Sander Lambo

Sander Lambo

Assistant Professor
Telephone: +46852482391
Visiting address: BioClincium, Visionsgatan 4, våning 6, 17164 Solna
Postal address: K7 Onkologi-Patologi, K7 Forskning Schlisio Lambo, 171 77 Stockholm
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About me

  • Sander Lambo is an assistant professor at the department of Oncology-Pathology since August 2026. His main research focus is to identify the epigenetic mechanisms that occur in pediatric cancers during initiation of the tumor and resistance to therapy. 

    He has obtained his PhD at the German Cancer Research Centre (DKFZ) between 2014 and 2019 at the laboratory of Stefan Pfister where he studied the genomics and epigenetics of pediatric brain tumors and he characterized a newly identified brain tumor entity named Embryonal Tumor with Multilayered Rosettes. During his postdoctoral studies he investigated the transcriptional and epigenetic cellular plasticity observed across pediatric Acute Myeloid Leukemia after exposure to therapy at Canada's Michael Smith Genome Sciences Centre in the laboratory of Marco Marra (2020-2023) and co-developed a new methodology for generating scalable single cell methylation named Droplet-based Restriction Enzyme and Methylation  sequencing (DREAM-seq) at the Dana-Farber Cancer Institute in the lab of Volker Hovestadt together with the lab of Bradley Bernstein (2023-2026).

Research

  • He and his team are interested in identifying the epigenetic patterns that underlie the initiation and progression of pediatric tumors. Using novel sequencing approaches including high-throughput single cell DNA methylation sequencing they investigate the epigenetic heterogeneity and cellular plasticity in pediatric tumors in order to learn more about how pediatric tumors evolve and adapt. For more information please refer to the research team website.

