Simona Sacuiu

Publications
Public outreach and news

Articles

Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2024;79(2):glad216

Biomarkers of Alzheimer's Disease and Cerebrovascular Disease in Relation to Depressive Symptomatology in Individuals With Subjective Cognitive Decline

Zapater-Fajari M; Diaz-Galvan P; Cedres N; Sterner TR; Ryden L; Sacuiu S; Waern M; Zettergren A; Zetterberg H; Blennow K; Kern S; Hidalgo V; Salvador A; Westman E; Skoog I; Ferreira D
Article: ALZHEIMER'S AND DEMENTIA: DIAGNOSIS, ASSESSMENT AND DISEASE MONITORING. 2024;16(1):e12556

Association of CSF biomarkers with MRI brain changes in Alzheimer's disease

Seidu NM; Kern S; Sacuiu S; Sterner TR; Blennow K; Zetterberg H; Lindberg O; Ferreira D; Westman E; Zettergren A; Skoog I
Article: BMJ OPEN. 2023;13(10):e072803

Longstanding smoking associated with frontal brain lobe atrophy: a 32-year follow-up study in women.

Johansson L; Guo X; Sacuiu S; Fässberg MM; Kern S; Zettergren A; Skoog I
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2023;148(1):91-101

Mild cognitive impairment is associated with passive suicidal ideation in older adults: A population-based study

Rymo I; Fassberg MM; Kern S; Zetterberg H; Skoog I; Waern M; Sacuiu S
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2023;78(6):1069-1077

Decreasing Incidence and Prevalence of Dementia Among Octogenarians: A Population-Based Study on 3 Cohorts Born 30 Years Apart

Wetterberg H; Najar J; Sterner TR; Ryden L; Erhag HF; Sacuiu S; Kern S; Zettergren A; Skoog I
Article: JAMA NEUROLOGY. 2023;80(6):548-557

Clinical Effect of Early vs Late Amyloid Positron Emission Tomography in Memory Clinic Patients The AMYPAD-DPMS Randomized Clinical Trial

Altomare D; Barkhof F; Caprioglio C; Collij LE; Scheltens P; Lopes Alves I; Bouwman F; Berkhof J; van Maurik IS; Garibotto V; Moro C; Delrieu J; Payoux P; Saint-Aubert L; Hitzel A; Molinuevo JL; Grau-Rivera O; Gispert JD; Drzezga A; Jessen F; Zeyen P; Nordberg A; Savitcheva I; Jelic V; Walker Z; Edison P; Demonet J-F; Gismondi R; Farrar G; Stephens AW; Frisoni GB
Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S2)

Associations between cerebrospinal fluid biomarkers and brain regions of relevance for very early Alzheimer’s disease processes

Seidu NM; Kern S; Sacuiu S; Sterner TR; Blennow K; Zetterberg H; Lindberg O; Ferreira D; Westman E; Zettergren A; Skoog I
Article: JOURNAL OF ALZHEIMERS DISEASE. 2023;91(3):1165-1171

Screening for Mild Cognitive Impairment Using a Machine Learning Classifier and the Remote Speech Biomarker for Cognition: Evidence from Two Clinically Relevant Cohorts.

Schäfer S; Mallick E; Schwed L; König A; Zhao J; Linz N; Bodin TH; Skoog J; Possemis N; Ter Huurne D; Zettergren A; Kern S; Sacuiu S; Ramakers I; Skoog I; Tröger J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2023;91(1):291-303

Subtle Differences in Cognition in 70-Year-Olds with Elevated Cerebrospinal Fluid Neurofilament Light and Neurogranin: A H70 Cross-Sectional Study

Radestig MA; Skoog J; Zetterberg H; Skillback T; Zettergren A; Sterner TR; Fassberg MM; Sacuiu S; Waern M; Wetterberg H; Blennow K; Skoog I; Kern S
Article: JAMA NETWORK OPEN. 2023;6(1):e2250921

Analysis of Psychological Symptoms Following Disclosure of Amyloid-Positron Emission Tomography Imaging Results to Adults With Subjective Cognitive Decline

Caprioglio C; Ribaldi F; Visser LNC; Minguillon C; Collij LE; Grau-Rivera O; Zeyen P; Molinuevo JL; Domingo Gispert J; Garibotto V; Moro C; Walker Z; Edison P; Demonet J-F; Barkhof F; Scheltens P; Alves IL; Gismondi R; Farrar G; Stephens AW; Jessen F; Frisoni GB; Altomare D
Article: FRONTIERS IN EPIDEMIOLOGY. 2023;3:1151519

Attrition in the Gothenburg H70 birth cohort studies, an 18-year follow-up of the 1930 cohort.

