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Patrick Sullivan

Professor

About me

Dr. Sullivan is a Professor of Psychiatric Genetics at the Karolinska Institute in the Department of Medical Epidemiology and Biostatistics. He is also the Yeargan Distinguished Professor in the Department of Genetics and Psychiatry at the University of North Carolina at Chapel Hill. His lab investigates the molecular genetics of schizophrenia, major depressive disorder (including post-partum depression), eating disorders, and autism. Dr. Sullivan is a founder and the lead principal investigator of the Psychiatric Genomics Consortium, the largest consortium in the history of psychiatry. He is involved in a wide range of genomic studies of human diseases and has multiple NIH grants. At Karolinska Institutet Dr Sullivan is responsible for the KI Psychiatric Genomics Institute - a systematic program established to evaluate the epidemiological, molecular, and cellular effects of genetic risk loci for psychiatric disorders. Dr. Sullivan has published over 320 papers and 40 reviews/chapters.

Research description

Selected publications

Publications

A Comprehensive Analysis of Nuclear-Encoded Mitochondrial Genes in Schizophrenia
Gonçalves Vf, Cappi C, Hagen Cm, Sequeira A, Vawter Mp, Derkach A, et al
Biological psychiatry 2018;83(9):780-789

Adverse life events increase risk for postpartum psychiatric episodes: A population-based epidemiologic study
Meltzer-brody S, Larsen Jt, Petersen L, Guintivano J, Florio Ad, Miller Wc, et al
Depression and anxiety 2018;35(2):160-167

Adverse life events, psychiatric history, and biological predictors of postpartum depression in an ethnically diverse sample of postpartum women
Guintivano J, Sullivan Pf, Stuebe Am, Penders T, Thorp J, Rubinow Dr, et al
Psychological medicine 2018;48(7):1190-1200

Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals
Coleman Jri, Bryois J, Gaspar Ha, Jansen Pr, Savage Je, Skene N, et al
Molecular psychiatry 2018;():-

Comparative genomic evidence for the involvement of schizophrenia risk genes in antipsychotic effects
Kim Y, Giusti-rodriguez P, Crowley Jj, Bryois J, Nonneman Rj, Ryan Ak, et al
Molecular psychiatry 2018;23(3):708-712

Conference Report: Psychiatric Genomics Consortium Meeting: Pathways to Drugs, London, March 2017
Gaspar Ha, Collier Da, Geschwind Dh, Lewis Cm, Li Q, Roth Bl, et al
Biological psychiatry 2018;84(6):e49-e50

Developmental Delay, Treatment-Resistant Psychosis, and Early-Onset Dementia in a Man With 22q11 Deletion Syndrome and Huntington's Disease
Farrell M, Lichtenstein M, Crowley Jj, Filmyer Dm, Lázaro-muñoz G, Shaughnessy Ra, et al
The American journal of psychiatry 2018;175(5):400-407

Examining the role of common and rare mitochondrial variants in schizophrenia
Gonçalves Vf, Giamberardino Sn, Crowley Jj, Vawter Mp, Saxena R, Bulik Cm, et al
PloS one 2018;13(1):e0191153-

Familiality of Psychiatric Disorders and Risk of Postpartum Psychiatric Episodes: A Population-Based Cohort Study
Bauer Ae, Maegbaek Ml, Liu X, Wray Nr, Sullivan Pf, Miller Wc, et al
The American journal of psychiatry 2018;175(8):783-791

Genetic risk scores and family history as predictors of schizophrenia in Nordic registers
Lu Y, Pouget Jg, Andreassen Oa, Djurovic S, Esko T, Hultman Cm, et al
Psychological medicine 2018;48(7):1201-1208

Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes
Stokowy T, Polushina T, Sønderby Ie, Karlsson R, Giddaluru S, Le Hellard S, et al
Scientific reports 2018;8(1):6915-

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Major Depressive Disorder Working Group Of The Psychiatric Genomics Consortium, Eqtlgen, 23andme, Wray Nr, Ripke S, Mattheisen M, et al
Nature genetics 2018;50(5):668-681

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
23andme Research Team, Howard Dm, Adams Mj, Shirali M, Clarke Tk, Marioni Re, et al
Nature communications 2018;9(1):1470-

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia (vol 22, pg 1502, 2017)
Clozapine-induced Agranulocytosis, Legge Se, Hamshere Ml, Ripke S, Pardinas Af, Goldstein Ji, et al
MOLECULAR PSYCHIATRY 2018;23(1):162-163

Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD
Major Depressive Disorder Working Group Of The Psychiatric Genomics Consortium, Van Der Auwera S, Peyrot Wj, Milaneschi Y, Hertel J, Baune B, et al
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2018;177(1):40-49

Improved ethical guidance for the return of results from psychiatric genomics research
Lázaro-muñoz G, Farrell Ms, Crowley Jj, Filmyer Dm, Shaughnessy Ra, Josiassen Rc, et al
Molecular psychiatry 2018;23(1):15-23

Inference on phenotype-specific effects of genes using multivariate kernel machine regression
Maity A, Zhao J, Sullivan Pf, Tzeng Jy
GENETIC EPIDEMIOLOGY 2018;42(1):64-79

Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa
Eating Disorder Working Group Of The Psychiatric Genomics Consortium, Huckins Lm, Hatzikotoulas K, Southam L, Thornton Lm, Steinberg J, et al
Molecular psychiatry 2018;23(5):1169-1180

MIR137 schizophrenia-associated locus controls synaptic function by regulating synaptogenesis, synapse maturation and synaptic transmission
He E, Lozano Mag, Stringer S, Watanabe K, Sakamoto K, Den Oudsten F, et al
Human molecular genetics 2018;27(11):1879-1891

Pamela Sklar 1959-2017 obituary
Sullivan Pf, O'donovan Mc, Craddock N
NATURE NEUROSCIENCE 2018;21(2):151-

Protein instability, haploinsufficiency, and cortical hyper-excitability underlie STXBP1 encephalopathy
Kovacevic J, Maroteaux G, Schut D, Loos M, Dubey M, Pitsch J, et al
Brain : a journal of neurology 2018;141(5):1350-1374

Psychiatric Genomics: An Update and an Agenda
Psychiatric Genomics Consortium, Sullivan Pf, Agrawal A, Bulik Cm, Andreassen Oa, Børglum Ad, et al
The American journal of psychiatry 2018;175(1):15-27

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
Schizophrenia Working Group Of The Psychiatric Genomics Consortium, Gusev A, Mancuso N, Won H, Kousi M, Finucane Hk, et al
Nature genetics 2018;50(4):538-548

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype
Direk N, Williams S, Smith Ja, Ripke S, Air T, Amare At, et al
Biological psychiatry 2017;82(5):322-329

Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium
Postpartum Depression: Action Towards Causes And Treatment (pact) Consortium, Putnam Kt, Wilcox M, Robertson-blackmore E, Sharkey K, Bergink V, et al
The lancet. Psychiatry 2017;4(6):477-485

Deep Sequencing of 71 Candidate Genes to Characterize Variation Associated with Alcohol Dependence
Clark Sl, Mcclay Jl, Adkins De, Kumar G, Aberg Ka, Nerella S, et al
Alcoholism, clinical and experimental research 2017;41(4):711-718

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium
Major Depressive Disorder Working Group Of The Psychiatric Genomics Consortium, Peyrot Wj, Van Der Auwera S, Milaneschi Y, Dolan Cv, Madden Paf, et al
Biological psychiatry 2017;():-

Exploration of large, rare copy number variants associated with psychiatric and neurodevelopmental disorders in individuals with anorexia nervosa
Genetic Consortium For Anorexia Nervosa Wellcome Trust Case Control Consortium 3, Yilmaz Z, Szatkiewicz Jp, Crowley Jj, Ancalade N, Brandys Mk, et al
Psychiatric genetics 2017;27(4):152-158

Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues
Liu X, Finucane Hk, Gusev A, Bhatia G, Gazal S, O'connor L, et al
American journal of human genetics 2017;100(4):605-616

Genetic effects influencing risk for major depressive disorder in China and Europe
Bigdeli Tb, Ripke S, Peterson Re, Trzaskowski M, Bacanu Sa, Abdellaoui A, et al
Translational psychiatry 2017;7(3):e1074-

Genetics of Tinnitus: Time to Biobank Phantom Sounds
Cederroth Cr, Kähler Ak, Sullivan Pf, Lopez-escamez Ja
Frontiers in genetics 2017;8():110-

Genomes of the Mouse Collaborative Cross
Srivastava A, Morgan Ap, Najarian Ml, Sarsani Vk, Sigmon Js, Shorter Jr, et al
GENETICS 2017;206(2):537-556

Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia
Li Z, Chen J, Yu H, He L, Xu Y, Zhang D, et al
Nature genetics 2017;49(11):1576-1583

Genome-wide association analysis identifies common variants influencing infant brain volumes
Enigma Consortium, Xia K, Zhang J, Ahn M, Jha S, Crowley Jj, et al
Translational psychiatry 2017;7(8):e1188-

Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Converge Consortium Cardiogram Consortium Gerad1 Consortium, Power Ra, Tansey Ke, Buttenschøn Hn, Cohen-woods S, Bigdeli T, et al
Biological psychiatry 2017;81(4):325-335

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia
Clozapine-induced Agranulocytosis Consortium, Legge Se, Hamshere Ml, Ripke S, Pardinas Af, Goldstein Ji, et al
Molecular psychiatry 2017;22(10):1502-1508

Genome-wide common and rare variant analysis provides novel insights into clozapine- associated neutropenia (vol 22, pg 1502, 2016)
Clozapine-induced Agranulocytosis, Legge Se, Hamshere Ml, Ripke S, Pardinas Af, Goldstein Ji, et al
MOLECULAR PSYCHIATRY 2017;22(10):1509-

How Good Were Candidate Gene Guesses in Schizophrenia Genetics?
Sullivan Pf
Biological psychiatry 2017;82(10):696-697

HUGIn: Hi-C Unifying Genomic Interrogator
Martin Js, Xu Z, Reiner Ap, Mohlke Kl, Sullivan P, Ren B, et al
Bioinformatics (Oxford, England) 2017;33(23):3793-3795

Implication of LRRC4C and DPP6 in neurodevelopmental disorders
Maussion G, Cruceanu C, Rosenfeld Ja, Bell Sc, Jollant F, Szatkiewicz J, et al
American journal of medical genetics. Part A 2017;173(2):395-406

Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders
Nguyen Ht, Bryois J, Kim A, Dobbyn A, Huckins Lm, Munoz-manchado Ab, et al
Genome medicine 2017;9(1):114-

Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia
Leonenko G, Richards Al, Walters Jt, Pocklington A, Chambert K, Al Eissa Mm, et al
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2017;174(7):724-731

National-scale precision medicine for psychiatric disorders in Sweden
Bergen Se, Sullivan Pf
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2017;():-

Schizophrenia and the dynamic genome
Sullivan Pf
Genome medicine 2017;9(1):22-

Sequencing and de novo assembly of 150 genomes from Denmark as a population reference
Maretty L, Jensen Jm, Petersen B, Sibbesen Ja, Liu S, Villesen P, et al
Nature 2017;548(7665):87-91

Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa
Eating Disorders Working Group Of The Psychiatric Genomics Consortium, Duncan L, Yilmaz Z, Gaspar H, Walters R, Goldstein J, et al
The American journal of psychiatry 2017;174(9):850-858

The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability
Interval Study, Uk10k Consortium, Singh T, Walters Jtr, Johnstone M, Curtis D, et al
Nature genetics 2017;49(8):1167-1173

The impact of education, country, race and ethnicity on the self-report of postpartum depression using the Edinburgh Postnatal Depression Scale
Di Florio A, Putnam K, Altemus M, Apter G, Bergink V, Bilszta J, et al
Psychological medicine 2017;47(5):787-799

A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder
Sellgren Cm, Kegel Me, Bergen Se, Ekman Cj, Olsson S, Larsson M, et al
Molecular psychiatry 2016;21(10):1342-50

A hidden Markov random field-based Bayesian method for the detection of long-range chromosomal interactions in Hi-C data
Xu Z, Zhang G, Jin F, Chen M, Furey Ts, Sullivan Pf, et al
Bioinformatics (Oxford, England) 2016;32(5):650-6

Analysis of protein-coding genetic variation in 60,706 humans
Exome Aggregation Consortium, Lek M, Karczewski Kj, Minikel Ev, Samocha Ke, Banks E, et al
Nature 2016;536(7616):285-91

CNS-restricted Transduction and CRISPR/Cas9-mediated Gene Deletion with an Engineered AAV Vector
Murlidharan G, Sakamoto K, Rao L, Corriher T, Wang D, Gao Gp, et al
MOLECULAR THERAPY-NUCLEIC ACIDS 2016;:e338-

Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes
Schizophrenia Working Group Of The Psychiatric Genomics Consortium, Pers Th, Timshel P, Ripke S, Lent S, Sullivan Pf, et al
Human molecular genetics 2016;25(6):1247-54

Deep Sequencing of Three Loci Implicated in Large-Scale Genome-Wide Association Study Smoking Meta-Analyses
Clark Sl, Mcclay Jl, Adkins De, Aberg Ka, Kumar G, Nerella S, et al
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2016;18(5):626-31

Gene expression elucidates functional impact of polygenic risk for schizophrenia
Fromer M, Roussos P, Sieberts Sk, Johnson Js, Kavanagh Dh, Perumal Tm, et al
Nature neuroscience 2016;19(11):1442-1453

Gene expression in major depressive disorder
Jansen R, Penninx Bw, Madar V, Xia K, Milaneschi Y, Hottenga Jj, et al
Molecular psychiatry 2016;21(3):339-47

Gene expression in major depressive disorder
Jansen R, Penninx Bw, Madar V, Xia K, Milaneschi Y, Hottenga Jj, et al
Molecular psychiatry 2016;21(3):444-

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept
Enigma Consortium, Schizophrenia Working Group Of The Psychiatric Genomics Consortium, Franke B, Stein Jl, Ripke S, Anttila V, et al
Nature neuroscience 2016;19(3):420-431

Heritability of Perinatal Depression and Genetic Overlap With Nonperinatal Depression
Viktorin A, Meltzer-brody S, Kuja-halkola R, Sullivan Pf, Landén M, Lichtenstein P, et al
The American journal of psychiatry 2016;173(2):158-65

Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia
Genovese G, Fromer M, Stahl Ea, Ruderfer Dm, Chambert K, Landén M, et al
Nature neuroscience 2016;19(11):1433-1441

Integrative approaches for large-scale transcriptome-wide association studies
Gusev A, Ko A, Shi H, Bhatia G, Chung W, Penninx Bw, et al
Nature genetics 2016;48(3):245-52

Modeling psychiatric disorders: from genomic findings to cellular phenotypes
Falk A, Heine Vm, Harwood Aj, Sullivan Pf, Peitz M, Brüstle O, et al
Molecular psychiatry 2016;21(9):1321-

Modeling psychiatric disorders: from genomic findings to cellular phenotypes
Falk A, Heine Vm, Harwood Aj, Sullivan Pf, Peitz M, Brüstle O, et al
Molecular psychiatry 2016;21(9):1167-79

Nationwide Genomic Study in Denmark Reveals Remarkable Population Homogeneity
Athanasiadis G, Cheng Jy, Vilhjálmsson Bj, Jørgensen Fg, Als Td, Le Hellard S, et al
Genetics 2016;204(2):711-722

No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study
Schizophrenia Working Group Of The Psychiatric Genomics Consortium, Johnson Ec, Bjelland Dw, Howrigan Dp, Abdellaoui A, Breen G, et al
PLoS genetics 2016;12(10):e1006343-

