Suhas Darekar

Publications
CV
Public outreach and news

Articles

Article: CELL DEATH DISCOVERY. 2022;8(1):464
Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells
Alkasalias T; Zhang J; Madapura H; Dalarun B; Reina OB; Lewensohn R; Viktorsson K; Salihi A; Darekar S; Lain S
Article: ISCIENCE. 2021;24(5):102494
DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance
Zhang J; Teran G; Popa M; Madapura H; Ladds MJGW; Lianoudaki D; Grunler J; Arsenian-Henriksson M; McCormack E; Rottenberg ME; Catrina S-B; Lain S; Darekar S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(27):15673-15683
Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2
Mushtaq M; Kovalevska L; Darekar S; Abramsson A; Zetterberg H; Kashuba V; Klein G; Arsenian-Henriksson M; Kashuba E
Article: NATURE COMMUNICATIONS. 2018;9(1):1107
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Fernandez AP; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Farnegardh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Hakansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Lain S
Article: ONCOTARGET. 2017;8(39):64907-64917
Rat embryonic fibroblasts immortalized by MRPS18-2 protein are target for NK-cells
Mushtaq M; Pangigadde PN; Darekar S; Dissen E; Kashuba E
Article: ONCOTARGET. 2015;6(25):21016-21028
Mitochondrial ribosomal protein S18-2 evokes chromosomal instability and transforms primary rat skin fibroblasts
Darekar SD; Mushtaq M; Gurrapu S; Kovalevska L; Drummond C; Petruchek M; Tirinato L; Di Fabrizio E; Carbone E; Kashuba E
Article: PLOS ONE. 2015;10(8):e0136142
Different Mechanisms of Regulation of the Warburg Effect in Lymphoblastoid and Burkitt Lymphoma Cells
Mushtaq M; Darekar S; Klein G; Kashuba E
Article: ACTA NATURAE. 2013;5(1):85-89
Overexpression of MRPS18-2 in Cancer Cell Lines Results in Appearance of Multinucleated Cells
Shevchuk Z; Yurchenko MY; Darekar SD; Holodnuka-Kholodnyuk I; Kashuba VI; Kashuba EV
Article: THE ANALYST. 2012;137(16):3767-3772
Analysis of protein-protein interactions in a complex environment: capture of an analyte-receptor complex with standard additions of the receptor (CARSAR) approach
Snopok BA; Darekar S; Kashuba EV
Article: CELL DEATH AND DISEASE. 2012;3(1):e357
Stem cell gene expression in MRPS18-2-immortalized rat embryonic fibroblasts
Yenamandra SP; Darekar SD; Kashuba V; Matskova L; Klein G; Kashuba E
Article: PLOS ONE. 2012;7(7):e42072
Epstein-Barr Virus Immortalization of Human B-Cells Leads to Stabilization of Hypoxia-Induced Factor 1 Alpha, Congruent with the Warburg Effect
Darekar S; Georgiou K; Yurchenko M; Yenamandra SP; Chachami G; Simos G; Klein G; Kashuba E
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2010;67(24):4249-4256
Epstein-Barr virus encoded EBNA-3 binds to vitamin D receptor and blocks activation of its target genes
Yenamandra SP; Hellman U; Kempkes B; Darekar SD; Petermann S; Sculley T; Klein G; Kashuba E
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(47):19866-19871
MRPS18-2 protein immortalizes primary rat embryonic fibroblasts and endows them with stem cell-like properties
Kashuba E; Yenamandra SP; Darekar SD; Yurchenko M; Kashuba V; Klein G; Szekely L

All other publications

Corrigendum: CELL DEATH DISCOVERY. 2022;8(1):472
Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells (vol 15, pg 548, 2022)
Alkasalias T; Zhang J; Madapura H; Dalarun B; Reina OB; Lewensohn R; Viktorsson K; Salihi A; Darekar S; Lain S
Corrigendum: NATURE COMMUNICATIONS. 2018;9(1):2071
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Fernandez AP; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Farnegardh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Hakansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Lain S
Review: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2016;2016:6468342
DNA Tumor Viruses and Cell Metabolism
Mushtaq M; Darekar S; Kashuba E
Thesis / dissertation: 2013
The role of EBNA binding proteins in cell transformation
Darekar, Suhas

Employments

Senior Research Specialist, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2019-

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2014

Articles

All other publications

Employments

Degrees and Education

News from KI

Events from KI