Rydén L; Wetterberg H; Ahlner F; Falk Erhag H; Gudmundsson P; Guo X; Joas E; Johansson L; Kern S; Mellqvist Fässberg M; Najar J; Ribbe M; Rydberg Sterner T; Sacuiu S; Samuelsson J; Sigström R; Skoog J; Waern M; Zettergren A; Skoog I
Article: BMJ OPEN. 2022;12(12):e068165

Representativeness in population-based studies of older adults: five waves of cross-sectional examinations in the Gothenburg H70 Birth Cohort Study

Wetterberg H; Ryden L; Ahlner F; Falk Erhag H; Gudmundsson P; Guo X; Joas E; Johansson L; Kern S; Fassberg MM; Najar J; Ribbe M; Sterner TR; Samuelsson J; Sacuiu S; Sigstrom R; Skoog J; Waern M; Zettergren A; Skoog I
Article: ALZHEIMERS & DEMENTIA. 2022;18(9):1667-1676

Slowing gait speed precedes cognitive decline by several years.

Skillbäck T; Blennow K; Zetterberg H; Skoog J; Rydén L; Wetterberg H; Guo X; Sacuiu S; Mielke MM; Zettergren A; Skoog I; Kern S
Article: INTERNATIONAL PSYCHOGERIATRICS. 2022;34(5):479-488

Accuracy of 12 short versions of the Geriatric Depression Scale to detect depression in a prospective study of a high-risk population with different levels of cognition.

Sacuiu S; Seidu NM; Sigström R; Rydberg Sterner T; Johansson L; Wiktorsson S; Waern M
Article: NEUROLOGY. 2021;97(16):e1608-e1619

Atrial Fibrillation, Stroke, and Silent Cerebrovascular Disease A Population-based MRI Study

Ryden L; Sacuiu S; Wetterberg H; Najar J; Guo X; Kern S; Zettergren A; Shams S; Pereira JB; Wahlund L-O; Westman E; Skoog I
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2021;36(5):507-517

Dementia remains the major predictor of death among octogenarians. A study of two population cohorts of 85-year-olds examined 22 years apart

Wetterberg H; Najar J; Ryden L; Ribbe M; Rydberg Sterner T; Zettergren A; Guo X; Falk Erhag H; Sacuiu S; Kern S; Skoog I
Article: NEUROBIOLOGY OF AGING. 2021;101:1-12

Effects of amyloid pathology and the APOE ε4 allele on the association between cerebrospinal fluid Aβ38 and Aβ40 and brain morphology in cognitively normal 70-years-olds

Lindberg O; Kern S; Skoog J; Machado A; Pereira JB; Sacuiu SF; Wahlund L-O; Blennow K; Zetterberg H; Zettergren A; Westman E; Skoog I
Article: JOURNAL OF ALZHEIMERS DISEASE. 2021;79(1):225-235

Cognitive Performance and Cerebrospinal Fluid Markers in Preclinical Alzheimer's Disease: Results from the Gothenburg H70 Birth Cohort Studies.

Rådestig MA; Skoog J; Zetterberg H; Kern J; Zettergren A; Sacuiu S; Waern M; Wetterberg H; Blennow K; Skoog I; Kern S
Journal article: ALZHEIMERS & DEMENTIA. 2020;16(S10)

Atrial fibrillation and the interaction with stroke in relation to white matter lesion volumes: A population‐based study in 70‐year‐olds

Rydén L; Sacuiu S; Wetterberg H; Najar J; Zettergren A; Kern S; Pereira JB; Wahlund L; Westman E; Skoog I
Article: AGING-US. 2020;12(1):894-901

Predicting Fazekas scores from automatic segmentations of white matter signal abnormalities

Cedres N; Ferreira D; Machado A; Shams S; Sacuiu S; Waern M; Wahlund L-O; Zettergren A; Kern S; Skoog I; Westman E
Article: NEUROBIOLOGY OF AGING. 2019;80:111-115

Longstanding psychological stress in relation to biomarkers of neuronal dysfunction in cerebrospinal fluid: a 25-year follow-up study in women.

