Oscar Wiklander
Assistant Professor
E-mail: oscar.wiklander@ki.se
Visiting address: Alfred Nobels Allé 8, 14152 Huddinge
Postal address: H5 Laboratoriemedicin, H5 BCM Wiklander, 171 77 Stockholm
Part of:
- Department of Laboratory Medicine
- Division of Biomolecular and Cellular Medicine (BCM)
About me
- Dr. Wiklander received his PhD in 2017 at KI shortly after receiving his certificate as a medical doctor (leg. läk) following funding as a MD/PhD-student (forskar-AT). He then continued as a resident in oncology (ST-läk) in parallel with conducting his post-doctoral studies until 2023 and 2022, respectively. He divides his time between clinical work and is currently a specialist physician in oncology at Karolinska University Hospital, Theme Cancer, and a team leader with focus on extracellular vesicles in cancer settings, at the department of Laboratory Medicine, KI.
Research
- Research area/interest: Extracellular vesicle-based precision medicine in cancer. Extracellular vesicles (EVs) are a heterogenous group of lipid-bilayer nanovesicles that are secreted by all cells and can be found in all body fluids. These natural nanovesicles range in size from 30-2, 000 nm in diameter and can impact both neighbouring cells or cells at distance. EVs contain lipids, proteins, and nucleic acid species from the source cell, and have the unique ability to convey these macromolecules via an advanced system of intercellular communication. EVs can be seen as a fingerprint of its source cell, reflecting its status and content, and are thus studied as potential biomarkers of various diseases, with particular focus on cancer. The main focus of Dr. Wiklander's research team is to utilize EVs as 1) therapeutic vehicles for advance cancer therapeutics and 2) investigate tumor-derived EVs as potential liquid biopsies for improved diagnostics in cancer settings.
Articles
- Journal article: JOURNAL OF PEPTIDE SCIENCE. 2025;31(10):e70054Lehto T; Isakannu M; Sork H; Lorents A; Bazaz S; Wiklander OPB; Andaloussi SEL; Lehto T
- Journal article: MOLECULAR METABOLISM. 2025;101:102249Vlassakev I; Savva C; Renzi G; Ilamathi HS; Mamand DR; Smith JG; Greco CM; Litwin C; Zhang Q; Velez L; Ma A; Bergo MO; Wiklander OPB; Muñoz-Cánovez P; Mejhert N; Seldin M; Björkegren JLM; Sassone-Corsi P; Koronowski KB; Benitah SA; Petrus P
- Journal article: CANCER LETTERS. 2025;632:217976Ilamathi HS; Rinaldo G; Wiklander OPB
- Article: JOURNAL OF CONTROLLED RELEASE. 2025;382:113665Offens A; Teeuwen L; Akpinar GG; Steiner L; Kooijmans S; Mamand D; Weissinger H; Kall A; Eldh M; Wiklander OPB; El-Andaloussi S; Karlsson MCI; Vader P; Gabrielsson S
- Article: RSC CHEMICAL BIOLOGY. 2025;6(5):761-771Bestas B; Estupinan HY; Wang Q; Kharazi S; He C; K. Mohammad D; Gupta D; Wiklander OPB; Lehto T; Lundin KE; Berglof A; Karlsson MCI; Abendroth F; El Andaloussi S; Gait MJ; Wood MJA; Leumann CJ; Stetsenko DA; Mansson R; Wengel J; Zain R; Smith CIE
- Article: NATURE COMMUNICATIONS. 2025;16(1):4028Liang X; Gupta D; Xie J; Van Wonterghem E; Van Hoecke L; Hean J; Niu Z; Ghaeidamini M; Wiklander OPB; Zheng W; Wiklander RJ; He R; Mamand DR; Bost J; Zhou G; Zhou H; Roudi S; Estupinan HY; Radler J; Zickler AM; Gorgens A; Hou VWQ; Slovak R; Hagey DW; de Jong OG; Uy AG; Zong Y; Mager I; Perez CM; Roberts TC; Carter D; Vader P; Esbjorner EK; de Fougerolles A; Wood MJA; Vandenbroucke RE; Nordin JZ; EL Andaloussi S