Articles

  • Article: BLOOD. 2025;146(25):3019-3035
    Fleming TJ; Antoszewski M; Lambo S; Gundry MC; Piussi R; Wahlster L; Shah S; Reed FE; Dong KD; Paulo JA; Gygi SP; Mimoso C; Goldman SR; Adelman K; Perry JA; Pikman Y; Stegmaier K; Barrachina MN; Machlus KR; Hovestadt V; Arruda A; Minden MD; Voit RA; Sankaran VG
  • Article: NATURE CANCER. 2025;6(6):1035-1055
    Beck A; Gabler-Pamer L; Alencastro Veiga Cruzeiro G; Lambo S; Englinger B; Shaw ML; Hack OA; Liu I; Haase RD; de Biagi CAO; Baumgartner A; Nascimento Silva AD; Klenner M; Freidel PS; Herms J; von Baumgarten L; Tonn JC; Thon N; Bruckner K; Madlener S; Mayr L; Senfter D; Peyrl A; Slavc I; Lötsch D; Dorfer C; Geyregger R; Amberg N; Haberler C; Mack N; Schwalm B; Pfister SM; Korshunov A; Baird LC; Yang E; Chi SN; Alexandrescu S; Gojo J; Kool M; Hovestadt V; Filbin MG
  • Article: CANCER CELL. 2023;41(12):2117-2135.e12
    Lambo S; Trinh DL; Ries RE; Jin D; Setiadi A; Ng M; Leblanc VG; Loken MR; Brodersen LE; Dai F; Pardo LM; Ma X; Vercauteren SM; Meshinchi S; Marra MA
  • Article: GENOME MEDICINE. 2023;15(1):67
    Nabbi A; Beck P; Delaidelli A; Oldridge DA; Sudhaman S; Zhu K; Yang SYC; Mulder DT; Bruce JP; Paulson JN; Raman P; Zhu Y; Resnick AC; Sorensen PH; Sill M; Brabetz S; Lambo S; Malkin D; Johann PD; Kool M; Jones DTW; Pfister SM; Jäger N; Pugh TJ
  • Article: FRONTIERS IN ONCOLOGY. 2020;10:584681
    Mayr L; Gojo J; Peyrl A; Azizi AA; Stepien NM; Pletschko T; Czech T; Dorfer C; Lambo S; Dieckmann K; Haberler C; Kool M; Slavc I
  • Article: NATURE. 2019;576(7786):274-280
    Lambo S; Gröbner SN; Rausch T; Waszak SM; Schmidt C; Gorthi A; Romero JC; Mauermann M; Brabetz S; Krausert S; Buchhalter I; Koster J; Zwijnenburg DA; Sill M; Hübner J-M; Mack N; Schwalm B; Ryzhova M; Hovestadt V; Papillon-Cavanagh S; Chan JA; Landgraf P; Ho B; Milde T; Witt O; Ecker J; Sahm F; Sumerauer D; Ellison DW; Orr BA; Darabi A; Haberler C; Figarella-Branger D; Wesseling P; Schittenhelm J; Remke M; Taylor MD; Gil-da-Costa MJ; Łastowska M; Grajkowska W; Hasselblatt M; Hauser P; Pietsch T; Uro-Coste E; Bourdeaut F; Masliah-Planchon J; Rigau V; Alexandrescu S; Wolf S; Li X-N; Schüller U; Snuderl M; Karajannis MA; Giangaspero F; Jabado N; von Deimling A; Jones DTW; Korbel JO; von Hoff K; Lichter P; Huang A; Bishop AJR; Pfister SM; Korshunov A; Kool M
  • Article: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. 2019;45(2):108-118
    Korshunov A; Casalini B; Chavez L; Hielscher T; Sill M; Ryzhova M; Sharma T; Schrimpf D; Stichel D; Capper D; Reuss DE; Sturm D; Absalyamova O; Golanov A; Lambo S; Bewerunge-Hudler M; Lichter P; Herold-Mende C; Wick W; Pfister SM; Kool M; Jones DTW; von Deimling A; Sahm F
  • Article: NATURE. 2018;555(7696):321-327
    Gröbner SN; Worst BC; Weischenfeldt J; Buchhalter I; Kleinheinz K; Rudneva VA; Johann PD; Balasubramanian GP; Segura-Wang M; Brabetz S; Bender S; Hutter B; Sturm D; Pfaff E; Hübschmann D; Zipprich G; Heinold M; Eils J; Lawerenz C; Erkek S; Lambo S; Waszak S; Blattmann C; Borkhardt A; Kuhlen M; Eggert A; Fulda S; Gessler M; Wegert J; Kappler R; Baumhoer D; Burdach S; Kirschner-Schwabe R; Kontny U; Kulozik AE; Lohmann D; Hettmer S; Eckert C; Bielack S; Nathrath M; Niemeyer C; Richter GH; Schulte J; Siebert R; Westermann F; Molenaar JJ; Vassal G; Witt H; ICGC PedBrain-Seq Project; ICGC MMML-Seq Project; Burkhardt B; Kratz CP; Witt O; van Tilburg CM; Kramm CM; Fleischhack G; Dirksen U; Rutkowski S; Frühwald M; von Hoff K; Wolf S; Klingebiel T; Koscielniak E; Landgraf P; Koster J; Resnick AC; Zhang J; Liu Y; Zhou X; Waanders AJ; Zwijnenburg DA; Raman P; Brors B; Weber UD; Northcott PA; Pajtler KW; Kool M; Piro RM; Korbel JO; Schlesner M; Eils R; Jones DTW; Lichter P; Chavez L; Zapatka M; Pfister SM
  • Article: NATURE MEDICINE. 2017;23(10):1191-1202
    Neumann JE; Wefers AK; Lambo S; Bianchi E; Bockstaller M; Dorostkar MM; Meister V; Schindler P; Korshunov A; von Hoff K; Nowak J; Warmuth-Metz M; Schneider MR; Renner-Müller I; Merk DJ; Shakarami M; Sharma T; Chavez L; Glass R; Chan JA; Taketo MM; Neumann P; Kool M; Schüller U
  • Article: NATURE COMMUNICATIONS. 2017;8:14758
    Feng W; Kawauchi D; Körkel-Qu H; Deng H; Serger E; Sieber L; Lieberman JA; Jimeno-González S; Lambo S; Hanna BS; Harim Y; Jansen M; Neuerburg A; Friesen O; Zuckermann M; Rajendran V; Gronych J; Ayrault O; Korshunov A; Jones DTW; Kool M; Northcott PA; Lichter P; Cortés-Ledesma F; Pfister SM; Liu H-K
  • Article: GENES CHROMOSOMES & CANCER. 2016;55(5):418-427
    Sahm F; Jakobiec FA; Meyer J; Schrimpf D; Eberhart CG; Hovestadt V; Capper D; Lambo S; Ryzhova M; Schüller U; Zheludkova O; Kumirova E; Lichter P; von Deimling A; Jones DTW; Pfister SM; Kool M; Korshunov A

