Nicolas Pillon
About me
Docent and team leader for the team inflammation and metabolism, Nicolas Pillon is interested in understanding how the immune system regulates skeletal muscle function and metabolism.
Born in the French Alps, Nicolas moved to Lyon (France) to do his PhD in the laboratory of Dr. Hubert Vidal. In 2011, he joined Prof. Amira Klip's laboratory in Toronto (Canada), where he started working on immunometabolism using /in vitro/ models of inflammation and insulin resistance. Nicolas joined the Karolinska Institutet in 2015 and has been a team leader since 2022.
Research
Imagine your body as a complex system where the immune system is the security team. They need to work in synergy with all other organs for everything to run smoothly, especially when it comes to using energy from food. This balance is key to preventing and managing metabolic diseases, like type 2 diabetes. Our project dives into how these two vital components interact, particularly during exercise or when our body faces challenges like too much sugar. Our goal is to uncover new knowledge that could point us toward better ways to prevent or treat metabolic diseases. This project is about blending detailed scientific research with the bigger picture of improving health. By studying how the immune system and muscles talk to each other, we're hoping to find new strategies to keep everyone healthier.
Teaching
As a dedicated educator in physiology, cellular biology and biomedicine, Nicolas has significantly contributed to both undergraduate and graduate education in Sweden and France. His international experience is highlighted by previous teaching roles at Stockholm University, Université de Lyon, and INSA, emphasizing his commitment to the internationalization of education. He currently leads physiology courses at Karolinska Institutet and KTH Royal Institute of Technology.
Selected publications
- Article: CELL REPORTS MEDICINE. 2024;5(1):101348
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2023;324(4):E289-E298
- Article: SCIENCE ADVANCES. 2022;8(36):eabo3192
- Article: NATURE GENETICS. 2022;54(9):1332-1344
- Article: DIABETES. 2022;71(4):624-636
- Review: CELL. 2021;184(6):1530-1544
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2020;318(3):C615-C626
- Article: NATURE COMMUNICATIONS. 2020;11(1):470
Articles
- Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2024;158:155939
- Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2024;151:155716
- Article: LIFE SCIENCE ALLIANCE. 2023;6(1):e202201598
- Article: INTERNATIONAL JOURNAL OF OBESITY. 2022;46(4):726-738
- Article: MOLECULAR METABOLISM. 2021;53:101290
- Article: SCIENCE ADVANCES. 2021;7(43):eabi9654
- Article: FRONTIERS IN PHYSIOLOGY. 2021;12:619447
- Article: JOURNAL OF PHYSIOLOGY-LONDON. 2020;598(24):5739-5752
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2020;105(6):dgaa165-2041
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2020;318(1):E1-E10
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2019;294(44):16172-16185
- Article: ANALYTICA CHIMICA ACTA. 2018;1037:338-350
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2018;315(5):E995-E1004
- Article: JOURNAL OF LIPID RESEARCH. 2018;59(7):1148-1163
- Article: DIABETOLOGIA. 2018;61(3):688-699
- Article: EXPERIMENTAL CELL RESEARCH. 2017;360(1):47-54
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2016;311(5):E825-E835
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2016;310(2):E160-E170
- Article: NATURE NEUROSCIENCE. 2015;18(8):1081-1083
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2015;290(27):16979-16988
- Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2015;309(1):E35-E44
- Article: DIABETES. 2015;64(3):1011-1024
- Article: DIABETES. 2014;63(11):3815-3826
- Journal article: DIABETES & METABOLISM. 2013;39:a93-a94
- Article: JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2013;24(2):457-466