One CNV Discordance in NRXN1 Observed Upon Genome-wide Screening in 38 Pairs of Adult Healthy Monozygotic Twins
Magnusson Pk, Lee D, Chen X, Szatkiewicz J, Pramana S, Teo S, et al
Twin research and human genetics : the official journal of the International Society for Twin Studies 2016;19(2):97-103

Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach
Ruderfer Dm, Charney Aw, Readhead B, Kidd Ba, Kähler Ak, Kenny Pj, et al
The lancet. Psychiatry 2016;3(4):350-7

Quantifying prion disease penetrance using large population control cohorts
Exome Aggregation Consortium (exac), Minikel Ev, Vallabh Sm, Lek M, Estrada K, Samocha Ke, et al
Science translational medicine 2016;8(322):322ra9-

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders
Swedish Schizophrenia Study, Uk10 K Consortium, Ddd Study, Interval Study, Singh T, Kurki Mi, et al
Nature neuroscience 2016;19(4):571-7

Translating genome-wide association findings into new therapeutics for psychiatry
Breen G, Li Q, Roth Bl, O'donnell P, Didriksen M, Dolmetsch R, et al
Nature neuroscience 2016;19(11):1392-1396

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population
Ganna A, Genovese G, Howrigan Dp, Byrnes A, Kurki M, Zekavat Sm, et al
Nature neuroscience 2016;19(12):1563-1565

What Next in Schizophrenia Genetics for the Psychiatric Genomics Consortium?
Corvin A, Sullivan Pf
Schizophrenia bulletin 2016;42(3):538-41

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2
Didion Jp, Morgan Ap, Clayshulte Am, Mcmullan Rc, Yadgary L, Petkov Pm, et al
PLoS genetics 2015;11(2):e1004850-

Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance
Crowley Jj, Zhabotynsky V, Sun W, Huang S, Pakatci Ik, Kim Y, et al
Nature genetics 2015;47(4):353-60

A New Method for Detecting Associations with Rare Copy-Number Variants
Swedish Schizophrenia Consortium, Tzeng Jy, Magnusson Pk, Sullivan Pf, Szatkiewicz Jp
PLoS genetics 2015;11(10):e1005403-

CNV Concordance in 1,097 MZ Twin Pairs
Abdellaoui A, Ehli Ea, Hottenga Jj, Weber Z, Mbarek H, Willemsen G, et al
Twin research and human genetics : the official journal of the International Society for Twin Studies 2015;18(1):1-12

Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use
Clark Sl, Aberg Ka, Nerella S, Kumar G, Mcclay Jl, Chen W, et al
Alcoholism, clinical and experimental research 2015;39(8):1396-405

Corrigendum: analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance
Crowley Jj, Zhabotynsky V, Sun W, Huang S, Pakatci Ik, Kim Y, et al
Nature genetics 2015;47(6):690-

Disruption of the microRNA 137 primary transcript results in early embryonic lethality in mice
Crowley Jj, Collins Al, Lee Rj, Nonneman Rj, Farrell Ms, Ancalade N, et al
Biological psychiatry 2015;77(2):e5-7

Educational attainment influences levels of homozygosity through migration and assortative mating
Abdellaoui A, Hottenga Jj, Willemsen G, Bartels M, Van Beijsterveldt T, Ehli Ea, et al
PloS one 2015;10(3):e0118935-

Evaluating historical candidate genes for schizophrenia
Farrell Ms, Werge T, Sklar P, Owen Mj, Ophoff Ra, O'donovan Mc, et al
Molecular psychiatry 2015;20(5):555-62

Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case-control sample of schizophrenia
Schizophrenia Working Group Of The Psychiatric Genomics Consortium (pgc), Ingason A, Giegling I, Hartmann Am, Genius J, Konte B, et al
Translational psychiatry 2015;5():e656-

Fast eQTL Analysis for Twin Studies
Yin Z, Xia K, Chung W, Sullivan Pf, Zou F
Genetic epidemiology 2015;39(5):357-65

Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences
Giniatullina A, Maroteaux G, Geerts Cj, Koopmans B, Loos M, Klaassen R, et al
Neuroscience 2015;300():518-38

Genetics of disease: Associations with depression
Sullivan Pf
Nature 2015;523(7562):539-40

Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood
Adkins De, Clark Sl, Copeland We, Kennedy M, Conway K, Angold A, et al
Twin research and human genetics : the official journal of the International Society for Twin Studies 2015;18(4):335-47

High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction
Swedish Schizophrenia Consortium, Mcclay Jl, Shabalin Aa, Dozmorov Mg, Adkins De, Kumar G, et al
Genome biology 2015;16():291-

IsoDOT Detects Differential RNA-isoform Expression/Usage with respect to a Categorical or Continuous Covariate with High Sensitivity and Specificity
Sun W, Liu Y, Crowley Jj, Chen Th, Zhou H, Chu H, et al
Journal of the American Statistical Association 2015;110(511):975-986

Meta-analysis of the heritability of human traits based on fifty years of twin studies
Polderman Tj, Benyamin B, De Leeuw Ca, Sullivan Pf, Van Bochoven A, Visscher Pm, et al
Nature genetics 2015;47(7):702-9

Multiple SNP Set Analysis for Genome-Wide Association Studies Through Bayesian Latent Variable Selection
Alzheimer's Disease Neuroimaging Initiative, Lu Zh, Zhu H, Knickmeyer Rc, Sullivan Pf, Williams Sn, et al
Genetic epidemiology 2015;39(8):664-77

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
Rheumatoid Arthritis Consortium International Authors, Rheumatoid Arthritis Consortium International Collaborators, Schizophrenia Working Group Of The Psychiatric Genomics Consortium Collaborators, Schizophrenia Working Group Of The Psychiatric Genomics Consortium Authors, Schizophrenia Working Group Of The Psychiatric Genomics Consortium And Rheumatoid Arthritis Consortium International, Lee Sh, et al
International journal of epidemiology 2015;44(5):1706-21

Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis
Agerbo E, Sullivan Pf, Vilhjálmsson Bj, Pedersen Cb, Mors O, Børglum Ad, et al
JAMA psychiatry 2015;72(7):635-41

Refinement of schizophrenia GWAS loci using methylome-wide association data
Kumar G, Clark Sl, Mcclay Jl, Shabalin Aa, Adkins De, Xie L, et al
Human genetics 2015;134(1):77-87

Schizophrenia: Hope on the Horizon
Sullivan Pf
Cerebrum : the Dana forum on brain science 2015;2015():-

The Mouse Universal Genotyping Array: From Substrains to Subspecies
Morgan Ap, Fu Cp, Kao Cy, Welsh Ce, Didion Jp, Yadgary L, et al
G3 (Bethesda, Md.) 2015;6(2):263-79

The PsychENCODE project
Psychencode Consortium, Akbarian S, Liu C, Knowles Ja, Vaccarino Fm, Farnham Pj, et al
Nature neuroscience 2015;18(12):1707-12

A genome-wide association study of anorexia nervosa
Wellcome Trust Case Control Consortium 3, Boraska V, Franklin Cs, Floyd Ja, Thornton Lm, Huckins Lm, et al
Molecular psychiatry 2014;19(10):1085-94

A meta-analysis of gene expression quantitative trait loci in brain
Kim Y, Xia K, Tao R, Giusti-rodriguez P, Vladimirov V, Van Den Oord E, et al
Translational psychiatry 2014;4():e459-

A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects
Mcclay Jl, Aberg Ka, Clark Sl, Nerella S, Kumar G, Xie Ly, et al
Human molecular genetics 2014;23(5):1175-85

An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis
International Schizophrenia Consortium Sgene+ Consortium, Wellcome Trust Case Control Consortium 2, Morris Dw, Pearson Rd, Cormican P, Kenny Em, et al
Human molecular genetics 2014;23(12):3316-26

