Shanie Saghafian-Hedengren

Shanie Saghafian-Hedengren

Affiliated to Research
Visiting address: BioMedicum A4, Solnavägen 9, 17165 Solna
Postal address: K6 Kvinnors och barns hälsa, K6 Barnonkologi och Barnkirurgi Nilsson, 171 77 Stockholm
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Research

  • *RECOVERY OF THE IMMUNE SYSTEM AND RESISTANCE AGAINST INFECTIONS IN
    PAEDIATRIC PATIENTS UNDERGOING CHEMOTHERAPY. *The overall vision with our
    research is to provide an optimal life quality – in terms of resistance to
    infections – for children that have undergone or are undergoing treatment
    against cancers.* *To this end, our in vivo and in vitro projects
    examine in detail how cell cytotoxic treatments influence children’s immune
    responses to infectious agents. Both during an acute state, while the
    treatment is ongoing, as well as during long-term, after cessation of
    chemotherapy. Through further collaborations, we investigate how the recovery
    of the immune system and its functions, as well as chemotherapy efficacy
    itself, are influenced by the gut microbiome. In addition, in order to
    broaden and update our knowledge about infections among the paediatric
    population in Sweden, our ongoing clinical research projects assess
    vaccination coverage, and the prevalence and type of infections, in healthy
    children and children with underling comorbidities.
    For detailed information visit:
    /https://ki.se/en/kbh/recovery-of-the-immune-system-and-resistance-against-infections-in-paediatric-patients/

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