Samir El Andaloussi
Professor | Docent
E-mail: samir.el-andaloussi@ki.se
Telephone: +46852483571
Mobile phone: +46737121613
Visiting address: Hälsovägen 7, Novum plan 5, 14157
Postal address: H5 Laboratoriemedicin, H5 BCM El Andaloussi, 141 52 Huddinge
About me
- Leader of exosome research. Professor of Biomolecular Medicine and Advanced Therapy at Karolinska Institutet since 1 November 2021.
Research
- Research area/interest: Characterization and application of biological nanovesicles, exosomes, for drug delivery and development of novel oligonucleotide-based drugs to interfere with gene expression.
Articles
- Article: NATURE BIOTECHNOLOGY. 2024;42(4):587-590
- Article: NATURE MICROBIOLOGY. 2024;9(4):905-921
- Article: STEM CELL RESEARCH AND THERAPY. 2024;15(1):77
- Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2024;129:111584
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2024;13(1):e12396
- Article: MOLECULAR THERAPY: NUCLEIC ACIDS. 2023;33:511-528
- Article: SCIENCE ADVANCES. 2023;9(35):eadh1168
- Article: HAEMATOLOGICA. 2023;108(9):2422-2434
- Article: SCIENTIFIC REPORTS. 2023;13(1):13589
- Article: NATURE COMMUNICATIONS. 2023;14(1):4734
- Article: CELL DEATH DISCOVERY. 2023;9(1):260
- Article: JOURNAL OF CONTROLLED RELEASE. 2023;357:630-640
- Article: LEUKEMIA. 2023;37(4):888-900
- Article: NANOSCALE ADVANCES. 2023;5(6):1691-1705
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2023;12(2):e12306
- Journal article: EXTRACELLULAR VESICLES AND CIRCULATING NUCLEIC ACIDS. 2023;4(2):170-190
- Article: SCIENCE IMMUNOLOGY. 2022;7(78):eadd3330
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(12):e12290
- Article: BIOMATERIALS. 2022;290:121830
- Article: CANCER GENE THERAPY. 2022;29(11):1600-1615
- Article: JOURNAL OF ALZHEIMER'S DISEASE. 2022;90(1):333-348
- Article: MOLECULAR THERAPY. 2022;30(9):3078-3094
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(7):e12248
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(6):e12238
- Article: NANOSCALE. 2022;14(12):4690-4704
- Article: ADVANCED HEALTHCARE MATERIALS. 2022;11(5):e2101658
- Article: COMMUNICATIONS BIOLOGY. 2022;5(1):185
- Article: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 2022;170:59-69
- Article: PHARMACEUTICS. 2021;14(1):38
- Article: NATURE COMMUNICATIONS. 2021;12(1):6666
- Article: BIOMOLECULES. 2021;11(11):1606
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2021;10(12):e12142
- Article: NATURE BIOMEDICAL ENGINEERING. 2021;5(9):1084-1098
- Article: ECLINICALMEDICINE. 2021;38:100988
- Article: CELLS. 2021;10(6):1543
- Article: PHARMACEUTICS. 2021;13(6):878
- Article: ACS APPLIED POLYMER MATERIALS. 2021;3(4):2197-2210
- Article: PHARMACEUTICS. 2021;13(1):116
- Article: FRONTIERS IN PHYSIOLOGY. 2021;12:689179
- Article: BIOMATERIALS. 2021;266:120435
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2020;48(21):12234-12251
- Article: MOLECULAR MEDICINE REPORTS. 2020;22(6):4589-4600
- Article: MOLECULAR & CELLULAR PROTEOMICS. 2020;19(12):2047-2068
- Article: CELLS. 2020;9(9):E2123-2123
- Article: MOLECULAR THERAPY: METHODS & CLINICAL DEVELOPMENT. 2020;18:880-892
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2020;9(1):1808281
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2020;9(1):1800222
- Article: CYTOMETRY. PART A : THE JOURNAL OF THE INTERNATIONAL SOCIETY FOR ANALYTICAL CYTOLOGY. 2020;97(6):602-609
- Article: NATURE COMMUNICATIONS. 2020;11(1):1113
- Article: METHODS IN MOLECULAR BIOLOGY. 2020;2109:35-44
- Article: FRONTIERS IN NEUROSCIENCE. 2020;14:256
- Article: FRONTIERS IN AGING NEUROSCIENCE. 2020;12:553635
- Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2020;78:106042
- Article: PHARMACEUTICS. 2019;11(12):E666-666
- Article: ADVANCED FUNCTIONAL MATERIALS. 2019;29(48)
