsson G; Dahlen B
Article: EUROPEAN RESPIRATORY JOURNAL. 2012;39(6):1458-1467
The European Respiratory Society spirometry tent: a unique form of screening for airway obstruction
Maio S; Sherrill DL; MacNee W; Lange P; Costabel U; Dahlen S-E; Sybrecht GW; Burghuber OC; Stevenson R; Tonnesen P; Haeussinger K; Hedlin G; Bauer TT; Riedler J; Nicod L; Carlsen K-H; Viegi G
Article: LAKARTIDNINGEN. 2012;109(12):622-624
[International guidelines for allergic rhinitis have been updated].
Cardell LO; Wickman M; Hellgren J; Cervin A; Stjärne P; Holmström M; Dahlén B; Bjermer L; Dahlén S-E
Article: PLOS ONE. 2012;7(2):e32110
Intranasal Administration of poly(I:C) and LPS in BALB/c Mice Induces Airway Hyperresponsiveness and Inflammation via Different Pathways
Starkhammar M; Georen SK; Swedin L; Dahlen S-E; Adner M; Cardell LO
Article: ALLERGY. 2012;67(1):91-98
Asthma in adults and its association with chronic rhinosinusitis: The GA2LEN survey in Europe
Jarvis D; Newson R; Lotvall J; Hastan D; Tomassen P; Keil T; Gjomarkaj M; Forsberg B; Gunnbjornsdottir M; Minov J; Brozek G; Dahlen SE; Toskala E; Kowalski ML; Olze H; Howarth P; Kraemer U; Baelum J; Loureiro C; Kasper L; Bousquet PJ; Bousquet J; Bachert C; Fokkens W; Burney P
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2012;158(3):299-306
Challenge of Isolated Sputum Cells Supports in vivo Origin of Intolerance Reaction to Aspirin/Non-Steroidal Anti-Inflammatory Drugs in Asthma
Higashi A; Kumlin M; Higashi N; Daham K; Gaber F; Lindeberg A; James A; Skedinger M; Delin I; Gyllfors P; Dahlen S-E; Dahlen B
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2011;669(1-3):136-142
Prostaglandin D₂ induces contractions through activation of TP receptors in peripheral lung tissue from the guinea pig
Larsson A-K; Hagfjard A; Dahlen S-E; Adner M
Article: ALLERGY. 2011;66(9):1216-1223
Chronic rhinosinusitis in Europe - an underestimated disease. A GA²LEN study
Hastan D; Fokkens WJ; Bachert C; Newson RB; Bislimovska J; Bockelbrink A; Bousquet PJ; Brozek G; Bruno A; Dahlen SE; Forsberg B; Gunnbjornsdottir M; Kasper L; Kraemer U; Kowalski ML; Lange B; Lundback B; Salagean E; Todo-Bom A; Tomassen P; Toskala E; van Drunen CM; Bousquet J; Zuberbier T; Jarvis D; Burney P
Article: ACS NANO. 2011;5(7):5312-5324
Solution-Engineered Palladium Nanoparticles: Model for Health Effect Studies of Automotive Particulate Pollution
Wilkinson KE; Palmberg L; Witasp E; Kupczyk M; Feliu N; Gerde P; Seisenbaeva GA; Fadeel B; Dahlen S-E; Kessler VG
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2011;110(4):1029-1035
The occurrence of refractoriness and mast cell mediator release following mannitol-induced bronchoconstriction
Larsson J; Perry CP; Anderson SD; Brannan JD; Dahlen S-E; Dahlen B
Article: PLOS ONE. 2011;6(2):e16082
Increased Prevalence of Symptoms of Rhinitis but Not of Asthma between 1990 and 2008 in Swedish Adults: Comparisons of the ECRHS and GA²LEN Surveys
Bjerg A; Ekerljung L; Middelveld R; Dahlen S-E; Forsberg B; Franklin K; Larsson K; Lotvall J; Olafsdottir IS; Toren K; Lundback B; Janson C
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2011;41(1):36-45
Effects of celecoxib on major prostaglandins in asthma
Daham K; Song W-L; Lawson JA; Kupczyk M; Gulich A; Dahlen S-E; FitzGerald GA; Dahlen B
Article: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2010;42(10):1853-1860
Effect of Sodium Cromoglycate on Mast Cell Mediators during Hyperpnea in Athletes
Kippelen P; Larsson J; Anderson SD; Brannan JD; Dahlen B; Dahlen SE
Article: LAKARTIDNINGEN. 2010;107(23):1541-1544
[Spirometry screening can identify new cases of asthma and COPD. Public lung function tests at the Stockholm's Central Station].
Renström A; Merritt A-S; Kull I; Hedlin G; Dahlén S-E
Article: PROSTAGLANDINS & OTHER LIPID MEDIATORS. 2010;92(1-4):44-53
Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant
Swedin L; Ellis R; Neimert-Andersson T; Ryrfeldt A; Nilsson G; Inman M; Dahlen S-E; Adner M
Article: INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE. 2010;14(6):764-771
Has the increase in the prevalence of asthma and respiratory symptoms reached a plateau in Stockholm, Sweden?
Ekerljung L; Andersson A; Sundblad B-M; Ronmark E; Larsson K; Ahlstedt S; Dahlen S-E; Lundback B
Article: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2010;42(2):273-280
Acute Effects of Beclomethasone on Hyperpnea-Induced Bronchoconstriction
Kippelen P; Larsson J; Anderson SD; Brannan JD; Delin I; Dahlen B; Dahlen SE
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2010;153(3):249-258
Comparison of Aerosol and Intranasal Challenge in a Mouse Model of Allergic Airway Inflammation and Hyperresponsiveness
Swedin L; Ellis R; Kemi C; Ryrfeldt A; Inman M; Dahlen S-E; Adner M
Article: EUROPEAN RESPIRATORY JOURNAL. 2009;34(1):200-208
Dissociation of airway inflammation and hyperresponsiveness by cyclooxygenase inhibition in allergen challenged mice
Swedin L; Neimert-Andersson T; Hjoberg J; Jonasson S; van Hage M; Adner M; Ryrfeldt A; Dahlen S-E
Article: RESPIRATORY RESEARCH. 2009;10(1):46
Specific mediator inhibition by the NO donors SNP and NCX 2057 in the peripheral lung: implications for allergen-induced bronchoconstriction
Larsson A-K; Baeck M; Lundberg JO; Dahlen S-E
Article: ALLERGY. 2009;64(6):919-926
Prolonged antigen-exposure with carbohydrate particle based vaccination prevents allergic immune responses in sensitized mice
Thunberg S; Neimert-Andersson T; Cheng Q; Wermeling F; Bergstrom U; Swedin L; Dahlen S-E; Arner E; Scheynius A; Karlsson MCI; Gafvelin G; van Hage M; Gronlund H
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Two different mechanisms for modulation of bronchoconstriction in guinea-pigs by cyclooxygenase metabolites
Selg E; Andersson M; Lastbom L; Ryrfeldt A; Dahlen S-E
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2009;179(7):549-558
A Randomized, Double-blind, Placebo-controlled Study of Tumor Necrosis Factor-α Blockade in Severe Persistent Asthma
Wenzel SE; Barnes PJ; Bleecker ER; Bousquet J; Busse W; Dahlen S-E; Holgate ST; Meyers DA; Rabe KF; Antczak A; Baker J; Horvath I; Mark Z; Bernstein D; Kerwin E; Schlenker-Herceg R; Lo KH; Watt R; Barnathan ES; Chanez P
Article: EUROPEAN RESPIRATORY JOURNAL. 2009;33(4):747-753
Effect of formoterol with or without budesonide in repeated low-dose allergen challenge
Dahlen B; Lantz A-S; Ihre E; Skedinger M; Henriksson E; Jorgensen L; Ekstrom T; Dahlen S-E; Larsson K
Article: RESPIRATORY MEDICINE. 2008;102(12):1730-1736
No further increase of incidence of asthma: Incidence, remission and relapse of adult asthma in Sweden
Ekerljung L; Ronmark E; Larsson K; Sundblad B-M; Bjerg A; Ahlstedt S; Dahlen S-E; Lundback B
Article: THORAX. 2008;63(12):1076-1082
Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine and blood from patients with aspirin-intolerant asthma
Gaber F; Daham K; Higashi A; Higashi N; Gulich A; Delin I; James A; Skedinger M; Gyllfors P; Nord M; Dahlen S-E; Kumlin M; Dahlen B
Article: LAKARTIDNINGEN. 2008;105(26-27):1946-1948
[TNF-blockade--new strategy in difficult-to-treat asthma].
