Sofia Berglund

About me
Publications
CV
Public outreach and news

About me

I am a medical doctor and researcher interested in immunology, stem cell
transplantation, hematology and cancer.
MD, Medical Degree 2008 at KI, Medical License 2012.
PhD at KI 2014

Research

I work with translational research associated with the development of an
autologous T cell immunotherapy for solid cancer based on neoantigen
technology. Currently, my team is planning a clinical first-in-human trial of
our T cell product, pTTL, starting during 2022.

Articles

Article: VOX SANGUINIS. 2019;114(7):769-777
Granulocyte transfusions could benefit patients with severe oral mucositis after allogeneic hematopoietic stem cell transplantation
Berglund S; Watz E; Remberger M; Legert KG; Axdorph-Nygell U; Sundin M; Uhlin M; Mattsson J
Article: JCI INSIGHT. 2018;3(21):120974
Signatures of CD8⁺ T cell dysfunction in AML patients and their reversibility with response to chemotherapy
Knaus HA; Berglund S; Hackl H; Blackford AL; Zeidner JF; Montiel-Esparza R; Mukhopadhyay R; Vanura K; Blazar BR; Karp JE; Luznik L; Gojo I
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2018;194(1):39-53
Tissue-resident memory T cells are epigenetically cytotoxic with signs of exhaustion in human urinary bladder cancer
Hartana CA; Bergman EA; Broome A; Berglund S; Johansson M; Alamdari F; Jakubczyk T; Huge Y; Aljabery F; Palmqvist K; Holmstrom B; Glise H; Riklund K; Sherif A; Winqvist O
Article: CLINICAL EPIGENETICS. 2018;10(1):102
Increased CD4⁺ T cell lineage commitment determined by CpG methylation correlates with better prognosis in urinary bladder cancer patients
Bergman EA; Hartana CA; Johansson M; Linton LB; Berglund S; Hyllienmark M; Lundgren C; Holmstrom B; Palmqvist K; Hansson J; Alamdari F; Huge Y; Aljabery F; Riklund K; Winerdal ME; Krantz D; Zirakzadeh AA; Marits P; Sjoholm LK; Sherif A; Winqvist O
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2018;24(4):666-677
Increased Coexpression of PD-1, TIGIT, and KLRG-1 on Tumor-Reactive CD8+ T Cells During Relapse after Allogeneic Stem Cell Transplantation.
Hutten TJA; Norde WJ; Woestenenk R; Wang RC; Maas F; Kester M; Falkenburg JHF; Berglund S; Luznik L; Jansen JH; Schaap N; Dolstra H; Hobo W
Article: BLOOD. 2018;131(2):247-262
NK cell recovery after haploidentical HSCT with posttransplant cyclophosphamide: dynamics and clinical implications.
Russo A; Oliveira G; Berglund S; Greco R; Gambacorta V; Cieri N; Toffalori C; Zito L; Lorentino F; Piemontese S; Morelli M; Giglio F; Assanelli A; Stanghellini MTL; Bonini C; Peccatori J; Ciceri F; Luznik L; Vago L
Article: STEM CELLS INTERNATIONAL. 2018;2018:8529104-15
Expansion of Gammadelta T Cells from Cord Blood: A Therapeutical Possibility
Berglund S; Gaballa A; Sawaisorn P; Sundberg B; Uhlin M
Article: CYTOTHERAPY. 2014;16(11):1528-1536
Expanded umbilical cord blood T cells used as donor lymphocyte infusions after umbilical cord blood transplantation
Berglund S; Gertow J; Uhlin M; Mattsson J
Article: JOURNAL OF IMMUNOTHERAPY. 2013;36(8):432-441
Cord Blood T Cells Cultured With IL-7 in Addition to IL-2 Exhibit a Higher Degree of Polyfunctionality and Superior Proliferation Potential
Berglund S; Gertow J; Magalhaes I; Mattsson J; Uhlin M
Article: CHIMERISM. 2013;4(1):34-35
Chimerism and use of mesenchymal stem cells in umbilical cord blood transplantation.
Berglund S; Uhlin M; Mattsson J
Article: TRANSPLANTATION. 2012;94(10):1066-1074
Factors With an Impact on Chimerism Development and Long-Term Survival After Umbilical Cord Blood Transplantation
Berglund S; Le Blanc K; Remberger M; Gertow J; Uzunel M; Svenberg P; Winiarski J; Ljungman P; Ringden O; Uhlin M; Mattsson J
Article: CLINICAL INFECTIOUS DISEASES. 2012;55(8):1064-1073
Rapid Salvage Treatment With Virus-Specific T Cells for Therapy-Resistant Disease
Uhlin M; Gertow J; Uzunel M; Okas M; Berglund S; Watz E; Brune M; Ljungman P; Maeurer M; Mattsson J
Article: STEM CELLS AND DEVELOPMENT. 2012;21(9):1409-1417
Mesenchymal Stem Cells Inhibit Thymic Reconstitution After Allogeneic Cord Blood Transplantation
Uhlin M; Sairafi D; Berglund S; Thunberg S; Gertow J; Ringden O; Uzunel M; Remberger M; Mattsson J
Article: CLINICAL IMMUNOLOGY. 2012;143(2):134-144
Expansion of T-cells from the cord blood graft as a predictive tool for complications and outcome of cord blood transplantation
Gertow J; Berglund S; Okas M; Karre K; Remberger M; Mattsson J; Uhlin M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(11):1688-1697
Improved Survival after Allogeneic Hematopoietic Stem Cell Transplantation in Recent Years. A Single-Center Study
Remberger M; Ackefors M; Berglund S; Blennow O; Dahllof G; Dlugosz A; Garming-Legert K; Gertow J; Gustafsson B; Hassan M; Hassan Z; Hauzenberger D; Hagglund H; Karlsson H; Klingspor L; Kumlien G; Le Blanc K; Ljungman P; Machaczka M; Malmberg K-J; Marschall H-U; Mattsson J; Olsson R; Omazic B; Sairafi D; Schaffer M; Svahn B-M; Svenberg P; Swartling L; Szakos A; Uhlin M; Uzunel M; Watz E; Wernerson A; Wikman A; Wikstrom A-C; Winiarski J; Ringden O
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2010;162(1):146-155
Characterization of long-term mixed donor-donor chimerism after double cord blood transplantation
Gertow J; Berglund S; Okas M; Uzunel M; Berg L; Karre K; Mattsson J; Uhlin M
Article: INTERNATIONAL JOURNAL OF HEMATOLOGY. 2009;90(4):526-531
Stable mixed donor-donor chimerism after double cord blood transplantation
Berglund S; Okas M; Gertow J; Uhlin M; Mattsson J

