Sarah Thomas Broome

Publications
Grants
CV
Public outreach and news

Articles

Journal article: JOURNAL OF NEUROCHEMISTRY. 2024;168(9):3250-3267
Targeting the PAC1 receptor mitigates degradation of myelin and synaptic markers and diminishes locomotor deficits in the cuprizone demyelination model.
Jansen MI; Mahmood Y; Lee J; Broome ST; Waschek JA; Castorina A
Journal article: INTERNATIONAL JOURNAL OF TRYPTOPHAN RESEARCH. 2024;17:11786469241248287
A Review of the Evidence for Tryptophan and the Kynurenine Pathway as a Regulator of Stem Cell Niches in Health and Disease.
Summers BS; Thomas Broome S; Pang TWR; Mundell HD; Koh Belic N; Tom NC; Ng ML; Yap M; Sen MK; Sedaghat S; Weible MW; Castorina A; Lim CK; Lovelace MD; Brew BJ
Journal article: JOURNAL OF MOLECULAR NEUROSCIENCE. 2023;73(9-10):724-737
Early Alterations of PACAP and VIP Expression in the Female Rat Brain Following Spinal Cord Injury.
Broome ST; Mandwie M; Gorrie CA; Musumeci G; Marzagalli R; Castorina A
Journal article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(13):11118
Altered Hippocampal and Striatal Expression of Endothelial Markers and VIP/PACAP Neuropeptides in a Mouse Model of Systemic Lupus Erythematosus.
Lee J; Thomas Broome S; Jansen MI; Mandwie M; Logan GJ; Marzagalli R; Musumeci G; Castorina A
Journal article: CURRENT ISSUES IN MOLECULAR BIOLOGY. 2022;44(10):4500-4516
Pro-Inflammatory and Pro-Apoptotic Effects of the Non-Protein Amino Acid L-Azetidine-2-Carboxylic Acid in BV2 Microglial Cells.
Piper JA; Jansen MI; Thomas Broome S; Rodgers KJ; Musumeci G; Castorina A
Journal article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(9):4788
Exploring the Pro-Phagocytic and Anti-Inflammatory Functions of PACAP and VIP in Microglia: Implications for Multiple Sclerosis.
Jansen MI; Thomas Broome S; Castorina A
Journal article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(3):1845
The Anxiolytic Drug Buspirone Prevents Rotenone-Induced Toxicity in a Mouse Model of Parkinson's Disease.
Thomas Broome S; Castorina A
Journal article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(20):10947
PACAP and VIP Modulate LPS-Induced Microglial Activation and Trigger Distinct Phenotypic Changes in Murine BV2 Microglial Cells.
Karunia J; Niaz A; Mandwie M; Thomas Broome S; Keay KA; Waschek JA; Al-Badri G; Castorina A
Journal article: APPLIED SCIENCES-BASEL. 2021;11(16):7673
Doxycycline and Minocycline Act as Positive Allosteric Modulators of the PAC1 Receptor and Induce Plasminogen Activators in RT4 Schwann Cells
Broome ST; Musumeci G; Castorina A
Journal article: CELLS. 2021;10(6):1312
Assessing the Anti-Inflammatory Activity of the Anxiolytic Drug Buspirone Using CRISPR-Cas9 Gene Editing in LPS-Stimulated BV-2 Microglial Cells.
Thomas Broome S; Fisher T; Faiz A; Keay KA; Musumeci G; Al-Badri G; Castorina A
Journal article: NEURAL REGENERATION RESEARCH. 2020;15(12):2173
Dopamine: an immune transmitter.
Thomas Broome S; Louangaphay K; Keay KA; Leggio GM; Musumeci G; Castorina A

All other publications

Preprint: BIORXIV. 2024
Hippocampal neuroinflammation causes sex-specific disruptions in action selection, food approach memories, and neuronal activation
Ganesan K; Ghorbanpour S; Kendall W; Broome ST; Gladding J; Dhungana A; Abiero AR; Mahmoudi M; Castorina A; Kendig M; Becchi S; Valova V; Cole L; Bradfield L
Preprint: PREPRINTS.ORG. 2021
PACAP and VIP Modulate LPS-induced Microglial Activation and Trigger Distinct Phenotypic Changes in Murine BV2 Microglial Cells
Karunia J; Niaz A; Mandwie M; Thomas Broome S; Keay K; Waschek J; Al-Badri G; Castorina A
Preprint: PREPRINTS.ORG. 2021
Doxycycline and Minocycline act as Positive Allosteric Modulators of the PAC1 Receptor and Induce Plasminogen Activators in RT4 Schwann Cells
Thomas Broome S; Musumeci G; Castorina A

Grants

Postdoctoral Fellow
Foundation pour la Recherche Medicale
1 January 2024 - 30 April 2025
Fulbright Postdoctoral Scholar
Fulbright Association
3 October 2022 - 8 August 2023
BRI Knaub Fellowship in Multiple Sclerosis
University of California, Los Angeles
3 October 2022 - 3 August 2023

Employments

Postdoctoral Researcher, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2025-2027

Other expert reviewer/evaluation assignment

Evaluator of research applications in international competition, Application manager and reviewer for GWiS Fellowships, Graduate Women in Science, 2025

Articles

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Grants

Employments

Other expert reviewer/evaluation assignment

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