Dahlén S-E; Millinger E; Skedinger M; Zetterström O; Dahlén B
Article: ALLERGY. 2008;63(5):518-526
Carbohydrate-based particles reduce allergic inflammation in a mouse model for cat allergy
Neimert-Andersson T; Thunberg S; Swedin L; Wiedermann U; Jacobsson-Ekman G; Dahlen S-E; Scheynius A; Gronlund H; van Hage M; Gafvelin G
Article: RESPIRATORY RESEARCH. 2008;9(1):23
Different effects of deep inspirations on central and peripheral airways in healthy and allergen-challenged mice
Jonasson S; Swedin L; Lundqvist M; Hedenstierna G; Dahlen S-E; Hjoberg J
Article: LAKARTIDNINGEN. 2007;104(51-52):3901
[Wrong to discard antileukotrienes in the treatment of asthma].
Dahlén S-E
Article: ENVIRONMENTAL RESEARCH. 2007;104(2):250-257
Aggregates of ultrafine particles modulate lipid peroxidation and bacterial killing by alveolar macrophages
Lundborg M; Bouhafs R; Gerde P; Ewing P; Camner P; Dahlen S-E; Jarstrand C
Article: PROSTAGLANDINS & OTHER LIPID MEDIATORS. 2007;83(3):209-212
Endothelium-dependent vascular responses induced by leukotriene B₄
Back M; Sakata K; Qiu H; Haeggstrom JZ; Dahlen S-E
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2007;151(1):35-44
A new class of nitric oxide-releasing derivatives of cetirizine;: pharmacological profile in vascular and airway smooth muscle preparations
Larsson A-K; Fumagalli F; DiGennaro A; Andersson M; Lundberg J; Edenius C; Govoni M; Monopoli A; Sala A; Dahlen S-E; Folco GC
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2007;37(4):552-557
Near-fatal asthma phenotype in the ENFUMOSA Cohort.
Romagnoli M; Caramori G; Braccioni F; Ravenna F; Barreiro E; Siafakas NM; Vignola AM; Chanez P; Fabbri LM; Papi A; ENFUMOSA Study Group
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Saliva is one likely source of leukotriene B₄ in exhaled breath condensate
Gaber F; Acevedo F; Delin I; Sundblad B-M; Palmberg L; Larsson K; Kumlin M; Dahlen S-E
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;118(1):78-83
Bronchial responsiveness to leukotriene D₄ is resistant to inhaled fluticasone propionate
Gyllfors P; Dahlen S-E; Kumlin M; Larsson K; Dahlen B
Article: RESPIRATORY MEDICINE. 2006;100(2):226-237
Effects of 5-lipoxygenase inhibitor zileuton on airway responses to inhaled swine house dust in healthy subjects
Larsson BM; Kumlin M; Sundblad BM; Larsson K; Dahlén SE; Palmberg L
Article: ENVIRONMENTAL RESEARCH. 2006;100(2):197-204
Aggregates of ultrafine particles impair phagocytosis of microorganisms by human alveolar macrophages
Lundborg M; Dahlén SE; Johard U; Gerde P; Jarstrand C; Camner P; Låstbom L
Article: THORAX. 2005;60(11):902-908
Relation between bronchial responsiveness to inhaled leukotriene D₄ and markers of leukotriene biosynthesis
Gyllfors P; Kumlin M; Dahlén SE; Gaber F; Ehrs PO; Dahlén B
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2005;315(1):458-465
Inhibition of nitric-oxide synthase enhances antigen-induced contractions and increases release of cysteinyl-leukotrienes in guinea pig lung parenchyma:: Nitric oxide as a protective factor
Larsson AK; Bäck M; Hjoberg J; Dahlén SE
Article: EUROPEAN RESPIRATORY JOURNAL. 2005;26(3):442-448
Leukotriene D₄-induced hypoxaemia in asthma is mediated by the cys-leukotriene₁ receptor
Casas A; Gómez FP; Dahlén B; Roca J; Barberà JA; Dahlén SE; Rodríguez-Roisin R
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2005;35(7):954-959
Risk factors and characteristics associated with severe and difficult to treat asthma phenotype: an analysis of the ENFUMOSA group of patients based on the ECRHS questionnaire.
Gaga M; Papageorgiou N; Yiourgioti G; Karydi P; Liapikou A; Bitsakou H; Zervas E; Koulouris NG; Holgate ST; ENFUMOSA Study Group
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2004;141(3):449-456
The contractile action of leukotriene B₄ in the guinea-pig lung involves a vascular component
Sakata K; Dahlén SE; Bäck M
Article: RESPIRATORY MEDICINE. 2003;97(11):1225-1229
High levels of urinary leukotriene E₄ excretion in steroid treated patients with severe asthma
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Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung
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Improvement of asprinin-intolerant asthma by montelukast, a leukotriene antagonist -: A randomized, double-blink, placebo-controlled trial
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An alternative pathway for metabolism of leukotriene D₄:: effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea
Bäck M; Kumlin M; Cotgreave IA; Dahlén SE
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2001;164(2):202-206
Pulmonary gas exchange and sputum cellular responses to inhaled leukotriene D₄ in asthma
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Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2001;31(3):400-408
Benefits of high altitude allergen avoidance in atopic adolescents with moderate to severe asthma, over and above treatment with high dose inhaled steroids
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Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2000;401(3):389-395
Prostacyclin modulation of contractions of the human pulmonary artery by cysteinyl-leukotrienes
Bäck M; Norel X; Walch L; Gascard JP; de Montpreville V; Dahlén SE; Brink C
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2000;401(3):381-388
Antagonist resistant contractions of the porcine pulmonary artery by cysteinyl-leukotrienes
Bäck M; Norel X; Walch L; Gascard JP; Mazmanian G; Dahlén SE; Brink C
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Markers of inflammation and bronchial reactivity in children with asthma, exposed to animal dander in school dust
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Leukotriene C₄ is a tight-binding inhibitor of microsomal glutathione transferase-1 -: Effects of leukotriene pathway modifiers
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Exposure of healthy volunteers to swine house dust increases formation of leukotrienes, prostaglandin D₂, and bronchial responsiveness to methacholine
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Urinary excretion of inflammatory mediators during allergen-induced early and late phase asthmatic reactions