A novel statistical approach for jointly analyzing RNA-Seq data from F1 reciprocal crosses and inbred lines
Zou F, Sun W, Crowley Jj, Zhabotynsky V, Sullivan Pf, Pardo-manuel De Villena F
Genetics 2014;197(1):389-99

A polygenic burden of rare disruptive mutations in schizophrenia
Purcell Sm, Moran Jl, Fromer M, Ruderfer D, Solovieff N, Roussos P, et al
Nature 2014;506(7487):185-90

Applying polygenic risk scores to postpartum depression
Psychiatric Genomic Consortium Major Depressive Disorder Working Group, Byrne Em, Carrillo-roa T, Penninx Bw, Sallis Hm, Viktorin A, et al
Archives of women's mental health 2014;17(6):519-28

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles
Goldstein Ji, Jarskog Lf, Hilliard C, Alfirevic A, Duncan L, Fourches D, et al
Nature communications 2014;5():4757-

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1
Wellcome Trust Case Control Consortium, Rees E, Walters Jt, Chambert Kd, O'dushlaine C, Szatkiewicz J, et al
Human molecular genetics 2014;23(6):1669-76

Comorbidity of severe psychotic disorders with measures of substance use
Genomic Psychiatry Cohort Consortium, Hartz Sm, Pato Cn, Medeiros H, Cavazos-rehg P, Sobell Jl, et al
JAMA psychiatry 2014;71(3):248-54

Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity
Heck A, Fastenrath M, Ackermann S, Auschra B, Bickel H, Coynel D, et al
Neuron 2014;81(5):1203-1213

Copy number variation in schizophrenia in Sweden
Szatkiewicz Jp, O'dushlaine C, Chen G, Chambert K, Moran Jl, Neale Bm, et al
Molecular psychiatry 2014;19(7):762-73

Effect of polygenic risk scores on depression in childhood trauma
Peyrot Wj, Milaneschi Y, Abdellaoui A, Sullivan Pf, Hottenga Jj, Boomsma Di, et al
The British journal of psychiatry : the journal of mental science 2014;205(2):113-9

Evidence that duplications of 22q11.2 protect against schizophrenia
Wellcome Trust Case Control Consortium, Rees E, Kirov G, Sanders A, Walters Jt, Chambert Kd, et al
Molecular psychiatry 2014;19(1):37-40

Genetics of adverse reactions to haloperidol in a mouse diallel: a drug-placebo experiment and Bayesian causal analysis
Crowley Jj, Kim Y, Lenarcic Ab, Quackenbush Cr, Barrick Cj, Adkins De, et al
Genetics 2014;196(1):321-47

Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?
Levinson Df, Mostafavi S, Milaneschi Y, Rivera M, Ripke S, Wray Nr, et al
Biological psychiatry 2014;76(7):510-2

Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder
Psychiatric Genomics Consortium: Adhd Subgroup, Hart Ab, Gamazon Er, Engelhardt Be, Sklar P, Kähler Ak, et al
Proceedings of the National Academy of Sciences of the United States of America 2014;111(16):5968-73

Heritability and genomics of gene expression in peripheral blood
Wright Fa, Sullivan Pf, Brooks Ai, Zou F, Sun W, Xia K, et al
Nature genetics 2014;46(5):430-7

Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults
Aberg Ka, Mcclay Jl, Nerella S, Clark S, Kumar G, Chen W, et al
JAMA psychiatry 2014;71(3):255-64

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
Swe-scz Consortium, Schizophrenia Working Group Of The Psychiatric Genomics Consortium, Swe-scz Consortium, Schizophrenia Working Group Of The Psychiatric Genomics Consortium, Gusev A, Lee Sh, et al
American journal of human genetics 2014;95(5):535-52

Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia
Molecular Genetics Of Schizophrenia Consortium, Mulle Jg, Pulver Ae, Mcgrath Ja, Wolyniec Ps, Dodd Af, et al
Biological psychiatry 2014;75(5):371-7

Sex differences in the human peripheral blood transcriptome
Jansen R, Batista S, Brooks Ai, Tischfield Ja, Willemsen G, Van Grootheest G, et al
BMC genomics 2014;15():33-

Specific glial functions contribute to schizophrenia susceptibility
Goudriaan A, De Leeuw C, Ripke S, Hultman Cm, Sklar P, Sullivan Pf, et al
Schizophrenia bulletin 2014;40(4):925-35

A common biological basis of obesity and nicotine addiction
Engage Consortium, Tag Consortium, Oxford-gsk Consortium, Thorgeirsson Te, Gudbjartsson Df, Sulem P, et al
Translational psychiatry 2013;3():e308-

A comprehensive family-based replication study of schizophrenia genes
Aberg Ka, Liu Y, Bukszár J, Mcclay Jl, Khachane An, Andreassen Oa, et al
JAMA psychiatry 2013;70(6):573-81

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs
Schizophrenia Psychiatric Genomics Consortium, Bipolar Disorder Psychiatric Genomics Consortium, Tobacco And Genetics Consortium, Schork Aj, Thompson Wk, Pham P, et al
PLoS genetics 2013;9(4):e1003449-

Association between autozygosity and major depression: stratification due to religious assortment
Abdellaoui A, Hottenga Jj, Xiao X, Scheet P, Ehli Ea, Davies Ge, et al
Behavior genetics 2013;43(6):455-67

Attentional switching forms a genetic link between attention problems and autistic traits in adults
Polderman Tj, Hoekstra Ra, Vinkhuyzen Aa, Sullivan Pf, Van Der Sluis S, Posthuma D
Psychological medicine 2013;43(9):1985-96

Behavioral metabolomics analysis identifies novel neurochemical signatures in methamphetamine sensitization
Adkins De, Mcclay Jl, Vunck Sa, Batman Am, Vann Re, Clark Sl, et al
Genes, brain, and behavior 2013;12(8):780-91

Biclustering with heterogeneous variance
Chen G, Sullivan Pf, Kosorok Mr
Proceedings of the National Academy of Sciences of the United States of America 2013;110(30):12253-8

Comprehensive analysis of copy number variation in monozygotic twins discordant for bipolar disorder or schizophrenia
Bloom Rj, Kähler Ak, Collins Al, Chen G, Cannon Td, Hultman C, et al
Schizophrenia research 2013;146(1-3):289-90

Deep resequencing and association analysis of schizophrenia candidate genes
Crowley Jj, Hilliard Ce, Kim Y, Morgan Mb, Lewis Lr, Muzny Dm, et al
Molecular psychiatry 2013;18(2):138-40

Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders
Stoll G, Pietiläinen Oph, Linder B, Suvisaari J, Brosi C, Hennah W, et al
Nature neuroscience 2013;16(9):1228-1237

Detecting large copy number variants using exome genotyping arrays in a large Swedish schizophrenia sample
Szatkiewicz Jp, Neale Bm, O'dushlaine C, Fromer M, Goldstein Ji, Moran Jl, et al
Molecular psychiatry 2013;18(11):1178-84

Estimation of SNP heritability from dense genotype data
Lee Sh, Yang J, Chen Gb, Ripke S, Stahl Ea, Hultman Cm, et al
American journal of human genetics 2013;93(6):1151-5

Genes, environments, and developmental research: methods for a multi-site study of early substance abuse
Costello Ej, Eaves L, Sullivan P, Kennedy M, Conway K, Adkins De, et al
Twin research and human genetics : the official journal of the International Society for Twin Studies 2013;16(2):505-15

Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia
Mcgrath Lm, Cornelis Mc, Lee Ph, Robinson Eb, Duncan Le, Barnett Jh, et al
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2013;162B(8):779-88

Genome-wide association analysis identifies 13 new risk loci for schizophrenia
Psychosis Endophenotypes International Consortium, Multicenter Genetic Studies Of Schizophrenia Consortium, Wellcome Trust Case Control Consortium 2, Ripke S, O'dushlaine C, Chambert K, et al
Nature genetics 2013;45(10):1150-9

