Ming Ho Choi

My ongoing research delves into the roles of mitochondria-endoplasmic reticulum contact sites (MERCS) within adult microglia in Alzheimer's disease (AD). These MERCS harbor distinct protein complexes that oversee crucial physiological functions, and are altered in AD. I aim to elucidate the mechanisms by which MERCS influence these cellular processes and investigate whether manipulating MERCS could mitigate dysfunction in AD.