- Article: NATURE COMMUNICATIONS. 2019;10(1):2331
- Article: ACS SENSORS. 2019;4(5):1399-1408
- Article: DIABETES. 2019;68(3):515-526
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2019;8(1):1663043
- Article: FRONTIERS IN NEUROSCIENCE. 2019;13:1067
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2019;8(1):1587567
- Article: METHODS IN MOLECULAR BIOLOGY. 2019;1953:287-299
- Article: MOLECULAR THERAPY: NUCLEIC ACIDS. 2018;13:1-15
- Article: PROTEOMICS. 2018;18(24):e1800257
- Article: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 2018;132:29-40
- Article: SCIENTIFIC REPORTS. 2018;8(1):15841
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2018;504(4):749-752
- Article: SCIENTIFIC REPORTS. 2018;8(1):10813
- Article: FRONTIERS IN IMMUNOLOGY. 2018;9:1326
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2018;7(1):1535750
- Journal article: NEUROMUSCULAR DISORDERS. 2017;27:S167-S168
- Article: SCIENTIFIC REPORTS. 2017;7(1):11561
- Article: BRAIN. 2017;140(4):887-897
- Article: METHODS IN MOLECULAR BIOLOGY. 2017;1545:197-204
- Journal article: CHINESE NEUROSURGICAL JOURNAL. 2016;2(1):36
- Article: NUCLEIC ACID THERAPEUTICS. 2016;26(6):381-391
- Article: HUMAN MOLECULAR GENETICS. 2016;25(18):3960-3974
- Article: DIABETOLOGIA. 2016;59(5):1049-1058
- Article: JOURNAL OF CELL BIOLOGY. 2016;213(2):173-184
- Article: MOLECULAR THERAPY: NUCLEIC ACIDS. 2016;5(3):e290
- Article: SCIENTIFIC REPORTS. 2016;6:22519
- Article: GENOMICS DATA. 2016;7:88-89
- Article: STEM CELLS. 2016;34(3):601-613
- Article: HUMAN MOLECULAR GENETICS. 2015;24(23):6756-6768
- Article: STEM CELLS TRANSLATIONAL MEDICINE. 2015;4(10):1199-1213
- Journal article: ZENTRALBLATT FUR CHIRURGIE. 2015;140(S 01)
- Article: HUMAN MOLECULAR GENETICS. 2015;24(15):4225-4237
- Article: NANO LETTERS. 2015;15(7):4364-4373
- Article: NANOMEDICINE: NANOTECHNOLOGY, BIOLOGY, AND MEDICINE. 2015;11(4):879-883
- Article: NUCLEIC ACID THERAPEUTICS. 2015;25(2):65-77
- Article: NATURE MEDICINE. 2015;21(3):270-275
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2015;4:30087
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2015;4:26883
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2015;4:26316
- Article: PLOS ONE. 2015;10(12):e0145686
- Journal article: RESPIRATION. 2015;90(6):481-492
- Article: MOLECULAR THERAPY: NUCLEIC ACIDS. 2014;3(11):e212
- Article: MOVEMENT DISORDERS. 2014;29(12):1476-1485
- Article: DIABETOLOGIA. 2014;57(10):2155-2164
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2014;124(9):4067-4081
- Article: MOLECULAR CANCER THERAPEUTICS. 2014;13(4):996-1007
- Article: NUCLEIC ACID THERAPEUTICS. 2014;24(1):13-24
- Article: MOLECULAR THERAPY: NUCLEIC ACIDS. 2014;3(1):e140
- Article: NATURE REVIEWS DRUG DISCOVERY. 2013;12(5):347-357
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2013;41(5):3257-3273
- Article: NATURE PROTOCOLS. 2012;7(12):2112-2126
- Article: HUMAN MOLECULAR GENETICS. 2012;21(R1):R125-R134
- Article: BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS. 2012;22(17):5635-5638
- Article: JOURNAL OF CONTROLLED RELEASE. 2012;162(1):1-8
- Article: MOLECULAR THERAPY: NUCLEIC ACIDS. 2012;1(8):e39
- Article: MOLECULAR THERAPY: NUCLEIC ACIDS. 2012;1(5):e23
- Article: THE FASEB JOURNAL. 2012;26(3):1172-1180
- Article: ISRN PHARMACEUTICS. 2012;2012:407154-7
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2012;40(1):438-448
- Article: MOLECULAR THERAPY. 2011;19(8):1457-1467
- Article: JOURNAL OF CONTROLLED RELEASE. 2011;153(2):163-172
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2011;39(12):5284-5298
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2011;1808(6):1544-1551
- Article: VIROLOGY JOURNAL. 2011;8:243
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2011;39(9):3972-3987