Genome-wide association studies in psychiatry: what have we learned?
Collins Al, Sullivan Pf
The British journal of psychiatry : the journal of mental science 2013;202(1):1-4

Genome-wide association study of patient-rated and clinician-rated global impression of severity during antipsychotic treatment
Clark Sl, Souza Rp, Adkins De, Aberg K, Bukszár J, Mcclay Jl, et al
Pharmacogenetics and genomics 2013;23(2):69-77

Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*D
Adkins De, Souza Rp, Aberg K, Clark Sl, Mcclay Jl, Sullivan Pf, et al
PloS one 2013;8(2):e55239-

Identifying bipolar disorder susceptibility loci in a densely affected pedigree
Collins Al, Kim Y, Szatkiewicz Jp, Bloom Rj, Hilliard Ce, Quackenbush Cr, et al
Molecular psychiatry 2013;18(12):1245-6

Implication of a rare deletion at distal 16p11.2 in schizophrenia
Wellcome Trust Case Control Consortium 2, Molecular Genetics Of Schizophrenia Consortium, Guha S, Rees E, Darvasi A, Ivanov D, et al
JAMA psychiatry 2013;70(3):253-60

Improving detection of copy-number variation by simultaneous bias correction and read-depth segmentation
Szatkiewicz Jp, Wang W, Sullivan Pf, Wang W, Sun W
Nucleic acids research 2013;41(3):1519-32

Increased risk of major depression by childhood abuse is not modified by CNR1 genotype
Pearson Jf, Fergusson Dm, Horwood Lj, Miller Al, Sullivan Pf, Youfang Le, et al
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2013;162B(2):224-6

Initial reactions to tobacco use and risk of future regular use
Zabor Ec, Li Y, Thornton Lm, Shuman Mr, Bulik Cm, Lichtenstein P, et al
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2013;15(2):509-17

MethylPCA: a toolkit to control for confounders in methylome-wide association studies
Chen W, Gao G, Nerella S, Hultman Cm, Magnusson Pk, Sullivan Pf, et al
BMC bioinformatics 2013;14():74-

Mosaic copy number variation in schizophrenia
Ruderfer Dm, Chambert K, Moran J, Talkowski M, Chen Es, Gigek C, et al
European journal of human genetics : EJHG 2013;21(9):1007-11

No effect of genome-wide copy number variation on measures of intelligence in a New Zealand birth cohort
Bagshaw At, Horwood Lj, Liu Y, Fergusson Dm, Sullivan Pf, Kennedy Ma
PloS one 2013;8(1):e55208-

Non-random mating, parent-of-origin, and maternal-fetal incompatibility effects in schizophrenia
Kim Y, Ripke S, Kirov G, Sklar P, Purcell Sm, Owen Mj, et al
Schizophrenia research 2013;143(1):11-7

Population structure, migration, and diversifying selection in the Netherlands
Abdellaoui A, Hottenga Jj, De Knijff P, Nivard Mg, Xiao X, Scheet P, et al
European journal of human genetics : EJHG 2013;21(11):1277-85

Remission, continuation and incidence of eating disorders during early pregnancy: a validation study in a population-based birth cohort
Watson Hj, Von Holle A, Hamer Rm, Knoph Berg C, Torgersen L, Magnus P, et al
Psychological medicine 2013;43(8):1723-34

The EPDS-Lifetime: assessment of lifetime prevalence and risk factors for perinatal depression in a large cohort of depressed women
Meltzer-brody S, Boschloo L, Jones I, Sullivan Pf, Penninx Bw
Archives of women's mental health 2013;16(6):465-73

The genomics of schizophrenia: update and implications
Giusti-rodríguez P, Sullivan Pf
The Journal of clinical investigation 2013;123(11):4557-63

Utilizing twins as controls for non-twin case-materials in genome wide association studies
Ganna A, Ortega-alonso A, Havulinna A, Salomaa V, Kaprio J, Pedersen Nl, et al
PloS one 2013;8(12):e83101-

Antipsychotic-induced vacuous chewing movements and extrapyramidal side effects are highly heritable in mice
Crowley Jj, Adkins De, Pratt Al, Quackenbush Cr, Van Den Oord Ej, Moy Ss, et al
The pharmacogenomics journal 2012;12(2):147-55

Conditions comorbid with chronic fatigue in a population-based sample
Dansie Ej, Furberg H, Afari N, Buchwald D, Edwards K, Goldberg J, et al
Psychosomatics 2012;53(1):44-50

Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth
Fromer M, Moran Jl, Chambert K, Banks E, Bergen Se, Ruderfer Dm, et al
American journal of human genetics 2012;91(4):597-607

Don't give up on GWAS
96 Psychiatric Genetics Investigators, Sullivan P
Molecular psychiatry 2012;17(1):2-3

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs
Molecular Genetics Of Schizophrenia Collaboration (mgs), Schizophrenia Psychiatric Genome-wide Association Study Consortium (pgc-scz), International Schizophrenia Consortium (isc), Lee Sh, Decandia Tr, Ripke S, et al
Nature genetics 2012;44(3):247-50

Exome sequencing and the genetic basis of complex traits
Kiezun A, Garimella K, Do R, Stitziel No, Neale Bm, Mclaren Pj, et al
Nature genetics 2012;44(6):623-30

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies
Pasaniuc B, Rohland N, Mclaren Pj, Garimella K, Zaitlen N, Li H, et al
Nature genetics 2012;44(6):631-5

Familial aggregation of schizophrenia: the moderating effect of age at onset, parental immigration, paternal age and season of birth
Svensson Ac, Lichtenstein P, Sandin S, Öberg S, Sullivan Pf, Hultman Cm
Scandinavian journal of public health 2012;40(1):43-50

Family history of schizophrenia and bipolar disorder as risk factors for autism
Sullivan Pf, Magnusson C, Reichenberg A, Boman M, Dalman C, Davidson M, et al
Archives of general psychiatry 2012;69(11):1099-1103

Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia
International Schizophrenia Consortium, Lips Es, Cornelisse Ln, Toonen Rf, Min Jl, Hultman Cm, et al
Molecular psychiatry 2012;17(10):996-1006

Genetic architectures of psychiatric disorders: the emerging picture and its implications
Sullivan Pf, Daly Mj, O'donovan M
Nature reviews. Genetics 2012;13(8):537-51

Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice
Crowley Jj, Kim Y, Szatkiewicz Jp, Pratt Al, Quackenbush Cr, Adkins De, et al
Mammalian genome : official journal of the International Mammalian Genome Society 2012;23(5-6):322-35

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder
Bergen Se, O'dushlaine Ct, Ripke S, Lee Ph, Ruderfer Dm, Akterin S, et al
Molecular psychiatry 2012;17(9):880-6

Genome-wide association study of antipsychotic-induced QTc interval prolongation
Aberg K, Adkins De, Liu Y, Mcclay Jl, Bukszár J, Jia P, et al
The pharmacogenomics journal 2012;12(2):165-72

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned
Wray Nr, Pergadia Ml, Blackwood Dh, Penninx Bw, Gordon Sd, Nyholt Dr, et al
Molecular psychiatry 2012;17(1):36-48

Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results
International Schizophrenia Consortium, Collins Al, Kim Y, Sklar P, O'donovan Mc, Sullivan Pf
Psychological medicine 2012;42(3):607-16

Lower birth weight indicates higher risk of autistic traits in discordant twin pairs
Losh M, Esserman D, Anckarsäter H, Sullivan Pf, Lichtenstein P
Psychological medicine 2012;42(5):1091-102

MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case--control samples
Swedish Schizophrenia Consortium, Aberg Ka, Mcclay Jl, Nerella S, Xie Ly, Clark Sl, et al
Epigenomics 2012;4(6):605-21

Meta-analysis of genome-wide association studies for personality
De Moor Mh, Costa Pt, Terracciano A, Krueger Rf, De Geus Ej, Toshiko T, et al
Molecular psychiatry 2012;17(3):337-49

