Sebastian Bjöhle

I am a prehospital emergency nurse and a clinical doctoral student in medical science at the Department of Clinical Science and Education at Södersjukhuset (KI SÖS). My clinical background includes several years in both cardiac intensive care and emergency medical service – two environments that have shaped my commitment to acute cardiac care and my research interest in the early identification of patients suffering from myocardial infarction.

Chest pain is one of the most common symptoms among patients in prehospital emergency care. However, it is often challenging to identify which patients are actually experiencing an acute myocardial infarction, especially when no clear ECG changes are present. This clinical uncertainty and the risk of treatment delays form the foundation of my doctoral project, which focuses on early identification and clinical decision-making in patientes with myocardial infarction.

I also serve as a lecturer and course coordinator in the specialist nursing programme in ambulance care at Karolinska Institutet. Contributing to the education of future prehospital emergency nurses is, to me, both meaningful and inspiring. It allows me to integrate pedagogy, research, and clinical experience – while also supporting the development of prehospital emergency care.

Research

My research aims to improve the prehospital management of patients with myocardial infarction, with a particular focus on early identification and clinical decision-making.

A central component of my doctoral project is the randomized controlled trial TIGER (The effect of high-sensitivity Troponin I in addition to guideline-based care to identify myocardial infarction in prehospital emergency care – an open-label randomized controlled trial). The study investigates whether a novel point-of-care high-sensitivity troponin I test, used alongside standard prehospital care, can enable earlier identification, faster treatment, and improved outcomes. We are among the first in the world to evaluate the clinical utility of high-sensitivity troponin testing in a prehospital setting.

My principal supervisor is Jakob Lederman (PhD, Karolinska Institutet), and my co-supervisor is Veronica Vicente (Associate Professor, Karolinska Institutet). The project is conducted in collaboration with Ambulanssjukvården i Storstockholm AB (AISAB) and has received competitive research funding from Nätverkssjukvården (NSV) in Region Stockholm for the years 2024 and 2025.