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2011;39(3):1142-1154
- Article: METHODS IN MOLECULAR BIOLOGY. 2011;764:75-89
- Article: METHODS IN MOLECULAR BIOLOGY. 2011;683:361-373
- Article: METHODS IN MOLECULAR BIOLOGY. 2011;683:219-230
- Article: METHODS IN MOLECULAR BIOLOGY. 2011;683:195-205
- Article: EXPERT OPINION ON THERAPEUTIC PATENTS. 2011;21(1):115-119
- Article: BIOCONJUGATE CHEMISTRY. 2010;21(9):1662-1672
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2010;1798(3):338-343
- Article: JOURNAL OF CONTROLLED RELEASE. 2010;141(1):42-51
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1788(12):2509-2517
- Article: JOURNAL OF CONTROLLED RELEASE. 2009;134(3):221-227
- Article: INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS. 2009;15(1):11-15
- Article: BIOCONJUGATE CHEMISTRY. 2008;19(12):2535-2542
- Journal article: AIP CONFERENCE PROCEEDINGS. 2008;1062(1):73-88
- Article: BIOCHEMICAL JOURNAL. 2008;412(2):307-313
- Article: INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS. 2008;14(1):58-63
- Article: MOLECULAR THERAPY. 2008;16(1):115-123
- Article: MOLECULAR THERAPY. 2008;16(1):115-123
- Article: BIOCHEMICAL JOURNAL. 2007;407(2):285-292
- Article: MOLECULAR THERAPY. 2007;15(10):1820-1826
- Article: THE FASEB JOURNAL. 2007;21(11):2664-2671
- Article: BIOCHEMICAL SOCIETY TRANSACTIONS. 2007;35(Pt 4):770-774
- Article: NATURE PROTOCOLS. 2007;2(8):2043-2047
- Article: JOURNAL OF GENE MEDICINE. 2006;8(10):1262-1273
- Article: JOURNAL OF CONTROLLED RELEASE. 2005;110(1):189-201
- Article: JOURNAL OF CONTROLLED RELEASE. 2005;103(2):511-523
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All other publications
- Preprint: RESEARCH SQUARE. 2023
- Review: MOLECULAR THERAPY. 2023;31(5):1231-1250
- Review: HANDBOOK OF CLINICAL NEUROLOGY. 2023;193:227-241
- Conference publication: MOLECULAR THERAPY. 2023;31(4):730
- Conference publication: MOLECULAR THERAPY. 2023;31(4):627
- Review: HANDBOOK OF CLINICAL NEUROLOGY. 2023;193:243-266
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2023;70:S27
- Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S64
- Other: RESPIRATION. 2023;102(5):402-404
- Conference publication: BLOOD. 2022;140:4463-4464
- Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(12):S266
- Conference publication: CYTOTHERAPY. 2022;24(5):S94-S95
- Conference publication: TISSUE ENGINEERING - PART A.. 2022;28:S250
- Corrigendum: NATURE COMMUNICATIONS. 2021;12(1):7357
- Corrigendum: ACS NANO. 2021;15(11):18590-18591
- Review: ADVANCED DRUG DELIVERY REVIEWS. 2021;178:113961
- Review: ACS NANO. 2021;15(9):13993-14021
- Review: NATURE METHODS. 2021;18(9):1013-1026
- Conference publication: MOLECULAR THERAPY. 2021;29(4):220
- Corrigendum: NATURE COMMUNICATIONS. 2020;11(1):1701
- Corrigendum: METHODS IN MOLECULAR BIOLOGY. 2020;2109:293
- Editorial comment: NATURE BIOMEDICAL ENGINEERING. 2020;4(1):9-11
- Review: ADVANCED DRUG DELIVERY REVIEWS. 2020;159:332-343
- Review: SCIENCE TRANSLATIONAL MEDICINE. 2019;11(492):eaav8521
- Corrigendum: BRAIN. 2018;141(5):e42
- Published conference paper: MOLECULAR THERAPY. 2017;25(7):1580-1587
- Review: CIRCULATION RESEARCH. 2017;120(10):1632-1648
- Review: EMBO MOLECULAR MEDICINE. 2017;9(5):545-557
- Conference publication: CELL TRANSPLANTATION. 2017;26(4):704
- Conference publication: CELL TRANSPLANTATION. 2017;26:704
- Conference publication: MOLECULAR THERAPY. 2017;25(5):121-122
- Conference publication: MOLECULAR THERAPY. 2017;25(5):36
- Conference publication: NEUROMUSCULAR DISORDERS. 2017;27:S31-S32
- Conference publication: NEUROMUSCULAR DISORDERS. 2017;27:S5-S6
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):290
- Review: ADVANCED DRUG DELIVERY REVIEWS. 2016;106(Pt A):172-182
