Ruyue Zhang

About me
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Grants
CV
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About me

I'm a postdoc in psychiatric genetics and epidemiology at MEB, and a visiting researcher in the Department of Genetics, UNC Chapel Hill

Teaching

2024, “Topics in Statistical Genetics and Genomics”, UNC Chapel Hill
2023, “Applied Epidemiology II - Genetic epidemiology”, Karolinska Institutet
2018, “Biostatistics I- Introduction for Epidemiologists”, Karolinska Institutet

Articles

Journal article: TRANSLATIONAL PSYCHIATRY. 2025;15(1):215
Elevated plasma GDF15 combined with FGF21 suggests mitochondrial dysfunction in a subgroup of anorexia nervosa patients
Xu J; Zhang R; Millischer V; Stiernborg M; Tume CE; Mehdinia S; Barker P; Yilmaz Z; Goncalves VF; Lavebratt C; Landen M; O'Rahilly S; Bulik CM; Nilsson IAK
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2024;87:173
FEWER TELLS MORE: A POLYGENIC RISK SCORE VARIANT PRIORITIZATION PIPELINE FOR DEPRESSION ACROSS ANCESTRIES
Zhang R; Kharitonova E; Sun Q; Wen J; Raffield L; Haessler J; Kooperberg C; Sullivan P; Li Y
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2024;87:217-218
SHARED ETIOLOGICAL FACTORS BETWEEN AVOIDANT RESTRICTIVE FOOD INTAKE DISORDER (ARFID) AND CO-OCCURRING NEURODEVELOPMENTAL AND PSYCHIATRIC CONDITIONS: EVIDENCE FROM TWIN AND POLYGENIC SCORE ANALYSES
Dinkler L; Zhang R; Hog L; Lichtenstein P; Lundstrom S; Larsson H; Bulik C; Taylor M; Kuja-Halkola R
Article: BRITISH JOURNAL OF NUTRITION. 2024;132(5):631-639
Disordered eating and cardiometabolic risk factors in Chinese women: evidence from the China Health and Nutrition Survey
Qi B; Cooper GE; Thornton LM; Zhang R; Yao S; Howard AG; Gordon-Larsen P; Du S; Wang H; Zhang B; Bulik CM; North KE; Munn-Chernoff MA
Article: TRANSLATIONAL PSYCHIATRY. 2023;13(1):366
The impact of genetic risk for schizophrenia on eating disorder clinical presentations
Zhang R; Kuja-Halkola R; Borg S; Leppae V; Thornton LM; Birgegard A; Bulik CM; Bergen SE
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2023;75:s232-s233
EVALUATION OF THE ASSOCIATION BETWEEN SUICIDALITY AND POLYGENIC RISK SCORES FOR ANOREXIA NERVOSA, SUICIDE ATTEMPTS, AND SUICIDAL IDEATION
Zhang R; Termorshuizen J; Birgegard A; Thornton L; Sullivan P; Bulik C; Abbaspour A
Article: PSYCHOLOGICAL MEDICINE. 2023;53(2):371-378
Association of family history of schizophrenia and clinical outcomes in individuals with eating disorders
Zhang R; Kuja-Halkola R; Birgegard A; Larsson H; Lichtenstein P; Bulik CM; Bergen SE
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2022;179(11):824-832
Genetic and Environmental Contribution to the Co-Occurrence of Endocrine-Metabolic Disorders and Depression: A Nationwide Swedish Study of Siblings
Leone M; Kuja-Halkola R; Leval A; Butwicka A; Skov J; Zhang R; Liu S; Larsson H; Bergen SE
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e200
