Mattias Bronge
Affiliated to Research
E-mail: mattias.bronge@ki.se
Visiting address: L8:04, CMM Karolinska Universitetssjukhuset Solna, 17176 Stockholm
Postal address: K8 Klinisk neurovetenskap, K8 Neuro Thomas, 171 77 Stockholm
Part of:
About me
I am a resident doctor in neurology at Karolinska University Hospital and affiliated researcher at
the Department of Clinical Neuroscience, Karolinska Institutet. My research focuses on the
immunological mechanisms driving autoimmune neurological diseases like multiple sclerosis and translating these finding into clinical tools.
Research
My former PhD-project "Identification of novel autoantigens in multiple sclerosis" centered around the pathological autoreactive T cells and their target autoantigens in multiple sclerosis. By using novel T-cell reactivity platform developed during the project, we identified previously unknown autoantigens and characterized the heterogenous autoreactive profiles in persons with MS. Additionally, we demonstrated a mechanistic link between Epstein-Barr virus infection and MS developement via molecular mimicry between the EBV antigen EBNA1 and the autoantigen CRYAB.
The long term aim is to utilize the individual autoreactive profiles to improve diagnostic and prognostic tools, leading to better healthcare for persons with MS.
Articles
- Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2026;123(36)Lutterotti A; Ludersdorfer T; Docampo MJ; Morax M; Hayward-Koennecke H; Oldrati P; Kalaitzaki V; Marti Z; Zaugg A; Bronge M; Thomas OG; Ferreira FM; Moreno CS; Cruciani C; Naghavian R; Castillo JSD; Tillé L; Reindl M; Englezou PC; Stenger R; Jelcic I; Pfender N; Hilty M; Foege M; Guffanti F; Weichselbaumer V; Blanc A; Buch T; Hüllner M; Winklhofer S; Treyer V; Goede JS; Behe M; Broggini M; Scanziani E; Olsson T; Grönlund H; Sormani MP; Kayser M; Sospedra M; Martin R
- Article: CELL. 2026;189(2):585-602.e38Thomas OG; Rykaczewska U; Galesic M; Van Der Burgt RTM; Hallen N; Ferro F; Bronge M; Marti Z; Li Y; Rique AH; Lin J; Krstic A; Gromadzka A; Szonder AL; Sorini C; Reina-Campos M; Sun T; Rodriguez-Kirby LAR; Dumral O; Berglund R; Kakhki MP; Adzemovic MZ; Zeitelhofer M; Akpinar B; Tengvall K; Nilsson OB; Holmgren E; Cucuzza CS; Hogelin KA; Gafvelin G; Fink K; Castelo-Branco G; Needhamsen M; Khademi M; Piehl F; Graslund T; Alfredsson L; Lund H; Uhlen P; Kockum I; Martin R; Jagodic M; Gronlund H; Guerreiro-Cacais AO; Olsson T
- Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1334720Marti Z; Ruder J; Thomas OG; Bronge M; Soto LDLP; Gronlund H; Olsson T; Martin R
- Article: SCIENCE ADVANCES. 2023;9(20):eadg3032Thomas OG; Bronge M; Tengvall K; Akpinar B; Nilsson OB; Holmgren E; Hessa T; Gafvelin G; Khademi M; Alfredsson L; Martin R; Guerreiro-Cacais AO; Groenlund H; Olsson T; Kockum I
- Article: SCIENCE ADVANCES. 2022;8(17):eabn1823Bronge M; Hogelin KA; Thomas OG; Ruhrmann S; Carvalho-Queiroz C; Nilsson OB; Kaiser A; Zeitelhofer M; Holmgren E; Linnerbauer M; Adzemovic MZ; Hellstrom C; Jelcic I; Liu H; Nilsson P; Hillert J; Brundin L; Fink K; Kockum I; Tengvall K; Martin R; Tegel H; Graslund T; Al Nimer F; Guerreiro-Cacais AO; Khademi M; Gafvelin G; Olsson T; Gronlund H
- Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2020;8(1):207Gerhards R; Pfeffer LK; Lorenz J; Starost L; Nowack L; Thaler FS; Schlueter M; Ruebsamen H; Macrini C; Winklmeier S; Mader S; Bronge M; Groenlund H; Feederle R; Hsia H-E; Lichtenthaler SF; Merl-Pham J; Hauck SM; Kuhlmann T; Bauer IJ; Beltran E; Gerdes LA; Mezydlo A; Bar-Or A; Banwell B; Khademi M; Olsson T; Hohlfeld R; Lassmann H; Kuempfel T; Kawakami N; Meinl E
- Article: JOURNAL OF AUTOIMMUNITY. 2019;102:38-49Bronge M; Ruhrrnann S; Carvalho-Queiroz C; Nilsson OB; Kaiser A; Holmgren E; Macrini C; Winkhneier S; Meinl E; Brundin L; Khademi M; Olsson T; Gafvelin G; Gronlund H