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Agonist and antagonist activities of the leukotriene analogue BAY u9773 in guinea pig lung parenchyma
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Article: EUROPEAN RESPIRATORY JOURNAL. 1998;12(2):345-350
Evidence for mast cell activation during exercise-induced bronchoconstriction
O'Sullivan S; Roquet A; Dahlen B; Larsen F; Eklund A; Kumlin M; O'Byrne PM; Dahlen SE
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Inhibition of allergen-induced airway obstruction and leukotriene generation in atopic asthmatic subjects by the leukotriene biosynthesis inhibitor BAYx 1005
Dahlen B; Kumlin M; Ihre E; Zetterstrom O; Dahlen SE
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The cysteinyl-leukotriene receptor antagonist BAY u9773 is a competitive antagonist of leukotriene C-4 in the guinea-pig ileum
Back M; Jonsson EW; Dahlen SE
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Increased urinary excretion of the prostaglandin D-2 metabolite 9 alpha,11 beta-prostaglandin F-2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction
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Formation of a novel enzymatic metabolite of leukotriene A(4) in tissues of Xenopus laevis
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Raud J; Hallden G; Roquet A; vanHageHamsten M; Alkner U; Hed J; Zetterstrom O; Dahlen SE; Hedqvist P; Gronneberg R
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Ivancevich JC; Neffen H; Zernotti ME; Kull I; Melen E; Wickman M; Bachert C; Hellings PW; Brusselle G; Palkonen S; Bindslev-Jensen C; Eller E; Waserman S; Boulet LP; Bouchard J; Chu DK; Schunemann HJ; Sova M; De Vries G; van Eerd M; Agache I; Ansotegui IJ; Bewick M; Casale T; Dykewick M; Ebisawa M; Murray R; Naclerio R; Okamoto Y; Wallace DV; Hellings PW; Aberer W; Agache I; Akdis CA; Akdis M; Aliberti MR; Almeida R; Amat F; Angles R; Annesi-Maesano I; Ansotegui IJ; Anto JM; Arnavielle S; Asayag E; Asarnoj A; Arshad H; Avolio F; Bacci E; Bachert C; Baiardini I; Barbara C; Barbagallo M; Baroni I; Barreto BA; Basagana X; Bateman ED; Bedolla-Barajas M; Bedbrook A; Bewick M; Beghe B; Bel EH; Bergmann KC; Bennoor KS; Benson M; Bertorello L; Bialoszewski AZ; Bieber T; Bialek S; Bindslev-Jensen C; Bjermer L; Blain H; Blasi F; Blua A; Marciniak MB; Bogus-Buczynska I; Boner AL; Bonini M; Bonini S; Bosnic-Anticevich CS; Bosse I; Bouchard J; Boulet LP; Bourret R; Bousquet PJ; Braido F; Briedis V; Brightling CE; Brozek J; Bucca C; Buhl R; Buonaiuto R; Panaitescu C; Cabanas MTB; Burte E; Bush A; Caballero-Fonseca F; Caillaud D; Caimmi D; Calderon MA; Camargos PAM; Camuzat T; Canfora G; Canonica GW; Cardona V; Carlsen KH; Carreiro-Martins P; Carriazo AM; Carr W; Cartier C; Casale T; Castellano G; Cecchi L; Cepeda AM; Chavannes NH; Chen Y; Chiron R; Chivato T; Chkhartishvili E; Chuchalin AG; Chung KF; Ciaravolo MM; Ciceran A; Cingi C; Ciprandi G; Coehlo ACC; Colas L; Colgan E; Coll J; Conforti D; De Sousa JC; Cortes-Grimaldo RM; Corti F; Costa E; Costa-Dominguez MC; Courbis AL; Cox L; Crescenzo M; Cruz AA; Custovic A; Czarlewski W; Dahlen SE; D'Amato G; Dario C; da Silva J; Dauvilliers Y; Darsow U; De Blay F; De Carlo G; Dedeu T; Emerson MDF; De Feo G; De Vries G; De Martino B; Rubina NPM; Deleanu D; Demoly P; Denburg JA; Devillier P; Ercolano SDC; Di Carluccio N; Didier A; Dokic D; Dominguez-Silva MG; Douagui H; Dray G; Dubakiene R; Durham SR; Du Toit G; Dykewicz MS; El-Gamal Y; Eklund P; Eller E; Emuzyte R; Farrell J; Farsi A; Ferreira DMJJ; Ferrero J; Fink-Wagner A; Fiocchi A; Fokkens WJ; Fonseca JA; Fontaine JF; Forti S; Fuentes-Perez JM; Galvez-Romero JL; Gamkrelidze A; Garcia-Aymerich J; Garcia-Cobas CY; Garcia-Cruz MH; Gemicioglu B; Genova S; Christoff G; Gereda JE; van Wijk RG; Gomez RM; Gomez-Vera J; Diaz SG; Gotua M; Grisle I; Guidacci M; Guldemond NA; Gutter Z; Guzman MA; Haahtela T; Hajjam J; Hernandez L; Hourihane JOB; Huerta-Villalobos YR; Humbert M; Iaccarino G; Illario M; Ispayeva Z; Ivancevich JC; Jares EJ; Jassem E; Johnston SL; Joos G; Jung KS; Just J; Jutel M; Kaidashev I; Kalayci O; Kalyoncu AF; Karjalainen J; Kardas P; Keil T; Keith PK; Khaitov M; Khaltaev N; Kleine-Tebbe J; Klimek L; Kowalski ML; Kuitunen M; Kull I; Kuna P; Kupczyk M; Kvedariene V; Krzych-Falta E; Lacwik P; Larenas-Linnemann D; Laune D; Lauri D; Lavrut J; Le LTT; Lessa M; Levato G; Li J; Lieberman P; Lipiec A; Lipworth B; Carlsen KCL; Louis R; Lourenco O; Luna-Pech JA; Magnan A; Mahboub B; Maier D; Mair A; Majer I; Malva J; Mandajieva E; Manning P; Keenoy EDM; Marshall GD; Masjedi MR; Maspero JF; Mathieu-Dupas E; Campos JJM; Matos AL; Maurer M; Mavale-Manuel S; Mayora O; Medina-Avalos MA; Melen E; Melo-Gomes E; Meltzer EO; Menditto E; Mercier J; Miculinic N; Mihaltan F; Milenkovic B; Moda G; Mogica-Martinez MD; Mohammad Y; Momas I; Montefort S; Monti R; Bogado DM; Morais-Almeida M; Morato-Castro FF; Mosges R; Mota-Pinto A; Santo PM; Mullol J; Munter L; Muraro A; Murray R; Naclerio R; Nadif R; Nalin M; Napoli L; Namazova-Baranova L; Neffen H; Niedeberger V; Nekam K; Neou A; Nieto A; Nogueira-Silva L; Nogues M; Novellino E; Nyembue TD; O'Hehir RE; Odzhakova C; Ohta K; Okamoto Y; Okubo K; Onorato GL; Cisneros MO; Ouedraogo S; Pali-Scholl I; Palkonen S; Panzner P; Papadopoulos NG; Park HS; Papi A; Passalacqua G; Paulino E; Pawankar R; Pedersen S; Pepin JL; Pereira AM; Persico M; Pfaar O; Phillips J; Picard R; Pigearias B; Pin I; Pitsios C; Plavec D; Pohl W; Popov TA; Portejoie F; Potter P; Pozzi AC; Price D; Prokopakis EP; Puy R; Pugin B; Ross REP; Przemecka M; Rabe KF; Raciborski F; Rajabian-Soderlund R; Reitsma S; Ribeirinho I; Rimmer J; Rivero-Yeverino D; Rizzo JA; Rizzo MC; Robalo-Cordeiro C; Rodenas F; Rodo X; Gonzalez MR; Rodriguez-Manas L; Rolland C; Valle SR; Rodriguez MR; Romano A; Rodriguez-Zagal E; Rolla G; Roller-Wirnsberger RE; Romano M; Rosado-Pinto J; Rosario N; Rottem M; Ryan D; Sagara H; Salimaki J; Samolinski B; Sanchez-Borges M; Sastre-Dominguez J; Scadding GK; Schunemann HJ; Scichilone N; Schmid-Grendelmeier P; Serpa FS; Shamai S; Sheikh A; Sierra M; Simons FER; Siroux V; Sisul JC; Skrindo I; Sole D; Somekh D; Sondermann M; Sooronbaev T; Sova M; Sorensen M; Sorlini M; Spranger O; Stellato C; Stelmach R; Stukas R; Sunyer J; Strozek J; Szylling A; Tebyrica JN; Thibaudon M; To T; Todo-Bom A; Tomazic PV; Toppila-Salmi S; Trama U; Triggiani M; Ulrik CS; Urrutia-Pereira M; Valenta R; Valero A; Valiulis A; Valovirta E; van Eerd M; van Ganse E; van Hague M; Vandenplas O; Ventura MT; Vezzani G; Vasankari T; Vatrella A; Verissimo MT; Viart F; Viegi G; Vicheva D; Vontetsianos T; Wagenmann M; Walker S; Wallace D; Wang DY; Waserman S; Werfel T; Westman M; Wickman M; Williams DM; Williams S; Wilson N; Wright J; Wroczynski P; Yakovliev P; Yawn BP; Yiallouros PK; Yorgancioglu A; Yusuf OM; Zar HJ; Zhang L; Zhong N; Zernotti ME; Zhanat I; Zidarn M; Zuberbier T; Zubrinich C; Zurkuhlen A
Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(3):864-879
Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology
Bousquet J; Hellings PW; Agache I; Amat F; Annesi-Maesano I; Ansotegui IJ; Anto JM; Bachert C; Bateman ED; Bedbrook A; Bennoor K; Bewick M; Bindslev-Jensen C; Bosnic-Anticevich S; Bosse I; Brozek J; Brussino L; Canonica GW; Cardona V; Casale T; Sarabia AMC; Chavannes NH; Cecchi L; de Sousa JC; Costa E; Cruz AA; Czarlewski W; De Carlo G; De Feo G; Demoly P; Devillier P; Dykewicz MS; El-Gamal Y; Eller EE; Fonseca JA; Fontaine J-F; Fokkens WJ; Guzman M-A; Haahtela T; Illario M; Ivancevich J-C; Just J; Kaidashev I; Khaitov M; Kalayci O; Keil T; Klimek L; Kowalski ML; Kuna P; Kvedariene V; Larenas-Linnemann D; Laune D; Le LTT; Carlsen KL; Lourenco O; Mahboub B; Mair A; Menditto E; Milenkovic B; Morais-Almeida M; Mosges R; Mullol J; Murray R; Naclerio R; Namazova-Baranova L; Novellino E; O'Hehir RE; Ohta K; Okamoto Y; Okubo K; Onorato GL; Palkonen S; Panzner P; Papadopoulos NG; Park H-S; Paulino E; Pawankar R; Pfaar O; Plavec D; Popov TA; Potter P; Prokopakis EP; Rottem M; Ryan D; Salimaki J; Samolinski B; Sanchez-Borges M; Schunemann HJ; Sheikh A; Sisul J-C; Rajabian-Soderlund R; Sooronbaev T; Stellato C; To T; Todo-Bom A-M; Tomazic P-V; Toppila-Salmi S; Valero A; Valiulis A; Valovirta E; Ventura M-T; Wagenmann M; Wang DY; Wallace D; Waserman S; Wickman M; Yorgancioglu A; Zhang L; Zhong N; Zidarn M; Zuberbier T; Bousquet J; Hellings PW; Aberer W; Agache I; Akdis CA; Akdis M; Alberti MR; Almeida R; Amat F; Angles R; Annesi-Maesano I; Ansotegui IJ; Anto JM; Arnavielle S; Asayag E; Asarnoj A; Arshad H; Avolio F; Bacci E; Bachert C; Baiardini I; Barbara C; Barbagallo M; Baroni I; Barreto BA; Basagana X; Bateman ED; Bedolla-Barajas M; Bedbrook A; Bewick M; Beghe B; Bel EH; Bergmann KC; Bennoor KS; Benson M; Bertorello L; Biaoszewski AZ; Bieber T; Bialek S; Bindslev-Jensen C; Bjermer L; Blain H; Blasi F; Blua A; Marciniak MB; Bogus-Buczynska I; Boner AL; Bonini M; Bonini S; Bosnic-Anticevich CS; Bosse I; Bouchard J; Boulet LP; Bourret R; Bousquet PJ; Braido F; Briedis V; Brightling CE; Brozek J; Bucca C; Buhl R; Buonaiuto R; Panaitescu C; Cabanas MTB; Burte E; Bush A; Caballero-Fonseca F; Caillot D; Caimmi D; Calderon MA; Camargos PAM; Camuzat T; Canfora G; Canonica GW; Cardona V; Carlsen KH; Carreiro-Martins P; Carriazo AM; Carr W; Cartier C; Casale T; Castellano G; Cecchi L; Sarabia AMC; Chavannes NH; Chen Y; Chiron R; Chivato T; Chkhartishvili E; Chuchalin AG; Chung KF; Ciaravolo MM; Ciceran A; Cingi C; Ciprandi G; Coehlo ACC; Colas L; Colgan E; Coll J; Conforti D; de Sousa JC; Cortes-Grimaldo RM; Corti F; Costa E; Costa-Dominguez C; Courbis AL; Cox L; Crescenzo M; Cruz AA; Custovic A; Czarlewski W; Dahlen SE; Dario C; da Silva J; Dauvilliers Y; Darsow U; De Blay F; De Carlo G; Dedeu T; Emerson MDF; De Feo G; De Vries G; De Martino B; Rubini NDPM; Deleanu D; Demoly P; Denburg JA; Devillier P; Ercolano SDC; Di Carluccio N; Didier A; Dokic D; Dominguez-Silva MG; Douagui H; Dray G; Dubakiene R; Durham SR; Du Toit G; Dykewicz MS; El-Gamal Y; Eklund P; Eller E; Emuzyte R; Farrell J; Farsi A; de MJFJ; Ferrero J; Fink-Wagner A; Fiocchi A; Fokkens WJ; Fonseca JA; Fontaine JF; Forti S; Fuentes-Perez JM; Galvez-Romero JL; Gamkrelidze A; Garcia-Aymerich J; Garcia-Cobas CY; Garcia-Cruz MH; Gemicioglu B; Genova S; Christoff G; Gereda JE; van Wijk RG; Gomez RM; Gomez-Vera J; Diaz SG; Gotua M; Grisle I; Guidacci M; Guldemond NA; Gutter Z; Guzman MA; Haahtela T; Hajjam J; Hernandez L; Hourihane JO; Huerta-Villalobos YR; Humbert M; Iaccarino G; Illario M; Ivancevich JC; Jares EJ; Jassem E; Johnston SL; Joos G; Jung KS; Jutel M; Kaidashev I; Kalayci O; Kalyoncu AF; Karjalainen J; Kardas P; Keil T; Keith PK; Khaitov M; Khaltaev N; Kleine-Tebbe J; Klimek L; Kowalski ML; Kuitunen M; Kull I; Kuna P; Kupczyk M; Kvedariene V; Krzych-Fata E; Lacwik P; Larenas-Linnemann D; Laune D; Lauri D; Lavrut J; Le LTT; Lessa M; Levato G; Li J; Lieberman P; Lipiec A; Lipworth B; Carlsen KCL; Louis R; Lourenco O; Luna-Pech JA; Maciej K; Magnan A; Mahboub B; Maier D; Mair A; Majer I; Malva J; Mandajieva E; Manning P; Keenoy EDM; Marshall GD; Masjedi MR; Maspero JF; Mathieu-Dupas E; Campos JJM; Matos AL; Maurer M; Mavale-Manuel S; Mayora O; Medina-Avalos MA; Melen E; Melo-Gomes E; Meltzer EO; Menditto E; Mercier J; Miculinic N; Mihaltan F; Milenkovic B; Moda G; Mogica-Martinez MD; Mohammad Y; Momas I; Montefort S; Monti R; Bogado DM; Morais-Almeida M; Morato-Castro FF; Mosges R; Mota-Pinto A; Santo PM; Mullol J; Munter L; Muraro A; Murray R; Naclerio R; Nadif R; Nalin M; Napoli L; Namazova-Baranova L; Neffen H; Niedeberger V; Nekam K; Neou A; Nieto A; Nogueira-Silva L; Nogues M; Novellino E; Nyembue TD; O'Hehir RE; Odzhakova C; Ohta K; Okamoto Y; Okubo K; Onorato GL; Cisneros MO; Ouedraogo S; Pali-Scholl I; Palkonen S; Panzner P; Papadopoulos NG; Park HS; Papi A; Passalacqua G; Paulino E; Pawankar R; Pedersen S; Pepin JL; Pereira AM; Persico M; Pfaar O; Phillips J; Picard R; Pigearias B; Pin I; Pitsios C; Plavec D; Pohl W; Popov TA; Portejoie F; Potter P; Pozzi AC; Price D; Prokopakis EP; Puy R; Pugin B; Ross REP; Przemecka M; Rabe KF; Raciborski F; Rajabian-Soderlund R; Reitsma S; Ribeirinho I; Rimmer J; Rivero-Yeverino D; Rizzo JA; Rizzo MC; Robalo-Cordeiro C; Rodenas F; Rodo X; Gonzalez MR; Rodriguez-Manas L; Rolland C; Valle