Johansson L; Sacuiu S; Kern S; Guo X; Zetterberg H; Blennow K; Zettergren A; Skoog I
Article: JOURNAL OF INTERNAL MEDICINE. 2019;286(1):101-110

Atrial fibrillation increases the risk of dementia amongst older adults even in the absence of stroke.

Rydén L; Zettergren A; Seidu NM; Guo X; Kern S; Blennow K; Zetterberg H; Sacuiu S; Skoog I
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2019;34(2):191-209

The Gothenburg H70 Birth cohort study 2014-16: design, methods and study population

Sterner TR; Ahlner F; Blennow K; Dahlin-Ivanoff S; Falk H; Johansson LH; Hoff M; Holm M; Horder H; Jacobsson T; Johansson B; Johansson L; Kern J; Kern S; Machado A; Fassberg MM; Nilsson J; Ribbe M; Rothenberg E; Ryden L; Sadeghi A; Sacuiu S; Samuelsson J; Sigstrom R; Skoog J; Thorvaldsson V; Waern M; Westman E; Wetterberg H; Zetterberg H; Zetterberg M; Zettergren A; Ostling S; Skoog I
Article: JOURNAL OF ALZHEIMERS DISEASE. 2018;66(2):483-495

Increased Risk of Dementia in Subjective Cognitive Decline if CT Brain Changes are Present.

Sacuiu S; Eckerström M; Johansson L; Kern S; Sigström R; Xinxin G; Östling S; Skoog I
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2018;33(10):1305-1311

Chronic depressive symptomatology and CSF amyloid beta and tau levels in mild cognitive impairment

Gonzales MM; Insel PS; Nelson C; Tosun D; Schoell M; Mattsson N; Sacuiu S; Bickford D; Weiner MW; Mackin RS
Article: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY. 2017;25(9):980-991

Cortical Atrophy is Associated with Accelerated Cognitive Decline in Mild Cognitive Impairment with Subsyndromal Depression.

Gonzales MM; Insel PS; Nelson C; Tosun D; Mattsson N; Mueller SG; Sacuiu S; Bickford D; Weiner MW; Mackin RS; Alzheimer's Disease Neuroimaging Initiative
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;58(2):537-547

Modifiable Risk Factors for Prevention of Dementia in Midlife, Late Life and the Oldest-Old: Validation of the LIBRA Index

Vos SJB; van Boxtel MPJ; Schiepers OJG; Deckers K; de Vugt M; Carriere I; Dartigues J-F; Peres K; Artero S; Ritchie K; Galluzzo L; Scafato E; Frison GB; Huisman M; Comijs HC; Sacuiu SF; Skoog I; Irving K; O'Donnell CA; Verhey FRJ; Visser PJ; Kohler S
Article: ALZHEIMER'S AND DEMENTIA: DIAGNOSIS, ASSESSMENT AND DISEASE MONITORING. 2017;8:96-107

Longitudinal evaluation of criteria for subjective cognitive decline and preclinical Alzheimer's disease in a memory clinic sample.

Eckerström M; Göthlin M; Rolstad S; Hessen E; Eckerström C; Nordlund A; Johansson B; Svensson J; Jonsson M; Sacuiu S; Wallin A
Article: JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY. 2016;29(3):133-141

Cognitive Function in Older Suicide Attempters and a Population-Based Comparison Group.

Olsson P; Wiktorsson S; Sacuiu S; Marlow T; Östling S; Fässberg MM; Skoog I; Waern M
Article: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY. 2016;24(2):126-135

Chronic Depressive Symptomatology in Mild Cognitive Impairment Is Associated with Frontal Atrophy Rate which Hastens Conversion to Alzheimer Dementia.

