Rickard Linder

Publications
CV
Public outreach and news

Articles

Article: CARDIOVASCULAR REVASCULARIZATION MEDICINE. 2024;66:43-50

Bivalirudin versus heparin in ST and non-ST-segment elevation myocardial infarction-Outcomes at two years.

Omerovic E; James S; Råmundal T; Fröbert O; Linder R; Danielewicz M; Hamid M; Pagonis C; Henareh L; Wagner H; Stewart J; Jensen J; Lindros P; Robertsson L; Wikström H; Ulvenstam A; Bhiladval P; Tödt T; Ioanes D; Kellerth T; Zagozdzon L; Götberg M; Andersson J; Angerås O; Östlund O; Held C; Koul S; Erlinge D
Article: RESUSCITATION PLUS. 2024;18:100596

Implementation of an extracorporeal resuscitation (ECPR) program for out-of-hospital cardiac arrest in Stockholm, Sweden: Feasibility, safety, and outcome

Abazi LF; Liliequist A; Bohm F; Hedberg M; Simonsson M; Backman A; Ax M; Braunschweig F; Mellbin L; Linder R; Svensson L; Jurga J; Nordberg P; Ringh M; Forsberg S; Hollenberg J
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2024;390(16):1481-1492

FFR-Guided Complete or Culprit-Only PCI in Patients with Myocardial Infarction

Bohm F; Mogensen B; Engstrom T; Stankovic G; Srdanovic I; Lonborg J; Zwackman S; Hamid M; Kellerth T; Lauermann J; Kajander OA; Andersson J; Linder R; Angeras O; Renlund H; Erglis A; Menon M; Schultz C; Laine M; Held C; Ruck A; Ostlund O; James S
Journal article: JACC: CASE REPORTS. 2024;29(3):102192

Mind the Gap in TAVR: Recognizing and Managing Misloaded Self-Expanding TAVR Devices.

Omar A; Damlin A; Rück A; Settergren M; Verouhis D; Linder R; Meduri CU; Saleh N
Article: AMERICAN JOURNAL OF EMERGENCY MEDICINE. 2023;74:104-111

HEART-score can be simplified without loss of discriminatory power in patients with chest pain - Introducing the HET-score

Lofmark H; Muhrbeck J; Eggers KM; Linder R; Ljung L; Martinsson A; Melki D; Sarkar N; Svensson P; Lindahl B; Jernberg T
Article: EUROPEAN HEART JOURNAL. 2023;44(30):2833-2842

PCI or CABG for left main coronary artery disease: the SWEDEHEART registry

Persson J; Yan J; Angeras O; Venetsanos D; Jeppsson A; Sjogren I; Linder R; Erlinge D; Ivert T; Omerovic E
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2023;377:26-32

Reducing cardiac tamponade caused by temporary pacemaker perforation in transcatheter aortic valve replacement*

Feldt K; Dalen M; Meduri CU; Kastengren M; Bager J; Hornsten J; Omar A; Ruck A; Saleh N; Linder R; Settergren M
Article: JACC-CARDIOVASCULAR INTERVENTIONS. 2023;16(6):670-677

Commissural Alignment With ACURATE neo2 Valve in an Unselected Population

Meduri CU; Ruck A; Linder R; Verouhis D; Settergren M; Sorajja A; Daher D; Saleh N
Article: HEART RHYTHM O2. 2023;4(3):200-206

Prognostic value of early sustained ventricular arrhythmias in ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention: A substudy of VALIDATE-SWEDEHEART trial

Demidova MM; Rylance R; Koul S; Dworeck C; James S; Aasa M; Hamid M; Swahn E; Hambraeus K; Danielewicz M; Linder R; Frobert O; Grimfjard P; Stewart J; Henareh L; Andersson J; Wagner H; Erlinge D; Platonov PG
Article: LAKARTIDNINGEN. 2023;120:22129

[More coronary computed tomography angiographies and less exercise electrocardiograms in patients under investigation for coronary artery disease?].

