Rasmus Berglund

About me
Publications
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About me

Im a Post-doc in Maja Jagodic´s neuroimmunology unit and a resident
physician at the neurology clinic at Karolinska hospital.
SSMF Post doc fellow 2022-2025
Hjärnfonden Post doc fellow 2025-2028
M.D Karolinska institutet 2005-2012
Ph.D Karolinska institutet, CNS, neuroimmunology 2012-2021

Research

My main focus is on the role of microglial cells in chronic CNS inflammation
such as progressive multiple sclerosis. I'm interested in functional
microglial phenotypes and how these are affected by environment and
treatments, and how we can utilize this to benefit patients. During my PhD, I
studied the protective microglial function in clearing and degrading debris
through autophagy in experimental MS models. My aim during my post-doc is to
translate these findings to human disease.

Articles

Article: NATURE COMMUNICATIONS. 2024;15(1):383
The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34
Berglund R; Cheng Y; Piket E; Adzemovic MZ; Zeitelhofer M; Olsson T; Guerreiro-Cacais AO; Jagodic M
Article: FRONTIERS IN NEUROLOGY. 2020;11:600401
Effect of Vitamin D on Experimental Autoimmune Neuroinflammation Is Dependent on Haplotypes Comprising Naturally Occurring Allelic Variants of CIITA (Mhc2ta)
Hochmeister S; Aeinehband S; Dorris C; Berglund R; Haindl MT; Velikic V; Gustafsson SA; Olsson T; Piehl F; Jagodic M; Zeitelhofer M; Adzemovic MZ
Article: SCIENCE IMMUNOLOGY. 2020;5(52):eabb5077
Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation.
Berglund R; Guerreiro-Cacais AO; Adzemovic MZ; Zeitelhofer M; Lund H; Ewing E; Ruhrmann S; Nutma E; Parsa R; Thessen-Hedreul M; Amor S; Harris RA; Olsson T; Jagodic M
Article: NATURE IMMUNOLOGY. 2018;19(5):1-7
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling
Lund H; Pieber M; Parsa R; Grommisch D; Ewing E; Kular L; Han J; Zhu K; Nijssen J; Hedlund E; Needhamsen M; Ruhrmann S; Guerreiro-Cacais AO; Berglund R; Forteza MJ; Ketelhuth DFJ; Butovsky O; Jagodic M; Zhang X-M; Harris RA
Article: GENES AND IMMUNITY. 2017;18(1):48-56
VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis
Guerreiro-Cacais AO; Norin U; Gyllenberg A; Berglund R; Beyeen AD; Petit-Teixeira E; Cornelis F; Saoudi A; Fournie GJ; Holmdahl R; Alfredsson L; Klareskog L; Jagodic M; Olsson T; Kockum I; Padyukov L
Article: NEUROBIOLOGY OF DISEASE. 2014;71:220-233
Acute treatment with valproic acid and L-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats
Castelo-Branco G; Stridh P; Guerreiro-Cacais AO; Adzemovic MZ; Falcao AM; Marta M; Berglund R; Gillett A; Hamza KH; Lassmann H; Hermanson O; Jagodic M

All other publications

Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2024;30(3):69
The emergence of a microglial population in the aging central nervous system serves as a protective mechanism against experimental neuroinflammation
Berglund R; Cheng Y; Piket E; Adzemovic M; Zeitelhofer M; Olsson T; Cacais AOG; Jagodic M
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2024;30(3):882
The impact of BTK inhibitors on human microglia and macrophages
Cheng Y; Berglund R; Carl S; Jagodic M
Conference publication: GLIA. 2023;71:E828
The aging CNS is protected by an autophagy-dependent microglia population promoted by IL-34
Berglund R
Doctoral thesis: 2021
Microglia : health promoting pathways and therapeutic targets in ageing and neuroinflammation
Berglund R
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):296
Autophagy associated pathways regulate degradation of myelin debris and microglial phenotypes to determine clinical outcome of neuroinflammation
Berglund R; Guerreiro-Cacais AO; Ruhrmann S; Hedreul MT; Khademi M; Jagodic M; Olsson T
Corrigendum: GENES AND IMMUNITY. 2017;18(2):109
VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis (vol 18, pg 48, 2017)
Guerreiro-Cacais AO; Norin U; Gyllenberg A; Berglund R; Beyeen AD; Petit-Teixeira E; Cornelis F; Saoudi A; Fournie GJ; Holmdahl R; Alfredsson L; Klareskog L; Jagodic M; Olsson T; Kockum I; Padyukov L
Conference publication: JOURNAL OF NEUROIMMUNOLOGY. 2014;275(1-2):136-137
A novel connection of autophagy related gene 7 to multiple sclerosis and experimental autoimmune encephalomyelitis
Berglund R; Hedreul MT; Parsa R; Bergman P; Jagodic M; Olsson T; Cacais AOG; Link J; Khademi M; Kockum I; Becher J; Cecconi F
Meeting abstract: JOURNAL OF NEUROIMMUNOLOGY. 2014;275(1-2):205
VAV1 controls inflammation in Experimental Autoimmune Encephalomyelitis (EAE)
Guerreiro-Cacais AO; N'diaye M; Berglund R; Beyeen AD; Jagodic M; Olsson T
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2014;79(6):449
A Novel Connection of Autophagy-Related Gene 7 to Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
Berglund R; Olsson T; Jagodic M; Hedreul MT; Parsa R
Conference publication: JOURNAL OF NEUROIMMUNOLOGY. 2012;253(1-2):81-82
Mapping genome-wide expression in experimental autoimmune encephalomyelitis highlights disease correlated gene networks and positional candidate genes regulating autoimmunity
Hedreul MT; Moller S; Stridh P; Berglund R; Guerreiro-Cacais AO; Grimm A-K; Gupta Y; Ockinger J; Gillett A; Beyeen AD; Diez M; Olsson T; Jagodic M
Conference publication: JOURNAL OF NEUROIMMUNOLOGY. 2012;253(1-2):88-89
Variations in autophagy related gene Atg7 expression correlate to disease phenotypes in multiple sclerosis and experimental autoimmune encephalomyelitis
Berglund MTH; Berglund RB; Link J; Parsa R; Becher J; Bergman P; Khademi M; Cecconi F; Hillert J; Kockum I; Jagodic M; Olsson T

Employments

Postdoctoral Researcher, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2026
Clinical Assistant, Department of Clinical Neuroscience, Karolinska Institutet, 2021-2024

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2021
University Medical Degree, Karolinska Institutet, 2012

About me

Research

Articles

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Degrees and Education

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