SR; Rodriguez MR; Romano A; Rodriguez-Zagal E; Rolla G; Roller-Wirnsberger RE; Romano M; Rosado-Pinto J; Rosario N; Rottem M; Ryan D; Sagara H; Salimaki J; Samolinski B; Sanchez-Borges M; Sastre-Dominguez J; Scadding GK; Schunemann HJ; Scichilone N; Schmid-Grendelmeier P; Serpa FS; Shamai S; Sheikh A; Sierra M; Simons FER; Siroux V; Sisul JC; Skrindo I; Sole D; Somekh D; Sondermann M; Sooronbaev T; Sova M; Sorensen M; Sorlini M; Spranger O; Stellato C; Stelmach R; Stukas R; Sunyer J; Strozek J; Szylling A; Tebyrica JN; Thibaudon M; To T; Todo-Bom A; Tomazic PV; Toppila-Salmi S; Trama U; Triggiani M; Ulrik CS; Urrutia-Pereira M; Valenta R; Valero A; Valiulis A; Valovirta E; van Eerd M; van Ganse E; van Hague M; Vandenplas O; Ventura MT; Vezzani G; Vasankari T; Vatrella A; Verissimo MT; Viart F; Viegi M; Vicheva D; Vontetsianos T; Wagenmann M; Walker S; Wallace D; Wang DY; Waserman S; Werfel T; Westman M; Wickman M; Williams DM; Williams S; Wilson N; Wright J; Wroczynski P; Yakovliev P; Yawn BP; Yiallouros PK; Yorgancioglu A; Yusuf OM; Zar HJ; Zhang L; Zhong N; Zernotti ME; Zidarn M; Zuberbier T; Zubrinich C; Zurkuhlen A
Letter: ALLERGY. 2019;74(2):406-411
Treatable traits in the European U-BIOPRED adult asthma cohorts
Simpson AJ; Hekking P-P; Shaw DE; Fleming LJ; Roberts G; Riley JH; Bates S; Sousa AR; Bansal AT; Pandis I; Sun K; Bakke PS; Caruso M; Dahlen B; Dahlen S-E; Horvath I; Krug N; Montuschi P; Sandstrom T; Singer F; Adcock IM; Wagers SS; Djukanovic R; Chung KF; Sterk PJ; Fowler SJ; Adcock IM; Ahmed H; Auffray C; Bakke P; Bansal AT; Baribaud F; Bates S; Bel EH; Bigler J; Bisgaard H; Boedigheimer MJ; Bonnelykke K; Brandsma J; Brinkman P; Bucchioni E; Burg D; Bush A; Caruso M; Chaiboonchoe A; Chanez P; Chung FK; Compton CH; Corfield J; D'Amico A; Dahlen B; Dahlen SE; De Meulder B; Djukanovic R; Erpenbeck VJ; Erzen D; Fichtner K; Fitch N; Fleming LJ; Formaggio E; Fowler SJ; Frey U; Gahlemann M; Geiser T; Goss V; Guo Y; Hashimoto S; Haughney J; Hedlin G; Hekking PW; Higenbottam T; Hohlfeld JM; Holweg C; Horvath I; Howarth P; James AJ; Knowles R; Knox AJ; Krug N; Lefaudeux D; Loza MJ; Lutter R; Manta A; Masefield S; Matthews JG; Mazein A; Meiser A; Middelveld RJM; Miralpeix M; Montuschi P; Mores N; Murray CS; Musial J; Myles D; Pahus L; Pandis I; Pavlidis S; Postle A; Powel P; Pratico G; Puig Valls M; Rao N; Riley J; Roberts A; Roberts G; Rowe A; Sandstrom T; Schofield JPR; Seibold W; Selby A; Shaw DE; Sigmund R; Singer F; Skipp PJ; Sousa AR; Sterk PJ; Sun K; van Aalderen WM; van Geest M; Vestbo J; Vissing NH; Wagener AH; Wagers SS; Weiszhart Z; Wheelock CE; Wilson SJ
Editorial comment: RESPIROLOGY. 2018;23(7):654-655
International research collaboration: The way forward
Chotirmall SH; Dahlen S-E; Carlsten C; Wong WSF; Chung KF; Gosens R; Knight DA
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;140(5):1459-1461.e2
RNA-containing exosomes in induced sputum of asthmatic patients
Sanchez-Vidaurre S; Eldh M; Larssen P; Daham K; Martinez-Bravo M-J; Dahlen S-E; Dahlen B; van Hage M; Gabrielsson S
Corrigendum: CLINICAL AND TRANSLATIONAL ALLERGY. 2017;7:5
Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5) (vol 6, 29, 2016)
Bousquet J; Farrell J; Crooks G; Hellings P; Bel EH; Bewick M; Chavannes NH; de Sousa JC; Cruz AA; Haahtela T; Joos G; Khaltaev N; Malva J; Muraro A; Nogues M; Palkonen S; Pedersen S; Robalo-Cordeiro C; Samolinski B; Strandberg T; Valiulis A; Yorgancioglu A; Zuberbier T; Bedbrook A; Aberer W; Adachi M; Agusti A; Akdis CA; Akdis M; Ankri J; Alonso A; Annesi-Maesano I; Ansotegui IJ; Anto JM; Arnavielhe S; Arshad H; Bai C; Baiardini I; Bachert C; Baigenzhin AK; Barbara C; Bateman ED; Beghe B; Ben Kheder A; Bennoor KS; Benson M; Bergmann KC; Bieber T; Bindslev-Jensen C; Bjermer L; Blain H; Blasi F; Boner AL; Bonini M; Bonini S; Bosnic-Anticevitch S; Boulet LP; Bourret R; Bousquet PJ; Braido F; Briggs AH; Brightling CE; Brozek J; Buhl R; Burney PG; Bush A; Caballero-Fonseca F; Caimmi D; Calderon MA; Calverley PM; Camargos PAM; Canonica GW; Camuzat T; Carlsen KH; Carr W; Carriazo A; Casale T; Sarabia AMC; Chatzi L; Chen YZ; Chiron R; Chkhartishvili E; Chuchalin AG; Chung KF; Ciprandi G; Cirule I; Cox L; Costa DJ; Custovic A; Dahl R; Dahlen SE; Darsow U; De Carlo G; De Blay F; Dedeu T; Deleanu D; Keenoy EDM; Demoly P; Denburg JA; Devillier P; Didier A; Dinh-Xuan AT; Djukanovic R; Dokic D; Douagui H; Dray G; Dubakiene R; Durham SR; Dykewicz MS; El-Gamal Y; Emuzyte R; Fabbri LM; Fletcher M; Fiocchi A; Wagner AF; Fonseca J; Fokkens WJ; Forastiere F; Frith P; Gaga M; Gamkrelidze A; Garces J; Garcia-Aymerich J; Gemicioglu B; Gereda JE; Diaz SG; Gotua M; Grisle I; Grouse L; Gutter Z; Guzman MA; Heaney LG; Hellquist-Dahl B; Henderson D; Hendry A; Heinrich J; Heve D; Horak F; Hourihane JOB; Howarth P; Humbert M; Hyland ME; Illario M; Ivancevich JC; Jardim JR; Jares EJ; Jeandel C; Jenkins C; Johnston SL; Jonquet O; Julge K; Jung KS; Just J; Kaidashev I; Khaitov MR; Kalayci O; Kalyoncu AF; Keil T; Keith PK; Klimek L; N'Goran BK; Kolek V; Koppelman GH; Kowalski ML; Kull I; Kuna P; Kvedariene V; Lambrecht B; Lau S; Larenas-Linnemann D; Laune D; Le LTT; Lieberman P; Lipworth B; Li J; Carlsen KL; Louis R; MacNee W; Magard Y; Magnan A; Mahboub B; Mair A; Majer I; Makela MJ; Manning P; Mara S; Marshall GD; Masjedi MR; Matignon P; Maurer M; Mavale-Manuel S; Melen E; Melo-Gomes E; Meltzer EO; Menzies-Gow A; Merk H; Michel JP; Miculinic N; Mihaltan F; Milenkovic B; Mohammad GMY; Molimard M; Momas I; Montilla-Santana A; Morais-Almeida M; Morgan M; Mosges R; Mullol J; Nafti S; Namazova-Baranova L; Naclerio R; Neou A; Neffen H; Nekam K; Niggemann B; Ninot G; Nyembue TD; O'Hehir RE; Ohta K; Okamoto Y; Okubo K; Ouedraogo S; Paggiaro P; Pali-Scholl I; Panzner P; Papadopoulos N; Papi A; Park HS; Passalacqua G; Pavord I; Pawankar R; Pengelly R; Pfaar O; Picard R; Pigearias B; Pin I; Plavec D; Poethig D; Pohl W; Popov TA; Portejoie F; Potter P; Postma D; Price D; Rabe KF; Raciborski F; Pontal FR; Repka-Ramirez S; Reitamo S; Rennard S; Rodenas F; Roberts J; Roca J; Manas LR; Rolland C; Rodriguez MR; Romano A; Rosado-Pinto J; Rosario N; Rosenwasser L; Rottem M; Ryan D; Sanchez-Borges M; Scadding GK; Schunemann HJ; Serrano E; Schmid-Grendelmeier P; Schulz H; Sheikh A; Shields M; Siafakas N; Sibille Y; Similowski T; Simons FER; Sisul JC; Skrindo I; Smit HA; Sole D; Sooronbaev T; Spranger O; Stelmach R; Sterk PJ; Sunyer J; Thijs C; To T; Todo-Bom A; Triggiani M; Valenta R; Valero AL; Valia E; Valovirta E; Van Ganse E; van Hage M; Vandenplas O; Vasankari T; Vellas B; Vestbo J; Vezzani G; Vichyanond P; Viegi G; Vogelmeier C; Vontetsianos T; Wagenmann M; Wallaert B; Walker S; Wang DY; Wahn U; Wickman M; Williams DM; Williams S; Wright J; Yawn BP; Yiallouros PK; Yusuf OM; Zaidi A; Zar HJ; Zernotti ME; Zhang L; Zhong N; Zidarn M; Mercier J