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2025;14(2):e70042Singh B; Fredriksson Sundbom M; Muthukrishnan U; Natarajan B; Stransky S; Gorgens A; Nordin JZ; Wiklander OPB; Sandblad L; Sidoli S; El Andaloussi S; Haney M; Gilthorpe JD
- Article: NATURE BIOMEDICAL ENGINEERING. 2024;8(11):1453-1468Wiklander OPB; Mamand DR; Mohammad DK; Zheng W; Jawad Wiklander R; Sych T; Zickler AM; Liang X; Sharma H; Lavado A; Bost J; Roudi S; Corso G; Lennaard AJ; Abedi-Valugerdi M; Maeger I; Alici E; Sezgin E; Nordin JZ; Gupta D; Goergens A; EL Andaloussi S
- Article: ADVANCED SCIENCE. 2024;11(42):e2407619Zickler AM; Liang X; Gupta D; Mamand DR; De Luca M; Corso G; Errichelli L; Hean J; Sen T; Elsharkasy OM; Kamei N; Niu Z; Zhou G; Zhou H; Roudi S; Wiklander OPB; Gorgens A; Nordin JZ; Castilla-Llorente V; EL Andaloussi S
- Article: JOURNAL OF PROTEOME RESEARCH. 2024;23(9):4114-4127Sharma N; Angori S; Sandberg A; Mermelekas G; Lehtio J; Wiklander OPB; Gorgens A; El Andaloussi S; Eriksson H; Pernemalm M
- Article: JOURNAL OF EXTRACELLULAR BIOLOGY. 2024;3(9):1-16Marchan-Álvarez JG; Teeuwen L; Mamand D; Gabrielsson S; Blomgren K; Wiklander O; Newton P
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2024;13(7):e12471Mamand DR; Bazaz S; Mohammad DK; Liang X; Pavlova S; Mim C; Gabrielsson S; Nordin JZ; Wiklander OPB; Abedi-Valugerdi M; EL-Andaloussi S
- Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2024;129:111584Mamand DR; Bazaz S; Mohammad DK; Saher O; Wiklander OPB; Sadeghi B; Hassan M; EL-Andaloussi S; Abedi-Valugerdi M
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2024;13(2):e12404Welsh JA; Goberdhan DCI; O'Driscoll L; Buzas EI; Blenkiron C; Bussolati B; Cai H; Di Vizio D; Driedonks TAP; Erdbrugger U; Falcon-Perez JM; Fu Q-L; Hill AF; Lenassi M; Lim SK; Mahoney MG; Mohanty S; Moller A; Nieuwland R; Ochiya T; Sahoo S; Torrecilhas AC; Zheng L; Zijlstra A; Abuelreich S; Bagabas R; Bergese P; Bridges EM; Brucale M; Burger D; Carney RP; Cocucci E; Colombo F; Crescitelli R; Hanser E; Harris AL; Haughey NJ; Hendrix A; Ivanov AR; Jovanovic-Talisman T; Kruh-Garcia NA; Faustino VK-L; Kyburz D; Lasser C; Lennon KM; Lotvall J; Maddox AL; Martens-Uzunova ES; Mizenko RR; Newman LA; Ridolfi A; Rohde E; Rojalin T; Rowland A; Saftics A; Sandau US; Saugstad JA; Shekari F; Swift S; Ter-Ovanesyan D; Tosar JP; Useckaite Z; Valle F; Varga Z; van der Pol E; van Herwijnen MJC; Wauben MHM; Wehman AM; Williams S; Zendrini A; Zimmerman AJ; Thery C; Witwer KW
- Article: NATURE COMMUNICATIONS. 2023;14(1):4734Zheng W; Raedler J; Sork H; Niu Z; Roudi S; Bost JPP; Goergens A; Zhao Y; Mamand DRR; Liang X; Wiklander OPB; Lehto T; Gupta D; Nordin JZZ; EL Andaloussi S
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(7):e12248Liang X; Niu Z; Galli V; Howe N; Zhao Y; Wiklander OPB; Zheng W; Wiklander RJ; Corso G; Davies C; Hean J; Kyriakopoulou E; Mamand DR; Amin R; Nordin JZ; Gupta D; Andaloussi SEL