Multivariate phenotype association analysis by marker-set kernel machine regression
Maity A, Sullivan Pf, Tzeng Jy
Genetic epidemiology 2012;36(7):686-95

Puzzling over schizophrenia: schizophrenia as a pathway disease
Sullivan Pf
Nature medicine 2012;18(2):210-1

Quantitative analysis of focused a-to-I RNA editing sites by ultra-high-throughput sequencing in psychiatric disorders
Zhu H, Urban Dj, Blashka J, Mcpheeters Mt, Kroeze Wk, Mieczkowski P, et al
PloS one 2012;7(8):e43227-

Runs of homozygosity implicate autozygosity as a schizophrenia risk factor
Schizophrenia Psychiatric Genome-wide Association Study Consortium, Keller Mc, Simonson Ma, Ripke S, Neale Bm, Gejman Pv, et al
PLoS genetics 2012;8(4):e1002656-

seeQTL: a searchable database for human eQTLs
Xia K, Shabalin Aa, Huang S, Madar V, Zhou Yh, Wang W, et al
Bioinformatics (Oxford, England) 2012;28(3):451-2

SNP-based analysis of neuroactive ligand-receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response: data from the CATIE study
Adkins De, Khachane An, Mcclay Jl, Aberg K, Bukszár J, Sullivan Pf, et al
Schizophrenia research 2012;135(1-3):200-1

The authorship network of genome-wide association studies
Bulik-sullivan Bk, Sullivan Pf
Nature genetics 2012;44(2):113-

Transcriptome atlases of mouse brain reveals differential expression across brain regions and genetic backgrounds
Sun W, Lee S, Zhabotynsky V, Zou F, Wright Fa, Crowley Jj, et al
G3 (Bethesda, Md.) 2012;2(2):203-11

zCall: a rare variant caller for array-based genotyping: genetics and population analysis
Arra Autism Sequencing Consortium, Swedish Schizophrenia Consortium, Goldstein Ji, Crenshaw A, Carey J, Grant Gb, et al
Bioinformatics (Oxford, England) 2012;28(19):2543-5

Advancing drug discovery for schizophrenia
Marder Sr, Roth B, Sullivan Pf, Scolnick Em, Nestler Ej, Geyer Ma, et al
Annals of the New York Academy of Sciences 2011;1236():30-43

An unbiased metagenomic search for infectious agents using monozygotic twins discordant for chronic fatigue
Sullivan Pf, Allander T, Lysholm F, Goh S, Persson B, Jacks A, et al
BMC microbiology 2011;11():2-

Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder
Molecular Genetics Of Schizophrenia Collaboration (mgs) International Schizophrenia Consortium (isc) Sgene-plus Group, Williams Hj, Norton N, Dwyer S, Moskvina V, Nikolov I, et al
Molecular psychiatry 2011;16(4):429-41

Genetic risk profiles for depression and anxiety in adult and elderly cohorts
Demirkan A, Penninx Bw, Hek K, Wray Nr, Amin N, Aulchenko Ys, et al
Molecular psychiatry 2011;16(7):773-83

Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics
Mcclay Jl, Adkins De, Aberg K, Stroup S, Perkins Do, Vladimirov Vi, et al
Molecular psychiatry 2011;16(1):76-85

Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs
Adkins De, Aberg K, Mcclay Jl, Bukszár J, Zhao Z, Jia P, et al
Molecular psychiatry 2011;16(3):321-32

Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia
Mcclay Jl, Adkins De, Aberg K, Bukszár J, Khachane An, Keefe Rs, et al
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011;36(3):616-26

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
International Schizophrenia Consortium, Group Investigators, Chen X, Lee G, Maher Bs, Fanous Ah, et al
Molecular psychiatry 2011;16(11):1117-29

LifeGene--a large prospective population-based study of global relevance
Almqvist C, Adami Ho, Franks Pw, Groop L, Ingelsson E, Kere J, et al
European journal of epidemiology 2011;26(1):67-77

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder
Wellcome Trust Case-control Consortium, Liu Y, Blackwood Dh, Caesar S, De Geus Ej, Farmer A, et al
Molecular psychiatry 2011;16(1):2-4

Modifiers and subtype-specific analyses in whole-genome association studies: a likelihood framework
Lee Ph, Bergen Se, Perlis Rh, Sullivan Pf, Sklar P, Smoller Jw, et al
Human heredity 2011;72(1):10-20

Poor replication of candidate genes for major depressive disorder using genome-wide association data
Bosker Fj, Hartman Ca, Nolte Im, Prins Bp, Terpstra P, Posthuma D, et al
Molecular psychiatry 2011;16(5):516-32

Replication of association of 3p21.1 with susceptibility to bipolar disorder but not major depression
Breen G, Lewis Cm, Vassos E, Pergadia Ml, Blackwood Dh, Boomsma Di, et al
Nature genetics 2011;43(1):3-5

Schizophrenia genetics: where next?
Kim Y, Zerwas S, Trace Se, Sullivan Pf
Schizophrenia bulletin 2011;37(3):456-63

Studying gene and gene-environment effects of uncommon and common variants on continuous traits: a marker-set approach using gene-trait similarity regression
Tzeng Jy, Zhang D, Pongpanich M, Smith C, Mccarthy Mi, Sale Mm, et al
American journal of human genetics 2011;89(2):277-88

The genetic structure of the Swedish population
Humphreys K, Grankvist A, Leu M, Hall P, Liu J, Ripatti S, et al
PloS one 2011;6(8):e22547-

Using animal models to disentangle the role of genetic, epigenetic, and environmental influences on behavioral outcomes associated with maternal anxiety and depression
Tarantino Lm, Sullivan Pf, Meltzer-brody S
Frontiers in psychiatry 2011;2():44-

A candidate gene study of Tardive dyskinesia in the CATIE schizophrenia trial
Tsai Ht, Caroff Sn, Miller Dd, Mcevoy J, Lieberman Ja, North Ke, et al
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(1):336-40

A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality
Verweij Kj, Zietsch Bp, Medland Se, Gordon Sd, Benyamin B, Nyholt Dr, et al
Biological psychology 2010;85(2):306-17

A quality control algorithm for filtering SNPs in genome-wide association studies
Pongpanich M, Sullivan Pf, Tzeng Jy
Bioinformatics (Oxford, England) 2010;26(14):1731-7

Association study of 182 candidate genes in anorexia nervosa
Pinheiro Ap, Bulik Cm, Thornton Lm, Sullivan Pf, Root Tl, Bloss Cs, et al
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(5):1070-80

Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression
Huang J, Perlis Rh, Lee Ph, Rush Aj, Fava M, Sachs Gs, et al
The American journal of psychiatry 2010;167(10):1254-63

Genetic differences between five European populations
International Schizophrenia Consortium, Moskvina V, Smith M, Ivanov D, Blackwood D, Stclair D, et al
Human heredity 2010;70(2):141-9

Genome-wide association studies: a primer
Corvin A, Craddock N, Sullivan Pf
Psychological medicine 2010;40(7):1063-77

Genomewide association study of movement-related adverse antipsychotic effects
Aberg K, Adkins De, Bukszár J, Webb Bt, Caroff Sn, Miller Dd, et al
Biological psychiatry 2010;67(3):279-82

Genome-wide association study of suicide attempts in mood disorder patients
Wellcome Trust Case Control Consortium Bipolar Disorder Group, Perlis Rh, Huang J, Purcell S, Fava M, Rush Aj, et al
The American journal of psychiatry 2010;167(12):1499-507

Haplotype-based pharmacogenetic analysis for longitudinal quantitative traits in the presence of dropout
Tzeng Jy, Lu W, Farmen Mw, Liu Y, Sullivan Pf
Journal of biopharmaceutical statistics 2010;20(2):334-50

Latent class analysis of functional somatic symptoms in a population-based sample of twins
Kato K, Sullivan Pf, Pedersen Nl
Journal of psychosomatic research 2010;68(5):447-53

