Sara Gredmark Russ

Sara Gredmark Russ

Adjunct Senior Lecturer | Docent
Visiting address: Alfred Nobels allé 8, plan 7, 14152 Huddinge
Postal address: H7 Medicin, Huddinge, H7 CIM Gredmark Russ, 171 77 Stockholm
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About me

  • The research in our group lies within the area of immunology, with the main focus on viruses and their interactions with the immune system.

Research

  • Viral infections can cause a number of different acute and chronic conditions. The approaches to treat these conditions are limited, and for many viral infections, there are no alternatives at all. Our research focuses on advancing the knowledge in the basic principles of the immune response to viral infections in humans. Our long-term goal is, aside from gaining knowledge in the basic functions of the human immune system, to contribute to the development of new diagnostics, treatment, and vaccination strategies for viral infections.
    Studies of TBEV virus

    One of the main subjects of our research is tick-borne encephalitis virus (TBEV). TBEV is a member of the flavivirus family, and is transferred to humans from ticks. TBEV is the causative agent of tick-borne encephalitis (TBE). One major problems with TBE is the risk for long lasting neurological sequelae. TBE is an emerging disease and has become a growing health challenge in endemic areas. The only effective protection against TBE is properly timed vaccination, before the exposure to TBEV-infected ticks.
    The TBE disease progression in humans. Illustration: Servier Medical Art

    Despite the fact that vaccination against TBE is increasing in the at-risk population in Sweden, the numbers of patients suffering from TBE have also been increasing over the last decade. In addition, over the last years a number of vaccine failures have been reported.

    Even though TBE has become an important public health concern, the underlying basis for the development of encephalitis in TBEV infection remains undefined, and there are only a few studies addressing the mechanism of disease development.

Articles

All other publications

Employments

  • Adjunct Senior Lecturer, Department of Medicine, Huddinge, Karolinska Institutet, 2021-2025

Degrees and Education

  • Docent, Karolinska Institutet, 2019
  • Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2005
  • University Medical Degree, Karolinska Institutet, 2001

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