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(6):e12238Gorgens A; Corso G; Hagey DW; Wiklander RJ; Gustafsson MO; Felldin U; Lee Y; Bostancioglu RB; Sork H; Liang X; Zheng W; Mohammad DK; van DWSI; Vader P; Zickler AM; Mamand DR; Ma L; Holme MN; Stevens MM; Wiklander OPB; El Andaloussi S
- Article: PHARMACEUTICS. 2021;14(1):38Lennaard AJ; Mamand DR; Wiklander RJ; EL Andaloussi S; Wiklander OPB
- Article: NATURE BIOMEDICAL ENGINEERING. 2021;5(9):1084-1098Gupta D; Wiklander OPB; Görgens A; Conceição M; Corso G; Liang X; Seow Y; Balusu S; Feldin U; Bostancioglu B; Jawad R; Mamand DR; Lee YXF; Hean J; Mäger I; Roberts TC; Gustafsson M; Mohammad DK; Sork H; Backlund A; Lundin P; de Fougerolles A; Smith CIE; Wood MJA; Vandenbroucke RE; Nordin JZ; El-Andaloussi S
- Article: BIOMEDICINES. 2021;9(8):1046Bazaz S; Lehto T; Tops R; Gissberg O; Gupta D; Bestas B; Bost J; Wiklander OPB; Sork H; Zaghloul EM; Mamand DR; Hallbrink M; Sillard R; Saher O; Ezzat K; Smith CIE; El Andaloussi S; Lehto T
- Article: BIOMATERIALS. 2021;266:120435Conceica M; Forcina L; Wiklander OPB; Gupta D; Nordin JZ; Vrellaku B; McClorey G; Mager I; Gorgens A; Lundin P; Musaro A; Wood MJA; Andaloussi SEL; Roberts TC
- Article: ACTA ONCOLOGICA. 2020;59(11):1382-1387Kessler LE; Wiklander O; Hamberg E; Bergh J; Foukakis T; Matikas A
- Article: MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT. 2020;18:880-892Berger E; Colosetti P; Jalabert A; Meugnier E; Wiklander OPB; Jouhet J; Errazurig-Cerda E; Chanon S; Gupta D; Rautureau GJP; Geloen A; El-Andaloussi S; Panthu B; Rieusset J; Rome S
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2020;9(1):1800222Gupta D; Liang X; Pavlova S; Wiklander OPB; Corso G; Zhao Y; Saher O; Bost J; Zickler AM; Piffko A; Maire CL; Ricklefs FL; Gustafsson O; Llorente VC; Gustafsson MO; Bostancioglu RB; Mamand DR; Hagey DW; Goergens A; Nordin JZ; EL Andaloussi S
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2019;8(1):1663043Corso G; Heusermann W; Trojer D; Goergens A; Steib E; Voshol J; Graff A; Genoud C; Lee Y; Hean J; Nordin JZ; Wiklander OPB; El Andaloussi S; Meisner-Kober N
- Article: DIABETES. 2019;68(3):515-526Katayama M; Wiklander OPB; Fritz T; Caidahl K; El-Andaloussi S; Zierath JR; Krook A
- Article: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 2018;132:29-40Saher O; Rocha CSJ; Zaghioul EM; Wiklander OPB; Zamolo S; Heitz M; Ezzat K; Gupta D; Reymond J-L; Zain R; Hollfelder F; Darbre T; Lundin KE; El Andaloussi S; Smith CIE
- Article: SCIENTIFIC REPORTS. 2018;8(1):10813Sork H; Corso G; Krjutskov K; Johansson HJ; Nordin JZ; Wiklander OPB; Lee YXF; Westholm JO; Lehtio J; Wood MJA; Mager I; El Andaloussi S
- Article: FRONTIERS IN IMMUNOLOGY. 2018;9:1326Wiklander OPB; Bostancioglu RB; Welsh JA; Zickler AM; Murke F; Corso G; Felldin U; Hagey DW; Evertsson B; Liang X-M; Gustafsson MO; Mohammad DK; Wiek C; Hanenberg H; Bremer M; Gupta D; Bjornstedt M; Giebel B; Nordin JZ; Jones JC; EL Andaloussi S; Goergens A
- Article: DIABETOLOGIA. 2016;59(5):1049-1058Jalabert A; Vial G; Guay C; Wiklander OPB; Nordin JZ; Aswad H; Forterre A; Meugnier E; Pesenti S; Regazzi R; Danty-Berger E; Ducreux S; Vidal H; El-Andaloussi S; Rieusset J; Rome S