Löfmark H; Brandberg H; Ostenfeld E; Sarno G; Linder R
Article: AMERICAN HEART JOURNAL. 2023;255:39-51

Routine revascularization with percutaneous coronar y intervention in patients with coronary artery disease undergoing transcatheter aortic valve implantation - the third nordic aortic valve intervention trial - NOTION-3

Sabbah M; Veien K; Niemela M; Freeman P; Linder R; Ioanes D; Terkelsen CJ; Kajander OA; Koul S; Savontaus M; Karjalainen P; Erglis A; Minkkinen M; Jorgensen T; Sondergaard L; De Backer O; Engstrom T; Lonborg J
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2022;359:7-13

Percutaneous plug-based vascular closure device in 1000 consecutive transfemoral transcatheter aortic valve implantations

Kastengren M; Settergren M; Ruck A; Feldt K; Saleh N; Linder R; Verouhis D; Meduri CU; Bager J; Dalen M
Article: CIRCULATION-CARDIOVASCULAR INTERVENTIONS. 2021;14(12):e008969

Bivalirudin Versus Heparin Monotherapy in ST-Segment-Elevation Myocardial Infarction

James S; Koul S; Andersson J; Angeras O; Bhiladvala P; Calais F; Danielewicz M; Frobert O; Grimfjard P; Gotberg M; Henareh L; Ioanes D; Jensen J; Linder R; Lindroos P; Omerovic E; Panayi G; Ramunddal T; Sarno G; Ulvenstam A; Voltz S; Wagner H; Wikstrom H; Ostlund O; Erlinge D
Article: OPEN HEART. 2021;8(2):e001703

Transcatheter aortic valve replacement using the iSleeve expandable sheath in small femoral arteries

Glaser N; O'Sullivan CJ; Saleh N; Verouhis D; Settergren M; Linder R; Ruck A
Article: CARDIOLOGY. 2021;146(4):409-418

Age-Stratified Outcome in Treatment of Left Main Coronary Artery Stenosis: A NOBLE Trial Substudy.

Steigen T; Holm NR; Myrmel T; Endresen PC; Trovik T; Mäkikallio T; Lindsay M; Spence MS; Erglis A; Menown IBA; Kumsars I; Kellerth T; Davidavičius G; Linder R; Anttila V; Juul Hune Mogensen L; Hostrup Nielsen P; Graham ANJ; Hildick-Smith D; Thuesen L; Christiansen EH; NOBLE Study Investigators
Article: RMD OPEN. 2020;6(3):e001463

Is rheumatoid arthritis a risk factor for acute coronary syndrome also among individuals at elevated risk, such as individuals presenting with acute chest pain?

Svensson P; Bergstrom M; Discacciati A; Ljung L; Jernberg T; Frick M; Linder R; Askling J
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2020;317:1-6

Blood haemoglobin, renal insufficiency, fractional flow reserve and plasma NT-proBNP is associated with index of microcirculatory resistance in chronic coronary syndrome

Ostlund-Papadogeorgos N; Ekenback C; Jokhaji F; Mir-Akbari H; Witt N; Jernberg T; Wallen H; Linder R; Tornerud M; Samad BA; Persson J
Article: EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE. 2020;9(7):741-747

Family history of coronary artery disease is associated with acute coronary syndrome in 28,188 chest pain patients

Wahrenberg A; Magnusson PKE; Discacciati A; Ljung L; Jernberg T; Frick M; Linder R; Svensson P
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2020;75(22):2785-2799

Survival of Patients With Angina Pectoris Undergoing Percutaneous Coronary Intervention With Intracoronary Pressure Wire Guidance

Volz S; Dworeck C; Redfors B; Petursson P; Angeras O; Gan L-M; Gotberg M; Sarno G; Venetsanos D; Grimfard P; Hofmann R; Jensen J; Bjorklund F; Danielewicz M; Linder R; Ramunddal T; Frobert O; Witt N; James S; Erlinge D; Omerovic E
Article: EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE. 2020;9(4):323-332

Radial artery access is associated with lower mortality in patients undergoing primary PCI: a report from the SWEDEHEART registry

Dworeck C; Redfors B; Volz S; Haraldsson I; Angeras O; Ramunddal T; Ioanes D; Myredal A; Odenstedt J; Hirlekar G; Koul S; Frobert O; Linder R; Venetsanos D; Hofmann R; Ulvenstam A; Petursson P; Sarno G; James S; Erlinge D; Omerovic E
Article: LANCET. 2020;395(10219):191-199

Percutaneous coronary angioplasty versus coronary artery bypass grafting in the treatment of unprotected left main stenosis: updated 5-year outcomes from the randomised, non-inferiority NOBLE trial