All other publications

Review: EXPERT OPINION ON BIOLOGICAL THERAPY. 2019;19(8):811-827
Facing the future: challenges and opportunities in adoptive T cell therapy in cancer.
Magalhaes I; Carvalho-Queiroz C; Hartana CA; Kaiser A; Lukic A; Mints M; Nilsson O; Grönlund H; Mattsson J; Berglund S
Review: EXPERT OPINION ON BIOLOGICAL THERAPY. 2017;17(6):691-699
Advances in umbilical cord blood cell therapy: the present and the future
Berglund S; Magalhaes I; Gaballa A; Vanherberghen B; Uhlin M
Meeting abstract: BLOOD. 2016;128(22):4567
Natural Killer Cell Reconstitution after Haploidentical Hematopoietic Stem Cell Transplantation with Post-Transplant Cyclophosphamide: Elimination of Donor-Derived Mature Alloreactive NK Cells, but Favorable Conditions for Adoptive Immunotherapy
Russo A; Oliveira G; Berglund S; Greco R; Gambacorta V; Cieri N; Toffalori C; Zito L; Piemontese S; Morelli M; Giglio F; Assanelli AA; Stanghellini MTL; Bonini C; Peccatori J; Luznik L; Ciceri F; Vago L
Thesis / dissertation: 2014
Umbilical cord blood transplantation : clinical outcome, chimerism development, and in vitro expansion of T-cells for clinical use
Berglund, Sofia

Employments

Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2014
University Medical Degree, Karolinska Institutet, 2008

About me

Research

Articles

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Employments

Degrees and Education

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