Mattias Günther
About me
Anesthesiologist and intensive care physician at Södersjukhuset (Stockholm South General Hospital), and principal investigator in Experimental Traumatology at Karolinska Institutet. My work bridges clinical trauma and intensive care with translational research in defence-related medicine. I serve as Scientific Secretary for the Centre for Trauma Research at Karolinska Institutet.
Research
My research focuses on advancing trauma and defence-related medicine through experimental models that replicate realistic injury scenarios — from blast-induced brain injury to severe hemorrhage. In collaboration with the Swedish Armed Forces and international partners, we aim to translate laboratory findings into practical medical solutions that improve survival and recovery after trauma.
ReBINT (Repeated Blast Induced Neurotrauma Research Initiative) explores how repeated blast exposure affects the brain. Using a unique experimental blast model, we study injury mechanisms, identify biomarkers for early diagnosis, and develop improved protective equipment and treatments to reduce long-term effects of blast-related neurotrauma.
TRIDENT (Trauma Resuscitation, Intervention, and Emergency Damage Control for Preventing Military Avoidable Deaths) targets preventable trauma deaths caused by bleeding and airway obstruction. Through advanced trauma models and neurointensive monitoring, we evaluate novel resuscitation strategies, protective systems, and cold-weather trauma care to enhance survival in both military and civilian contexts.
Articles
- Journal article: EXPERIMENTAL LUNG RESEARCH. 2025;51(1):91-103Kildal VV; Gustavsson J; Guenther M
- Article: EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY. 2025;51(1):301Kildal VV; Dahlberg M; Ek CH; Oldner A; Wikman A; Wahlgren CM; Guenther M
- Journal article: BMJ MILITARY HEALTH. 2025;171(Suppl 1):a30-a31Thors L; Arborelius U; Bucht A; Günther M
- Article: JOURNAL OF SURGICAL RESEARCH. 2025;314:580-588Luckhurst C; Brannstrom A; Gustavsson J; Gunther M
- Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112(Supplement_11):znaf149.011Holtenius F; Günther M; Älgå A
- Article: SCIENTIFIC REPORTS. 2025;15(1):20295Rundgren H; Sjoholm J; Juric S; Janson P; Kolerud J; Wallin R; Skorup P; Lipcsey M; Guenther M
- Article: ANESTHESIA AND ANALGESIA. 2025Karlsson T; Gustavsson J; Wellfelt K; Günther M
- Article: TRANSFUSION. 2025;65(Suppl 1):s68-s79Renberg M; Karlsson T; Gellerfors M; Gustavsson J; Wellfelt K; Gunther M
- Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2025;13(1):31Karlsson T; Gustavsson J; Wellfelt K; Gunther M
- Article: PHYSIOLOGICAL REPORTS. 2024;12(23):e70147Gottschalk F; Gennser M; Gunther M; Eiken O; Elia A
- Article: EXPERIMENTAL PHYSIOLOGY. 2024;109(9):1517-1528Gottschalk F; Gennser M; Guenther M; Eiken O; Elia A
- Article: EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY. 2024;50(4):1879-1889Renberg M; Karlsson T; Dahlquist A; Luckhurst C; Gustavsson J; Arborelius U; Risling M; Gunther M
- Article: WORLD NEUROSURGERY. 2024;182:e493-e505Lilford RD; Hossain I; Dahlberg M; Wahlgren C-M; Bellander B-M; Rostami A; Gunther M; Bartek J; Rostami E
- Article: EUROPEAN JOURNAL OF MEDICAL RESEARCH. 2023;28(1):597Harbut P; Campoccia Jalde F; Dahlberg M; Forsgren A; Andersson E; Lundholm A; Janc J; Lesnik P; Suchanski M; Zatorski P; Trzebicki J; Skalec T; Gunther M
- Article: ANNALS OF BIOMEDICAL ENGINEERING. 2023;51(12):2762-2771Karlsson T; Olsson L-G; Gustavsson J; Arborelius UP; Risling M; Guenther M
- Article: SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE. 2023;31(1):85Renberg M; Dahlberg M; Gellerfors M; Rostami E; Gunther M
- Article: SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE. 2023;31(1):45Renberg M; Dahlberg M; Gellerfors M; Rostami A; Gunther M; Rostami E
- Article: EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY. 2023;49(3):1303-1313Brannstrom A; Hultstrom M; Gustavsson J; Aurfan Z; Gunther M
- Article: TRANSFUSION. 2023;63:S213-S221Karlsson T; Gellerfors M; Gustavsson J; Gunther M
- Article: MILITARY MEDICAL RESEARCH. 2022;9(1):57Karlsson T; Brannstrom A; Gellerfors M; Gustavsson J; Gunther M
- Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2022;10(1):14Skorup P; Fransson A; Gustavsson J; Sjoholm J; Rundgren H; ozenci V; Wong AYW; Karlsson T; Svensen C; Gunther M
- Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2022;66(3):365-374Jonmarker S; Litorell J; Dahlberg M; Stackelberg O; Everhov AH; Soderberg M; Rubenson-Wahlin R; Gunther M; Martensson J; Hollenberg J; Joelsson-Alm E; Cronhjort M