Holm NR; Makikallio T; Lindsay MM; Spence MS; Erglis A; Menown IBA; Trovik T; Kellerth T; Kalinauskas G; Mogensen LJH; Nielsen PH; Niemela M; Lassen JF; Oldroyd K; Berg G; Stradins P; Walsh SJ; Graham ANJ; Endresen PC; Frobert O; Trivedi U; Anttila V; Hildick-Smith D; Thuesen L; Christiansen EH; Jensen LO; Margus S; Kervinen K; Eskola M; Kajander O; Romppanen H; Hartikainen J; Pentikainen MO; Kumsars I; Steigen TK; Hervold A; Eriksen E; Linder RBA; Corbascio M; Hanratty CG; Banning A; Zaman A; Cotton J
Article: JOURNAL OF INTERVENTIONAL CARDIOLOGY. 2019;2019:1397895-6

Changes in Index of Microcirculatory Resistance during PCI in the Left Anterior Descending Coronary Artery in Relation to Total Length of Implanted Stents

Ekenback C; Jokhaji F; Ostlund-Papadogeorgos N; Mir-Akbari H; Linder R; Witt N; Tornerud M; Samad B; Persson J
Article: EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE. 2019;8(6):510-519

Radial versus femoral access in patients with acute coronary syndrome undergoing invasive management: A prespecified subgroup analysis from VALIDATE-SWEDEHEART

Volz S; Angeras O; Koul S; Haraldsson I; Sarno G; Venetsanos D; Grimfard P; Ulvenstam A; Hofmann R; Hamid M; Henareh L; Wagner H; Jensen J; Danielewicz M; Ostlund O; Eriksson P; Schersten F; Linder R; Ramunddal T; Petursson P; Frobert O; James S; Erlinge D; Omerovic E
Article: EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE. 2019;8(6):492-501

Editor's Choice- Bivalirudin versus heparin monotherapy in non-ST-segment elevation myocardial infarction

Erlinge D; Koul S; Omerovic E; Frobert O; Linder R; Danielewicz M; Hamid M; Venetsanos D; Henareh L; Pettersson B; Wagner H; Grimfjard P; Jensen J; Hofmann R; Ulvenstam A; Volz S; Petursson P; Ostlund O; Sarno G; Wallentin L; Schersten F; Eriksson P; James S
Article: EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE. 2019;8(6):502-509

Sex-related response to bivalirudin and unfractionated heparin in patients with acute myocardial infarction undergoing percutaneous coronary intervention: A subgroup analysis of the VALIDATE-SWEDEHEART trial

Venetsanos D; Lawesson SS; Frobert O; Omerovic E; Henareh L; Robertsson L; Linder R; Gotberg M; James S; Alfredsson J; Erlinge D; Swahn E
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2019;284:6-11

Sensitivity of undetectable level of high-sensitivity troponin T at presentation in a large non-ST-segment elevation myocardial infarction cohort of early presenters

Ljung L; Reichard C; Hagerman P; Eggers KM; Frick M; Lindahl B; Linder R; Martinsson A; Melki D; Svensson P; Jernberg T
Article: ANNALS OF EMERGENCY MEDICINE. 2019;73(5):491-499

A Rule-Out Strategy Based on High-Sensitivity Troponin and HEART Score Reduces Hospital Admissions

Ljung L; Lindahl B; Eggers KM; Frick M; Linder R; Lofmark HB; Martinsson A; Melki D; Sarkar N; Svensson P; Jernberg T
Article: EUROINTERVENTION. 2018;14(12):e1269-e1275

Transcatheter aortic valve implantation using the ACURATE neo in bicuspid and tricuspid aortic valve stenosis: a propensity-matched analysis of a European experience

Mangieri A; Chieffo A; Won-Keun K; Stefanini GG; Rescigno G; Barbanti M; Tamburino C; Ruck A; Pagnesi M; Linder R; Toggweiler S; Montorfano M; Colombo A
Article: CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. 2018;92(5):954-961

Impact of percutaneous femoral arteriotomy closure using the MANTA^TM device on vascular and bleeding complications after transcatheter aortic valve replacement

De Palma R; Settergren M; Ruck A; Linder R; Saleh N
Article: JACC-CARDIOVASCULAR INTERVENTIONS. 2018;11(16):1590-1597

The Analgesic Effect of Oxygen in Suspected Acute Myocardial Infarction A Substudy of the DETO2X-AMI Trial

Sparv D; Hofmann R; Gunnarsson A; James S; Hedberg C; Lauermann J; Torild P; Omerovic E; Bergstrom K; Haugen E; Bergstrom C; Linder R; Borg P; Haaga U; Olsson A; Boving E; Ostlund O; Rylance R; Witt N; Erlinge D
Article: EUROPEAN HEART JOURNAL. 2018;39(29):2730-2739