All other publications

  • Letter: HEMASPHERE. 2025;9(9):e70212
    Koedijk JB; Barneh F; Meesters-Ensing JI; van Tuil M; Sonneveld E; Lambo S; Perzolli A; Schweighart EK; Ferrao Blanco MN; van der Meulen M; Deli A; Haasjes E; Bang Christensen K; de Groot-Kruseman HA; Meshinchi S; Hasle H; Belderbos ME; Luesink M; Goemans BF; Nierkens S; Hehir-Kwa J; Zwaan CM; Heidenreich O
  • Preprint: BIORXIV. 2025;BIORXIV
    Schneider C; Alexe G; Merickel LA; Meyer A; Swift ML; Serafim RB; Basanthakumar AT; Taillon A; Salhotra S; Boniolo F; Lambo S; Rodriguez Y; Häupl B; George RE; Root DE; Oellerich T; Hovestadt V; Chowdhury D; Stegmaier K
  • Preprint: BIORXIV. 2025
    Koedijk JB; Barneh F; Meesters-Ensing JE; van Tuil M; Sonneveld E; Lambo S; Perzolli A; Schweighart EK; Blanco MNF; van der Meulen M; Deli A; Haasjes E; Christensen KB; de Groot-Kruseman HA; Meshinchi S; Hasle H; Belderbos ME; Luesink M; Goemans BF; Nierkens S; Hehir-Kwa J; Zwaan CM; Heidenreich O
  • Preprint: BIORXIV. 2024;BIORXIV
    Fleming TJ; Antoszewski M; Lambo S; Gundry MC; Piussi R; Wahlster L; Shah S; Reed FE; Dong KD; Paulo JA; Gygi SP; Mimoso C; Goldman SR; Adelman K; Perry JA; Pikman Y; Stegmaier K; Barrachina MN; Machlus KR; Hovestadt V; Arruda A; Minden MD; Voit RA; Sankaran VG
  • Review: ACTA NEUROPATHOLOGICA. 2020;140(3):249-266
    Lambo S; von Hoff K; Korshunov A; Pfister SM; Kool M
  • Letter: ACTA NEUROPATHOLOGICA. 2019;137(1):175-177
    Uro-Coste E; Masliah-Planchon J; Siegfried A; Blanluet M; Lambo S; Kool M; Roujeau T; Boetto S; Palenzuela G; Bertozzi A-I; Gambart M; Coupier I; Oliver-Petit I; Golmard L; Julia S; Savagner F; Mohand-Oumoussa B; Tauziede-Espariat A; Delisle M-B; Figarella-Branger D; Bourdeaut F; Rigau V
  • Corrigendum: NATURE. 2018;559(7714):E10
    Gröbner SN; Worst BC; Weischenfeldt J; Buchhalter I; Kleinheinz K; Rudneva VA; Johann PD; Balasubramanian GP; Segura-Wang M; Brabetz S; Bender S; Hutter B; Sturm D; Pfaff E; Hübschmann D; Zipprich G; Heinold M; Eils J; Lawerenz C; Erkek S; Lambo S; Waszak S; Blattmann C; Borkhardt A; Kuhlen M; Eggert A; Fulda S; Gessler M; Wegert J; Kappler R; Baumhoer D; Burdach S; Kirschner-Schwabe R; Kontny U; Kulozik AE; Lohmann D; Hettmer S; Eckert C; Bielack S; Nathrath M; Niemeyer C; Richter GH; Schulte J; Siebert R; Westermann F; Molenaar JJ; Vassal G; Witt H; Burkhardt B; Kratz CP; Witt O; van Tilburg CM; Kramm CM; Fleischhack G; Dirksen U; Rutkowski S; Frühwald M; von Hoff K; Wolf S; Klingebiel T; Koscielniak E; Landgraf P; Koster J; Resnick AC; Zhang J; Liu Y; Zhou X; Waanders AJ; Zwijnenburg DA; Raman P; Brors B; Weber UD; Northcott PA; Pajtler KW; Kool M; Piro RM; Korbel JO; Schlesner M; Eils R; Jones DTW; Lichter P; Chavez L; Zapatka M; Pfister SM; ICGC PedBrain-Seq Project; ICGC MMML-Seq Project

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