Rodrigo Morales Castro
About me
My research goal is to understand the basis of inflammatory responses during tissue damage at a cellular and molecular level, and specifically investigate how different immune players modulate tissue repair and regeneration. I have specialized in the application of zebrafish models to study in real-time the role of immune cells during tissue damage and regeneration. I joined Karolinska Institutet with the goal of developing new zebrafish models to study in vivo the immunological mechanisms leading to the initiation and treatment of chronic intestinal pathologies, such as Inflammatory bowel disease (IBD). My long-term goal is to address with zebrafish clinically relevant questions which remain challenging due to the limitations of classical animal models or in vitro approaches.
Articles
- Article: MUCOSAL IMMUNOLOGY. 2025;18(4):836-847
- Article: NATURE. 2025;637(8048):1198-1206
- Article: ISCIENCE. 2024;27(12):111406
- Article: NATURE COMMUNICATIONS. 2023;14(1):8402
- Article: EBIOMEDICINE. 2023;94:104691
- Article: IMMUNITY. 2022;55(12):2336-2351.e12
- Article: MUCOSAL IMMUNOLOGY. 2022;15(5):940-951
- Article: MUCOSAL IMMUNOLOGY. 2022;15(3):443-458
- Article: NATURE COMMUNICATIONS. 2022;13(1):828
- Article: DISEASE MODELS & MECHANISMS. 2021;14(12):dmm049104
- Article: CELL REPORTS. 2020;32(5):107979
- Article: REPRODUCTIVE TOXICOLOGY. 2020;93:163-168
- Article: SCIENTIFIC REPORTS. 2020;10(1):2191
- Article: DEVELOPMENTAL NEUROSCIENCE. 2019;41(1-2):112-122
- Article: FRONTIERS IN IMMUNOLOGY. 2019;10:253
- Article: IMMUNOGENETICS. 2017;69(5):341-349
- Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2016;117(8):1880-1889
- Article: IMMUNOLOGY. 2015;146(1):81-88
- Article: IMMUNOBIOLOGY. 2015;220(6):769-774
- Article: IMMUNOLOGY AND CELL BIOLOGY. 2015;93(2):113-119
- Article: PLOS ONE. 2015;10(12):e0144848
- Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2013;11:128
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All other publications
- Preprint: ELSEVIER BV. 2025
- Review: NATURE PROTOCOLS. 2024;19(10):3085-3137
- Preprint: BIORXIV. 2021
- Book chapter: MOLECULAR GENETICS OF INFLAMMATORY BOWEL DISEASE. 2019;p. 47-76
- Review: FRONTIERS IN IMMUNOLOGY. 2015;6:232
- Review: FRONTIERS IN IMMUNOLOGY. 2013;4:405
Grants
- Red blood cells as modulators of inflammation and tissue regenerationÅke Wibergs Stiftelse1 January 2025 - 31 December 2025
- A zebrafish-based platform to study the genetic-environment crosstalk during intestinal inflammation and regenerationMarcus Borgströms Stiftelse1 January 2023 - 31 December 2023
- Developing a zebrafish-based model to study intestinal regeneration in vivoKI Research Foundation1 January 2022 - 31 December 2023
- Using zebrafish to visualize in vivo the genetic-environment crosstalk in the initiation of Inflammatory bowel diseaseMarcus Borgströms Stiftelse1 January 2022 - 31 December 2022
- Addressing the activity of human IBD-risk non-coding regions after exposure to environmental factors in vivoKI Research Foundation1 January 2020 - 31 December 2021
Employments
- Assistant Professor, Department of Laboratory Medicine, Karolinska Institutet, 2024-2028
- Postdoctoral Researcher, Department of Medicine, Karolinska Institutet, 2020-2024