Review: CLINICAL AND TRANSLATIONAL ALLERGY. 2016;6:47
ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle
Bousquet J; Hellings PW; Agache I; Bedbrook A; Bachert C; Bergmann KC; Bewick M; Bindslev-Jensen C; Bosnic-Anticevitch S; Bucca C; Caimmi DP; Camargos PAM; Canonica GW; Casale T; Chavannes NH; Cruz AA; De Carlo G; Dahl R; Demoly P; Devillier P; Fonseca J; Fokkens WJ; Guldemond NA; Haahtela T; Illario M; Just J; Keil T; Klimek L; Kuna P; Larenas-Linnemann D; Morais-Almeida M; Mullol J; Murray R; Naclerio R; O'Hehir RE; Papadopoulos NG; Pawankar R; Potter P; Ryan D; Samolinski B; Schunemann HJ; Sheikh A; Simons FER; Stellato C; Todo-Bom A; Tomazic PV; Valiulis A; Valovirta E; Ventura MT; Wickman M; Young I; Yorgancioglu A; Zuberbier T; Aberer W; Akdis CA; Akdis M; Annesi-Maesano I; Ankri J; Ansotegui IJ; Anto JM; Arnavielhe S; Asarnoj A; Arshad H; Avolio F; Baiardini I; Barbara C; Barbagallo M; Bateman ED; Beghe B; Bel EH; Bennoor KS; Benson M; Bialoszewski AZ; Bieber T; Bjermer L; Blain H; Blasi F; Boner AL; Bonini M; Bonini S; Bosse I; Bouchard J; Boulet LP; Bourret R; Bousquet PJ; Braido F; Briggs AH; Brightling CE; Brozek J; Buhl R; Bunu C; Burte E; Bush A; Caballero-Fonseca F; Calderon MA; Camuzat T; Cardona V; Carreiro-Martins P; Carriazo AM; Carlsen KH; Carr W; Cepeda Sarabia AM; Cesari M; Chatzi L; Chiron R; Chivato T; Chkhartishvili E; Chuchalin AG; Chung KF; Ciprandi G; Correia de Sousa J; Cox L; Crooks G; Custovic A; Dahlen SE; Darsow U; Dedeu T; Deleanu D; Denburg JA; De Vries G; Didier A; Dinh-Xuan AT; Dokic D; Douagui H; Dray G; Dubakiene R; Durham SR; Du Toit G; Dykewicz MS; Eklund P; El-Gamal Y; Ellers E; Emuzyte R; Farrell J; Wagner AF; Fiocchi A; Fletcher M; Forastiere F; Gaga M; Gamkrelidze A; Gemicioglu B; Gereda JE; van Wick RG; Gonzalez Diaz S; Grisle I; Grouse L; Gutter Z; Guzman MA; Hellquist-Dahl B; Heinrich J; Horak F; Hourihane JOB; Humbert M; Hyland M; Iaccarino G; Jares EJ; Jeandel C; Johnston SL; Joos G; Jonquet O; Jung KS; Jutel M; Kaidashev I; Khaitov M; Kalayci O; Kalyoncu AF; Kardas P; Keith PK; Kerkhof M; Kerstjens HAM; Khaltaev N; Kogevinas M; Kolek V; Koppelman GH; Kowalski ML; Kuitunen M; Kull I; Kvedariene V; Lambrecht B; Lau S; Laune D; Le LTT; Lieberman P; Lipworth B; Li J; Carlsen KCL; Louis R; Lupinek C; MacNee W; Magar Y; Magnan A; Mahboub B; Maier D; Majer I; Malva J; Manning P; De Manuel Keenoy E; Marshall GD; Masjedi MR; Mathieu-Dupas E; Maurer M; Mavale-Manuel S; Melen E; Melo-Gomes E; Meltzer EO; Mercier J; Merk H; Miculinic N; Mihaltan F; Milenkovic B; Millot-Keurinck J; Mohammad Y; Momas I; Mosges R; Muraro A; Namazova-Baranova L; Nadif R; Neffen H; Nekam K; Nieto A; Niggemann B; Nogueira-Silva L; Nogues M; Nyembue TD; Ohta K; Okamoto Y; Okubo K; Olive-Elias M; Ouedraogo S; Paggiaro P; Pali-Schoell I; Palkonen S; Panzner P; Papi A; Park HS; Passalacqua G; Pedersen S; Pereira AM; Pfaar O; Picard R; Pigearias B; Pin I; Plavec D; Pohl W; Popov TA; Portejoie F; Postma D; Poulsen LK; Price D; Rabe KF; Raciborski F; Roberts G; Robalo-Cordeiro C; Rodenas F; Rodriguez-Manas L; Rolland C; Roman Rodriguez M; Romano A; Rosado-Pinto J; Rosario N; Rottem M; Sanchez-Borges M; Sastre-Dominguez J; Scadding GK; Scichilone N; Schmid-Grendelmeier P; Serrano E; Shields M; Siroux V; Sisul JC; Skrindo I; Smit HA; Sole D; Sooronbaev T; Spranger O; Stelmach R; Sterk PJ; Strandberg T; Sunyer J; Thijs C; Triggiani M; Valenta R; Valero A; van Eerd M; van Ganse E; van Hague M; Vandenplas O; Varona LL; Vellas B; Vezzani G; Vazankari T; Viegi G; Vontetsianos T; Wagenmann M; Walker S; Wang DY; Wahn U; Werfel T; Whalley B; Williams DM; Williams S; Wilson N; Wright J; Yawn BP; Yiallouros PK; Yusuf OM; Zaidi A; Zar HJ; Zernotti ME; Zhang L; Zhong N; Zidarn M
Editorial comment: CLINICAL AND EXPERIMENTAL ALLERGY. 2016;46(9):1136-1138
Building the investment case for asthma R&D: the European Asthma Research and Innovation Partnership argument
Walker SM; Akdis C; Dahlen SE; Djukanovic R; Edwards J; Garcia-Marcos L; Johnston S; Kupczyk M; Martin T; Myles D; Palkonen S; Papadopoulos N; Powell P; Riley J
Review: CLINICAL AND TRANSLATIONAL ALLERGY. 2016;6:29
Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)
Bousquet J; Farrell J; Crooks G; Hellings P; Bel EH; Bewick M; Chavannes NH; de Sousa JC; Cruz AA; Haahtela T; Joos G; Khaltaev N; Malva J; Muraro A; Nogues M; Palkonen S; Pedersen S; Robalo-Cordeiro C; Samolinski B; Strandberg T; Valiulis A; Yorgancioglu A; Zuberbier T; Bedbrook A; Aberer W; Adachi M; Agusti A; Akdis CA; Akdis M; Ankri J; Alonso A; Annesi-Maesano I; Ansotegui IJ; Anto JM; Arnavielhe S; Arshad H; Bai C; Baiardini I; Bachert C; Baigenzhin AK; Barbara C; Bateman ED; Beghe B; Ben Kheder A; Bennoor KS; Benson M; Bergmann KC; Bieber T; Bindslev-Jensen C; Bjermer L; Blain H; Blasi F; Boner AL; Bonini M; Bonini S; Bosnic-Anticevitch S; Boulet LP; Bourret R; Bousquet PJ; Braido F; Briggs AH; Brightling CE; Brozek J; Buhl R; Burney PG; Bush A; Caballero-Fonseca F; Caimmi D; Calderon MA; Calverley PM; Camargos PAM; Canonica GW; Camuzat T; Carlsen KH; Carr W; Carriazo A; Casale T; Sarabia AMC; Chatzi L; Chen YZ; Chiron R; Chkhartishvili E; Chuchalin AG; Chung KF; Ciprandi G; Cirule I; Cox L; Costa DJ; Custovic A; Dahl R; Dahlen SE; Darsow U; De Carlo G; De Blay F; Dedeu T; Deleanu D; Keenoy EDM; Demoly P; Denburg JA; Devillier P; Didier A; Dinh-Xuan AT; Djukanovic R; Dokic D; Douagui H; Dray G; Dubakiene R; Durham SR; Dykewicz MS; El-Gamal Y; Emuzyte R; Fabbri LM; Fletcher M; Fiocchi A; Wagner AF; Fonseca J; Fokkens