Roland Fiskesund

Roland Fiskesund

Assistant Professor
Visiting address: NEO Medicinaren 25, HERM plan 7, Hälsovägen 7C (lastkaj), 14157 Huddinge
Postal address: H7 Medicin, Huddinge, H7 Hematologi Höglund Fiskesund, 171 77 Stockholm

About me

  • Medical Doctor and Team leader with focus on Transfusion Medicine and Stem Cell Biology MD PhD, specializing in Clinical Immunology and Transfusion Medicine. Research interests in Transfusion Medicine and Stem Cell Biology. 2003-2009 Karolinska Institutet Medical School 2008-2014 PhD in Immunology at Karolinska Institutet 2013-2015 Medical Internship at Karolinska University Hospital 2015 Postdoctoral studies at professor Thomas Helledays lab at SciLife, Karolinska Institutet 2017-2019 Postdoctoral studies at the Chinese Academy of Medical Sciences, Beijing 2016-2023 Clinical Specialization in Immunology and Transfusion Medicine at Karolinska University Hospital

Research

  • Transfusion Medicine is a clinically important part of modern medicine and research in this field has vast translational potential. Platelet transfusion in thrombocytopenia and erythrocyte transfusion in anemia are well established and routinely used in the clinic. Our main research interest is exploring the concept of neutrophil transfusion to neutropenic patients with antibiotic refractory infections. Neutrophil transfusion is currently utilized sparingly, mainly due to logistical challenges. We are in the process of developing "off-the-shelf" neutrophil concentrates, drastically cutting costs and logistical hassle. Other research areas that we work with include enzymatic conversion of blood groups, citrate metabolism during apheresis treatments, harvesting and processing of stem cell grafts. Our clinic handles the logistics around all Stem Cell Transplantations at Karolinska University Hospital. This setup provides us with access to large amounts of human hematopoietic stem cells from healthy donors as well as cancer patients. We have ethical permit for /ex vivo /culture, running various experiments including sequencing, CRISPR and animal transplantation as well as biobanking them. In my group, we are interested in characterizing the adhesion molecules on stem cells and understanding their role in maintaining stem cells through integrin signaling.

Teaching

  • I teach Transfusion Medicine at Karolinska Institutet to Nursing and Medical students.

Articles

All other publications

Employments

  • Assistant Professor, Department of Medicine, Huddinge, Karolinska Institutet, 2022-2028

Degrees and Education

  • Degree Of Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2014
  • University Medical Degree, Karolinska Institutet, 2009

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