T58. ASSOCIATION OF AUTISM DIAGNOSIS AND POLYGENIC SCORES WITH EATING DISORDER SEVERITY
Zhang R; Birgegard A; Fundin B; Landen M; Thornton L; Bulik C; Dinkler L
Article: EUROPEAN EATING DISORDERS REVIEW. 2022;30(5):442-458
Association of autism diagnosis and polygenic scores with eating disorder severity
Zhang R; Birgegard A; Fundin B; Landen M; Thornton LM; Bulik CM; Dinkler L
Journal article: CIRCULATION. 2022;145(Suppl_1)
Abstract P014: Disordered Eating And Cardiometabolic Risks In Chinese Women: The China Health And Nutrition Survey
Qi B; Zhang R; Yao S; Thornton LM; Howard AG; Gordon-larsen P; Du S; Wang H; Zhang B; Bulik CM; North KE; Munn-Chernoff MA
Article: MOLECULAR PSYCHIATRY. 2022;27(3):1448-1454
Novel disease associations with schizophrenia genetic risk revealed in ∼400,000 UK Biobank participants
Zhang R; Sjolander A; Ploner A; Lu D; Bulik CM; Bergen SE
Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):61
Polygenic association with severity and long-term outcome in eating disorder cases
Johansson T; Birgegard A; Zhang R; Bergen SE; Landen M; Petersen LV; Bulik CM; Hubel C
Article: MOLECULAR PSYCHIATRY. 2021;26(9):5389-5397
Familial co-aggregation of schizophrenia and eating disorders in Sweden and Denmark
Zhang R; Larsen JT; Kuja-Halkola R; Thornton L; Yao S; Larsson H; Lichtenstein P; Petersen LV; Bulik CM; Bergen SE
Article: DIABETES CARE. 2021;44(5):1143-1150
Association and Familial Coaggregation of Type 1 Diabetes and Eating Disorders: A Register-Based Cohort Study in Denmark and Sweden
Tate AE; Liu S; Zhang R; Yilmaz Z; Larsen JT; Petersen LV; Bulik CM; Svensson A-M; Gudbjornsdottir S; Larsson H; Butwicka A; Kuja-Halkola R
Article: HUMAN BRAIN MAPPING. 2021;42(7):2292-2304
Cross-sex shifts in two brain imaging phenotypes and their relation to polygenic scores for same-sex sexual behavior: A study of 18,645 individuals from the UK Biobank
Abe C; Lebedev A; Zhang R; Jonsson L; Bergen SE; Ingvar M; Landen M; Rahman Q
Article: INTERNATIONAL JOURNAL OF EATING DISORDERS. 2021;54(1):24-35
Screen-detected disordered eating and related traits in a large population sample of females in mainland China: China Health and Nutrition Survey
Yao S; Zhang R; Thornton LM; Peat CM; Qi B; Du S; Wang H; Zhang B; Bulik CM
Article: EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES. 2020;29:e131
Risk of eating disorders in international adoptees: a cohort study using Swedish national population registers
Strand M; Zhang R; Thornton LM; Birgegard A; D'Onofrio BM; Bulik CM
Article: TRANSLATIONAL PSYCHIATRY. 2020;10(1):58
Genome-wide study of immune biomarkers in cerebrospinal fluid and serum from patients with bipolar disorder and controls
Zhang R; Song J; Isgren A; Jakobsson J; Blennow K; Sellgren CM; Zetterberg H; Bergen SE; Landen M
Article: MOLECULAR BIOLOGY AND EVOLUTION. 2014;31(8):1994-2003
Neanderthal Origin of the Haplotypes Carrying the Functional Variant Val92Met in the MC1R in Modern Humans
Ding Q; Hu Y; Xu S; Wang C-C; Li H; Zhang R; Yan S; Wang J; Jin L

