Mattias Carlsten
Affiliated to Research | Docent
E-mail: mattias.carlsten@ki.se
Visiting address: ,
Postal address: H5 Laboratoriemedicin, H5 BCM Carlsten, 171 77 Stockholm
About me
- I received my MD degree from Karolinska Institutet 2007 after conducting
studies within the MD/PhD program. Following completion of my medical
intership (Forskar-AT) at the Karolinska University Hospital late fall 2009,
I defended my PhD thesis at Karolinska Institutet early spring 2010
supervised by Prof. Karl-Johan Malmbergs and Prof. Rolf Kiessling. I then
joined the group of Dr. Richard W. Childs at Hematology Branch, NHLBI, NIH
(USA) as a Postdoc 2010. Since 2012 I have been doing my residency/fellowship
in Internal Medicine/Hematology at Center for Hematology, Karolinska
University Hospital, with the exception of a sabatical between 2013-2015 when
I was employed as a Staff Scientist with Dr. Childs at the NIH. From 2016, I
am a Research Group leader at Center for Regenerative Medicine and
Hematology (HERM), Department of Medicine Huddinge, Karolinska Institutet.
2015, SSMF Stora Anslag
2015, Jeanssons Stiftelser Personal Achievement Award
2012, Translational Research Training in Hematology (TRTH) Award
2010, Dean O’Neill Renal Cancer Cell Research Fellowship
2004, MD/PhD program at Karolinska Institutet
2000, Läkarutbildningen med forskningsinriktning (LäFo), Karolinska
Institutet
2007, MD, Karolinska Institutet
2009, Swedish Medical Practioner License, Karolinska University Hospital
2010, PhD, Karolinska Institutet
2010-2012, Postdoctoral Fellow, Hematology Branch, NHLBI, NIH
2013-2015, Staff Scientist, Hematology Branch, NHLBI, NIH
2012-, Resident/Fellow in Internal Medicine/Hematology, Karolinska University
Hospital
2016-, Research Group Leader, HERM, Department of Medicine Huddinge,
Karolinska Institutet
Research
- My research focuses on cancer immunotherapy, with a particular focus on how
NK cells can be used to treat cancer. With my experience in bench science and
clinical medicine, my projects spans from preclinical basic NK cell biology
and tumor immunology studies to translational to early phase clinical trials
on NK cell-based cancer immunotherapy and stem cell transplantation. A big
focus in my lab is currently how genetic engineering of lymphocytes,
including NK cells, can be used to further improve the efficacy of cellular
cancer immunotherapies.
Articles
- Article: CURRENT PROTOCOLS. 2024;4(11):e70040
- Article: MOLECULAR THERAPY: METHODS & CLINICAL DEVELOPMENT. 2024;32(2):101225
- Article: NPJ PRECISION ONCOLOGY. 2024;8(1):108
- Article: LEUKEMIA. 2024;38(3):579-589
- Article: LEUKEMIA. 2023;37(9):1830-1841
- Article: EJNMMI RESEARCH. 2023;13(1):73
- Article: HAEMATOLOGICA. 2022;107(8):1786-1795
- Article: BLOOD ADVANCES. 2022;6(11):3352-3366
- Article: VIRCHOWS ARCHIV. 2022;480(3):655-666
- Article: MOLECULAR IMAGING AND BIOLOGY. 2021;23(6):952-962
- Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(10):e1346
- Article: METHODS IN MOLECULAR BIOLOGY. 2020;2121:213-239
- Article: EXPERIMENTAL HEMATOLOGY & ONCOLOGY. 2019;8:7
- Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2164
- Article: ONCOIMMUNOLOGY. 2019;8(2):e1534664
- Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1262
- Article: CLINICAL CANCER RESEARCH. 2018;24(8):1834-1844
- Article: PLOS ONE. 2018;13(8):e0202651
- Article: CLINICAL CANCER RESEARCH. 2016;22(21):5211-5222
- Article: METHODS IN MOLECULAR BIOLOGY. 2016;1441:231-240
- Article: JOURNAL OF IMMUNOLOGY. 2015;194(9):4518-4527
- Article: MOLECULAR THERAPY. 2014;22(7):1388-1395
- Article: INTERNATIONAL JOURNAL OF CANCER. 2013;133(7):1643-1652
- Article: JOURNAL OF IMMUNOLOGY. 2011;187(7):3546-3554
- Article: LEUKEMIA. 2010;24(9):1607-1616
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2009;390(4):1272-1277
- Article: JOURNAL OF IMMUNOLOGY. 2009;183(8):4921-4930
- Article: JOURNAL OF IMMUNOLOGY. 2008;181(9):6010-6019
- Article: CANCER IMMUNOLOGY, IMMUNOTHERAPY. 2007;56(7):973-984
- Article: CANCER RESEARCH. 2007;67(3):1317-1325
- Article: CANCER RESEARCH. 2006;66(12):6387-6394
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2002;110(10):1515-1523
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(32):30542-30551
- Article: BIOCHEMICAL JOURNAL. 2000;347(Pt 3):661-668
- Show more
All other publications
- Letter: HEMASPHERE. 2023;7(11):e974
- Editorial comment: SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2023;8(1):316
- Conference publication: BRITISH JOURNAL OF HAEMATOLOGY. 2023;201:114-115
- Corrigendum: MOLECULAR IMAGING AND BIOLOGY. 2022;24(3):510
- Review: FRONTIERS IN IMMUNOLOGY. 2020;11:621225
- Review: FRONTIERS IN IMMUNOLOGY. 2019;10:1047
- Review: FRONTIERS IN IMMUNOLOGY. 2019;10:2357
- Review: SEMINARS IN IMMUNOLOGY. 2017;31:20-29
- Corrigendum: BLOOD CANCER JOURNAL. 2015;5(7):e321
- Review: NATURE REVIEWS DRUG DISCOVERY. 2015;14(7):487-498
- Review: FRONTIERS IN IMMUNOLOGY. 2015;6:266
- Letter: HAEMATOLOGICA. 2014;99(6):E81-E83
- Thesis / dissertation: 2010
- Review: INTERNATIONAL JOURNAL OF CANCER. 2009;124(4):757-762
- Published conference paper: CANCER IMMUNOLOGY, IMMUNOTHERAPY. 2008;57(10):1541-1552
Employments
- Affiliated to Research, Department of Laboratory Medicine, Karolinska Institutet, 2024-2027
Degrees and Education
- Docent, Karolinska Institutet, 2022
- Degree Of Doctor Of Philosophy, Department of Medicine, Huddinge, Karolinska Institutet, 2010
- University Medical Degree, Karolinska Institutet, 2007