WJ; Forastiere F; Frith P; Gaga M; Gamkrelidze A; Garces J; Garcia-Aymerich J; Gemicioglu B; Gereda JE; Diaz SG; Gotua M; Grisle I; Grouse L; Gutter Z; Guzman MA; Heaney LG; Hellquist-Dahl B; Henderson D; Hendry A; Heinrich J; Heve D; Horak F; Hourihane JOB; Howarth P; Humbert M; Hyland ME; Illario M; Ivancevich JC; Jardim JR; Jares EJ; Jeandel C; Jenkins C; Johnston SL; Jonquet O; Julge K; Jung KS; Just J; Kaidashev I; Kaitov MR; Kalayci O; Kalyoncu AF; Keil T; Keith PK; Klimek L; N'Goran BK; Kolek V; Koppelman GH; Kowalski ML; Kull I; Kuna P; Kvedariene V; Lambrecht B; Lau S; Larenas-Linnemann D; Laune D; Le LTT; Lieberman P; Lipworth B; Li J; Carlsen KL; Louis R; MacNee W; Magard Y; Magnan A; Mahboub B; Mair A; Majer I; Makela MJ; Manning P; Mara S; Marshall GD; Masjedi MR; Matignon P; Maurer M; Mavale-Manuel S; Melen E; Melo-Gomes E; Meltzer EO; Menzies-Gow A; Merk H; Michel JP; Miculinic N; Mihaltan F; Milenkovic B; Mohammad GMY; Molimard M; Momas I; Montilla-Santana A; Morais-Almeida M; Morgan M; Mosges R; Mullol J; Nafti S; Namazova-Baranova L; Naclerio R; Neou A; Neffen H; Nekam K; Niggemann B; Ninot G; Nyembue TD; O'Hehir RE; Ohta K; Okamoto Y; Okubo K; Ouedraogo S; Paggiaro P; Pali-Scholl I; Panzner P; Papadopoulos N; Papi A; Park HS; Passalacqua G; Pavord I; Pawankar R; Pengelly R; Pfaar O; Picard R; Pigearias B; Pin I; Plavec D; Poethig D; Pohl W; Popov TA; Portejoie F; Potter P; Postma D; Price D; Rabe KF; Raciborski F; Pontal FR; Repka-Ramirez S; Reitamo S; Rennard S; Rodenas F; Roberts J; Roca J; Manas LR; Rolland C; Rodriguez MR; Romano A; Rosado-Pinto J; Rosario N; Rosenwasser L; Rottem M; Ryan D; Sanchez-Borges M; Scadding GK; Schunemann HJ; Serrano E; Schmid-Grendelmeier P; Schulz H; Sheikh A; Shields M; Siafakas N; Sibille Y; Similowski T; Simons FER; Sisul JC; Skrindo I; Smit HA; Sole D; Sooronbaev T; Spranger O; Stelmach R; Sterk PJ; Sunyer J; Thijs C; To T; Todo-Bom A; Triggiani M; Valenta R; Valero AL; Valia E; Valovirta E; Van Ganse E; van Hage M; Vandenplas O; Vasankari T; Vellas B; Vestbo J; Vezzani G; Vichyanond P; Viegi G; Vogelmeier C; Vontetsianos T; Wagenmann M; Wallaert B; Walker S; Wang DY; Wahn U; Wickman M; Williams DM; Williams S; Wright J; Yawn BP; Yiallouros PK; Yusuf OM; Zaidi A; Zar HJ; Zernotti ME; Zhang L; Zhong N; Zidarn M; Mercier J
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2016;279(2):205-207
Asthma phenotyping: noninvasive biomarkers suitable for bedside science are the next step to implement precision medicine
Dahlen S-E
Review: BRITISH JOURNAL OF PHARMACOLOGY. 2014;171(15):3551-3574
Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7
Back M; Powell WS; Dahlen S-E; Drazen JM; Evans JF; Serhan CN; Shimizu T; Yokomizo T; Rovati GE
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(2):475-478
Bitter taste receptor (TAS2R) agonists inhibit IgE-dependent mast cell activation
Ekoff M; Choi J-H; James A; Dahlen B; Nilsson G; Dahlen S-E
Editorial comment: NEW ENGLAND JOURNAL OF MEDICINE. 2014;370(22):2144-2145
TSLP in Asthma - A New Kid on the Block?
Dahlen S-E
Editorial comment: LANCET. 2014;383(9928):1608
Flushing, fatigue, and recurrent anaphylaxis: a delayed diagnosis of mastocytosis
Gulen T; Hagglund H; Dahlen S-E; Sander B; Dahlen B; Nilsson G
Letter: THORAX. 2013;68(11):1070-1071
The number needed to treat provides additional insight on the performance of detection points of asthma exacerbations in self-management plans: authors' response on behalf of the BIOAIR consortium
Kupczyk M; Dahlen S-E
Editorial comment: EUROPEAN RESPIRATORY JOURNAL. 2013;42(3):564-567
The European Respiratory Society fellowship programme: supporting young careers and building networks
Bals R; Yanmaz JR; Schaffter C; Pannetier C; Kamel N; Middelveld R; Dahlen S-E; Lambrecht BN; Nemery B; Nicod L; Holgate S
Review: EUROPEAN RESPIRATORY JOURNAL. 2013;42(3):802-825
Application of 'omics technologies to biomarker discovery in inflammatory lung diseases
Wheelock CE; Goss VM; Balgoma D; Nicholas B; Brandsma J; Skipp PJ; Snowden S; Burg D; D'Amico A; Horvath I; Chaiboonchoe A; Ahmed H; Ballereau S; Rossios C; Chung KF; Montuschi P; Fowler SJ; Adcock IM; Postle AD; Dahlen S-E; Rowe A; Sterk PJ; Auffray C; Djukanovic R
Review: IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA. 2013;33(3):329-viii
Refractoriness to Exercise Challenge A Review of the Mechanisms Old and New
Larsson J; Anderson SD; Dahlen S-E; Dahlen B
Review: BIOANALYSIS. 2012;4(18):2265-2290
Application of metabolomics approaches to the study of respiratory diseases
Snowden S; Dahlen S-E; Wheelock CE
Other: EUROPEAN RESPIRATORY JOURNAL. 2012;39(6):1283-1286
Prof. Andrzej Szczeklik, 1938-2012: aspirin-induced asthma and much more IN MEMORIAM
Dahlen S-E; Dahlen B; Rabe KF; Nizankowska-Mogilnicka E; Musial J; Sanak M; Gajewski P
Other: POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ. 2012;122:20-22
Professor Andrzej Szczeklik (1938-2012): a European intellectual defining aspirin-asthma and much more
Dahlen S-E; Dahlen B
Editorial comment: THORAX. 2011;66(12):1019-1020
Will recording of lung function fluctuation open the door to internet-guided treatment of asthma?
Kupczyk M; Dahlen S-E
Review: PHARMACOLOGICAL REVIEWS. 2011;63(3):539-584
International Union of Basic and Clinical Pharmacology. LXXXIV: Leukotriene Receptor Nomenclature, Distribution, and Pathophysiological Functions
Back M; Dahlen S-E; Drazen JM; Evans JF; Serhan CN; Shimizu T; Yokomizo T; Rovati GE
Review: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2011;24(4):361-366
Inflammation-induced airway smooth muscle responsiveness is strain dependent in mice
Safholm J; Lovdahl C; Swedin L; Boels PJM; Dahlen S-E; Arner A; Adner M
Review: CURRENT PHARMACEUTICAL BIOTECHNOLOGY. 2011;12(7):1026-1052
Lipid Mediator Profiling in Pulmonary Disease
Lundstrom SL; Balgoma D; Wheelock AM; Haeggstrom JZ; Dahlen S-E; Wheelock CE
Editorial comment: NEW ENGLAND JOURNAL OF MEDICINE. 2011;364(18):1769-1770
Asthma Treatment Guidelines Meet the Real World
Dahlen S-E; Dahlen B; Drazen JM
Review: POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ. 2011;121(12):456-459
Which anti-inflammatory drug should we use in asthma?
