Robert Schnell

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Article: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2026;110(1):136
A katE katG double-knockout E. coli strain eliminates the risk of catalase contamination in recombinant proteins
Scholz AT; Coppo L; Nolan E; Hernandez M; Wang X; Mishra P; Schnell R; Pato ZA; Chen Y; Dagnell M; Andor A; Cheng Q; Arner ESJ
Article: JOURNAL OF NEUROENDOCRINOLOGY. 2026;38(3):e70159
Alk-Fam150b (augmentor α) expression in the paraventricular nucleus of the mouse hypothalamus at molecular resolution, and its sensitivity to acute stress
Gueissaz L; Sideromenos S; Tretiakov EO; Schnell R; Harkany T
Article: FRONTIERS IN IMMUNOLOGY. 2026;17:1739628
Pharmacological inhibition of USP18 improves antibacterial responses and the intracellular control of Mycobacterium tuberculosis in macrophages
Zhang Q; Gong Z; Schnell R; Zhong Y; Geurink PP; Lauschke VM; Xie J; Gastaldello S; Rottenberg ME
Article: ACTA PHYSIOLOGICA. 2025;241(5):e70031
Neuronal activity modulates the expression of secretagogin, a Ca²⁺ sensor protein, during mammalian forebrain development
Hanics J; Tretiakov EO; Romanov RA; Gaspardy A; Hevesi Z; Schnell R; Harkany T; Alpar A
Article: ACS CATALYSIS. 2024;14(16):12359-12371
Mechanism of Two-Component Mono-Oxygenases Involved in Anthracycline 1-Hydroxylation
Wandi BN; Dinis P; Siitonen V; Schneider G; Schnell R; Metsa-Ketela M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(16):e2309211121
A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues
Szodorai E; Hevesi Z; Wagner L; Hoekfelt TGM; Harkany T; Schnell R
Article: ACS CHEMICAL BIOLOGY. 2023;18(4):794-802
Pseudouridine-Modifying Enzymes SapB and SapH Control Entry into the Pseudouridimycin Biosynthetic Pathway
Artukka E; Schnell R; Palmu K; Rosenqvist P; Szodorai E; Niemi J; Virta P; Schneider G; Metsa-Ketela M
Article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2022;228:113976
Lead derivatization of ethyl 6-bromo-2-((dimethylamino)methyl)-5-hydroxy-1-phenyl-1H-indole-3-carboxylate and 5-bromo-2-(thiophene-2-carboxamido) benzoic acid as FabG inhibitors targeting ESKAPE pathogens
Varakala SD; Reshma RS; Schnell R; Dharmarajan S
Article: CELL CHEMICAL BIOLOGY. 2021;28(9):1321-1332.e5
N-Thio-β-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis
Martelli G; Pessatti TB; Steiner EM; Cirillo M; Caso C; Bisognin F; Landreh M; Dal Monte P; Giacomini D; Schnell R
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2021;143(10):3794-3807
Engineering of Ancestors as a Tool to Elucidate Structure, Mechanism, and Specificity of Extant Terpene Cyclase
Schriever K; Saenz-Mendez P; Rudraraju RS; Hendrikse NM; Hudson EP; Biundo A; Schnell R; Syren P-O
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2021;30:115898
A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens
Vella P; Rudraraju RS; Lundback T; Axelsson H; Almqvist H; Vallin M; Schneider G; Schnell R
Article: JOURNAL OF MOLECULAR BIOLOGY. 2018;430(18):3170-3189
Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium
Sun L; Vella P; Schnell R; Polyakova A; Bourenkov G; Li F; Cimdins A; Schneider TR; Lindqvist Y; Galperin MY; Schneider G; Romling U
Article: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 2018;86(9):912-923
The structure of the N-terminal module of the cell wall hydrolase RipA and its role in regulating catalytic activity
Steiner EM; Lyngso J; Guy JE; Bourenkov G; Lindqvist Y; Schneider TR; Pedersen JS; Schneider G; Schnell R
Article: MOLECULAR METABOLISM. 2018;14:108-120
Secretagogin protects Pdx1 from proteasomal degradation to control a transcriptional program required for β cell specification
Malenczyk K; Szodorai E; Schnell R; Lubec G; Szabo G; Hokfelt T; Harkany T
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2017;27(19):4582-4587
Profiling of in vitro activities of urea-based inhibitors against cysteine synthases from Mycobacterium tuberculosis
Brunner K; Steiner EM; Reshma RS; Sriram D; Schnell R; Schneider G
Article: EMBO JOURNAL. 2017;36(14):2107-2125
A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover
Malenczyk K; Girach F; Szodorai E; Storm P; Segerstolpe A; Tortoriello G; Schnell R; Mulder J; Romanov RA; Borok E; Piscitelli F; Di Marzo V; Szabo G; Sandberg R; Kubicek S; Lubec G; Hokfelt T; Wagner L; Groop L; Harkany T
Article: FEBS JOURNAL. 2017;284(5):725-741
Binding and processing of β-lactam antibiotics by the transpeptidase Ldt_Mt2 from Mycobacterium tuberculosis
Steiner EM; Schneider G; Schnell R
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2016;59(14):6848-6859
Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis
Brunner K; Maric S; Reshma RS; Almqvist H; Seashore-Ludlow B; Gustavsson A-L; Poyraz O; Yogeeswari P; Lundback T; Vallin M; Sriram D; Schnell R; Schneider G
Article: ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS. 2016;72(Pt 2):105-111
Crystal structure of the flavoenzyme PA4991 from Pseudomonas aeruginosa
Jacewicz A; Schnell R; Lindqvist Y; Schneider G
Article: ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS. 2015;71(Pt 8):1020-1026
Structures of Pseudomonas aeruginosa-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion and a ligand-binding site that is an artefact of the crystal form
Baum B; Lecker LSM; Zoltner M; Jaenicke E; Schnell R; Hunter WN; Brenk R
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Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1854(9):1175-1183
Pyridoxal-phosphate dependent mycobacterial cysteine synthases: Structure, mechanism and potential as drug targets
Schnell R; Sriram D; Schneider G
Corrigendum: PLOS ONE. 2015;10(4):e0127016
Crystal Structures of the Kinase Domain of the Sulfate-Activating Complex in Mycobacterium tuberculosis (vol 10, e0121494, 2015)
Poyraz O; Brunner K; Lohkamp B; Axelsson H; Hammarstroem LGJ; Schnell R
Corrigendum: ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY. 2006;62:1571
Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens (vol 62, pg 1196, 2006)
Fogg MJ; Alzari P; Bahar M; Bertini I; Betton J-M; Burmeister WP; Cambillau C; Canard B; Carrondo MA; Coll M; Daenke S; Dym O; Egloff M-P; Enguita FJ; Geerlof A; Haouz A; Jones TA; Qingjun M; Manicka SN; Migliardi M; Nordlund P; Owens RJ; Peleg Y; Schneider G; Schnell R; Stuart DI; Tarbouriech N; Unge T; Wilkinson AJ; Wilmanns M; Wilson KS; Zimhony O; Grimes JM

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