- Article: METHODSX. 2019;6:1635-1641Sensitive detection of antigen-specific T-cells using bead-bound antigen for in vitro re-stimulationBronge M; Kaiser A; Carvalho-Queiroz C; Nilsson OB; Ruhrmann S; Holmgren E; Olsson T; Gafvelin G; Gronlund H
- Article: PLOS ONE. 2014;9(10):e111041Nilsson OB; Neimert-Andersson T; Bronge M; Grundstrom J; Sarma R; Uchtenhagen H; Kikhney A; Sandalova T; Holmgren E; Svergun D; Achour A; van Hage M; Gronlund H
All other publications
- Preprint: BIORXIV. 2025Thomas O; Rykaczewska U; Galešić M; van der Burgt R; Hallén N; Ferro F; Bronge M; Marti Z; Li Y; Riqué AH; Lin J; Krstic A; Gromadzka A; Szonder AL; Sorini C; Reina-Campos M; Sun T; Rubio Rodríguez-Kirby L; Dumral Ö; Berglund R; Kakhki MP; Adzemovic M; Zeitelhofer M; Akpinar B; Tengvall K; Nilsson O; Holmgren E; Cucuzza CS; Högelin KA; Gafvelin G; Fink K; Castelo-Branco G; Needhamsen M; Khademi M; Piehl F; Gräslund T; Alfredsson L; Lund H; Uhlén P; Kockum I; Martin R; Jagodic M; Grönlund H; Guerreiro-Cacais AO; Olsson T
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2025;31(3):243Rykaczewska U; Bronge M; Holmgren E; Piehl F; Gronlund H; Cacais AOG; Thomas O; Olsson T
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2024;30(3):8-9Thomas O; Rykaczewska U; Galesic M; Bronge M; van der Burgt R; Marti Z; Akpinar B; Rique AH; Adzemovic MZ; Hogelin KA; Nilsson O; Holmgren E; Gafvelin G; Khademi M; Al Nimer F; Piehl F; Graslund T; Martin R; Kockum I; Cacais AOG; Gronlund H; Olsson T
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2024;30(3):237Rykaczewska U; O'Gorman A; Ehrenborg L; Bronge M; Graslund T; Thomas O; Olsson T; Gronlund H
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:482-483Thomas O; Bronge M; Tengvall K; Akpinar B; Nilsson O; Holmgren E; Hessa T; Gafvelin G; Khademi M; Alfredsson L; Martin R; Cacais AOG; Gronlund H; Olsson T; Kockum I
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:36-37Thomas O; Rykaczewska U; Bronge M; Akpinar B; Naghavian R; Nilsson O; Holmgren E; Graslund T; Gafvelin G; Martin R; Gronlund H; Olsson T
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):234-235Thomas O; Bronge M; Hogelin KA; Carvalho-Queiroz C; Ruhrmann S; Nilsson O; Holmgren E; Graslund T; Martin R; Gafvelin G; Olsson T; Gronlund H
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):233-234Thomas O; Bronge M; Tengvall K; Gyllenberg A; Hellstrom C; Holmgren E; Graslund T; Khademi M; Martin R; Nilsson P; Gafvelin G; Gronlund H; Olsson T; Kockum I
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):344-345Bronge M; Asplund Hogelin K; Thomas OG; Ruhrmann S; Carvalho-Querioz C; Nilsson O; Kaiser A; Holmgren E; Linnerbauer M; Adzemovic MZ; Zeitelhofer M; Hellstrom C; Jelcic I; Liu H; Nilsson P; Hillert J; Brundin L; Fink K; Martin R; Tegel H; Graslund T; Al Nimer F; Guerreiro-Cacais AO; Khademi M; Gafvelin G; Olsson T; Gronlund H
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):50-51Thomas O; Bronge M; Hogelin KA; Carvalho-Querioz C; Nilsson O; Kaiser A; Holmgren E; Graslund T; Gafvelin G; Olsson T; Gronlund H
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:221Bronge M; Ruhrmann S; Carvalho-Queiroz C; Nilsson O; Kaiser A; Holmgren E; Macrini C; Winklmeier S; Meinl E; Brundin L; Khademi M; Olsson T; Gafvelin G; Groenlund H
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2014;79(6):477Bedri SK; Bronge M; Fink K; Lundstrom W; Glaser A; Gronlund H; Hillert J
Employments
- Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2026-2029
Degrees and Education
- Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2023
- Degree Of Master Of Science In Medicine, Karolinska Institutet, 2017