Kupczyk M; Dahlen B; Dahlen S-E
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2010;31(3):102-107
Dual COXIB/TP antagonists: a possible new twist in NSAID pharmacology and cardiovascular risk
Rovati GE; Sala A; Capra V; Dahlen S-E; Folco G
Review: ALLERGY. 2008;63(7):842-853
Important research questions in allergy and related diseases:: nonallergic rhinitis:: a GA²LEN paper
Bousquet J; Fokkens W; Burney P; Durham SR; Bachert C; Akdis CA; Canonica GW; Dahlen S-E; Zuberbier T; Bieber T; Bonini S; Bousquet PJ; Brozek JL; Cardell L-O; Crameri R; Custovic A; Demoly P; van Wijk RG; Gjomarkaj M; Holland C; Howarth P; Humbert M; Johnston SL; Kauffmann F; Kowalski ML; Lambrecht B; Lehmann S; Leynaert B; Lodrup-Carlsen K; Mullol J; Niggemann B; Nizankowska-Mogilnicka E; Papadopoulos N; Passalacqua G; Schuenemann HJ; Simon H-U; Todo-Bom A; Toskala E; Valenta R; Wickman M; Zock JP
Editorial comment: EUROPEAN RESPIRATORY JOURNAL. 2008;31(5):924-926
The Innovative Medicines Initiative (IMI): a new opportunity for scientific collaboration between academia and industry at the European level.
Kamel N; Compton C; Middelveld R; Higenbottam T; Dahlén S-E
Review: LAKARTIDNINGEN. 2007;104(39):2792-2796
[Costs of asthma and allergies to society unknown. Cost studies can give better planning of health care and research].
Jansson S-A; Arnlind MH; Dahlén S-E; Lundbäck B
Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;119(6):1337-1348
Severe asthma in adults: What are the important questions?
Chanez P; Wenzel SE; Anderson GP; Anto JM; Bel EH; Boulet L-P; Brightling CE; Busse WW; Castro M; Dahlen B; Dahlen SE; Fabbri LM; Holgate ST; Humbert M; Gaga M; Joos GF; Levy B; Rabe KF; Sterk PJ; Wilson SJ; Vachier I
Review: DRUG DISCOVERY TODAY. 2007;12(9-10):404-412
Pharmacological modulation of the leukotriene pathway in allergic airway disease
Montuschi P; Sala A; Dahlen S-E; Folco G
Review: ALLERGY. 2006;61(11):1249-1258
Tissue remodelling in upper airways: where is the link with lower airway remodelling?
Watelet J-B; Van Zele T; Gjomarkaj M; Canonica GW; Dahlen S-E; Fokkens W; Lund VJ; Scadding GK; Mullol J; Papadopoulos N; Bonini S; Kowalski ML; Van Cauwenberge P; Bousquet J
Review: PHARMACOLOGICAL REVIEWS. 2006;58(3):463-487
The lipoxin receptor ALX:: Potent ligand-specific and stereoselective actions in vivo
Chiang N; Serhan CN; Dahlen S-E; Drazen JM; Hay DWP; Rovati GE; Shimizu T; Yokomizo T; Brink C
Review: EUROPEAN JOURNAL OF PHARMACOLOGY. 2006;533(1-3):40-56
Treatment of asthma with antileukotrienes: First line or last resort therapy?
Dahlén SE
Editorial comment: THORAX. 2004;59(6):453-455
Monitoring mast cell activation by prostaglandin D₂ in vivo
Dahlèn SE; Kumlin M
Letter: EUROPEAN RESPIRATORY JOURNAL. 2004;23(3):492-493
The European Network for Understanding Mechanisms of Severe Asthma Study -: From the authors
Holgate ST; Dahlén SE
Review: PHARMACOLOGICAL REVIEWS. 2004;56(1):149-157
International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor
Brink C; Dahlén SE; Drazen J; Evans JF; Hay DWP; Rovati GE; Serhan CN; Shimizu T; Yokomizo T
Review: PHARMACOLOGICAL REVIEWS. 2003;55(1):195-227
International union of pharmacology - XXXVII. Nomenclature for leukotriene and lipoxin receptors
Brink C; Dahlen SE; Drazen J; Evans JF; Hay DWP; Nicosia S; Serhan CN; Shimizu T; Yokomizo T
Published conference paper: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2002;507:315-319
The contraction of the human pulmonary artery by LTC₄ is resistant to cysLT₁ antagonists and counteracted by prostacyclin release
Bäck M; Norel X; Walch L; Gascard JP; Dahlén SE; Brink C
Review: EUROPEAN RESPIRATORY JOURNAL. 2001;17(4):733-746
Health effects of diesel exhaust emissions
Sydbom A; Blomberg A; Parnia S; Stenfors N; Sandström T; Dahlén SE
Published conference paper: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2000;161(2):S41-S45
Pharmacological characterization of leukotriene receptors
Dahlén SE
Review: SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH. 2000;26:1-22
Particles in ambient air - a health risk assessment
Areskoug H; Camner P; Dahlén SE; Låstbom L; Nyberg F; Pershagen G; Sydbom A
Review: SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH. 2000;26 Suppl 1:28-38
Experimental studies on the effects of diesel exhaust emissions.
Sydbom A; Dahlén SE
Published conference paper: INFLAMMATION RESEARCH. 1999;48:S9-10
Selective effects of antileukotrienes on leukotriene and histamine release in human dispersed lung cells
Larsson L; Sydbom A; Dahlén SE
Review: CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY. 1999;17(1-2):179-191
Leukotriene receptors
Dahlén SE
Review: JOURNAL OF INTERNAL MEDICINE. 1999;245(3):205-227
Asthma and leukotrienes: antileukotrienes as novel anti-asthmatic drugs
Claesson HE; Dahlén SE
Published conference paper: CLINICAL AND EXPERIMENTAL ALLERGY. 1998;28:141-146
Lipid mediator pathways in the lung: leukotrienes as a new target for the treatment of asthma
Dahlén SE
Published conference paper: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 1998;157(4):1187-1194
Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics
Dahlén B; Nizankowska E; Szczeklik A; Zetterström O; Bochenek G; Kumlin M; Mastalerz L; Pinis G; Swanson LJ; Boodhoo TI; Wright S; Dubé LM; Dahlén SE
Editorial comment: CLINICAL AND EXPERIMENTAL ALLERGY. 1998;28(2):129-133
Can asthma be studied in the urine?
Dahlén SE; Kumlin M
Published conference paper: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 1997;155(6):1856-1863
Combined antagonism of leukotrienes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics
Roquet A; Dahlen B; Kumlin M; Ihre E; Anstren G; Binks S; Dahlen SE
Published conference paper: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 1997;433:375-378
Leukotriene A₄ hydrolase activity in Xenopus laevis
Strömberg F; Rosenqvist U; Dahlén SE; Haeggström JZ
Published conference paper: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 1997;433:159-162
Urinary 9α, 11β-PGF₂ as a marker of mast cell activation in allergic and aspirin-intolerant asthma
O'Sulliván S; Dahlén B; Roquet A; Larsson L; Dahlén SE; Kumlin M
Editorial comment: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1996;98(5):S105-S106
Chloride transport and the actions of nedocromil sodium and cromolyn sodium in asthma - Discussion
Barnes PJ; Paulmichl M; Dahlen SE; Seale JP; Alton EWFW; Lee TH; Norris AA; Holgate ST
Published conference paper: CLINICAL AND EXPERIMENTAL ALLERGY. 1995;25:50-54
LEUKOTRIENES AS MEDIATORS OF AIRWAY-OBSTRUCTION AND INFLAMMATION IN ASTHMA
DAHLEN B; DAHLEN SE
Review: ADVANCES IN PROSTAGLANDIN, THROMBOXANE, AND LEUKOTRIENE RESEARCH. 1995;23:353-355
LEUKOTRIENES AND OTHER MEDIATORS OF THE SCHULTZ-DALE REACTION IN GUINEA-PIG LUNG PARENCHYMA
JONSSON EW; DAHLEN SE
Review: ADVANCES IN PROSTAGLANDIN, THROMBOXANE, AND LEUKOTRIENE RESEARCH. 1995;23:283-285
PROSTANOID AND LEUKOTRIENE RECEPTORS - A PROGRESS REPORT FROM THE IUPHAR WORKING PARTIES ON CLASSIFICATION AND NOMENCLATURE
COLEMAN RA; EGLEN RM; JONES RL; NARUMIYA S; SHIMIZU T; SMITH WL; DAHLEN SE; DRAZEN JM; GARDINER PJ; JACKSON WT; JONES TR; KRELL RD; NICOSIA S
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Professor, Senior, Department of Medicine, Huddinge, Karolinska Institutet, 2024-2025
Professor, Department of Medicine, Huddinge, Karolinska Institutet, 2024-2024

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