Mikael Benson

Publications
Public outreach and news

Articles

Journal article: SCIENTIFIC REPORTS. 2024;14(1):12710
An interactive atlas of genomic, proteomic, and metabolomic biomarkers promotes the potential of proteins to predict complex diseases
Smelik M; Zhao Y; Li X; Loscalzo J; Sysoev O; Mahmud F; Mansour Aly D; Benson M
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2024;22(1):444
Transcript and protein signatures derived from shared molecular interactions across cancers are associated with mortality
Zhao Y; Li X; Loscalzo J; Smelik M; Sysoev O; Wang Y; Mahmud AKMF; Mansour Aly D; Benson M
Article: GENOME MEDICINE. 2024;16(1):42
scDrugPrio: a framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases
Schafer S; Smelik M; Sysoev O; Zhao Y; Eklund D; Lilja S; Gustafsson M; Heyn H; Julia A; Kovacs IA; Loscalzo J; Marsal S; Zhang H; Li X; Gawel D; Wang H; Benson M
Article: CELL REPORTS MEDICINE. 2023;4(3):100956
Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases
Lilja S; Li X; Smelik M; Lee EJ; Loscalzo J; Marthanda PB; Hu L; Magnusson M; Sysoev O; Zhang H; Zhao Y; Sjowall C; Gawel D; Wang H; Benson M
Article: EPIGENETICS. 2022;17(9):1040-1055
CD4⁺ T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases
Badam TV; Hellberg S; Mehta RB; Lechner-Scott J; Lea RA; Tost J; Mariette X; Svensson-Arvelund J; Nestor CE; Benson M; Berg G; Jenmalm MC; Gustafsson M; Ernerudh J
Article: GENOME MEDICINE. 2022;14(1):48
A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets
Li X; Lee EJ; Lilja S; Loscalzo J; Schafer S; Smelik M; Strobl MR; Sysoev O; Wang H; Zhang H; Zhao Y; Gawel DR; Bohle B; Benson M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(34):e2110758118
TET2 as a tumor suppressor and therapeutic target in T-cell acute lymphoblastic leukemia
Bensberg M; Rundquist O; Selimovic A; Lagerwall C; Benson M; Gustafsson M; Vogt H; Lentini A; Nestor CE
Article: LAKARTIDNINGEN. 2021;118:20234
[Clinical translation of genomic medicine].
Gawel D; Bojner Horwitz E; Sysoev O; Jacobsson B; Jönsson J-I; Melén E; Ynnerman A; Benson M
Article: RHINOLOGY. 2020;58(4):360-367
Analysis of expression profiling data suggests explanation for difficulties in finding biomarkers for nasal polyps.
Lee EJ; Gawel DR; Lilja S; Li X; Schäfer S; Sysoev O; Zhang H; Benson M
Article: CYTOKINE. 2020;127:154960
Bulk and single cell transcriptomic data indicate that a dichotomy between inflammatory pathways in peripheral blood and arthritic joints complicates biomarker discovery.
Lee EJ; Lilja S; Li X; Schäfer S; Zhang H; Benson M
Article: JOURNAL OF IMMUNOLOGY RESEARCH. 2020;2020:8279619-11
Meta-Analysis of Expression Profiling Data Indicates Need for Combinatorial Biomarkers in Pediatric Ulcerative Colitis.
Li X; Lee EJ; Gawel DR; Lilja S; Schäfer S; Zhang H; Benson M
Article: GENOME MEDICINE. 2019;12(1):4
Digital twins to personalize medicine
Bjornsson B; Borrebaeck C; Elander N; Gasslander T; Gawel DR; Gustafsson M; Jornsten R; Lee EJ; Li X; Lilja S; Martinez-Enguita D; Matussek A; Sandstrom P; Schafer S; Stenmarker M; Sun XF; Sysoev O; Zhang H; Benson M
Article: SCIENTIFIC REPORTS. 2019;9(1):15575
An algorithm-based meta-analysis of genome- and proteome-wide data identifies a combination of potential plasma biomarkers for colorectal cancer
Gawel DR; Lee EJ; Li X; Lilja S; Matussek A; Schafer S; Olsen RS; Stenmarker M; Zhang H; Benson M
Article: GENOME MEDICINE. 2019;11(1):47
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases
Gawel DR; Serra-Musach J; Lilja S; Aagesen J; Arenas A; Asking B; Bengner M; Bjorkander J; Biggs S; Ernerudh J; Hjortswang H; Karlsson J-E; Kopsen M; Lee EJ; Lentini A; Li X; Magnusson M; Martinez-Enguita D; Matussek A; Nestor CE; Schafer S; Seifert O; Sonmez C; Stjernman H; Tjarnberg A; Wu S; Akesson K; Shalek AK; Stenmarker M; Zhang H; Gustafsson M; Benson M

All other publications

Review: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2023;43(3):410-416
Digital Twins for Predictive, Preventive Personalized, and Participatory Treatment of Immune-Mediated Diseases
Benson M
Review: LAKARTIDNINGEN. 2021;118:20213
[Precision medicine in complex diseases].
Melén E; Jacobsson B; Benson M; Orho-Melander M; Halvarson J; Jern C
Corrigendum: CYTOKINE. 2020;133:155087
Corrigendum to "Bulk and single cell transcriptomic data indicate that a dichotomy between inflammatory pathways in peripheral blood and arthritic joints complicates biomarker discovery" [Cytokine 127 (2020) 154960].
Lee EJ; Lilja S; Li X; Schäfer S; Zhang H; Benson M
Corrigendum: GENOME MEDICINE. 2020;12(1):37
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases (vol 11, 47, 2019)
Gawel DR; Serra-Musach J; Lilja S; Aagesen J; Arenas A; Asking B; Bengner M; Bjorkander J; Biggs S; Ernerudh J; Hjortswang H; Karlsson J-E; Kopsen M; Lee EJ; Lentini A; Li X; Magnusson M; Martinez-Enguita D; Matussek A; Nestor CE; Schafer S; Seifert O; Sonmez C; Stjernman H; Tjarnberg A; Wu S; Akesson K; Shalek AK; Stenmarker M; Zhang H; Gustafsson M; Benson M
Editorial comment: GENOME MEDICINE. 2019;11(1):9
Translating genomic medicine to the clinic: challenges and opportunities
Zhang H; Klareskog L; Matussek A; Pfister SM; Benson M

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