No association of the serotonin transporter polymorphisms 5-HTTLPR and RS25531 with schizophrenia or neurocognition
Konneker Ti, Crowley Jj, Quackenbush Cr, Keefe Rs, Perkins Do, Stroup Ts, et al
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(5):1115-7

Prevalence of incompletely penetrant Huntington's disease alleles among individuals with major depressive disorder
Perlis Rh, Smoller Jw, Mysore J, Sun M, Gillis T, Purcell S, et al
The American journal of psychiatry 2010;167(5):574-9

Response to Mitchell and Porteus
Sullivan Pf, Gejman Pv
Molecular psychiatry 2010;15(5):450-2

The psychiatric GWAS consortium: big science comes to psychiatry
Sullivan Pf
Neuron 2010;68(2):182-6

The public health utility of genome-wide association study results for smoking behavior
Furberg H, Ostroff J, Lerman C, Sullivan Pf
Genome medicine 2010;2(4):26-

A population-based twin study of functional somatic syndromes
Kato K, Sullivan Pf, Evengård B, Pedersen Nl
Psychological medicine 2009;39(3):497-505

Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence
Kuo Ph, Kalsi G, Prescott Ca, Hodgkinson Ca, Goldman D, Alexander J, et al
Drug and alcohol dependence 2009;101(1-2):80-7

A systematic method for estimating individual responses to treatment with antipsychotics in CATIE
Van Den Oord Ej, Adkins De, Mcclay J, Lieberman J, Sullivan Pf
Schizophrenia research 2009;107(1):13-21

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study
Lichtenstein P, Yip Bh, Björk C, Pawitan Y, Cannon Td, Sullivan Pf, et al
Lancet (London, England) 2009;373(9659):234-9

Gene expression in peripheral blood leukocytes in monozygotic twins discordant for chronic fatigue: no evidence of a biomarker
Byrnes A, Jacks A, Dahlman-wright K, Evengard B, Wright Fa, Pedersen Nl, et al
PloS one 2009;4(6):e5805-

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo
Sullivan Pf, De Geus Ej, Willemsen G, James Mr, Smit Jh, Zandbelt T, et al
Molecular psychiatry 2009;14(4):359-75

Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children
Hancock Db, Romieu I, Shi M, Sienra-monge Jj, Wu H, Chiu Gy, et al
PLoS genetics 2009;5(8):e1000623-

Genome-wide association study of alcohol dependence
Treutlein J, Cichon S, Ridinger M, Wodarz N, Soyka M, Zill P, et al
Archives of general psychiatry 2009;66(7):773-84

Genome-wide association study of exercise behavior in Dutch and American adults
De Moor Mh, Liu Yj, Boomsma Di, Li J, Hamilton Jj, Hottenga Jj, et al
Medicine and science in sports and exercise 2009;41(10):1887-95

Genome-wide association study of smoking initiation and current smoking
Vink Jm, Smit Ab, De Geus Ej, Sullivan P, Willemsen G, Hottenga Jj, et al
American journal of human genetics 2009;84(3):367-79

Global similarity with local differences in linkage disequilibrium between the Dutch and HapMap-CEU populations
Pardo L, Bochdanovits Z, De Geus E, Hottenga Jj, Sullivan P, Posthuma D, et al
European journal of human genetics : EJHG 2009;17(6):802-10

Meta-analysis of genome-wide association studies with overlapping subjects
Lin Dy, Sullivan Pf
American journal of human genetics 2009;85(6):862-72

Microduplications of 16p11.2 are associated with schizophrenia
Wellcome Trust Case Control Consortium, Mccarthy Se, Makarov V, Kirov G, Addington Am, Mcclellan J, et al
Nature genetics 2009;41(11):1223-7

Pharmacogenomic genome-wide association studies: lessons learned thus far
Crowley Jj, Sullivan Pf, Mcleod Hl
Pharmacogenomics 2009;10(2):161-3

Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression
Middeldorp Cm, Sullivan Pf, Wray Nr, Hottenga Jj, De Geus Ej, Van Den Berg M, et al
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(3):352-8

An empirical study of the typology of bulimic symptoms in young Portuguese women
Pinheiro Ap, Bulik Cm, Sullivan Pf, Machado Pp
The International journal of eating disorders 2008;41(3):251-8

A searchable database of genetic evidence for psychiatric disorders
Konneker T, Barnes T, Furberg H, Losh M, Bulik Cm, Sullivan Pf
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(6):671-5

Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample
Kuo Ph, Kalsi G, Prescott Ca, Hodgkinson Ca, Goldman D, Van Den Oord Ej, et al
Alcoholism, clinical and experimental research 2008;32(5):785-95

Association of RGS2 and RGS5 variants with schizophrenia symptom severity
Campbell Db, Lange La, Skelly T, Lieberman J, Levitt P, Sullivan Pf
Schizophrenia research 2008;101(1-3):67-75

Comment on a simple and improved correction for population stratification
Lee S, Sullivan Pf, Zou F, Wright Fa
American journal of human genetics 2008;82(2):524-6

Current developments in the genetics of autism: from phenome to genome
Losh M, Sullivan Pf, Trembath D, Piven J
Journal of neuropathology and experimental neurology 2008;67(9):829-37

Ethnic stratification of the association of RGS4 variants with antipsychotic treatment response in schizophrenia
Campbell Db, Ebert Pj, Skelly T, Stroup Ts, Lieberman J, Levitt P, et al
Biological psychiatry 2008;63(1):32-41

Genetic determinants of variable metabolism have little impact on the clinical use of leading antipsychotics in the CATIE study
Grossman I, Sullivan Pf, Walley N, Liu Y, Dawson Jr, Gumbs C, et al
Genetics in medicine : official journal of the American College of Medical Genetics 2008;10(10):720-9

Genetic variation in Transaldolase 1 and risk of squamous cell carcinoma of the head and neck
Basta Pv, Bensen Jt, Tse Ck, Perou Cm, Sullivan Pf, Olshan Af
Cancer detection and prevention 2008;32(3):200-8

Genomewide association for schizophrenia in the CATIE study: results of stage 1
Sullivan Pf, Lin D, Tzeng Jy, Van Den Oord E, Perkins D, Stroup Ts, et al
Molecular psychiatry 2008;13(6):570-84

Genome-wide association of major depression: description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects
Boomsma Di, Willemsen G, Sullivan Pf, Heutink P, Meijer P, Sondervan D, et al
European journal of human genetics : EJHG 2008;16(3):335-42

Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands
Wray Nr, Middeldorp Cm, Birley Aj, Gordon Sd, Sullivan Pf, Visscher Pm, et al
Archives of general psychiatry 2008;65(6):649-58

Genomewide linkage survey of nicotine dependence phenotypes
Sullivan Pf, Kuo Ph, Webb Bt, Neale Mc, Vittum J, Furberg H, et al
Drug and alcohol dependence 2008;93(3):210-6

Linkage on chromosome 14 in a genome-wide linkage study of a broad anxiety phenotype
Middeldorp Cm, Hottenga Jj, Slagboom Pe, Sullivan Pf, De Geus Ej, Posthuma D, et al
Molecular psychiatry 2008;13(1):84-9

Model-based gene selection shows engrailed 1 is associated with antipsychotic response
Webb Bt, Sullivan Pf, Skelly T, Van Den Oord Ej
Pharmacogenetics and genomics 2008;18(9):751-9

Schizophrenia genetics: the search for a hard lead
Sullivan Pf
Current opinion in psychiatry 2008;21(2):157-60

Snus use and other correlates of smoking cessation in the Swedish Twin Registry
Furberg H, Lichtenstein P, Pedersen Nl, Bulik Cm, Lerman C, Sullivan Pf
Psychological medicine 2008;38(9):1299-308

The dice are rolling for schizophrenia genetics
Sullivan Pf
Psychological medicine 2008;38(12):1693-6