- Article: EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY. 2022;48(1):401-409Dahlquist A; Degerstedt LE; von Oelreich E; Brannstrom A; Gustavsson J; Arborelius UP; Gunther M
- Article: EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY. 2022;48(1):335-344Brannstrom A; Dahlquist A; Gustavsson J; Arborelius UP; Gunther M
- Article: ANNALS OF BIOMEDICAL ENGINEERING. 2022;50(1):78-85Gunther M; Arborelius U; Risling M; Gustavsson J; Sonden A
- Article: FRONTIERS IN NEUROLOGY. 2021;12:730405Guenther M; Dahlberg M; Rostami A; Azadali A; Arborelius UP; Linder F; Rostami E
- Article: PREHOSPITAL AND DISASTER MEDICINE. 2021;36(5):547-552Renberg M; Hertzberg D; Kornhall D; Gunther M; Gellerfors M
- Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2021;65(9):1329-1336Arnason B; Hertzberg D; Kornhall D; Gunther M; Gellerfors M
- Article: EXPERIMENTAL LUNG RESEARCH. 2021;47(7):323-333Arborelius UP; Rocksen D; Gustavsson J; Gunther M
- Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2021;65(3):360-363Gleissman H; Forsgren A; Andersson E; Lindqvist E; Lipka Falck A; Cronhjort M; Dahlberg M; Guenther M
- Article: JOURNAL OF TRAUMA AND ACUTE CARE SURGERY. 2021;90(2):360-368Brannstrom A; von Oelreich E; Degerstedt LE; Dahlquist A; Hanell A; Gustavsson J; Gunther M
- Article: CRITICAL CARE. 2020;24(1):653Jonmarker S; Hollenberg J; Dahlberg M; Stackelberg O; Litorell J; Everhov AH; Jarnbert-Pettersson H; Soderberg M; Grip J; Schandl A; Gunther M; Cronhjort M
- Article: EXPERIMENTAL LUNG RESEARCH. 2020;46(8):271-282Rocksen D; Arborelius UP; Gustavsson J; Guenther M
- Article: EXPERIMENTAL LUNG RESEARCH. 2020;46(5):117-127Guenther M; Sonden A; Gustavsson J; Arborelius UP; Rocksen D
- Article: RESTORATIVE NEUROLOGY AND NEUROSCIENCE. 2020;38(1):23-40Gunther M; Skold MK
- Article: JOURNAL OF TRAUMA AND ACUTE CARE SURGERY. 2019;87(4):849-855Brannstrom A; Dahlquist A; Gustavsson J; Arborelius UP; Guenther M
- Article: FRONTIERS IN NEUROLOGY. 2019;10:811Jadid KD; Davidsson J; Lidin E; Hanell A; Angeria M; Mathiesen T; Risling M; Gunther M
- Article: JOURNAL OF CLINICAL NEUROSCIENCE. 2019;64:227-233Vanden Berg RW; Davidsson J; Lidin E; Angeria M; Risling M; Gunther M
- Article: JOURNAL OF TRAUMA AND ACUTE CARE SURGERY. 2018;85(4):717-724Brannstrom A; Rocksen D; Hartman J; Nyman N; Gustavsson J; Arborelius UP; Gunther M
- Article: ENEURO. 2018;5(2):ENEURO.0335-ENEU17.2018Gunther M; Al Nimer F; Piehl F; Risling M; Mathiesen T
- Article: JOURNAL OF CLINICAL NEUROSCIENCE. 2015;22(9):1477-1483Gunther M; Davidsson J; Plantman S; Norgren S; Mathiesen T; Risling M
- Article: ACTA NEUROCHIRURGICA. 2015;157(4):649-659Gunther M; Plantman S; Davidsson J; Angeria M; Mathiesen T; Risling M
- Article: ACTA NEUROCHIRURGICA. 2014;156(12):2365-2378Gunther M; Plantman S; Gahm C; Sonden A; Risling M; Mathiesen T
- Article: ACTA NEUROCHIRURGICA. 2012;154(4):689-697Guenther M; Al Nimer F; Gahm C; Piehl F; Mathiesen T
- Article: OTOLOGY & NEUROTOLOGY. 2010;31(9):1493-1497Gunther M; Danckwardt-Lilliestrom N; Gudjonsson O; Nyberg G; Kinnefors A; Rask-Andersen H; Ekvall L
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All other publications
- Preprint: MEDRXIV. 2020Jonmarker S; Hollenberg J; Dahlberg M; Stackelberg O; Litorell J; Everhov Å; Järnbert-Pettersson H; Söderberg M; Grip J; Schandl A; Günther M; Cronhjort M
- Letter: JOURNAL OF TRAUMA AND ACUTE CARE SURGERY. 2019;87(3):741Gunther M; Brannstrom A
- Conference publication: JOURNAL OF NEUROTRAUMA. 2016;33(3):A12-A13Skold M; Gunther M
- Conference publication: JOURNAL OF NEUROTRAUMA. 2014;31(5):A18Gunther M; Plantman S; Davidsson J; Angeria M; Mathiesen T; Risling M
- Conference publication: JOURNAL OF NEUROTRAUMA. 2013;30(15):A93-A94Gunther M; Plantman S; Angeria M; Mathiesen T; Risling M
- Conference publication: BRAIN INJURY. 2012;26(4-5):368Gunther M; Al Nimer F; Gahm C; Mathiesen T
Employments
- Principal Researcher, Department of Neuroscience, Karolinska Institutet, 2022-
- Affiliated to Research, Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, 2023-2026
Degrees and Education
- Docent, Karolinska Institutet, 2021
- Degree Of Doctor Of Philosophy, Department of neuroscience, Karolinska Institutet, 2015
Supervision
Supervision to doctoral degree
- Frode Gottschalk, The effect of eccentric exercise on decompression strain, https://openarchive.ki.se/articles/thesis/The_effect_of_eccentric_exercise_on_decompression_strain/27620190?file=50253024, 2024