Oxygen therapy in ST-elevation myocardial infarction

Hofmann R; Witt N; Lagerqvist B; Jernberg T; Lindahl B; Erlinge D; Herlitz J; Alfredsson J; Linder R; Omerovic E; Angeras O; Venetsanos D; Kellerth T; Sparv D; Lauermann J; Barmano N; Verouhis D; Ostlund O; Svensson L; James SK
Article: SCANDINAVIAN CARDIOVASCULAR JOURNAL. 2018;52(2):100-107

Outcome and selection of revascularization strategy in left main coronary artery stenosis

Gripenberg T; Jokhaji F; Ostlund-Papadogeorgos N; Ekenback C; Linder R; Samad B; Persson J
Article: OBESITY RESEARCH & CLINICAL PRACTICE. 2018;12(1):51-60

The obesity paradox: An analysis of pre-procedure weight trajectory on survival outcomes in patients undergoing transcatheter aortic valve implantation

De Palma R; Ivarsson J; Feldt K; Saleh N; Ruck A; Linder R; Settergren M
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2017;377(13):1240-1249

Oxygen Therapy in Suspected Acute Myocardial Infarction

Hofmann R; James SK; Jernberg T; Lindahl B; Erlinge D; Witt N; Arefalk G; Frick M; Alfredsson J; Nilsson L; Ravn-Fischer A; Omerovic E; Kellerth T; Sparv D; Ekelund U; Linder R; Ekstrom M; Lauermann J; Haaga U; Pernow J; Ostlund O; Herlitz J; Svensson L
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2017;377(12):1132-1142

Bivalirudin versus Heparin Monotherapy in Myocardial Infarction

Erlinge D; Omerovic E; Frobert O; Linder R; Danielewicz M; Hamid M; Swahn E; Henareh L; Wagner H; Hardhammar P; Sjogren I; Stewart J; Grimfjard P; Jensen J; Aasa M; Robertsson L; Lindroos P; Haupt J; Wikstrom H; Ulvenstam A; Bhiladvala P; Lindvall B; Lundin A; Todt T; Ioanes D; Ramunddal T; Kellerth T; Zagozdzon L; Gotberg M; Andersson J; Angeras O; Ostlund O; Lagerqvist B; Held C; Wallentin L; Schersten F; Eriksson P; Koul S; James S
Article: HEART. 2017;103(2):125-131

An algorithm for rule-in and rule-out of acute myocardial infarction using a novel troponin I assay

Lindahl B; Jernberg T; Badertscher P; Boeddinghaus J; Eggers KM; Frick M; Rubini Gimenez M; Linder R; Ljung L; Martinsson A; Melki D; Nestelberger T; Rentsch K; Reichlin T; Sabti Z; Schubera M; Svensson P; Twerenbold R; Wildi K; Mueller C
Article: LANCET. 2016;388(10061):2743-2752

Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis (NOBLE): a prospective, randomised, open-label, non-inferiority trial

Makikallio T; Holm NR; Lindsay M; Spence MS; Erglis A; Menown IBA; Trovik T; Eskola M; Romppanen H; Kellerth T; Ravkilde J; Jensen LO; Kalinauskas G; Linder RBA; Pentikainen M; Hervold A; Banning A; Zaman A; Cotton J; Eriksen E; Margus S; Sorensen HT; Nielsen PH; Niemela M; Kervinen K; Lassen JF; Maeng M; Oldroyd K; Berg G; Walsh SJ; Hanratty CG; Kumsars I; Stradins P; Steigen TK; Frobert O; Graham ANJ; Endresen PC; Corbascio M; Kajander O; Trivedi U; Hartikainen J; Anttila V; Hildick-Smith D; Thuesen L; Christiansen EH
Article: AMERICAN HEART JOURNAL. 2016;175:36-46

Bivalirudin versus heparin in non-ST and ST-segment elevation myocardial infarction-a registry-based randomized clinical trial in the SWEDEHEART registry (the VALIDATE-SWEDEHEART trial)

Erlinge D; Koul S; Eriksson P; Schersten F; Omerovic E; Linder R; Ostlund OP; Wallentin L; Frobert O; James S
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2014;371(12):1111-1120

Outcomes 1 Year after Thrombus Aspiration for Myocardial Infarction

Lagerqvist B; Frobert O; Olivecrona GK; Gudnason T; Maeng M; Alstrom P; Andersson J; Calais F; Carlsson J; Collste O; Gotberg M; Hardhammar P; Ioanes D; Kallryd A; Linder R; Lundin A; Odenstedt J; Omerovic E; Puskar V; Todt T; Zelleroth E; Ostlund O; James SK
Article: CLINICAL RESEARCH IN CARDIOLOGY. 2007;96(2):86-93

Is late stent thrombosis in drug-eluting stents a real clinical issue? A single-center experience and review of the literature.