- Article: MOLECULAR THERAPY NUCLEIC ACIDS. 2016;5(3):e290Sork H; Nordin JZ; Turunen JJ; Wiklander OPB; Bestas B; Zaghloul EM; Margus H; Padari K; Duru AD; Corso G; Bost J; Vader P; Pooga M; Smith CIE; Wood MJA; Schiffelers RM; Hallbrink M; Andaloussi SEL
- Article: STEM CELLS TRANSLATIONAL MEDICINE. 2015;4(10):1199-1213Simonson OE; Mougiakakos D; Heldring N; Bassi G; Johansson HJ; Dalen M; Jitschin R; Rodin S; Corbascio M; El Andaloussi S; Wiklander OPB; Nordin JZ; Skog J; Romain C; Koestler T; Hellgren-Johansson L; Schiller P; Joachimsson P-O; Haegglund H; Mattsson M; Lentio J; Faridani OR; Sandberg R; Korsgren O; Krampera M; Weiss DJ; Grinnemo K-H; Le Blanc K
- Article: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. 2015;11(4):879-883Nordin JZ; Lee Y; Vader P; Maeger I; Johansson HJ; Heusermann W; Wiklander OPB; Hallbrink M; Seow Y; Bultema JJ; Gilthorpe J; Davies T; Fairchild PJ; Gabrielsson S; Meisner-Kober NC; Lehtio J; Smith CIE; Wood MJA; Andaloussi SEL
- Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2015;82:186-193Rocha CSJ; Wiklander OPB; Larsson L; Moreno PMD; Parini P; Lundin KE; Smith CIE
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2015;4:26316Wiklander OPB; Nordin JZ; O'Loughlin A; Gustafsson Y; Corso G; Maeger I; Vader P; Lee Y; Sork H; Seow Y; Heldring N; Alvarez-Erviti L; Smith CIE; Le Blanc K; Macchiarini P; Jungebluth P; Wood MJA; EL Andaloussi S
- Article: JOURNAL OF EXTRACELLULAR VESICLES. 2015;4:26883Li J; Lee Y; Johansson HJ; Maeger I; Vader P; Nordin JZ; Wiklander OPB; Lehtio J; Wood MJA; Andaloussi SEL
- Journal article: RESPIRATION. 2015;90(6):481-492Jungebluth P; Holzgraefe B; Lim ML; Duru AD; Lundin V; Heldring N; Wiklander OPB; Nordin JZ; Chrobok M; Roderburg C; Sjoqvist S; Anderstam B; Rodriguez AB; Haag JC; Gustafsson Y; Roddewig KG; Jones P; Wood MJA; Luedde T; Teixeira AI; Hermanson O; Winqvist O; Kalzen H; El Andaloussi S; Alici E; Macchiarini P
- Article: MOVEMENT DISORDERS. 2014;29(12):1476-1485Cooper JM; Wiklander PBO; Nordin JZ; Al-Shawi R; Wood MJ; Vithlani M; Schapira AHV; Simons JP; El-Andaloussi S; Alvarez-Erviti L
- Article: DIABETOLOGIA. 2014;57(10):2155-2164Aswad H; Forterre A; Wiklander OPB; Vial G; Danty-Berger E; Jalabert A; Lamaziere A; Meugnier E; Pesenti S; Ott C; Chikh K; El-Andaloussi S; Vidal H; Lefai E; Rieusset J; Rome S
- Article: MOLECULAR THERAPY NUCLEIC ACIDS. 2014;3(1):e140Stenler S; Wiklander OPB; Badal-Tejedor M; Turunen J; Nordin JZ; Hallengard D; Wahren B; Andaloussi SEL; Rutland MW; Smith CIE; Lundin KE; Blomberg P
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All other publications
- Preprint: BIORXIV. 2025Pavlova S; Mamand DR; Görgens A; Zickler AM; Zheng W; Liang X; Wiklander OPB; Abedi-Valugerdi M; Van Wonterghem E; Xie J; Niu Z; Roudi S; Yan D; Zhou G; Imami K; Wood MPA; Vanderbroucke RE; Andaloussi SE; Gupta D
- Book chapter: CANCER-TARGETED DRUG DELIVERY: METHODS IN PHARMACOLOGY AND TOXICOLOGY. 2025;p. 125-153Ilamathi HS; El Andaloussi S; Wiklander OPB
- Preprint: BIORXIV. 2024Singh B; Sundbom MF; Muthukrishnan U; Natarajan B; Stransky S; Görgens A; Nordin J; Wiklander O; Sandblad L; Sidoli S; Andaloussi SEL; Haney M; Gilthorpe J
