Nicolas Pillon

Nicolas Pillon

Assistant Senior Lecturer | Course coordinator | Docent
Visiting address: Solnavägen 9, Biomedicum C4, 17165 Solna
Postal address: C3 Fysiologi och farmakologi, C3 FyFa IF Inflammation och metabolism, 171 77 Stockholm

About me

  • Docent and team leader for the team inflammation and metabolism, Nicolas Pillon is interested in understanding how the immune system regulates skeletal muscle function and metabolism.

    Born in the French Alps, Nicolas moved to Lyon (France) to do his PhD in the laboratory of Dr. Hubert Vidal. In 2011, he joined Prof. Amira Klip's laboratory in Toronto (Canada), where he started working on immunometabolism using /in vitro/ models of inflammation and insulin resistance. Nicolas joined the Karolinska Institutet in 2015 and has been a team leader since 2022.

Research

  • The field of immunometabolism builds on evidence for the contribution of immunity to the pathogenesis of obesity and type 2 diabetes (T2D). Tissues involved in whole body metabolism become inflamed under metabolic stress and after exercise. However, exercise-associated inflammation and diabetes-associated inflammation trigger different outcomes: the former is needed to confer training adaptations, while the latter contributes to insulin resistance. In these contexts, the study of skeletal muscle immunometabolic responses has been neglected: the association between physical activity and immunometabolic responses and the impact of skeletal muscle inflammation on whole body insulin sensitivity is unknown. Nicolas Pillon's research aims at characterising the immunometabolic responses and identifying novel intervention targets to extinguish or selectively promote components of inflammation with the ultimate aim to improve insulin sensitivity.

Teaching

  • - Course leader. KTH Royal Institute of Technology, Sweden (2021-present). Advanced physiology courses in the Master's Programme in Medical Engineering.
    - Course leader. Karolinska Institutet, Sweden (2022-present). Physiology course in the Bachelor's Programme in Biomedicine.
    - Lecturer. Stockholm University, Sweden (2018-present). Molecular physiology course.
    - Lecturer. Karolinska Institutet, Sweden (2016-present). Undergraduate and doctoral courses.
    - Lecturer. Université de Lyon, France (2009-2010). Lab courses and tutorials in the bachelor's program in biochemistry.
    - Lecturer. Institut National des Sciences Appliquées (INSA), France (2007-2010). Lectures on drug development and lab courses in pharmacology at the bachelor level.

Articles

All other publications

Grants

Employments

  • Assistant Senior Lecturer, Department of Physiology and Pharmacology, Karolinska Institutet, 2022-
  • Postdoctoral Researcher, Cell Biology, Hospital for Sick Children, 2011-2015
  • Lecturer, Biochemistry, Claude Bernard University Lyon 1, 2009-2010

Degrees and Education

  • Docent, Karolinska Institutet, 2021
  • PhD, Biochemistry, Bioscience, Institut National des Sciences Appliquées de Lyon, 2011

Leadership and responsibility assignments

Distinction and awards

News from KI

Events from KI