Carlsson J; von Wagenheim B; Linder R; Anwari TM; Qvist J; Petersson I; Magounakis T; Lagerqvist B
Article: LAKARTIDNINGEN. 2006;103(34):2390-2392

[Life-saving mechanical compression during percutaneous coronary intervention].

Linder R; Abdollahi P; Wennersten G
Article: THROMBOSIS AND HAEMOSTASIS. 2004;91(2):381-387

Myocardial damage, coagulation activity and the response to thrombin inhibition in unstable coronary artery disease

Oldgren J; Siegbahn A; Grip L; Linder R; Thygesen K; Wallentin L
Article: THROMBOSIS RESEARCH. 2003;110(4):221-226

The influence of direct and antithrombin-dependent thrombin inhibitors on the procoagulant and anticoagulant effects of thrombin

Linder R; Frebelius S; Grip L; Swedenborg J
Article: BLOOD COAGULATION & FIBRINOLYSIS. 2003;14(2):139-146

Inhibition of endothelial cell-mediated generation of activated protein C by direct and antithrombin-dependent thrombin inhibitors

Linder R; Frebelius S; Jansson K; Swedenborg J
Article: EUROPEAN HEART JOURNAL. 2003;24(1):86-93

Myocardial damage, inflammation and thrombin inhibition in unstable coronary artery disease

Oldgren J; Wallentin L; Grip L; Linder R; Norgaard BL; Siegbahn A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2001;21(6):1059-1064

Coagulation activity and clinical outcome in unstable coronary artery disease

Oldgren J; Linder R; Grip L; Siegbahn A; Wallentin L
Article: EUROPEAN HEART JOURNAL. 1999;20(22):1657-1666

Activated partial thromboplastin time and clinical outcome after thrombin inhibition in unstable coronary artery disease

Oldgren J; Linder R; Grip L; Siegbahn A; Wallentin L
Article: THROMBOSIS RESEARCH. 1999;95(2):117-125

Thrombin inhibitors suppress the thrombin-thrombomodulin-mediated generation of activated protein C

Linder R; Blombäck M; Egberg N; Grip L
Article: EUROPEAN HEART JOURNAL. 1999;20(7):506-518

The effect of a low molecular mass thrombin inhibitor, inogatran, and heparin on thrombin generation and fibrin turnover in patients with unstable coronary artery disease

Linder R; Oldgren J; Egberg N; Grip L; Larson G; Siegbahn A; Wallentin L
Article: EUROPEAN HEART JOURNAL. 1997;18(9):1416-1425

A low molecular weight, selective thrombin inhibitor, inogatran, vs heparin, in unstable coronary artery disease in 1209 patients. A double-blind, randomized, dose-finding study. Thrombin inhibition in Myocardial Ischaemia (TRIM) study group.
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All other publications

Other: JACC: CASE REPORTS. 2023;11:101777

BASILICA Procedure Prior to Valve-in-Valve TAVR in a Supra-Annular TAV Prosthesis.

Damlin A; Meduri C; Manouras A; Verouhis D; Linder R; Rück A; Settergren M
Editorial comment: EUROINTERVENTION. 2020;16(3):266-268

Percutaneous access and closure using the MANTA vascular closure device in transaxillary transcatheter aortic valve implantation

Ruck A; Eriksson D; Verouhis D; Saleh N; Linder R; Corbascio M; Settergren M
Review: LAKARTIDNINGEN. 2011;108(18):988-991

[Thrombocytosis of mechanical prosthetic heart valves is al life-threatening condition. Thrombocyte inhibition possible as treatment and prevention].

Stenudd J; Linder R
Letter: CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. 2010;76(5):779

Rebuttal: Dissection, Occlusion and Spasm; Myths Involving Sheathless Guide Catheters

Linder R; Puri A; Liang M
Review: LAKARTIDNINGEN. 2006;103(39):2845-2847

[Drug-eluting stents can increase the risk of late stent thrombosis].

Skyttberg N; Linder R; Carlsson J
Thesis / dissertation: 2002

The effect of thrombin inhibitors on coagulation activity and generation of activated protein C

Linder, Rikard
Letter: CLINICAL CHEMISTRY. 1996;42(9):1488-1489

Bedside heparin monitoring by activated partial thromboplastin time measured with a dry reagent

Linder R; Grip L; Olason E; Blomback M

Employments

Affiliated to Research, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2023-2025

Degrees and Education

Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2002

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