All other publications

Preprint: MEDRXIV. 2025
Genome-wide association studies of binge eating behaviour and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes
Termorshuizen J; Davies H; Lee S-H; Dennis J; Hübel C; Johnson J; Lu Y; Munn-Chernoff M; Peters T; Qi B; Schaumberg K; Signer R; Singh K; ter Kuile A; Thornton L; Xu J; Yao S; Yilmaz Z; Zhang R; Zvrskovec J; Abdulkadir M; Ayorech Z; Corfield E; Havdahl A; Krebs K; Mack T; Niarchou M; Palviainen T; Sealock J; Baker J; Bergen A; Birgegård A; Perica VB; Bühren K; Burghardt R; Cassina M; Collantoni E; Crowley J; Danner U; Degenhardt F; DeSocio J; Dina C; Dmitrzak-Węglarz M; Duncan L; Egberts K; Foretova L; Giegling I; Gonidakis F; Gordon S; Grove J; Guillaume S; Guintivano J; Hartman A; Hatzikotoulas K; Herms S; Imgart H; Jiménez-Murcia S; Julià A; Kalsi G; Kaminská D; Karhunen L; Kiezebrink K; Kolb T; Larsen J; Li D; Lilenfeld L; Maj M; Mattingsdal M; Meneguzzo P; Miller A; Mitchell K; Monteleone AM; Olsen C; Padyukov L; Pantel J; Parker R; Pinto D; Raevuori A; Ripatti S; Roberts M; Santonastaso P; Savva A; Schmidt U; Schosser A; Seitz J; Slachtova LLS; Slopien A; Sorbi S; Straub P; Szatkiewicz J; Tam F; Tenconi E; Tortorella A; Tsitsika A; van Elburg A; Wagner G; Watson H; Adan RAH; Alfredsson L; Andreassen O; Ask H; Brandt H; Crawford S; Crow S; Davis L; de Zwaan M; Dedoussis G; Dick D; Ehrlich S; Estivill X; Favaro A; Fernández-Aranda F; Fischer K; Forstner A; Gorwood P; Hakonarson H; Hebebrand J; Herpertz-Dahlmann B; Hinney A; Hudson J; Johnson C; Jordan J; Kaplan A; Kaprio J; Karwautz AFK; Kas MJH; Kaye W; Kennedy J; Kennedy M; Keski-Rahkonen A; Kim Y-R; Klump K; Landén M; Le Hellard S; Lehto K; Lissowska J; Maguire S; Martin N; Mattheisen M; Medland S; Micali N; Mitchell J; Monteleone P; Mortensen PB; Nacmias B; Ophoff R; Papezova H; Pedersen N; Petersen L; Rajcsanyi L; Ramoz N; Reichborn-Kjennerud T; Ricca V; Ripke S; Rujescu D; Rybakowski F; Scherer S; Slof-Op ‘t Landt MCT; Sullivan P; Świątkowska B; van Furth E; Wade T; Werge T; Whiteman D; Woodside B; Zipfel S; Eating Disorders Working Group of the Psychiatric ; Estonian Biobank (EstBB); Bulik C; Huckins L; Breen G; Coleman JRI
Preprint: MEDRXIV. 2024
Shared Genetic Architecture Between Eating Disorders, Mental Health Conditions, and Cardiometabolic Diseases: A Comprehensive Population-Wide Study Across Two Countries
Meijsen J; Hu K; Wei D; Aicoboaie S; Davies HL; Zhang R; Lundberg M; Zetterberg R; Pasman J; Ye W; Werge T; Bulik CM; Fang F; Buil A; Micali N
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E126
GENETIC RISK FOR SCHIZOPHRENIA MODIFIES EATING DISORDER CLINICAL PRESENTATIONS
Zhang R; Kuja-Halkola R; Borg S; Leppa V; Thornton L; Bulik C; Bergen S
Doctoral thesis: 2021
Convergent etiology among schizophrenia, eating disorders, and other medical conditions
Zhang R
Preprint: RESEARCH SQUARE. 2021
Polygenic association with severity and long-term outcome in eating disorder cases
Johansson T; Birgegård A; Zhang R; Bergen S; Landén M; Petersen L; Bulik C; Hübel C
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E238-E239
NOVEL DISEASE ASSOCIATIONS WITH SCHIZOPHRENIA GENETIC RISK REVEALED IN ∼400,000 UK BIOBANK PARTICIPANTS
Zhang R; Sjolander A; Ploner A; Lu D; Bulik C; Bergen S
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E112
FAMILIAL LIABILITY FOR ENDOCRINE-METABOLIC DISORDERS AND DEPRESSION
Leone M; Kuja-Halkola R; Skov J; Zhang R; Liu S; Butwicka A; Larsson H; Leval A; Bergen S
Conference publication: BEHAVIOR GENETICS. 2021;51(6):760
Novel Disease Associations with Schizophrenia Genetic Risk Revealed in ∼400,000 UK Biobank Participants
Zhang R; Sjolander A; Ploner A; Lu D; Bulik CM; Bergen SE
Conference publication: BEHAVIOR GENETICS. 2020;50(6):489-490
Association of family history of schizophrenia with clinical features in eating disorders
Zhang R; Kuja-Halkola R; Bulik CM; Bergen SE
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S213
FAMILIAL CO-AGGREGATION OF SCHIZOPHRENIA AND EATING DISORDERS IN SWEDEN AND DENMARK
Zhang R; Larsen JT; Kuja-Halkola R; Petersen L; Bulik C; Bergen S
Conference publication: BEHAVIOR GENETICS. 2019;49(6):489-490
Familial co-aggregation of schizophrenia and eating disorders in Sweden and Denmark
Zhang R; Larsen JT; Kuja-Halkola R; Petersen LV; Bulik C; Bergen S
Conference publication: BEHAVIOR GENETICS. 2019;49(6):530
Extended genetics of eating behavior and disordered eating
Hubel C; Herle M; Zhang R; Larsen JT; Abdulkadir M
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1292-1293
RISK FOR SCHIZOPHRENIA IN INDIVIDUALS WITH EATING DISORDERS AND THEIR RELATIVES
Zhang R; Kuja-Halkola R; Bulik C; Bergen S
Letter: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2015;63(10):2202-2204
Anemia, Physical Function, and Mortality in Long-Lived Individuals Aged 95 and Older: A Population-Based Study
Liu Z-Y; Deng W; Zhang R-Y; Huang J-P; Wang X-F; Qian D-G; Xu J; Jin L; Wang X-F

Grants

Improving the clinical utility of Polygenic Risk Score for Severe Mental Disorders
Karolinska Institutet
1 January 2025 - 31 December 2026
Towards predicting suicidal risk in people with eating disorders: the roles of clinical presentation and genetic risk
Fonden för Psykisk Hälsa
20 October 2024 - 20 October 2025
Improving Polygenic Prediction for Psychiatric Disorders for Clinical Use
Swedish Research Council
1 July 2022 - 30 June 2025

Employments

Postdoctoral Researcher, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2022-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2022
Degree Of Master Of Medical Science 120 Credits, Karolinska Institutet, 2018
Bachelor of Science, Biological Sciences, Fudan University, 2015

About me

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