Mohsen Moslem

Mohsen Moslem

Affiliated to Research
Visiting address: BioClinicum J5:20, Akademiska stråket 1, Karolinska universitetssjukhu, 17164 Solna
Postal address: K8 Klinisk neurovetenskap, K8 Neuro Svenningsson, 171 77 Stockholm

About me

  • Senior Stem Cell Scientist with 10+ years experience in advanced stem cell
    culture and disease modeling.
    Doctor of Anatomy and Embryology with focus on stem cell and development,
    with more than 10 years of research and teaching experience. I defended my
    PhD in 2012 at Royan Institute and did 3 international postdocs at Hannover
    Medical School (MHH), Hannover, Germany , Ludwig Maximillians University
    (LMU), Munich, Germany and Karolinska Institute, Sweden.


  • My specific field of interest in stem cell biology is disease modeling of
    Parkinson's disease.
    List of Publications:
    Partial Monosomy 21 Mirrors Gene Expression of Trisomy 21 in a
    Patient-Derived Neuroepithelial Stem Cell Model. [1] Schuy J, Eisfeldt J,
    Pettersson M, Shahrokhshahi N, *Moslem M*, Nilsson D, Dahl N, Shahsavani M,
    Falk A, Lindstrand A.Front Genet. 2022 Feb 4
  • 12:803683.
    Crosstalk between astrocytes and microglia results in increased degradation
    of α-synuclein and amyloid-β aggregates. [2] Rostami J, Mothes T,
    Kolahdouzan M, Eriksson O, *Moslem M*, Bergström J, Ingelsson M,
    O'Callaghan P, Healy LM, Falk A, Erlandsson A.J Neuroinflammation. 2021 Jun
  • 18(1):124.
    Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem
    cells. [3] Susanto E, Marin Navarro A, Zhou L, Sundström A, van Bree N,
    Stantic M, *Moslem M*, Tailor J, Rietdijk J, Zubillaga V, Hübner JM,
    Weishaupt H, Wolfsberger J, Alafuzoff I, Nordgren A, Magnaldo T, Siesjö P,
    Johnsen JI, Kool M, Tammimies K, Darabi A, Swartling FJ, Falk A, Wilhelm
    M.Proc Natl Acad Sci U S A. 2020 Aug 18
  • 117(33):20127-20138
    Ataxia in Patients With Bi-Allelic /NFASC/ Mutations and Absence of
    Full-Length NF186. [4] Kvarnung M, Shahsavani M, Taylan F, *Moslem M*,
    Breeuwsma N, Laan L, Schuster J, Jin Z, Nilsson D, Lieden A, Anderlid BM,
    Nordenskjöld M, Syk Lundberg E, Birnir B, Dahl N, Nordgren A, Lindstrand A,
    Falk A.Front Genet. 2019 Sep 24
  • 10:896
    Single cell analysis of autism patient with bi-allelic NRXN1-alpha deletion
    reveals skewed fate choice in neural progenitors and impaired neuronal
    functionality. [5] Lam M, *Moslem M*, Bryois J, Pronk RJ, Uhlin E,
    Ellström ID, Laan L, Olive J, Morse R, Rönnholm H, Louhivuori L, Korol SV,
    Dahl N, Uhlén P, Anderlid BM, Kele M, Sullivan PF, Falk A.Exp Cell Res. 2019
    Oct 1
  • 383(1):111469.
    Stem cell models of schizophrenia, what have we learned and what is the
    potential? [6] *Moslem M*, Olive J, Falk A.Schizophr Res. 2019 Aug
  • 210:3-12
    Kindlin-2 Modulates the Survival, Differentiation, and Migration of Induced
    Pluripotent Cell-Derived Mesenchymal Stromal Cells. [7] *Moslem M*,
    Eggenschwiler R, Wichmann C, Buhmann R, Cantz T, Henschler R.Stem Cells Int.
  • 2017:7316354
    Improved bi-allelic modification of a transcriptionally silent locus in
    patient-derived iPSC by Cas9 nickase. [8] Eggenschwiler R, *Moslem M*,
    Fráguas MS, Galla M, Papp O, Naujock M, Fonfara I, Gensch I, Wähner A,
    Beh-Pajooh A, Mussolino C, Tauscher M, Steinemann D, Wegner F, Petri S,
    Schambach A, Charpentier E, Cathomen T, Cantz T.Sci Rep. 2016 Dec 2
  • 6:38198.
    Mesenchymal Stem/Stromal Cells Derived from Induced Pluripotent Stem Cells
    Support CD34(pos) Hematopoietic Stem Cell Propagation and Suppress
    Inflammatory Reaction. [9] *Moslem M*, Eberle I, Weber I, Henschler R, Cantz
    T.Stem Cells Int. 2015
  • 2015:843058.
    Therapeutic potential of human induced pluripotent stem cell-derived
    mesenchymal stem cells in mice with lethal fulminant hepatic failure.
    [10] *Moslem M*, Valojerdi MR, Pournasr B, Muhammadnejad A, Baharvand H.Cell
    Transplant. 2013
  • 22(10):1785-99.
    Engineered MSCs from Patient-Specific iPS Cells. [11] Eberle I, *Moslem M*,
    Henschler R, Cantz T.Adv Biochem Eng Biotechnol. 2013
  • 130:1-17
    Differentiation and transplantation of human induced pluripotent stem
    cell-derived hepatocyte-like cells. [12] Asgari S, *Moslem M*,
    Bagheri-Lankarani K, Pournasr B, Miryounesi M, Baharvand H.Stem Cell Rev Rep.
    2013 Aug
  • 9(4):493-504.
    Cell-based therapeutics for liver disorders. [13] Vosough M, *Moslem M*,
    Pournasr B, Baharvand H.Br Med Bull. 2011
  • 100:157-72

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