Neda Rajamand Ekberg

Neda Rajamand Ekberg

Affiliated to Research | Docent

Translational diabetes researcher focusing on precision medicine, diabetes technology, β-cell preservation, and individualized treatment in type 1 and type 2 diabetes.

Visiting address: Karolinska Institutet, BioClinicum J8:20, Visionsgatan 4, 17164 Solna
Postal address: K1 Molekylär medicin och kirurgi, K1 MMK Diabetes och associerade komplikationer, 171 76 Stockholm
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About me

  • Dr. Neda Rajamand Ekberg is Associate Professor (Docent) in Endocrinology at Karolinska Institutet and Senior Consultant at the Centre for Diabetes, Academic Specialist Centre, Stockholm. Her research focuses on translational and precision diabetes research, with particular interest in diabetes technology, metabolic phenotyping, biomarkers, and individualized treatment strategies in type 1 and type 2 diabetes.

    A major focus of her work is the implementation and evaluation of modern diabetes technologies, including continuous glucose monitoring, insulin pumps, automated insulin delivery systems, and digital diabetes care in real-world clinical practice. She is also interested in type 1 diabetes and adult autoimmune diabetes, particularly preservation of β-cell function, prediction of disease progression, and early identification of individuals at high risk of insulin deficiency.

    Her research combines prospective clinical studies, real-world evidence, translational biomarker research, and implementation science, with the aim of rapidly translating research findings into clinical diabetes care. She has authored numerous peer-reviewed publications in international journals within diabetology, metabolism, and translational medicine.

     

Research

  • My research interests focus on translational and precision diabetes research, with the overall aim of improving prevention, diagnosis, individualized treatment, and long-term outcomes in diabetes care. I combine clinical diabetology with real-world and translational research, with strong integration between routine clinical care and research infrastructure.

    A major focus of my research is the implementation and evaluation of modern diabetes technologies, including continuous glucose monitoring, insulin pumps, automated insulin delivery systems, smart insulin pens, and digital diabetes care in real-world clinical practice. My work investigates how these technologies influence glycaemic control, diabetes complications, patient-reported outcomes, and healthcare delivery.

    I also have a strong interest in type 1 diabetes and adult autoimmune diabetes, particularly preservation of residual β-cell function, prediction of disease progression, and early identification of individuals at high risk of insulin deficiency. My research aims to improve risk stratification and monitoring strategies through the use of metabolic markers, C-peptide–based measurements, autoantibodies, and longitudinal clinical follow-up.

    Another important area of interest is precision medicine in type 2 diabetes, including metabolic phenotyping, biomarkers, metabolomics, hormonal regulation, and inflammatory pathways associated with insulin resistance and β-cell dysfunction. In addition, I conduct dietary intervention studies investigating the effects of nutritional strategies on glucose metabolism, insulin sensitivity, inflammation, and remission of type 2 diabetes.

    Methodologically, my research includes prospective clinical studies, real-world evidence studies, translational biomarker research, registry-based studies, and implementation science, with the goal of facilitating rapid translation of research findings into clinical diabetes care.

    Selected publication 

    Peer-reviewed papers in scientific journals

    Tsatsaris G,  Ekberg NR,  Fall T,   Catrina SB. Identification and interpretation of risk factors for Charcot foot. Reply to Milbourn VEL, Bus SA, Game F, van Netten JJ [letter]. DIABETOLOGIA 2025 68;5 1078-1079 View in PubMed

    Karayiannides S,   Widén N,   Tsatsaris G,   Rajamand-Ekberg N,   Catrina SB. SCORE2-Diabetes Predicts the Risk of Heart Failure and Atrial Fibrillation in Individuals With Newly Diagnosed Type 2 Diabetes. Diabetes care 2025 48;9 e104-e106 View in PubMed

    Ekberg NR,  Catrina SB,   Spegel P. A protein-rich meal provides beneficial glycemic and hormonal responses as compared to meals enriched in carbohydrate, fat or fiber, in individuals with or without type-2 diabetes. FRONTIERS IN NUTRITION 2024 11; 1395745-View in PubMed

    Tsatsaris G,  Rajamand Ekberg N,  Fall T,   Catrina SB. Risk factors for Charcot foot development in individuals with diabetes mellitus. Diabetologia 2024 67;12 2702-2710 View in PubMed

    Ekberg NR,  Hartvig NV,   Kaas A,   Møller JB,   Adolfsson P. Smart Pen Exposes Missed Basal Insulin Injections and Reveals the Impact on Glycemic Control in Adults With Type 1 Diabetes. Journal of diabetes science and technology 2024 18;1 66-73. View in PubMed

    Barouti AA,   Björklund A,   Catrina SB,   Brismar K,  Rajamand Ekberg N. Effect of Isocaloric Meals on Postprandial Glycemic and Metabolic Markers in Type 1 Diabetes-A Randomized Crossover Trial. Nutrients 2023 15;14. View in PubMed

    Tsatsaris G,  Rajamand Ekberg N,  Fall T,   Catrina SB. Prevalence of Charcot Foot in Subjects With Diabetes: A Nationwide Cohort Study. Diabetes care 2023 46;12 e217-e218. View in PubMed

    Dos Santos KC,   Olofsson C,   Cunha JPMCM,   Roberts F,   Catrina SB,   Fex M,  Ekberg NR,  Spégel P. The impact of macronutrient composition on metabolic regulation: An Islet-Centric view. Acta physiologica (Oxford, England) 2022 236;4 e13884- View in PubMed

    Olofsson C,   Eriksson M,   Bragfors Helin AC,   Anderstam B,   Orsini N,   Stenvinkel P,  Rajamand Ekberg N. Effects of Acute Fructose Loading on Markers of Inflammation-A Pilot Study. Nutrients 2021 13;9 View in PubMed

     Narayanan S,   Angelstig SE,   Xu C,   Grunler J,   Zhao A,   Zhu W,   Landen NX,   Stahle M,   Zhang JP,   Ivan M,   Maltesen RG,   Botusan IR,  Ekberg NR,  Zheng XW,   Catrina SB. HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism. COMMUNICATIONS BIOLOGY 2020 3;1 768-View in PubMed

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Teaching

  • Dr. Neda Rajamand Ekberg has extensive experience in undergraduate and postgraduate medical education at Karolinska Institutet, particularly within endocrinology and diabetology. Her teaching activities include lectures, seminars, clinical supervision, and research mentorship for medical students, residents, and PhD students. She has a special interest in integrating clinical practice, translational research, and modern diabetes care into medical education, including diabetes technology and precision medicine.

     

Articles

All other publications

Employments

  • Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2025-2028

Degrees and Education

  • Docent, Karolinska Institutet, 2022
  • Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2005
  • University Medical Degree, Karolinska Institutet, 2003

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