- Review: NATURE REVIEWS NEUROLOGY. 2016;12(6):346-357
- Corrigendum: STEM CELLS TRANSLATIONAL MEDICINE. 2016;5(6):845
- Editorial comment: ACS NANO. 2016;10(4):3886-3899
- Review: METHODS IN MOLECULAR BIOLOGY. 2016;1364:291-310
- Conference publication: CELL TRANSPLANTATION. 2016;25(4):750
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46:1084
- Conference publication: NEUROMUSCULAR DISORDERS. 2015;25:S312-S313
- Review: HUMAN GENE THERAPY. 2015;26(8):506-517
- Review: CURRENT ALLERGY AND ASTHMA REPORTS. 2015;15(3):510
- Editorial comment: MOLECULAR THERAPY. 2014;22(3):485-486
- Conference publication: JOURNAL OF CLINICAL IMMUNOLOGY. 2014;34:S152
- Review: ADVANCED DRUG DELIVERY REVIEWS. 2013;65(3):391-397
- Review: MOLECULAR THERAPY: NUCLEIC ACIDS. 2012;1(6):e27
- Review: CURRENT GENE THERAPY. 2012;12(3):161-178
- Editorial comment: MOLECULAR THERAPY: NUCLEIC ACIDS. 2012;1(5):e24
- Conference publication: JOURNAL OF CLINICAL IMMUNOLOGY. 2012;32:165-166
- Review: METHODS IN MOLECULAR BIOLOGY. 2011;683:233-247
- Review: METHODS IN MOLECULAR BIOLOGY. 2011;683:207-217
- Review: EXPERT OPINION ON DRUG DELIVERY. 2010;7(6):721-735
- Review: CURRENT PHARMACEUTICAL DESIGN. 2010;16(9):1167-1178
- Review: EXPERT OPINION ON DRUG DELIVERY. 2009;6(11):1195-1205
- Book chapter: HANDBOOK OF CELL-PENETRATING PEPTIDES, SECOND EDITION: PHARMACOLOGY AND TOXICOLOGY: BASIC AND CLINICAL ASPECTS. 2006;p. 375-386
- Review: CURRENT PHARMACEUTICAL DESIGN. 2005;11(28):3597-3611
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Grants
- Ming Wai Lau Centre for Reparative Medicine (MWLC)1 January 2024 - 31 December 2026
- VINNOVA29 September 2023 - 30 June 2024
- Platform development of innovative bioconjugates for cardiac delivery of antisense oligonucleotidesNovo Nordisk Foundation (NNF)1 August 2023 - 1 August 2026
- Knut och Alice Wallenberg Stiftelse (KAW)1 July 2023 - 31 December 2028
- TransNAT: Transforming delivery, safety and efficacy of nucleic acid therapeutics: from intracellular uptake to targeting brain and muscleMedical Research Council1 November 2022 - 31 October 2025
- UK Research and Innovation1 November 2022 - 31 October 2025
- Cancerfonden1 January 2022 - 31 December 2024
- European Research Council1 March 2021 - 28 February 2026
- EU-projekt DELIVER, Grant Agreement number 101001374European Research Council (ERC)1 March 2021 - 28 February 2026
- Swedish Research Council1 January 2021 - 31 December 2024
- Development of modified extracellular vesicles for targeted delivery of RNA therapySwedish Research Council1 January 2021 - 31 December 2025
- US Army1 September 2020 - 31 March 2024
- Muscle-Targeted Cell-Penetrating Peptides for Delivery of Cas9-RNPs and Modified mRNA to Dystrophic MuscleCongressionally Directed Medical Research Programs1 September 2020 - 31 August 2023
- European Commission1 September 2019 - 28 February 2025
- Swedish Foundation for Strategic Research (SSF)12 September 2017 - 31 December 2024
- Swedish Research Council1 January 2016 - 31 December 2019
- Biotechnology and Biological Sciences Research Council30 September 2015 - 31 March 2019
- Medical Research Council31 August 2015 - 29 April 2021
- Financing of Swedish sub-project within the project GlioEx. Call 2013 in the ERA-Net EuroNanoMed II.Swedish Research Council1 January 2014 - 31 December 2016
Employments
- Professor, Department of Laboratory Medicine, Karolinska Institutet, 2021-
Degrees and Education
- Docent, Karolinska Institutet, 2018
- Phd, Stockholm University, 2008
- Examen i molekylär cellbiologi, Södertörn University, 2002
Visiting research fellowships
- Research fellow at University of Oxford, 2013-2018
- Postdocs at University of Oxford, 2011-2013
- Postdocs, 2010-2012
- Postdocs vid Stockholms universitet 2008–2010, 2008-2010