Sacuiu S; Insel PS; Mueller S; Tosun D; Mattsson N; Jack CR; DeCarli C; Petersen R; Aisen PS; Weiner MW; Mackin RS; Alzheimer's Disease Neuroimaging Initiative
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2016;42(1-2):93-105

High Prevalence of Stress and Low Prevalence of Alzheimer Disease CSF Biomarkers in a Clinical Sample with Subjective Cognitive Impairment.

Eckerström M; Berg AI; Nordlund A; Rolstad S; Sacuiu S; Wallin A
Article: PSYCHOLOGY AND AGING. 2012;27(2):375-383

Nonlinear blood pressure effects on cognition in old age: separating between-person and within-person associations.

Thorvaldsson V; Skoog I; Hofer SM; Börjesson-Hanson A; Ostling S; Sacuiu S; Johansson B
Journal article: ALZHEIMERS & DEMENTIA. 2011;7(4S_Part_17):s591

P3‐236: Development of a clinical risk score for predicting dementia in the DESCRIPA project (European pooled data base) and validation in the three‐city study

Artero S; van Boxtel M; Dartigues J; Deeg D; Dick M; Frisoni G; Galluzzo L; Jolles J; Jonker C; Luck T; Peres K; Riedel‐Heller S; Ritchie K; Carrière I; Berr C; Sacuiu S; Scafato E; Skoog I; Schoevers R; Verhey FRJ; Visser P
Article: JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY. 2011;17(1):154-162

Onset and Rate of Cognitive Change Before Dementia Diagnosis: Findings From Two Swedish Population-Based Longitudinal Studies

Thorvaldsson V; MacDonald SWS; Fratiglioni L; Winblad B; Kivipelto M; Laukka EJ; Skoog I; Sacuiu S; Guo X; Ostling S; Borjesson-Hanson A; Gustafson D; Johansson B; Backman L
Article: NEUROLOGY. 2010;75(9):779-785

Secular changes in cognitive predictors of dementia and mortality in 70-year-olds

Sacuiu S; Gustafson D; Sjogren M; Guo X; Ostling S; Johansson B; Skoog I
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2009;24(12):1413-1419

The prevalence of psychotic symptoms and paranoid ideation in non-demented population samples aged 70-82 years.

Sigström R; Skoog I; Sacuiu S; Karlsson B; Klenfeldt IF; Waern M; Gustafson D; Ostling S
Article: ALZHEIMERS & DEMENTIA. 2009;5(3):199-206

The pattern of cognitive symptoms predicts time to dementia onset

Sacuiu S; Gustafson D; Johansson B; Thorvaldsson V; Berg S; Sjogren M; Guo X; Ostling S; Skoog I
Article: NEUROLOGY. 2008;71(12):882-887

Onset of terminal decline in cognitive abilities in individuals without dementia.

Thorvaldsson V; Hofer SM; Berg S; Skoog I; Sacuiu S; Johansson B
Journal article: ALZHEIMERS & DEMENTIA. 2008;4(4S_Part_20):t667-t668

P4‐004: Risk factors for progression to dementia in general population: The diagnostic criteria for predementia Alzheimer's disease (Descripa) study (European pooled data base)

Artero S; van Boxtel M; Dartigues J-F; Deeg D; Dick M; Frisoni G; Galluzzo L; Jolles J; Jonker C; Luck T; Peres K; Riedel-Heller S; Ritchie K; Sacuiu S; Scafato E; Skoog I; Schoevers R; Verhey F; Visser PJ
Article: NEUROLOGY. 2005;65(12):1894-1900

Prodromal cognitive signs of dementia in 85-year-olds using four sources of information.

Sacuiu S; Sjögren M; Johansson B; Gustafson D; Skoog I
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Corrigendum: JOURNAL OF ALZHEIMERS DISEASE. 2019;71(2):713

Increased Risk of Dementia in Subjective Cognitive Decline if CT Brain Changes are Present.
Review: HANDBOOK OF CLINICAL NEUROLOGY. 2016;138:123-151

Dementias.

Sacuiu SF
Editorial comment: NEUROLOGY. 2011;76(10):879-886

A population-based study on the influence of brain atrophy on 20-year survival after age 85.

Olesen PJ; Guo X; Gustafson D; Börjesson-Hanson A; Sacuíu S; Eckerström C; Bigler ED; Skoog I

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