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2013;24(1):88-99
- Article: CELL COMMUNICATION AND SIGNALING. 2012;10(1):30
- Article: ENDOCRINOLOGY. 2012;153(5):2099-2111
- Journal article: DIABETES & METABOLISM. 2012;38:a29
- Journal article: DIABETES & METABOLISM. 2012;38:a66
- Article: CHEMICAL RESEARCH IN TOXICOLOGY. 2011;24(5):752-762
- Journal article: DIABETES & METABOLISM. 2011;37(1):a15
- Article: INTERNATIONAL JOURNAL OF OBESITY. 2010;34(11):1566-1575
- Article: CHEMICO-BIOLOGICAL INTERACTIONS. 2010;188(1):171-180
- Journal article: DIABETES & METABOLISM. 2010;36:a33
- Journal article: DIABETES & METABOLISM. 2009;35:a46-a47
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All other publications
- Corrigendum: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2023;123(2):247
- Editorial comment: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2023;123(2):243-245
- Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(21):12933
- Review: JOURNAL OF CELLULAR BIOCHEMISTRY. 2022;123(2):202-214
- Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S84-S85
- Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S42-S43
- Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S246
- Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S43
- Preprint: RESEARCH SQUARE. 2021
- Preprint: BIORXIV. 2021
- Preprint: BIORXIV. 2021
- Editorial comment: FRONTIERS IN PHYSIOLOGY. 2021;12:683088
- Preprint: BIORXIV. 2019
- Conference publication: DIABETOLOGIA. 2018;61:S228-S229
- Conference publication: DIABETOLOGIA. 2018;61:S222
- Review: FRONTIERS IN GENETICS. 2018;9:452
- Review: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2017;312(4):E339-E347
- Conference publication: DIABETOLOGIA. 2017;60:S248
- Conference publication: DIABETOLOGIA. 2016;59:S325
- Review: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2013;304(5):E453-E465
- Conference publication: DIABETES. 2013;62:A508
- Book chapter: LIPID PEROXIDATION. 2012;p.
- Conference publication: DIABETES & METABOLISM. 2012;38:A28
- Conference publication: DIABETES & METABOLISM. 2011;37:A68-A69
- Conference publication: DIABETES & METABOLISM. 2011;37:A14
- Published conference paper: JOURNAL OF RENAL NUTRITION. 2011;21(1):72-75
- Conference publication: JOURNAL OF HYPERTENSION. 2008;26:S343
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Grants
- Diabetes Wellness Sverige1 March 2022 - 29 February 2024
- Forska Utan Djurförsök12 December 2021 - 10 September 2025
- EFSD/Novo Nordisk Foundation Future Leaders Awards1 September 2021 - 31 August 2026
- European Commission, Marie Skłodowska-Curie Actions1 May 2016 - 30 April 2018
Employments
- Assistant Senior Lecturer, Department of Physiology and Pharmacology, Karolinska Institutet, 2022-
- Postdoctoral Researcher, Cell Biology, Hospital for Sick Children, 2011-2015
- Lecturer, Biochemistry, Claude Bernard University Lyon 1, 2009-2010
Degrees and Education
- Docent, Karolinska Institutet, 2021
- PhD, Biochemistry, Bioscience, Institut National des Sciences Appliquées de Lyon, 2011
Leadership and responsibility assignments
- Deputy Departmental Director of Education, Physiology and Pharmacology, Karolinska Institute, 2024-
- Course coordinator, Physiology (1BI046), Karolinska Institute, https://education.ki.se/student/physiology-13-credits/1bi046, 2022-
- Research team leader, Inflammation and Metabolism group, Physiology and Pharmacology, Karolinska Institute, https://ki.se/en/research/groups/inflammation-and-metabolism-nicolas-pillons-research-group, 2022-
- Course coordinator, Human Physiology, Karolinska Institute, https://www.kth.se/student/kurser/kurs/CM1010, 2021-
Distinction and awards
- EFSD/Novo Nordisk Foundation Future Leaders Award, European Association for the Study of Diabetes, https://www.europeandiabetesfoundation.org/efsd-novo-nordisk-foundation-future-leaders-award.html, 2021
- Marie Skłodowska-Curie Actions Fellowship, European Commission, 2016