- Preprint: RESEARCH SQUARE. 2023Liang X; Gupta D; Xie J; Wonterghem E; Hoecke L; Hean J; Niu Z; Wiklander O; Zheng W; Wiklander R; He R; Mammad D; Bost J; Zhou G; Zhou H; Roudi S; Zickler A; Gorgens A; Hagey D; de Jong O; Uy A; Zong Y; Mager I; Perez C; Roberts T; Vader P; Fougerolles A; Wood M; Vandenbroucke R; Nordin J; El-Andaloussi S
- Preprint: BIORXIV. 2023Zheng W; Rädler J; Sork H; Niu Z; Roudi S; Bost J; Görgens A; Zhao Y; Mamand D; Liang X; Wiklander O; Lehto T; Gupta D; Nordin J; EL Andaloussi S
- Preprint: BIORXIV. 2023Liang X; Gupta D; Xie J; Wonterghem EV; Hoecke LV; Hean J; Niu Z; Wiklander O; Zheng W; Wiklander RJ; He R; Mamand D; Bost J; Zhou G; Zhou H; Roudi S; Zickler AM; Gorgens A; Hagey D; de Jong O; Uy AG; Zong Y; Mager I; Perez CM; Roberts T; Vader P; Fougerolles AD; Wood M; Vandenbroucke R; Nordin J; EL Andaloussi S
- Other: RESPIRATION. 2023;102(5):402-404Jungebluth P; Holzgraefe B; Lim ML; Duru AD; Lundin V; Heldring N; Wiklander OPB; Nordin JZ; Chrobok M; Roderburg C; Sjoqvist S; Anderstam B; Rodriguez AB; C. Haag J; Gustafsson Y; Roddewig KG; Jones P; Wood MJA; Luedde T; Teixeira AI; Hermanson O; Winqvist O; Kalzen H; El Andaloussi S; Alici E; Macchiarini P
- Preprint: BIORXIV. 2023Zickler A; Liang X; Gupta D; Mamand D; Luca MD; Corso G; Errichelli L; Hean J; Sen T; Elsharkasy O; Kamei N; Niu Z; Zhou G; Zhou H; Roudi S; Wiklander O; Görgens A; Nordin J; Castilla-Llorente V; Andaloussi SEL
- Review: EXTRACELLULAR VESICLES AND CIRCULATING NUCLEIC ACIDS. 2023;4(2):170-190Gupta D; Wiklander OPB; Wood MJA; El-Andaloussi S
- Conference publication: ANNALS OF ONCOLOGY. 2022;33(7):S950Sharma N; Mermelekas G; Lehtio J; Wiklander OPB; Gorgens A; Andaloussi S; Pernemalm M; Eriksson H
- Conference publication: MOLECULAR THERAPY. 2021;29(4):220Liang X; Gupta D; Galli V; Zheng W; Davies C; Hean J; Kyriakopoulou E; Yang X; de Andres J; Mamand DR; Amin R; Niu Z; Jawad R; Wiklander O; Zickler A; Gustafsson M; Gorgens A; Nordin JZ; EL Andaloussi S
- Conference publication: MOLECULAR THERAPY. 2021;29(4):332-333Wiklander OPB; Jawad R; Mamand DR; Sharma H; Liang X; Gupta D; Bost J; Zickler AM; Zheng W; Nordin JZ; Gorgens A; Andaloussi SEL
- Preprint: BIORXIV. 2020Gupta D; Wiklander OPB; Görgens A; Conceição M; Corso G; Liang X; Seow Y; Balsu S; Felldin U; Bostancioglu B; Fiona Lee YX; Hean J; Mäger I; Roberts T; Gustafsson M; Mohammad D; Sork H; Bäcklund A; Edvard Smith CI; Wood MJA; Vandenbroucke R; Nordin J; Andaloussi SEL
- Preprint: BIORXIV. 2020Conceição M; Forcina L; Wiklander O; Gupta D; Nordin J; McClorey G; Mäger I; Görgens A; Lundin P; Musarò A; Wood M; Andaloussi SEL; Roberts T
- Review: AUTOIMMUNITY REVIEWS. 2019;18(6):615-620Parodis I; Dani L; Notarnicola A; Martenhed G; Fernstrom P; Matikas A; Wiklander OPB
- Review: SCIENCE TRANSLATIONAL MEDICINE. 2019;11(492):eaav8521Wiklander OPB; Brennan MA; Lotval J; Breakefield XO; EL Andaloussi S
- Conference publication: TRANSPLANTATION. 2016;100(7):S861Jorns C; Watanabe M; Kannisto K; Wiklander O; Zemack H; Strom S; Ericzon B-G; Ellis E
- Corrigendum: STEM CELLS TRANSLATIONAL MEDICINE. 2016;5(6):845Simonson OE; Mougiakakos D; Heldring N; Bassi G; Johansson HJ; Dalen M; Jitschin R; Rodin S; Corbascio M; El Andaloussi S; Wiklander OPB; Nordin JZ; Skog J; Romain C; Koestler T; Hellgren-Johansson L; Schiller P; Joachimsson P-O; Hagglund H; Mattsson M; Lehtio J; Faridani OR; Sandberg R; Korsgren O; Krampera M; Weiss DJ; Grinnemo K-H; Le Blanc K