The neuregulin 1 promoter polymorphism rs6994992 is not associated with chronic schizophrenia or neurocognition
Crowley Jj, Keefe Rs, Perkins Do, Stroup Ts, Lieberman Ja, Sullivan Pf
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(7):1298-300

The STAGE cohort: a prospective study of tobacco use among Swedish twins
Furberg H, Lichtenstein P, Pedersen Nl, Thornton L, Bulik Cm, Lerman C, et al
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2008;10(12):1727-35

Untapped resources for pharmacogenomic discovery in psychiatry
Crowley Jj, Sullivan Pf, Mcleod Hl
Current opinion in molecular therapeutics 2008;10(3):205-6

Feeling bad in more ways than one: comorbidity patterns of medically unexplained and psychiatric conditions
Schur Ea, Afari N, Furberg H, Olarte M, Goldberg J, Sullivan Pf, et al
Journal of general internal medicine 2007;22(6):818-21

Genetic and phenotypic stability of measures of neuroticism over 22 years
Wray Nr, Birley Aj, Sullivan Pf, Visscher Pm, Martin Ng
Twin research and human genetics : the official journal of the International Society for Twin Studies 2007;10(5):695-702

Irritable bowel syndrome: a co-twin control analysis
Wojczynski Mk, North Ke, Pedersen Nl, Sullivan Pf
The American journal of gastroenterology 2007;102(10):2220-9

New models of collaboration in genome-wide association studies: the Genetic Association Information Network
Bipolar Genome Study, Gain Collaborative Research Group, Genetics Of Kidneys In Diabetes (gokind) Study, Major Depression Stage 1 Genomewide Association In Population-based Samples Study, Collaborative Association Study Of Psoriasis, Molecular Genetics Of Schizophrenia Collaboration, et al
Nature genetics 2007;39(9):1045-51

Patterns of remission, continuation and incidence of broadly defined eating disorders during early pregnancy in the Norwegian Mother and Child Cohort Study (MoBa)
Bulik Cm, Von Holle A, Hamer R, Knoph Berg C, Torgersen L, Magnus P, et al
Psychological medicine 2007;37(8):1109-18

Simulating association studies: a data-based resampling method for candidate regions or whole genome scans
Wright Fa, Huang H, Guan X, Gamiel K, Jeffries C, Barry Wt, et al
Bioinformatics (Oxford, England) 2007;23(19):2581-8

The genetics of anorexia nervosa
Bulik Cm, Slof-op't Landt Mc, Van Furth Ef, Sullivan Pf
Annual review of nutrition 2007;27():263-75

Twin analyses of fatigue
Schur E, Afari N, Goldberg J, Buchwald D, Sullivan Pf
Twin research and human genetics : the official journal of the International Society for Twin Studies 2007;10(5):729-33

A dopamine transporter polymorphism is a risk factor for borderline personality disorder in depressed patients
Joyce Pr, Mchugh Pc, Mckenzie Jm, Sullivan Pf, Mulder Rt, Luty Se, et al
Psychological medicine 2006;36(6):807-13

Genetic, developmental and personality correlates of self-mutilation in depressed patients
Joyce Pr, Mckenzie Jm, Mulder Rt, Luty Se, Sullivan Pf, Miller Al, et al
The Australian and New Zealand journal of psychiatry 2006;40(3):225-9

[Genetics in eating disorders: extending the boundaries of research]
Pinheiro Ap, Sullivan Pf, Bacaltchuck J, Prado-lima Pa, Bulik Cm
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 2006;28(3):218-25

Haplotypes spanning SPEC2, PDZ-GEF2 and ACSL6 genes are associated with schizophrenia
Chen X, Wang X, Hossain S, O'neill Fa, Walsh D, Pless L, et al
Human molecular genetics 2006;15(22):3329-42

Recurrence risks for schizophrenia in a Swedish national cohort
Lichtenstein P, Björk C, Hultman Cm, Scolnick E, Sklar P, Sullivan Pf
Psychological medicine 2006;36(10):1417-25

A genome scan of neuroticism in nicotine dependent smokers
Neale Bm, Sullivan Pf, Kendler Ks
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;132B(1):65-9

Expanding the 'central dogma': the regulatory role of nonprotein coding genes and implications for the genetic liability to schizophrenia
Perkins Do, Jeffries C, Sullivan P
Molecular psychiatry 2005;10(1):69-78

Mania in the Swedish Twin Registry: criterion validity and prevalence
Soldani F, Sullivan Pf, Pedersen Nl
The Australian and New Zealand journal of psychiatry 2005;39(4):235-43

The Irish Affected Sib Pair Study of Alcohol Dependence: study methodology and validation of diagnosis by interview and family history
Prescott Ca, Sullivan Pf, Myers Jm, Patterson Dg, Devitt M, Halberstadt Lj, et al
Alcoholism, clinical and experimental research 2005;29(3):417-29

The use of race variables in genetic studies of complex traits and the goal of reducing health disparities: a transdisciplinary perspective
Shields Ae, Fortun M, Hammonds Em, King Pa, Lerman C, Rapp R, et al
The American psychologist 2005;60(1):77-103

Twin analyses of chronic fatigue in a Swedish national sample
Sullivan Pf, Evengård B, Jacks A, Pedersen Nl
Psychological medicine 2005;35(9):1327-36

A twin study of genetic and environmental influences on tobacco initiation, regular tobacco use and nicotine dependence
Maes Hh, Sullivan Pf, Bulik Cm, Neale Mc, Prescott Ca, Eaves Lj, et al
Psychological medicine 2004;34(7):1251-61

Bipolar II disorder: personality and outcome in two clinical samples
Joyce Pr, Luty Se, Mckenzie Jm, Mulder Rt, Mcintosh Vv, Carter Fa, et al
The Australian and New Zealand journal of psychiatry 2004;38(6):433-8

A framework for controlling false discovery rates and minimizing the amount of genotyping in the search for disease mutations
Van Den Oord Ej, Sullivan Pf
Human heredity 2003;56(4):188-99

False discoveries and models for gene discovery
Van Den Oord Ej, Sullivan Pf
Trends in genetics : TIG 2003;19(10):537-42

Role of exposure with response prevention in cognitive-behavioral therapy for bulimia nervosa: three-year follow-up results
Carter Fa, Mcintosh Vv, Joyce Pr, Sullivan Pf, Bulik Cm
The International journal of eating disorders 2003;33(2):127-35

Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies
Sullivan Pf, Kendler Ks, Neale Mc
Archives of general psychiatry 2003;60(12):1187-92

Temperament, childhood environment and psychopathology as risk factors for avoidant and borderline personality disorders
Joyce Pr, Mckenzie Jm, Luty Se, Mulder Rt, Carter Jd, Sullivan Pf, et al
The Australian and New Zealand journal of psychiatry 2003;37(6):756-64

Melancholia: definitions, risk factors, personality, neuroendocrine markers and differential antidepressant response
Joyce Pr, Mulder Rt, Luty Se, Mckenzie Jm, Sullivan Pf, Abbott Rm, et al
The Australian and New Zealand journal of psychiatry 2002;36(3):376-83

Patterns and predictors of remission, response and recovery in major depression treated with fluoxetine or nortriptyline
Joyce Pr, Mulder Rt, Luty Se, Sullivan Pf, Mckenzie Jm, Abbott Rm, et al
The Australian and New Zealand journal of psychiatry 2002;36(3):384-91

Genetic epidemiology of major depression: review and meta-analysis
Sullivan Pf, Neale Mc, Kendler Ks
The American journal of psychiatry 2000;157(10):1552-62

Rapid and comprehensive determination of cytochrome P450 CYP2D6 poor metabolizer genotypes by multiplex polymerase chain reaction
Roberts R, Joyce P, Kennedy Ma
Human mutation 2000;16(1):77-85

The role of exposure with response prevention in the cognitive-behavioural therapy for bulimia nervosa
Bulik Cm, Sullivan Pf, Carter Fa, Mcintosh Vv, Joyce Pr
Psychological medicine 1998;28(3):611-23

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