- Conference publication: HUMAN GENE THERAPY. 2012;23(10):A144-A145Stenler S; Wiklander O; Tejedor MB; Hallengard D; Wahren B; Rutland MW; Smith CIE; Lundin KE; Blomberg P
Grants
- The Swedish Cancer Society1 January 2024 - 31 December 2026In oncology, precision medicine has gained tremendous attention in recent years with the hope to tailor treatments to specific disease driving alterations to improve treatment efficacy and reduce side effects. The need of improved diagnostic tools to identify these specific alterations has also spurred an intense development of various omics to pinpoint relevant biomarkers. Despite intense research, there is still a great need for improved tissue specific targeted drugs and improved diagnostics. The hypothesis of this proposal is that cell secreted exosomes (Exo) could be utilized as therapeutic targetable vectors and as improved cancer biomarkers. The aim is to engineer Exo as tailored targeted therapy and to explore circulating tumor Exo (tExo), acting as a fingerprint of the cancer and its current status, as improved biomarkers for early detection of relapsing cancer. The main objective of this project is to improve cancer care, building on current techniques and therapies, by using Exo as a therapeutic and diagnostic platform.
- Swedish Research Council1 January 2023 - 31 December 2025Despite the immense advances in oncology, not all patients respond to treatment and cancer cells may develop resistant mechanisms, leading to relapse and disseminated incurable disease. There is thus still a desperate need for improved cancer therapies as well as sensitive tools to detect early cancers and relapses. Exosomes (Exo) have the potential to offer a unique platform as a new class of therapeutics as well as a new sensitive diagnostic marker in form of liquid biopsy. Exo are nanometer sized extracellular vesicles that are secreted by all cells and found in all body fluids. Given that their content, including proteins and nucleic acids, is protected by a lipid membrane and reflects that of the source cell, Exo can function as a fingerprint of the patient’s cancer with the ability to reflect the current status of the tumor. In addition, Exo can be engineered to display targeting and therapeutic moieties and can shuttle their cargo over biological barriers. Exo can thus act as natural vectors and offers a unique platform for tailored tumor targeting. This program aims to investigate the potential of using Exo in precision medicine for improved cancer diagnostics and tailored targeted therapies. The first part of this project is to use bioengineered Exo to display antibodies against tumors and to deliver antitumor cargo, whereas the second part involves affinity capture of tumor Exo (tExo) as a liquid biopsy focusing on nucleic acid-based diagnostics.
Employments
- Assistant Professor, Department of Laboratory Medicine, Karolinska Institutet, 2024-2030
Degrees and Education
- Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2018
- University Medical Degree, Karolinska Institutet, 2012